-
2
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441: 1162-1166
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
3
-
-
67649399288
-
Loss of pinkl function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Mar 10. Epub ahead of print
-
Dagda RK, Cherra SJ 3rd, Kulich SM, Tandon A, Park D, Chu CT (2009) Loss of pinkl function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem Mar 10. Epub ahead of print
-
(2009)
J Biol Chem
-
-
Dagda, R.K.1
Cherra 3rd, S.J.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
4
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng H, Dodson MW, Huang H, Guo M (2008) The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc Natl Acad Sci USA 105: 14503-14508
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
5
-
-
36049038504
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
-
Exner N, Treske B, Paquet D, HolmströmK, Schiesling C, Gispert S, Carballo-Carbajal I, Berg D, Hoepken HH, Gasser T et al. (2007) Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J Neurosci 27: 12413-12418
-
(2007)
J Neurosci
, vol.27
, pp. 12413-12418
-
-
Exner, N.1
Treske, B.2
Paquet, D.3
Holmström, K.4
Schiesling, C.5
Gispert, S.6
Carballo-Carbajal, I.7
Berg, D.8
Hoepken, H.H.9
Gasser, T.10
-
6
-
-
61649088435
-
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death
-
Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW et al. (2009) PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. Mol Cell 33: 627-638
-
(2009)
Mol Cell
, vol.33
, pp. 627-638
-
-
Gandhi, S.1
Wood-Kaczmar, A.2
Yao, Z.3
Plun-Favreau, H.4
Deas, E.5
Klupsch, K.6
Downward, J.7
Latchman, D.S.8
Tabrizi, S.J.9
Wood, N.W.10
-
7
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
Gautier CA, Kitada T, Shen J (2008) Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc Natl Acad Sci USA 105: 11364-11369
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
9
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe C, Beal MF (2008) Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat Clin Pract Neurol 4: 600-609
-
(2008)
Nat Clin Pract Neurol
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
10
-
-
33846288002
-
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6
-
Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Mulsch A, Nussbaum RL, Müller K, Dröse S, Brandt U et al. (2007) Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol Dis 25: 401-411
-
(2007)
Neurobiol Dis
, vol.25
, pp. 401-411
-
-
Hoepken, H.H.1
Gispert, S.2
Morales, B.3
Wingerter, O.4
Del Turco, D.5
Mulsch, A.6
Nussbaum, R.L.7
Müller, K.8
Dröse, S.9
Brandt, U.10
-
11
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim Y, Park J, Kim S, Song S, Kwon SK, Lee SH, Kitada T, Kim JM, Chung J (2008) PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem Biophys Res Commun 377: 975-980
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
Song, S.4
Kwon, S.K.5
Lee, S.H.6
Kitada, T.7
Kim, J.M.8
Chung, J.9
-
12
-
-
84864278260
-
PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease. PLoS ONE 4: E4597
-
Feb 26
-
Liu W, Vives-Bauza C, Acín-Peréz- R, Yamamoto A, Tan Y, Li Y, Magrané J, Stavarache MA, Shaffer S, Chang S et al. (2009) PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease. PLoS ONE 4: e4597. Epub 2009 Feb 26
-
(2009)
Epub
, pp. 2009
-
-
Liu, W.1
Vives-Bauza, C.2
Acín-Peréz-, R.3
Yamamoto, A.4
Tan, Y.5
Li, Y.6
Magrané, J.7
Stavarache, M.A.8
Shaffer, S.9
Chang, S.10
-
13
-
-
77953666757
-
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO
-
this issue
-
Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D et al. (2009) Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO Mol Med 1: this issue
-
(2009)
Mol Med
, vol.1
-
-
Morais, V.A.1
Verstreken, P.2
Roethig, A.3
Smet, J.4
Snellinx, A.5
Vanbrabant, M.6
Haddad, D.7
Frezza, C.8
Mandemakers, W.9
Vogt-Weisenhorn, D.10
-
14
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM et al. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441: 1157-1161
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
-
15
-
-
56349137588
-
Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation
-
Piccoli C, Sardanelli A, Scrima R, Ripoli M, Quarato G, D'Aprile A, Bellomo F, Scacco S, De Michele G, Filla A et al. (2008) Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation. Neurochem Res 33: 2565-2574
-
(2008)
Neurochem Res
, vol.33
, pp. 2565-2574
-
-
Piccoli, C.1
Sardanelli, A.2
Scrima, R.3
Ripoli, M.4
Quarato, G.5
D'Aprile, A.6
Bellomo, F.7
Scacco, S.8
De Michele, G.9
Filla, A.10
-
16
-
-
35748935851
-
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
-
Plun-Favreau H, Klupsch K, Moisoi N, Gandhi S, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N et al. (2007) The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol 9: 1243-1252
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1243-1252
-
-
Plun-Favreau, H.1
Klupsch, K.2
Moisoi, N.3
Gandhi, S.4
Kjaer, S.5
Frith, D.6
Harvey, K.7
Deas, E.8
Harvey, R.J.9
McDonald, N.10
-
17
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ, Pallanck LJ (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci USA 105: 1638-1643
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
18
-
-
34547127902
-
PINK1 Protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon JW, Olzmann JA, Chin LS, Li L (2007) PINK1 Protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol 5: e172
-
(2007)
PLoS Biol
, vol.5
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.S.3
Li, L.4
-
19
-
-
58549119743
-
Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase
-
Saotome M, Safiulina D, Szabadkai G, Das S, Fransson A, Aspenstrom P, Rizzuto R, Hajnóczky G (2008) Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase. Proc Natl Acad Sci USA 105: 20728-20733
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20728-20733
-
-
Saotome, M.1
Safiulina, D.2
Szabadkai, G.3
Das, S.4
Fransson, A.5
Aspenstrom, P.6
Rizzuto, R.7
Hajnóczky, G.8
-
20
-
-
49349102894
-
Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
-
Twig G, Hyde B, Shirihai OS (2008) Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta 1777: 1092-1097
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 1092-1097
-
-
Twig, G.1
Hyde, B.2
Shirihai, O.S.3
-
21
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Slelman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, et al. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304: 1158-1160
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Slelman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
-
22
-
-
64549112144
-
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking
-
Jan 20
-
Weihofen A, Thomas KJ, Ostaszewski BL, Cookson MR, Selkoe DJ (2009) Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry Jan 20
-
(2009)
Biochemistry
-
-
Weihofen, A.1
Thomas, K.J.2
Ostaszewski, B.L.3
Cookson, M.R.4
Selkoe, D.J.5
-
23
-
-
49349087497
-
-
PLoS
-
Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, et al. (2008) PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS ONE 3: e2455
-
(2008)
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
, vol.ONE 3
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Yao, Z.3
Abramov, A.Y.4
Miljan, E.A.5
Keen, G.6
Stanyer, L.7
Hargreaves, I.8
Klupsch, K.9
Deas, E.10
-
24
-
-
77953674786
-
-
Xiong H, Wang D, Chen L, Choo YS, Ma H, Tang C, Xia K, Jiang W, Ronai Z, Zhuang X, et al. (2009)
-
(2009)
-
-
Xiong, H.1
Wang, D.2
Chen, L.3
Choo, Y.S.4
Ma, H.5
Tang, C.6
Xia, K.7
Jiang, W.8
Ronai, Z.9
Zhuang, X.10
-
25
-
-
65649118917
-
-
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J Clin Invest 119: 650-660
-
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J Clin Invest 119: 650-660
-
-
-
-
26
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
-
Yang Y, Ouyang Y, Yang L, Beal MF, McQuibban A, Vogel H, Lu B (2008) Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proc Natl Acad Sci USA 105: 7070-7075
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
Lu, B.7
-
28
-
-
58149375389
-
Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo
-
Yun J, Cao JH, Dodson MW, Clark IE, Kapahi P, Chowdhury RB, Guo M (2008) Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo. J Neurosci 28: 14500-14510
-
(2008)
J Neurosci
, vol.28
, pp. 14500-14510
-
-
Yun, J.1
Cao, J.H.2
Dodson, M.W.3
Clark, I.E.4
Kapahi, P.5
Chowdhury, R.B.6
Guo, M.7
|