메뉴 건너뛰기




Volumn 184, Issue 12, 2010, Pages 6592-6599

High-affinity B cell receptor ligation by cognate antigen induces cytokine-independent isotype switching

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B LYMPHOCYTE RECEPTOR; CYTOKINE; IMMUNOGLOBULIN G1; INTERLEUKIN 4; STAT6 PROTEIN; HEN EGG LYSOZYME; LYMPHOCYTE ANTIGEN RECEPTOR; LYSOZYME;

EID: 77953647800     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903437     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 0030022218 scopus 로고    scopus 로고
    • Antibody class switching
    • Stavnezer, J. 1996. Antibody class switching. Adv. Immunol. 61: 79-146.
    • (1996) Adv. Immunol. , vol.61 , pp. 79-146
    • Stavnezer, J.1
  • 4
    • 0024385049 scopus 로고
    • Rapid induction of transcription of unrearranged s(gamma)1 switch regions in activated murine B cells by interleukin 4
    • Esser, C., and A. Radbruch. 1989. Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4. EMBO J. 8: 483-488. (Pubitemid 19274967)
    • (1989) EMBO Journal , vol.8 , Issue.2 , pp. 483-488
    • Esser, C.1    Radbruch, A.2
  • 5
    • 0022353594 scopus 로고
    • Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1
    • Vitetta, E. S., J. Ohara, C. D. Myers, J. E. Layton, P. H. Krammer, and W. E. Paul. 1985. Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1. J. Exp. Med. 162: 1726-1731.
    • (1985) J. Exp. Med. , vol.162 , pp. 1726-1731
    • Vitetta, E.S.1    Ohara, J.2    Myers, C.D.3    Layton, J.E.4    Krammer, P.H.5    Paul, W.E.6
  • 6
    • 0022568935 scopus 로고
    • B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells
    • Coffman, R. L., J. Ohara, M. W. Bond, J. Carty, A. Zlotnik, and W. E. Paul. 1986. B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J. Immunol. 136: 4538-4541.
    • (1986) J. Immunol. , vol.136 , pp. 4538-4541
    • Coffman, R.L.1    Ohara, J.2    Bond, M.W.3    Carty, J.4    Zlotnik, A.5    Paul, W.E.6
  • 7
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper, C. M., and W. E. Paul. 1987. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236: 944-947.
    • (1987) Science , vol.236 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 8
    • 0026525387 scopus 로고
    • Induction of IgG3 secretion by interferon gamma: A model for T cell-independent class switching in response to T cell-independent type 2 antigens
    • Snapper, C. M., T. M. McIntyre, R. Mandler, L. M. Pecanha, F. D. Finkelman, A. Lees, and J. J. Mond. 1992. Induction of IgG3 secretion by interferon gamma: a model for T cell-independent class switching in response to T cell-independent type 2 antigens. J. Exp. Med. 175: 1367-1371.
    • (1992) J. Exp. Med. , vol.175 , pp. 1367-1371
    • Snapper, C.M.1    McIntyre, T.M.2    Mandler, R.3    Pecanha, L.M.4    Finkelman, F.D.5    Lees, A.6    Mond, J.J.7
  • 9
    • 0027523093 scopus 로고
    • Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells
    • McIntyre, T. M., D. R. Klinman, P. Rothman, M. Lugo, J. R. Dasch, J. J. Mond, and C. M. Snapper. 1993. Transforming growth factor beta 1 selectivity stimulates immunoglobulin G2b secretion by lipopolysaccharide-activated murine B cells. J. Exp. Med. 177: 1031-1037.
    • (1993) J. Exp. Med. , vol.177 , pp. 1031-1037
    • McIntyre, T.M.1    Klinman, D.R.2    Rothman, P.3    Lugo, M.4    Dasch, J.R.5    Mond, J.J.6    Snapper, C.M.7
  • 10
    • 0024446350 scopus 로고
    • Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes
    • Coffman, R. L., D. A. Lebman, and B. Shrader. 1989. Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide- stimulated murine B lymphocytes. J. Exp. Med. 170: 1039-1044.
    • (1989) J. Exp. Med. , vol.170 , pp. 1039-1044
    • Coffman, R.L.1    Lebman, D.A.2    Shrader, B.3
  • 11
    • 0026540646 scopus 로고
    • Differential regulation of IgA production by TGF-beta and IL-5: TGF-beta induces surface IgA-positive cells bearing IL-5 receptor, whereas IL-5 promotes their survival and maturation into IgA-secreting cells
    • Sonoda, E., Y. Hitoshi, N. Yamaguchi, T. Ishii, A. Tominaga, S. Araki, and K. Takatsu. 1992. Differential regulation of IgA production by TGF-beta and IL-5: TGF-beta induces surface IgA-positive cells bearing IL-5 receptor, whereas IL-5 promotes their survival and maturation into IgA-secreting cells. Cell. Immunol. 140: 158-172.
    • (1992) Cell. Immunol. , vol.140 , pp. 158-172
    • Sonoda, E.1    Hitoshi, Y.2    Yamaguchi, N.3    Ishii, T.4    Tominaga, A.5    Araki, S.6    Takatsu, K.7
  • 12
    • 4043108358 scopus 로고    scopus 로고
    • Divide and conquer: The importance of cell division in regulating B-cell responses
    • Tangye, S. G., and P. D. Hodgkin. 2004. Divide and conquer: the importance of cell division in regulating B-cell responses. Immunology 112: 509-520.
    • (2004) Immunology , vol.112 , pp. 509-520
    • Tangye, S.G.1    Hodgkin, P.D.2
  • 13
    • 0030037519 scopus 로고    scopus 로고
    • B cell differentiation and isotype switching is related to division cycle number
    • Hodgkin, P. D., J. H. Lee, and A. B. Lyons. 1996. B cell differentiation and isotype switching is related to division cycle number. J. Exp. Med. 184: 277-281.
    • (1996) J. Exp. Med. , vol.184 , pp. 277-281
    • Hodgkin, P.D.1    Lee, J.H.2    Lyons, A.B.3
  • 14
    • 0347756722 scopus 로고    scopus 로고
    • Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation
    • Hasbold, J., L. M. Corcoran, D. M. Tarlinton, S. G. Tangye, and P. D. Hodgkin. 2004. Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat. Immunol. 5: 55-63.
    • (2004) Nat. Immunol. , vol.5 , pp. 55-63
    • Hasbold, J.1    Corcoran, L.M.2    Tarlinton, D.M.3    Tangye, S.G.4    Hodgkin, P.D.5
  • 15
    • 0032757402 scopus 로고    scopus 로고
    • Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation
    • Deenick, E. K., J. Hasbold, and P. D. Hodgkin. 1999. Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation. J. Immunol. 163: 4707-4714.
    • (1999) J. Immunol. , vol.163 , pp. 4707-4714
    • Deenick, E.K.1    Hasbold, J.2    Hodgkin, P.D.3
  • 16
    • 0026743070 scopus 로고
    • Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen
    • Brink, R., C. C. Goodnow, J. Crosbie, E. Adams, J. Eris, D. Y. Mason, S. B. Hartley, and A. Basten. 1992. Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen. J. Exp. Med. 176: 991-1005.
    • (1992) J. Exp. Med. , vol.176 , pp. 991-1005
    • Brink, R.1    Goodnow, C.C.2    Crosbie, J.3    Adams, E.4    Eris, J.5    Mason, D.Y.6    Hartley, S.B.7    Basten, A.8
  • 17
    • 0016277747 scopus 로고
    • Inhibition of mitogenic stimulation of mouse lymphocytes by anti-mouse immunoglobulin antibodies. I. Mode of action
    • Andersson, J., W. W. Bullock, and F. Melchers. 1974. Inhibition of mitogenic stimulation of mouse lymphocytes by anti-mouse immunoglobulin antibodies. I. Mode of action. Eur. J. Immunol. 4: 715-722.
    • (1974) Eur. J. Immunol. , vol.4 , pp. 715-722
    • Andersson, J.1    Bullock, W.W.2    Melchers, F.3
  • 18
    • 0017891304 scopus 로고
    • B cell differentiation induced by lipopolysaccharide. V. Suppression of plasma cell maturation by anti-mu: Mode of action and characteristics of suppressed cells
    • Kearney, J. F., J. Klein, D. E. Bockman, M. D. Cooper, and A. R. Lawton. 1978. B cell differentiation induced by lipopolysaccharide. V. Suppression of plasma cell maturation by anti-mu: mode of action and characteristics of suppressed cells. J. Immunol. 120: 158-166.
    • (1978) J. Immunol. , vol.120 , pp. 158-166
    • Kearney, J.F.1    Klein, J.2    Bockman, D.E.3    Cooper, M.D.4    Lawton, A.R.5
  • 19
    • 33749522228 scopus 로고    scopus 로고
    • ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation
    • Rui, L., J. I. Healy, J. Blasioli, and C. C. Goodnow. 2006. ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation. J. Immunol. 177: 5337-5346.
    • (2006) J. Immunol. , vol.177 , pp. 5337-5346
    • Rui, L.1    Healy, J.I.2    Blasioli, J.3    Goodnow, C.C.4
  • 20
    • 0037087296 scopus 로고    scopus 로고
    • Cross-linking surface Ig delays CD40 ligand- and IL-4-induced B cell Ig class switching and reveals evidence for independent regulation of B cell proliferation and differentiation
    • Rush, J. S., J. Hasbold, and P. D. Hodgkin. 2002. Cross-linking surface Ig delays CD40 ligand- and IL-4-induced B cell Ig class switching and reveals evidence for independent regulation of B cell proliferation and differentiation. J. Immunol. 168: 2676-2682.
    • (2002) J. Immunol. , vol.168 , pp. 2676-2682
    • Rush, J.S.1    Hasbold, J.2    Hodgkin, P.D.3
  • 21
    • 33750502877 scopus 로고    scopus 로고
    • High affinity germinal center B cells are actively selected into the plasma cell compartment
    • Phan, T. G., D. Paus, T. D. Chan, M. L. Turner, S. L. Nutt, A. Basten, and R. Brink. 2006. High affinity germinal center B cells are actively selected into the plasma cell compartment. J. Exp. Med. 203: 2419-2424.
    • (2006) J. Exp. Med. , vol.203 , pp. 2419-2424
    • Phan, T.G.1    Paus, D.2    Chan, T.D.3    Turner, M.L.4    Nutt, S.L.5    Basten, A.6    Brink, R.7
  • 22
    • 0037390660 scopus 로고    scopus 로고
    • B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells
    • Phan, T. G., M. Amesbury, S. Gardam, J. Crosbie, J. Hasbold, P. D. Hodgkin, A. Basten, and R. Brink. 2003. B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J. Exp. Med. 197: 845-860.
    • (2003) J. Exp. Med. , vol.197 , pp. 845-860
    • Phan, T.G.1    Amesbury, M.2    Gardam, S.3    Crosbie, J.4    Hasbold, J.5    Hodgkin, P.D.6    Basten, A.7    Brink, R.8
  • 25
    • 0028262128 scopus 로고
    • Determination of lymphocyte division by flow cytometry
    • Lyons, A. B., and C. R. Parish. 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171: 131-137.
    • (1994) J. Immunol. Methods , vol.171 , pp. 131-137
    • Lyons, A.B.1    Parish, C.R.2
  • 26
    • 33645856486 scopus 로고    scopus 로고
    • Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation
    • Paus, D., T. G. Phan, T. D. Chan, S. Gardam, A. Basten, and R. Brink. 2006. Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation. J. Exp. Med. 203: 1081-1091.
    • (2006) J. Exp. Med. , vol.203 , pp. 1081-1091
    • Paus, D.1    Phan, T.G.2    Chan, T.D.3    Gardam, S.4    Basten, A.5    Brink, R.6
  • 27
    • 58149087247 scopus 로고    scopus 로고
    • Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR
    • Cicinnati, V. R., Q. Shen, G. C. Sotiropoulos, A. Radtke, G. Gerken, and S. Beckebaum. 2008. Validation of putative reference genes for gene expression studies in human hepatocellular carcinoma using real-time quantitative RT-PCR. BMC Cancer 8: 350.
    • (2008) BMC Cancer , vol.8 , pp. 350
    • Cicinnati, V.R.1    Shen, Q.2    Sotiropoulos, G.C.3    Radtke, A.4    Gerken, G.5    Beckebaum, S.6
  • 28
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102: 553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 29
    • 0018724478 scopus 로고
    • Surface Ig isotypes on cells responding to lipopolysaccharide by IgM and IgG secretion
    • Gronowicz, E. S., C. Doss, F. Assisi, E. S. Vitetta, R. L. Coffman, and S. Strober. 1979. Surface Ig isotypes on cells responding to lipopolysaccharide by IgM and IgG secretion. J. Immunol. 123: 2049-2056.
    • (1979) J. Immunol. , vol.123 , pp. 2049-2056
    • Gronowicz, E.S.1    Doss, C.2    Assisi, F.3    Vitetta, E.S.4    Coffman, R.L.5    Strober, S.6
  • 31
    • 0024443148 scopus 로고
    • Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes
    • Morgado, M. G., P. Cam, C. Gris-Liebe, P. A. Cazenave, and E. Jouvin-Marche. 1989. Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes. EMBO J. 8: 3245-3251.
    • (1989) EMBO J. , vol.8 , pp. 3245-3251
    • Morgado, M.G.1    Cam, P.2    Gris-Liebe, C.3    Cazenave, P.A.4    Jouvin-Marche, E.5
  • 32
    • 0031859134 scopus 로고    scopus 로고
    • STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination
    • Linehan, L. A., W. D. Warren, P. A. Thompson, M. J. Grusby, and M. T. Berton. 1998. STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. J. Immunol. 161: 302-310.
    • (1998) J. Immunol. , vol.161 , pp. 302-310
    • Linehan, L.A.1    Warren, W.D.2    Thompson, P.A.3    Grusby, M.J.4    Berton, M.T.5
  • 33
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
    • Lin, J. X., T. S. Migone, M. Tsang, M. Friedmann, J. A. Weatherbee, L. Zhou, A. Yamauchi, E. T. Bloom, J. Mietz, S. John, et al. 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 2: 331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.X.1    Migone, T.S.2    Tsang, M.3    Friedmann, M.4    Weatherbee, J.A.5    Zhou, L.6    Yamauchi, A.7    Bloom, E.T.8    Mietz, J.9    John, S.10
  • 35
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kühn, R., K. Rajewsky, and W. Müller. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254: 707-710. (Pubitemid 21917392)
    • (1991) Science , vol.254 , Issue.5032 , pp. 707-710
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 36
    • 33845447720 scopus 로고    scopus 로고
    • Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21
    • Jin, H., and T. R. Malek. 2006. Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21. J. Leukoc. Biol. 80: 1416-1423.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 1416-1423
    • Jin, H.1    Malek, T.R.2
  • 39
    • 0028022805 scopus 로고
    • Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site
    • Lundgren, M., C. Larsson, A. Femino, M. Xu, J. Stavnezer, and E. Severinson. 1994. Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site. J. Immunol. 153: 2983-2995.
    • (1994) J. Immunol. , vol.153 , pp. 2983-2995
    • Lundgren, M.1    Larsson, C.2    Femino, A.3    Xu, M.4    Stavnezer, J.5    Severinson, E.6
  • 40
    • 0035424899 scopus 로고    scopus 로고
    • Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40
    • Mao, C. S., and J. Stavnezer. 2001. Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40. J. Immunol. 167: 1522-1534.
    • (2001) J. Immunol. , vol.167 , pp. 1522-1534
    • Mao, C.S.1    Stavnezer, J.2
  • 41
    • 0028971990 scopus 로고
    • Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals
    • Warren, W. D., and M. T. Berton. 1995. Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals. J. Immunol. 155: 5637-5646.
    • (1995) J. Immunol. , vol.155 , pp. 5637-5646
    • Warren, W.D.1    Berton, M.T.2
  • 43
    • 38949145383 scopus 로고    scopus 로고
    • Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion
    • Heltemes-Harris, L. M., P. J. Gearhart, P. Ghosh, and D. L. Longo. 2008. Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion. Mol. Immunol. 45: 1799-1806.
    • (2008) Mol. Immunol. , vol.45 , pp. 1799-1806
    • Heltemes-Harris, L.M.1    Gearhart, P.J.2    Ghosh, P.3    Longo, D.L.4
  • 46
    • 0017187483 scopus 로고
    • B lymphocyte differentiation induced by lipopolysaccharide. III. Suppression of B cell maturation by anti-mouse immunoglobulin antibodies
    • Kearney, J. F., M. D. Cooper, and A. R. Lawton. 1976. B lymphocyte differentiation induced by lipopolysaccharide. III. Suppression of B cell maturation by anti-mouse immunoglobulin antibodies. J. Immunol. 116: 1664-1668.
    • (1976) J. Immunol. , vol.116 , pp. 1664-1668
    • Kearney, J.F.1    Cooper, M.D.2    Lawton, A.R.3
  • 47
    • 0034105621 scopus 로고    scopus 로고
    • Absence of lipopolysaccharide high-dose paralysis in B-cell responses: Implications for the one-signal theory
    • Mamchak, A. A., and P. D. Hodgkin. 2000. Absence of lipopolysaccharide high-dose paralysis in B-cell responses: implications for the one-signal theory. Immunol. Cell Biol. 78: 133-141.
    • (2000) Immunol. Cell Biol. , vol.78 , pp. 133-141
    • Mamchak, A.A.1    Hodgkin, P.D.2
  • 48
    • 0029002360 scopus 로고
    • The one signal theory of B cell activation revisited: A role for surface immunoglobulin in regulating T-independent antibody responses?
    • Mamchak, A. A., and P. D. Hodgkin. 1995. The one signal theory of B cell activation revisited: a role for surface immunoglobulin in regulating T-independent antibody responses? Immunol. Cell Biol. 73: 266-271.
    • (1995) Immunol. Cell Biol. , vol.73 , pp. 266-271
    • Mamchak, A.A.1    Hodgkin, P.D.2
  • 49
    • 0026763868 scopus 로고
    • Inhibition of lipopolysaccharide-induced activation of immature B cells by anti-mu and anti-delta antibodies and its modulation by interleukin-4
    • Brines, R. D., and G. G. Klaus. 1992. Inhibition of lipopolysaccharide- induced activation of immature B cells by anti-mu and anti-delta antibodies and its modulation by interleukin-4. Int. Immunol. 4: 765-771.
    • (1992) Int. Immunol. , vol.4 , pp. 765-771
    • Brines, R.D.1    Klaus, G.G.2
  • 50
    • 0026007124 scopus 로고
    • The influence of avidity on signaling murine B lymphocytes with monoclonal anti-IgM antibodies. Effects of B cell proliferation versus growth inhibition (tolerance) of an immature B cell lymphoma
    • Udhayakumar, V., L. Kumar, and B. Subbarao. 1991. The influence of avidity on signaling murine B lymphocytes with monoclonal anti-IgM antibodies. Effects of B cell proliferation versus growth inhibition (tolerance) of an immature B cell lymphoma. J. Immunol. 146: 4120-4129.
    • (1991) J. Immunol. , vol.146 , pp. 4120-4129
    • Udhayakumar, V.1    Kumar, L.2    Subbarao, B.3
  • 51
    • 0021346615 scopus 로고
    • Allotypic specificities of murine IgD and IgM recognized by monoclonal antibodies
    • Stall, A. M., and M. R. Loken. 1984. Allotypic specificities of murine IgD and IgM recognized by monoclonal antibodies. J. Immunol. 132: 787-795.
    • (1984) J. Immunol. , vol.132 , pp. 787-795
    • Stall, A.M.1    Loken, M.R.2
  • 52
    • 0023870852 scopus 로고
    • Production of rat monoclonal antibody from rat x mouse hybridoma cell lines using microencapsulation technology
    • Gilligan, K. J., S. Littlefield, and A. P. Jarvis, Jr. 1988. Production of rat monoclonal antibody from rat x mouse hybridoma cell lines using microencapsulation technology. In Vitro Cell. Dev. Biol. 24: 35-41.
    • (1988) In Vitro Cell. Dev. Biol. , vol.24 , pp. 35-41
    • Gilligan, K.J.1    Littlefield, S.2    Jarvis Jr., A.P.3
  • 53
    • 0021244743 scopus 로고
    • Induction of resting B cells to DNA synthesis by soluble monoclonal anti-immunoglobulin
    • Julius, M. H., C. H. Heusser, and K. U. Hartmann. 1984. Induction of resting B cells to DNA synthesis by soluble monoclonal anti-immunoglobulin. Eur. J. Immunol. 14: 753-757.
    • (1984) Eur. J. Immunol. , vol.14 , pp. 753-757
    • Julius, M.H.1    Heusser, C.H.2    Hartmann, K.U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.