A randomised controlled trial on melatonin and rosiglitazone for prevention of adhesion formation in a rat uterine horn model

Archives of Gynecology and Obstetrics

Volumn 282, Issue 1, 2010, Pages 55-61

  Aksakal, Orhan ^a   Yilmaz, Bulent ^a,d   Gungor, Tayfun ^a   Sirvan, Levent ^a   Sut, Necdet ^b   Inan, Ismet ^c   Kalyoncu, Senol ^a   Mollamahmutoglu, Leyla ^a  

^a ZEKAI TAHIR BURAK WOMEN S HEALTH EDUCATION AND RESEARCH HOSPITAL   (Turkey)

^b TRAKYA UNIVERSITY   (Turkey)

^c ANKARA TRAINING AND RESEARCH HOSPITAL   (Turkey)

^d NONE   (Turkey)

Author keywords

Adhesion prevention; Melatonin; Rat; Rosiglitazone; Uterine horn model

Indexed keywords

MELATONIN; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIOXIDANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; FEMALE; NONHUMAN; POSTOPERATIVE COMPLICATION; RAT; TREATMENT OUTCOME; UTERUS HORN; UTERUS SYNECHIA; WISTAR RAT; ANIMAL; INTRAPERITONEAL DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; PATHOLOGY; POSTOPERATIVE COMPLICATIONS; RANDOMIZATION; SURGERY; TISSUE ADHESIONS; UTERINE DISEASES; UTERUS;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; FEMALE; INJECTIONS, INTRAPERITONEAL; MELATONIN; POSTOPERATIVE COMPLICATIONS; RANDOM ALLOCATION; RATS; RATS, WISTAR; THIAZOLIDINEDIONES; TISSUE ADHESIONS; UTERINE DISEASES; UTERUS;

EID: 77953649302     PISSN: 09320067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00404-009-1240-8     Document Type: Article

References (49)

1. Z Alpay GM Saed MP Diamond 2008 Postoperative adhesions: from formation to prevention Semin Reprod Med 26 313 321 10.1055/s-0028-1082389 1:CAS:528:DC%2BD1cXhtFCisrfP 18756408 Review
2. MP Diamond JF Daniell J Feste, et al. 1987 Adhesion reformation and de novo adhesion formation after reproductive pelvic surgery Fertil Steril 47 864 866 1:STN:280:DyaL2s7ptFWgsw%3D%3D 2952528
3. MM Binda CR Molinas A Bastidas PR Koninckx 2007 Effect of reactive oxygen species scavengers, antiinflammatory drugs, and calcium-channel blockers on carbon dioxide pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model Surg Endosc 21 1826 1834 10.1007/s00464-007-9296-7 1:STN:280: DC%2BD2srjsVGlug%3D%3D 17479336 (Pubitemid 47404124)
4. MM Binda CR Molinas PR Koninckx 2003 Reactive oxygen species and adhesion formation: clinical implications in adhesion prevention Hum Reprod 18 2503 2507 10.1093/humrep/deg481 1:CAS:528:DC%2BD3sXpvVemurc%3D 14645163 Review (Pubitemid 37536612)
5. DM Portz TE Elkins R White, et al. 1991 Oxygen free radicals and pelvic adhesion formation: I. Blocking oxygen free radical toxicity to prevent adhesion formation in an endometriosis model Int J Fertil 36 39 42 1:CAS:528: DyaK3MXkt1ait7s%3D 1672675
6. B Ozcelik IS Serin M Basbug, et al. 2003 Effect of melatonin in the prevention of post-operative adhesion formation in a rat uterine horn adhesion model Hum Reprod 18 1703 1706 10.1093/humrep/deg337 12871886 (Pubitemid 36958054)
7. B Ustundag A Kazez M Demirbag, et al. 2000 Protective effect of melatonin on antioxidative system in experimental ischemia-reperfusion of rat small intestine Cell Physiol Biochem 10 229 236 10.1159/000016354 1:CAS:528: DC%2BD3MXjt1aktr8%3D 11093033
8. Y Okatani A Wakatsuki R Reiter, et al. 2003 Protective effect of melatonin against mitochondrial injury induced by ischemia and reperfusion of rat liver Eur J Pharmacol 469 145 152 10.1016/S0014-2999(03)01643-1 1:CAS:528:DC%2BD3sXktFGluro%3D 12782196 (Pubitemid 36629560)
9. C Kaur EA Ling 2008 Antioxidants and neuroprotection in the adult and developing central nervous system Curr Med Chem 15 3068 3080 10.2174/092986708786848640 1:CAS:528:DC%2BD1MXptV2huw%3D%3D 19075654 Review 11
10. H Tamura Y Nakamura A Korkmaz, et al. 2009 Melatonin and the ovary: physiological and pathophysiological implications Fertil Steril 92 328 343 10.1016/j.fertnstert.2008.05.016 1:CAS:528:DC%2BD1MXhtFWisLrP 18804205 Review
11. S Demirbag S Cetinkursun U Tasdemir, et al. 2005 Comparison of hyaluronate/carboxymethylcellulose membrane and melatonin for prevention of adhesion formation in a rat model Hum Reprod 20 2021 2024 10.1093/humrep/deh846 1:CAS:528:DC%2BD2MXmvF2ks74%3D 15802326 (Pubitemid 40932393)
12. C Ara H Kirimlioglu AB Karabulut, et al. 2005 Protective effect of melatonin against oxidative stress on adhesion formation in the rat cecum and uterine horn model Life Sci 77 1341 1350 10.1016/j.lfs.2005.01.024 1:CAS:528:DC%2BD2MXlvFehsLk%3D 15958275 (Pubitemid 40943675)
13. A Hatipoglu Z Turkyilmaz S Mert 2007 The effect of melatonin on postoperative intraabdominal adhesion formation Yonsei Med J 48 659 664 10.3349/ymj.2007.48.4.659 1:CAS:528:DC%2BD2sXhtFarsLnI 17722239 (Pubitemid 47496729)
14. MM Binda CR Molinas A Bastidas PR Koninckx 2007 Effect of reactive oxygen species scavengers, antiinflammatory drugs, and calcium-channel blockers on carbon dioxide pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model Surg Endosc 21 1826 1834 10.1007/s00464-007-9296-7 1:STN:280: DC%2BD2srjsVGlug%3D%3D 17479336 (Pubitemid 47404124)
15. γ) as a regulator of monocyte/macrophage function J Leukoc Biol 66 733 739 1:CAS:528: DyaK1MXnsVanu78%3D 10577502
16. γ, promotes expression of catalase, and reduces inflammation, behavioral dysfunction, and neuronal loss after intracerebral hemorrhage in rats J Cereb Blood Flow Metab 26 811 820 10.1038/sj.jcbfm.9600233 1:CAS:528:DC%2BD28XmtVOht7s%3D 16208315
17. DG Johns Z Ao M Eybye, et al. 2005 Rosiglitazone protects against ischemia/reperfusion-induced leukocyte adhesion in the zucker diabetic fatty rat J Pharmacol Exp Ther 315 1020 1027 10.1124/jpet.105.090993 1:CAS:528: DC%2BD2MXhtlalurrI 16123307 (Pubitemid 41637837)
18. S Giannini M Serio A Galli 2004 Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity J Endocrinol Invest 27 982 991 1:CAS:528:DC%2BD2MXhvFCrsr0%3D 15762051 Review
19. RM Touyz EL Schiffrin 2006 Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications Vascul Pharmacol 45 19 28 10.1016/j.vph.2005.11.014 1:CAS:528:DC%2BD28XmsFSrtLo%3D 16782410 Review (Pubitemid 43963482)
20. F Demirturk H Aytan A Caliskan, et al. 2006 The effect of rosiglitazone in the prevention of intra-abdominal adhesion formation in a rat uterine horn model Hum Reprod 21 3008 3013 10.1093/humrep/del258 1:CAS:528:DC%2BD28XhtVynsrzL 16997937 (Pubitemid 44567020)
21. S Kelekci B Yilmaz S Oguz, et al. 2004 The efficacy of a hyaluronate/carboxymethylcellulose membrane in prevention of postoperative adhesion in a rat uterine horn model Tohoku J Exp Med 204 189 194 10.1620/tjem.204.189 1:CAS:528:DC%2BD2cXhtVShsbbM 15502417 (Pubitemid 39619136)
22. S Kelekci D Uygur B Yilmaz, et al. 2007 Comparison of human amniotic membrane and hyaluronate/carboxymethylcellulose membrane for prevention of adhesion formation in rats Arch Gynecol Obstet 276 355 359 10.1007/s00404-007- 0376-7 1:CAS:528:DC%2BD2sXhtVaktrnK 17492299 (Pubitemid 47397562)
23. B Yilmaz O Aksakal T Gungor, et al. 2009 Metformin and atorvastatin reduce adhesion formation in a rat uterine horn model Reprod Biomed Online 18 436 442 10.1016/S1472-6483(10)60106-X 1:CAS:528:DC%2BD1MXhtVKkurnM 19298747
24. RE Leach JW Burns EJ Dawe, et al. 1998 Reduction of postsurgical adhesion formation in the rabbit uterine horn model with use of hyaluronate/ carboxymethylcellulose gel Fertil Steril 69 415 418 10.1016/S0015-0282(97)00573- 6 1:STN:280:DyaK1c7ptlShsg%3D%3D 9531869 (Pubitemid 28146549)
25. GD Hooker BM Taylor DK Driman 1999 Prevention of adhesion formation with use of sodium hyaluronate-based bioresorbable membrane in a rat model of ventral hernia repair with polypropylene mesh-a randomized, controlled study Surgery 125 211 216 1:STN:280:DyaK1M7ltVyiug%3D%3D 10026756
26. MA Weibel G Manjo 1973 Peritoneal adhesions and their relation to abdominal surgery Am J Surg 126 345 353 10.1016/S0002-9610(73)80123-0 1:STN:280:DyaE3s3ksl2mtA%3D%3D 4580750
27. D Menzies H Ellis 1990 Intestinal obstruction from adhesions: how big is the problem? Ann R Coll Surg Engl 72 60 63 1:STN:280:DyaK3c7ks1SnsQ%3D%3D 2301905
28. D Menzies 1992 Peritoneal adhesions: incidence, cause and prevention Surg Ann 24 27 45
29. B Risberg 1997 Adhesions: preventive strategies Eur J Surg Suppl 577 32 39 9076450
30. H Ellis 1997 The clinical significance of adhesions: focus on intestinal obstruction Eur J Surg Suppl 577 5 9 9076446
31. T Tulandi MF Chen S Al-Took K Watkin 1998 A study of nerve fibers and histopathology of postsurgical, postinfectious and endometriosis-related adhesions Obstet Gynecol 92 766 768 10.1016/S0029-7844(98)00298-1 1:STN:280:DyaK1M%2FgvVOqtA%3D%3D 9794665 (Pubitemid 28487671)
32. T Liakakos N Thomakos PM Fine, et al. 2001 Peritoneal adhesions: etiology, pathophysiology, and clinical significance. Recent advances in prevention and management Dig Surg 18 260 273 10.1159/000050149 1:STN:280:DC%2BD3MvosFKhsQ%3D%3D 11528133 (Pubitemid 32786145)
33. DiZerega GS (2000) Peritoneal surgery. Springer, New York
34. C Nappi A Di Spiezio Sardo E Greco, et al. 2007 Prevention of adhesions in gynaecological endoscopy Hum Reprod Update 13 379 394 10.1093/humupd/dml061 1:STN:280:DC%2BD2svisl2isw%3D%3D 17452399 (Pubitemid 47062830)
35. CM Drollette SZA Badawy 1992 Pathophysiology of pelvic adhesions: modern trends in preventing infertility J Reprod Med 37 107 122 1:STN:280: DyaK387mslWmtg%3D%3D 1371547
36. di Zerega GS (1992) The peritoneum: postsurgical repair and adhesion formation. In: Rock JA, Murphy AA, Jones HW (eds) Female reproductive surgery. Williams & Wilkins, Baltimore, pp 2-18
37. KE Rodgers GS di Zerega 1993 Function of peritoneal exudate cells after abdominal surgery J Invest Surg 6 9 23 10.3109/08941939309141188 1:STN:280:DyaK3s3gtVSrsg%3D%3D 8452827
38. P Escher W Wahli 2000 Peroxisome proliferators-activated receptors: insights into multiple cellular functions Mutat Res 448 121 138 1:CAS:528:DC%2BD3cXhvV2ksbo%3D 10725467
39. C Jiang AT Ting B Seed 1998 PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines Nature 391 82 86 10.1038/35154 1:CAS:528:DyaK1cXktVSgug%3D%3D 9422509 (Pubitemid 28086550)
40. N Marx G Sukhova C Murphy, et al. 1998 Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma (PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro Am J Pathol 153 17 23 1:CAS:528:DyaK1cXks1Grs7w%3D 9665460
41. JC Fantone PA Ward 1982 Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions Am J Pathol 107 395 418 1:STN:280:DyaL383gtlOjsg%3D%3D 6282132
42. F de la Portilla I Ynfante D Bejarano, et al. 2004 Prevention of peritoneal adhesions by intraperitoneal administration of vitamin E: an experimental study in rats Dis Colon Rectum 47 2157 2161 10.1007/s10350-004- 0741-6 (Pubitemid 40179080)
43. RJ Reiter DX Tan C Osuna E Gitto 2000 Actions of melatonin in the reduction of oxidative status J Biomed Sci 7 444 458 10.1007/BF02253360 1:CAS:528:DC%2BD3cXos1yjtb0%3D 11060493
44. M Allegra RJ Reiter DX Tan, et al. 2003 The chemistry of melatonin's interaction with reactive species J Pineal Res 34 1 10 10.1034/j.1600-079X.2003. 02112.x 1:CAS:528:DC%2BD3sXntVGnsA%3D%3D 12485365 (Pubitemid 36140351)
45. C Rodriguez JC Mayo RM Sainz, et al. 2004 Regulation of antioxidant enzymes: a significant role for melatonin J Pineal Res 36 1 9 10.1046/j.1600-079X.2003.00092.x 1:CAS:528:DC%2BD2cXotFKltQ%3D%3D 14675124 (Pubitemid 38130283)
46. AM Carossino A Lombardi M Matucci-Cerinic A Pignone M Cagnoni 1996 Effect of melatonin on normal and sclerodermic skin fibroblast proliferation Clin Exp Rheumatol 14 493 498 1:STN:280:DyaK2s%2FntVOhtg%3D%3D 8913650
47. C Leach GA Thorburn 1980 Comparison of inhibitory effects of melatonin and indomethacin on platelet aggregation and thromboxane release Prostaglandins 20 51 56 10.1016/0090-6980(80)90005-2 1:CAS:528:DyaL3cXlt1Kjur0%3D 7403573 (Pubitemid 10031263)
48. MF Gimeno A Landa N Sterin-Speziale, et al. 1980 Melatonin blocks in vitro generation of prostaglandin by the uterus and hypothalamus Eur J Pharmacol 62 309 317 10.1016/0014-2999(80)90098-9 1:CAS:528:DyaL3cXktVWitrs%3D 6102921 (Pubitemid 10156766)
49. D Wallwiener A Meyer G Bastert 1998 Adhesion formation of the parietal and visceral peritoneum: an explanation for the controversy on the use of autologous and alloplastic barriers? Fertil Steril 69 132 137 10.1016/S0015-0282(97)00429-9 1:STN:280:DyaK1c7hslWmsA%3D%3D 9457948 Review (Pubitemid 28075613)