-
1
-
-
33644610520
-
The genetics of Parkinson disease: Implications for neurological care
-
DOI 10.1038/ncpneuro0126, PII N0126
-
Klein C, Schlossmacher MG. The genetics of Parkinson disease: implications for neurological care. Nat Clin Pract Neurol. 2006;2(3):136-146. (Pubitemid 43307390)
-
(2006)
Nature Clinical Practice Neurology
, vol.2
, Issue.3
, pp. 136-146
-
-
Klein, C.1
Schlossmacher, M.G.2
-
2
-
-
0021337873
-
Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey
-
Langston JW, Forno LS, Rebert CS, Irwin I. Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey. Brain Res. 1984;292(2):390-394.
-
(1984)
Brain Res
, vol.292
, Issue.2
, pp. 390-394
-
-
Langston, J.W.1
Forno, L.S.2
Rebert, C.S.3
Irwin, I.4
-
3
-
-
32044453150
-
Pesticides and Parkinson's disease - Is there a link?
-
Brown TP, Rumsby PC, Capleton AC, Rushton L, Levy LS. Pesticides and Parkinson's disease - is there a link? Environ Health Perspect. 2006;114(2):156-164.
-
(2006)
Environ Health Perspect
, vol.114
, Issue.2
, pp. 156-164
-
-
Brown, T.P.1
Rumsby, P.C.2
Capleton, A.C.3
Rushton, L.4
Levy, L.S.5
-
4
-
-
70449370469
-
Professional exposure to pesticides and Parkinson's disease
-
Elbaz A, Clavel J, Rathouz PJ, et al. Professional exposure to pesticides and Parkinson's disease. Ann Neurol. 2009;66(4):494-504.
-
(2009)
Ann Neurol
, vol.66
, Issue.4
, pp. 494-504
-
-
Elbaz, A.1
Clavel, J.2
Rathouz, P.J.3
-
5
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
DOI 10.1073/pnas.86.2.695
-
Cordon-Cardo C, O'Brien JP, Casals D, et al. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc Natl Acad Sci U S A. 1989;86(2):695-698. (Pubitemid 19037807)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.2
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
6
-
-
0030297401
-
Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein
-
Bain LJ, LeBlanc GA. Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein. Toxicol Appl Pharmacol. 1996;141 (1):288-298.
-
(1996)
Toxicol Appl Pharmacol
, vol.141
, Issue.1
, pp. 288-298
-
-
Bain, L.J.1
LeBlanc, G.A.2
-
7
-
-
34249983462
-
Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function
-
Sreeramulu K, Liu R, Sharom FJ. Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function. Biochim Biophys Acta. 2007; 1768(7):1750-1757.
-
(2007)
Biochim Biophys Acta
, vol.1768
, Issue.7
, pp. 1750-1757
-
-
Sreeramulu, K.1
Liu, R.2
Sharom, F.J.3
-
8
-
-
18644367631
-
Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease
-
DOI 10.1097/00008571-200210000-00004
-
Furuno T, Landi MT, Ceroni M, et al. Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease. Pharmacogenetics. 2002;12(7):529-534. (Pubitemid 35177082)
-
(2002)
Pharmacogenetics
, vol.12
, Issue.7
, pp. 529-534
-
-
Furuno, T.1
Landi, M.-T.2
Ceroni, M.3
Caporaso, N.4
Bernucci, I.5
Nappi, G.6
Martignoni, E.7
Schaeffeler, E.8
Eichelbaum, M.9
Schwab, M.10
Zanger, U.M.11
-
9
-
-
0038241171
-
Polymorphism in the P-glycoprotein drug transporter MDR1 gene: A possible link between environmental and genetic factors in Parkinson's disease
-
DOI 10.1097/00008571-200305000-00004
-
Droździk M, Bialecka M, Mysliwiec K, Honczarenko K, Stankiewicz J, Sych Z. Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease. Pharmacogenetics. 2003;13(5):259-263. (Pubitemid 36583992)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.5
, pp. 259-263
-
-
Drozdzik, M.1
Bialecka, M.2
Mysliwiec, K.3
Honczarenko, K.4
Stankiewicz, J.5
Sych, Z.6
-
10
-
-
3042720631
-
MDR1, the blood-brain barrier transporter, is associated with Parkinson's disease in ethnic Chinese
-
Lee CG, Tang K, Cheung YB, et al. MDR1, the blood-brain barrier transporter, is associated with Parkinson's disease in ethnic Chinese. J Med Genet. 2004; 41(5):e60.
-
(2004)
J Med Genet
, vol.41
, Issue.5
-
-
Lee, C.G.1
Tang, K.2
Cheung, Y.B.3
-
11
-
-
20044365400
-
Effect of MDR1 haplotype on risk of Parkinson disease
-
Tan EK, Chan DK, Ng PW, et al. Effect of MDR1 haplotype on risk of Parkinson disease. Arch Neurol. 2005;62(3):460-464.
-
(2005)
Arch Neurol
, vol.62
, Issue.3
, pp. 460-464
-
-
Tan, E.K.1
Chan, D.K.2
Ng, P.W.3
-
12
-
-
62149090278
-
MDR1 variants and risk of Parkinson disease: Association with pesticide exposure?
-
Zschiedrich K, Konig IR, Bruggemann N, et al. MDR1 variants and risk of Parkinson disease: association with pesticide exposure? J Neurol. 2009;256(1): 115-120.
-
(2009)
J Neurol
, vol.256
, Issue.1
, pp. 115-120
-
-
Zschiedrich, K.1
Konig, I.R.2
Bruggemann, N.3
-
13
-
-
67449091266
-
Association of a polymorphism in the ABCB1 gene with Parkinson's disease
-
Westerlund M, Belin AC, Anvret A, et al. Association of a polymorphism in the ABCB1 gene with Parkinson's disease. Parkinsonism Relat Disord. 2009;15 (6):422-424.
-
(2009)
Parkinsonism Relat Disord
, vol.15
, Issue.6
, pp. 422-424
-
-
Westerlund, M.1
Belin, A.C.2
Anvret, A.3
-
14
-
-
0032946784
-
Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990
-
Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990. Neurology. 1999; 52(6):1214-1220.
-
(1999)
Neurology
, vol.52
, Issue.6
, pp. 1214-1220
-
-
Bower, J.H.1
Maraganore, D.M.2
McDonnell, S.K.3
Rocca, W.A.4
-
15
-
-
0029787622
-
Nontraditional epidemiologic approaches in the analysis of gene-environment interaction: Case-control studies with no controls!
-
Khoury MJ, Flanders WD. Nontraditional epidemiologic approaches in the analysis of gene-environment interaction: case-control studies with no controls! Am J Epidemiol. 1996;144(3):207-213.
-
(1996)
Am J Epidemiol
, vol.144
, Issue.3
, pp. 207-213
-
-
Khoury, M.J.1
Flanders, W.D.2
-
16
-
-
1442329302
-
CYP2D6 Polymorphism, Pesticide Exposure, and Parkinson's Disease
-
DOI 10.1002/ana.20051
-
Elbaz A, Levecque C, Clavel J, et al. CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease. Ann Neurol. 2004;55(3):430-434. (Pubitemid 38269597)
-
(2004)
Annals of Neurology
, vol.55
, Issue.3
, pp. 430-434
-
-
Elbaz, A.1
Levecque, C.2
Clavel, J.3
Vidal, J.-S.4
Richard, F.5
Amouyel, P.6
Alperovitch, A.7
Chartier-Harlin, M.-C.8
Tzourio, C.9
-
17
-
-
7944230914
-
Analysis of MDR1 haplotypes in Parkinson's disease in a white population
-
Tan EK, Drozdzik M, Bialecka M, et al. Analysis of MDR1 haplotypes in Parkinson's disease in a white population. Neurosci Lett. 2004;372(3):240-244.
-
(2004)
Neurosci Lett
, vol.372
, Issue.3
, pp. 240-244
-
-
Tan, E.K.1
Drozdzik, M.2
Bialecka, M.3
-
18
-
-
0032564134
-
Parkinson's disease, pesticides, and glutathione transferase polymorphisms
-
DOI 10.1016/S0140-6736(98)03453-9
-
Menegon A, Board PG, Blackburn AC, Mellick GD, Le Couteur DG. Parkinson's disease, pesticides, and glutathione transferase polymorphisms. Lancet. 1998; 352(9137):1344-1346. (Pubitemid 28510915)
-
(1998)
Lancet
, vol.352
, Issue.9137
, pp. 1344-1346
-
-
Menegon, A.1
Board, P.G.2
Blackburn, A.C.3
Mellick, G.D.4
Le Couteur, D.G.5
-
19
-
-
33749565743
-
5′ and 3′ region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: A hypothesis-generating study
-
Kelada SN, Checkoway H, Kardia SL, et al. 5′ and 3′ region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating study. Hum Mol Genet. 2006;15(20):3055-3062.
-
(2006)
Hum Mol Genet
, vol.15
, Issue.20
, pp. 3055-3062
-
-
Kelada, S.N.1
Checkoway, H.2
Kardia, S.L.3
-
20
-
-
67449159281
-
Dopamine transporter genetic variants and pesticides in Parkinson's disease
-
Ritz BR, Manthripragada AD, Costello S, et al. Dopamine transporter genetic variants and pesticides in Parkinson's disease. Environ Health Perspect. 2009; 117(6):964-969.
-
(2009)
Environ Health Perspect
, vol.117
, Issue.6
, pp. 964-969
-
-
Ritz, B.R.1
Manthripragada, A.D.2
Costello, S.3
-
21
-
-
0030012558
-
Possible environmental, occupational, and other etiologic factors for Parkinson's disease: A case-control study in Germany
-
Seidler A, Hellenbrand W, Robra BP, et al. Possible environmental, occupational, and other etiologic factors for Parkinson's disease: a case-control study in Germany. Neurology. 1996;46(5):1275-1284. (Pubitemid 26159286)
-
(1996)
Neurology
, vol.46
, Issue.5
, pp. 1275-1284
-
-
Seidler, A.1
Hellenbrand, W.2
Robra, B.-P.3
Vieregge, P.4
Nischan, P.5
Joerg, J.6
Oertel, W.H.7
Ulm, G.8
Schneider, E.9
-
22
-
-
14844365725
-
Parkinson's disease among Inuit in Greenland: Organochlorines as risk factors
-
Koldkjaer OG, Wermuth L, Bjerregaard P. Parkinson's disease among Inuit in Greenland: organochlorines as risk factors. Int J Circumpolar Health. 2004;63(suppl 2):366-368.
-
(2004)
Int J Circumpolar Health
, vol.63
, Issue.SUPPL. 2
, pp. 366-368
-
-
Koldkjaer, O.G.1
Wermuth, L.2
Bjerregaard, P.3
-
23
-
-
42449155102
-
Pesticide exposure and risk of Parkinson's disease: A family-based case-control study
-
Hancock DB, Martin ER, Mayhew GM, et al. Pesticide exposure and risk of Parkinson's disease: a family-based case-control study. BMC Neurol. 2008;8(6):6.
-
(2008)
BMC Neurol
, vol.8
, Issue.6
, pp. 6
-
-
Hancock, D.B.1
Martin, E.R.2
Mayhew, G.M.3
-
24
-
-
67650462977
-
Elevated serum pesticide levels and risk of Parkinson disease
-
Richardson JR, Shalat SL, Buckley B, et al. Elevated serum pesticide levels and risk of Parkinson disease. Arch Neurol. 2009;66(7):870-875.
-
(2009)
Arch Neurol
, vol.66
, Issue.7
, pp. 870-875
-
-
Richardson, J.R.1
Shalat, S.L.2
Buckley, B.3
-
25
-
-
46149118192
-
Impact of dietary exposure to food contaminants on the risk of Parkinson's disease
-
Petersen MS, Halling J, Bech S, et al. Impact of dietary exposure to food contaminants on the risk of Parkinson's disease. Neurotoxicology. 2008;29(4): 584-590.
-
(2008)
Neurotoxicology
, vol.29
, Issue.4
, pp. 584-590
-
-
Petersen, M.S.1
Halling, J.2
Bech, S.3
-
26
-
-
30344472393
-
Metabolism of DDT in different tissues of young rats
-
Tebourbi O, Driss MR, Sakly M, Rhouma KB. Metabolism of DDT in different tissues of young rats. J Environ Sci Health B. 2006;41(2):167-176.
-
(2006)
J Environ Sci Health B
, vol.41
, Issue.2
, pp. 167-176
-
-
Tebourbi, O.1
Driss, M.R.2
Sakly, M.3
Rhouma, K.B.4
-
27
-
-
0034712093
-
Organochlorine insecticides in substantia nigra in Parkinson's disease
-
Corrigan FM, Wienburg CL, Shore RF, Daniel SE, Mann D. Organochlorine insecticides in substantia nigra in Parkinson's disease. J Toxicol Environ Health A. 2000;59(4):229-234.
-
(2000)
J Toxicol Environ Health A
, vol.59
, Issue.4
, pp. 229-234
-
-
Corrigan, F.M.1
Wienburg, C.L.2
Shore, R.F.3
Daniel, S.E.4
Mann, D.5
-
28
-
-
0035036218
-
Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways
-
Kirby ML, Barlow RL, Bloomquist JR. Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways. Toxicol Sci. 2001; 61(1):100-106.
-
(2001)
Toxicol Sci
, vol.61
, Issue.1
, pp. 100-106
-
-
Kirby, M.L.1
Barlow, R.L.2
Bloomquist, J.R.3
-
29
-
-
0035581423
-
Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptopic cell death in dopaminergic cells
-
DOI 10.1016/S0891-5849(01)00726-2, PII S0891584901007262
-
Kitazawa M, Anantharam V, Kanthasamy AG. Dieldrin-induced oxidative stress and neurochemical changes contribute to apoptotic cell death in dopaminergic cells. Free Radic Biol Med. 2001;31(11):1473-1485. (Pubitemid 33145318)
-
(2001)
Free Radical Biology and Medicine
, vol.31
, Issue.11
, pp. 1473-1485
-
-
Kitazawa, M.1
Anantharam, V.2
Kanthasamy, A.G.3
-
30
-
-
0033030440
-
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease
-
Miller GW, Erickson JD, Perez JT, et al. Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp Neurol. 1999; 156(1):138-148.
-
(1999)
Exp Neurol
, vol.156
, Issue.1
, pp. 138-148
-
-
Miller, G.W.1
Erickson, J.D.2
Perez, J.T.3
-
31
-
-
0032863057
-
Heptachlor alters expression and function of dopamine transporters
-
Miller GW, Kirby ML, Levey AI, Bloomquist JR. Heptachlor alters expression and function of dopamine transporters. Neurotoxicology. 1999;20(4):631-637.
-
(1999)
Neurotoxicology
, vol.20
, Issue.4
, pp. 631-637
-
-
Miller, G.W.1
Kirby, M.L.2
Levey, A.I.3
Bloomquist, J.R.4
-
32
-
-
23844461866
-
Dieldrin-induced neurotoxicity: Relevance to Parkinson's disease pathogenesis
-
DOI 10.1016/j.neuro.2004.07.010, PII S0161813X04001135
-
Kanthasamy AG, Kitazawa M, Kanthasamy A, Anantharam V. Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis. Neurotoxicology. 2005;26(4):701-719. (Pubitemid 41175903)
-
(2005)
NeuroToxicology
, vol.26
, Issue.4 SPEC. ISSUE
, pp. 701-719
-
-
Kanthasamy, A.G.1
Kitazawa, M.2
Kanthasamy, A.3
Anantharam, V.4
-
33
-
-
34047172474
-
Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system
-
Hatcher JM, Richardson JR, Guillot TS, et al. Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system. Exp Neurol. 2007; 204(2):619-630.
-
(2007)
Exp Neurol
, vol.204
, Issue.2
, pp. 619-630
-
-
Hatcher, J.M.1
Richardson, J.R.2
Guillot, T.S.3
-
34
-
-
0027132062
-
Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug- Resistant breast cancer cells
-
Phang JM, Poore CM, Lopaczynska J, Yeh GC. Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells. Cancer Res. 1993;53(24):5977-5981. (Pubitemid 24006169)
-
(1993)
Cancer Research
, vol.53
, Issue.24
, pp. 5977-5981
-
-
Phang, J.M.1
Poore, C.M.2
Lopaczynska, J.3
Grace Chao, Y.4
-
35
-
-
0026490937
-
A new functional role for P-glycoprotein: Efflux pump for benzo(alpha)pyrene in human breast cancer MCF-7 cells
-
Yeh GC, Lopaczynska J, Poore CM, Phang JM. A new functional role for P-glycoprotein: efflux pump for benzo(alpha)pyrene in human breast cancer MCF-7 cells. Cancer Res. 1992;52(23):6692-6695.
-
(1992)
Cancer Res
, vol.52
, Issue.23
, pp. 6692-6695
-
-
Yeh, G.C.1
Lopaczynska, J.2
Poore, C.M.3
Phang, J.M.4
-
36
-
-
13844253394
-
Differential effects of the organochlorine pesticide DDT and its metabolite p,p'-DDE on pglycoprotein activity and expression
-
Shabbir A, DiStasio S, Zhao J, Cardozo CP, Wolff MS, Caplan AJ. Differential effects of the organochlorine pesticide DDT and its metabolite p,p'-DDE on pglycoprotein activity and expression. Toxicol Appl Pharmacol. 2005;203(2): 91-98.
-
(2005)
Toxicol Appl Pharmacol
, vol.203
, Issue.2
, pp. 91-98
-
-
Shabbir, A.1
DiStasio, S.2
Zhao, J.3
Cardozo, C.P.4
Wolff, M.S.5
Caplan, A.J.6
-
37
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel AH, Smit JJ, van Tellingen O, et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell. 1994;77(4):491-502.
-
(1994)
Cell
, vol.77
, Issue.4
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
-
38
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
Kimchi-Sarfaty C, Oh JM, Kim IW, et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science. 2007;315(5811):525- 528.
-
(2007)
Science
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimchi-Sarfaty, C.1
Oh, J.M.2
Kim, I.W.3
-
39
-
-
33749989048
-
MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells
-
Salama NN, Yang Z, Bui T, Ho RJ. MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells. J Pharm Sci. 2006;95(10):2293-2308.
-
(2006)
J Pharm Sci
, vol.95
, Issue.10
, pp. 2293-2308
-
-
Salama, N.N.1
Yang, Z.2
Bui, T.3
Ho, R.J.4
-
40
-
-
0037183584
-
Neurotoxicity induced by tacrolimus after liver transplantation: Relation to genetic polymorphisms of the ABCB1 (MDR1) gene
-
Yamauchi A, Ieiri I, Kataoka Y, et al. Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene. Transplantation. 2002;74(4):571-572.
-
(2002)
Transplantation
, vol.74
, Issue.4
, pp. 571-572
-
-
Yamauchi, A.1
Ieiri, I.2
Kataoka, Y.3
-
42
-
-
31344432977
-
Effect of organophosphate pesticide diazinon on expression and activity of intestinal P-glycoprotein
-
Lecoeur S, Videmann B, Mazallon M. Effect of organophosphate pesticide diazinon on expression and activity of intestinal P-glycoprotein. Toxicol Lett. 2006; 161(3):200-209.
-
(2006)
Toxicol Lett
, vol.161
, Issue.3
, pp. 200-209
-
-
Lecoeur, S.1
Videmann, B.2
Mazallon, M.3
-
43
-
-
2342512261
-
Effect of chlorpyrifos on efflux transporter gene expression and function in Caco-2 cells
-
Agarwala S, Chen W, Cook TJ. Effect of chlorpyrifos on efflux transporter gene expression and function in Caco-2 cells. Toxicol In Vitro. 2004;18(4):403-409.
-
(2004)
Toxicol In Vitro
, vol.18
, Issue.4
, pp. 403-409
-
-
Agarwala, S.1
Chen, W.2
Cook, T.J.3
|