Pathogenesis of diabetic kidney disease: Review of cellular aspects of renal lesions

African Journal of Pharmacy and Pharmacology

Volumn 3, Issue 11, 2009, Pages 507-514

  Sahib, Mohanad Naji ^a   Abdulameer, Shaymaa Abdalwahed ^a   Aziz, Noorizan Abd ^a   Hassan, Yahaya ^a  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

Cellular and hemodynamic changes; Diabetic; Nephropathy

Indexed keywords

ANGIOTENSIN II; GLUCOSE; GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

DATA BASE; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX; GLOMERULUS BASEMENT MEMBRANE; HEMODYNAMICS; HEREDITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MORTALITY; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION;

EID: 77953656632     PISSN: None     EISSN: 19960816     Source Type: Journal    
DOI: None     Document Type: Review

References (56)

1. Bohle A, Wehrmann M, Bogenschutz O, Batz C, Muller CA Muller GA (1991). The pathogenesis of chronic renal failure in diabetic nephropathy. Investigation of 488 cases of diabetic glomerulosclerosis. Pathol. Res. Pract. 187: 251-259.
2. Border WA, Noble NA (1994). Transforming growth factor-β in tissue fibrosis. N. Engl. J. Med. 311: 1286-1292.
3. Böttinger EP, Bitzer M (2002). TGF-β Signaling in renal disease. J. Am. Soc. Nephrol. 13: 2600-2610.
4. Brasier AR, Jamaluddin M, Han Y, Patterson C, Runge MS (2000). Angiotensin II induces gene transcription through cell-type-dependent effects on the nuclear factor-β (NF-β) transcription factor. Mol. Cell Biochem. 212: 155-196.
5. Brownlee M (2001). Biochemistry and molecular cell biology of diabetic complications. Nature. 414: 813-820. (Pubitemid 34000785)
6. Catherwood Ma, Powell La, Anderson P, Mcmaster D, Sharpe PC, Trimble ER (2002). Glucose-induced oxidative stress in mesangial cells. Kidney Int. 61: 599-608. (Pubitemid 34102602)
7. Chen S, Cohen MP, Lautenslager GT, Shearman CW, Ziyadeh FN (2001). Glycated albumin stimulates TGF-β1 production and protein kinase C activity in glomerular endothelial cells. Kidney Int. 59: 673-681. (Pubitemid 32157932)
8. Chin BY, Mohsenin A, Li SX, Choi AM, Choi ME (2001). Stimulation of pro-α(1)(I) collagen by TGF-β1 in mesangial cells: Role pf the p38 MAPK pathway. Am. J. Physiol. Renal. Physiol. 280: F495-F504.
9. Dalla VM, Saller A, Bortoloso E, Mauer M, Fioretto P (2000). Structural involvement in type 1 and type 2 diabetic nephropathy. Diabetes Metab. 26: 8-14. (Pubitemid 30618351)
10. Fogarty DG, Rich SS, Hanna L (2000). Urinary albumin excretion in families with type 2 diabetes is heritable and genetically correlated to blood pressure. Kidney Int. 57: 250-257. (Pubitemid 30227772)
11. Gambara V, Mecca G, Remuzzi G, Bertani T (1993). Heterogeneous nature of renal lesions in type II diabetes. J. Am. Soc. Nephrol. 3: 1458-1466.
12. Gilbert RE, Cooper ME (1999). The tubulo-interstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury? Kidney Int. 56: 1627-1637.
13. Gnudi L, Gruden G, Viberti GC (2003). Pathogenesis of diabetic neprhopathy. IN PICKUP JC & WILLIAMS G (Eds.) Textbook of diabetes. 3rd ed. Oxford, Blackwell Science Ltd.
14. Gruden GZS, Hayward A (2000). Mechanical stretch-induced fibronectin and transforming growth factor beta 1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent. Diabetes. 49: 655-661.
15. Ha H, Lee HB (2000). Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose. Kidney Int. Suppl. 77: S19-S25.
16. Hsieh TI, Zhang SI, Filep JG, Tang SS, Ingelfinger JR Chan JS (2002). High glucose stimulates angiotensin gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. Endocrinol. 143: 2975-2985. (Pubitemid 34809870)
17. Isono M, Mogyorosi A, Han DC, Hoffman BB, Ziyadeh FN (2000). Stimulation of TGF-β type II receptor by high glucose in mouse mesangial cells and in diabetic kidney. Am. J. Physiol. 278: F830-F838.
18. Jaimes EA, Galceran JM, Raij L (1998). Angiotensin II induces superoxide anion production by mesangial cells. Kidney Int. 54: 775-784. (Pubitemid 28397395)
19. Jandeleit-Dahm K, Cooper ME (2002) Hypertension and diabetes. Curr. Opin. Nephrol. Hypertens. 11: 221-228.
20. Kanwar YS, Linker A, Farquhar MG (1980). Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion. J. Cell Biol. 86: 688-693. (Pubitemid 10016291)
21. Kolm V, Sauer U, Olgemooller B, Schleicher ED (1996). High glucose induced TGF-β1 regulates mesangial production of heparan sulfate proteoglycan. Am. J. Physiol. 270: F812-F821.
22. Kolm-Litty V, Sauer U, Nerlich A, Lehmann R, Schleicher ED (1998). High glucose-induced transforming growth factor-β1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. J. Clin. Invest. 101: 160-169.
23. Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King Gl, Kikkawa R (2000). Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC-β inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J. 14: 439-447. (Pubitemid 30143162)
24. Merta MRJ, Rysava R (2003). Genetics of diabetic nephropathy. Nephrol. Dial. Transplant. 18: 24-25.
25. Mogensen CE (1984). Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N. Engl. J. Med. 310: 356-360.
26. Mogensen CE, Christensen CK (1984). Predicting diabetic nephropathy in insulin-dependent patients. N. Engl. J. Med. 311: 89-93.
27. Nakamura T, Miller D, Ruoslahti E, Border WA (1992). Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1. Kidney Int. 41: 1213-1221.
28. Nosadini R, Velussi M, Brocco, E, Bruseghin M, Abaterusso C, Saller A, Dalla VM, Carraro A, Bortoloso E, Sambataro M, Barzon I, Frigato F, Muollo B, Chiesura-Corona M, Pacini G, Baggio B, Piarulli F, Sfriso A, Fioretto P. (2000). Course of renal function in type 2 diabetic patients with abnormalities of albumin excretion rate. Diabetes. 49: 476-484. (Pubitemid 30131795)
29. Ohba M, Shibanuma M, Kuroki T, Nose K (1994). Production of hydrogen peroxide by transforming growth factor-β1 and its in involvement in induction of egr-1 in mouse osteoblastic cells. J. Cell Biol. 126: 1079-1088. (Pubitemid 24252152)
30. Osterby R (1992). Glomerular structural changes in type 1 (insulin dependent) diabetes mellitus: Causes, consequences and prevention. Diabetologia. 35: 803-812.
31. Osterby R, Gall MA, Schmitz A, Nielsen FS, Nyberg G, Parving HH (1993). Glomerular structure and function in proteinuric type 2 (non-insulin- dependent) diabetic patients. Diabetologia. 36: 1064-1070. (Pubitemid 23288777)
32. Osterby R, Parving HH, Hommel E (1990). Glomerular structure and function in diabetic nephropathy. Diabetes. 39: 1057-1063.
33. Park IS, Kiyomoto H, Abboud SI, Abboud HE (1997). Expression of transforming growth factor- β and type IV collagen in early streptozotocin-induced diabetes. Diabetes. 46: 473-480. (Pubitemid 27090278)
34. Park SK, Kim J, Seomun Y, Choi J, Kim DH, Han IO, Lee EH, Chung SK, Joo CK (2001). Hydrogen peroxide is a novel inducer of connective tissue growth factor. Biochem. Biophys. Res. Commun. 284: 966-971.
35. Pavenstadt H, Kriz W, Kretzler M (2003). Cell biology of the podocyte. Physiol Rev, 83, 253-307.
36. Remuzzi A, Perico N, Amuchastegui Cs, Malanchini B, Mazerska M, Battaglia C, Bertani T & Remuzzi G (1993) Short- and long-term effect of angiotensin II receptor blockade in rats with experimental diabetes. J. Am. Soc. Nephrol. 4: 40-49.
37. Risdon RA, Sloper JC, Wardener HE (1968). Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet. 75: 363-366.
38. Ritz E, Orth SR (1999). Nephropathy in patients with type 2 diabetes mellitus. N. Eng.l J. Med. 341: 1127-1133.
39. Scivittaro V, Ganz MB Weiss MF (2000). AGEs induce oxidative stress and activate protein kinase C-β (II) in neonatal mesangial cells. Am. J. Physiol. Renal Physiol. 278, F676-F683.
40. Sharma K, Ziyadeh FN, Alzahabi B, Mcgowan TA, Kapoor S, Kurnik BRC, Kurnik PB, Weisberg LS (1997). Increased renal production of transforming growth factor-β1 in patients with type II diabetes. Diabetes. 26: 854-859. (Pubitemid 27188264)
41. Singh R, Alavi N, Singh AK, Leehey DJ (1999). Role of angiotensin II in glucose-induced inhibition of mesangial matrix degradation. Diabetes. 48: 2066-2073. (Pubitemid 29458373)
42. Steffes MW, Osterby R, Chavers B, Mauer SM (1989). Mesangial expansion as a central mechanism for loss of kidney function in diabetic patients. Diabetes. 38: 1077-1081. (Pubitemid 19250390)
43. Suzuki YI, Forman HI, Sevanian A (1997). Oxidants as stimulators of signal transduction. Free Radic. Biol. Med. 22: 269-285.
44. Ushio-Fukai-M, Zarari AM, Fukui T, Ishizaka N, Griendling KK (1996). p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates Angiotensin II-induced hypertrophy in vascular smooth muscle cells. J. Biol. Chem. 271: 23317-23321.
45. Valmadrid CT (2000). The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older-onset diabetes mellitus. Arch. Intern. Med. 160: 1093-1100.
46. Vernier RI, Steffes MW, Sisson-Ross S, Mauer SM (1992). Heparan sulfate proteoglycans in the glomerular basement membrane in type 1 diabetes mellitus. Kidney Int. 41: 1070-1080.
47. Viberti GC, Hill RD, Jarrett RJ, Argyropoulos A, Mahmud U, Keen H (1982). Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet. 1: 1430-1432.
48. Wang L, Zhu Y, Sharma K (1998). Transforming growth factor-β1 stimulates protein kinase A in mesangial cells. J. Biol. Chem. 273: 8522-8527.
49. Weigert C, Brodbeck K, Klopfer K, Haring HU, Schleicher ED (2002). Angiotensin II induces human TGF-β1 promoter activation: similarity to hyperglycemia. Diabetologia. 45: 89-898.
50. White KE, Bilous RW (2000). Type 2 diabetic patients with nephropathy show structural-functional relationships that are similar to type 1 disease. J. Am. Soc. Nephrol. 11: 1667-1673.
51. White KE, Bilous RW, Marshall SM (2002). Podocyte number in normotensive type 1 diabetic patients with albuminuria. Diabetes. 51: 3083-3089.
52. Wolf G (1998). Link between angiotensin II and TGF-β in the kidney. Miner Elect. Metab. 24: 174-180.
53. Wolf G, Ziyadeh FN (1997). The role of angiotensin II in diabetic nephropathy: Emphasis on nonhemodynamic mechanisms. Am. J. Kidney Dis. 29. 153-163.
54. Zatz R, Rentz DB, Mayer TW (1986). Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension. J. Clin. Invest. 77: 1925-1930.
55. Zeisbert M, Ericksen MB, Hamano Y, Neilson EG, Ziyadeh F, Kalluri R (2002). Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells. Biochem. Biophys. Res. Commun. 295. 401-407.
56. Ziyadeh Fn, Han Dc, Cohen Ja, Guo J, Cohen MP (1998). Glycated albumin stimulates fibronectin gene expression in glomerular mesangial cells: Involvement of the transforming growth factor beta system. Kidney Int. 53: 631-638. (Pubitemid 28124277)