Characterization of the variable region within class 1 integrons in Klebsiella pneumoniae nosocomials strains;Caracterización de la región variable de integrones clase 1 presentes en cepas nosocomiales de Klebsiella pneumoniae

Revista Medica de Chile

Volumn 138, Issue 3, 2010, Pages 322-329

  Guzmán, Militza ^a,b   Alonso, Guillermina ^b  

^a UNIVERSIDAD DE ORIENTE   (Venezuela)

^b FACULTAD DE CIENCIAS   (Venezuela)

Author keywords

Bacterial infections; Integrons; Klebsiella pneumoniae

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL DNA;

ARTICLE; CROSS INFECTION; DRUG EFFECT; GENETICS; HUMAN; INTEGRON; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MULTIDRUG RESISTANCE; POLYMERASE CHAIN REACTION;

ANTI-BACTERIAL AGENTS; CROSS INFECTION; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; INTEGRONS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION;

EID: 77953641053     PISSN: 00349887     EISSN: 07176163     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Gupta A, Ampolo K, Rubenstein D, Saiman L. Extended spectrum ß-lactamase-producing Klebsiella pneumoniae infections: a review of the literature. J Perinatol 2003; 23: 439-43.
2. Carattoli A. Plasmid-mediated antimicrobial resistance in Salmonella entérica. Curr Issues Mol Biol 2003; 5: 113-22.
3. Rowe-Magnus DA, Davies J, Mazel D. Impact of integrons and transposons on the evolution of resistance and virulence. Curr Top Microbiol Immunol 2002; 264: 167-88.
4. Partridge SR, Brown H, Stokes W, Hall RM. Transposons Tnl696 and Tn21 and their integrons In4 and In2 have independent origins. Antimicrob Agents Chemother 2001;45:1263-70.
5. Collis C, Hall R. Expression of antibiotic resistence genes in the integrated cassettes of integrons. Antimicrob Agents Chemother 1995; 39: 155-62.
6. Hall R, Stokes H. Integrons. Novel DNA elements which capture genes by site-specific recombinations. Genetics 1993; 90: 115-32.
7. González G, Mella S, Zemelman R, Bello H, Domínguez Y. Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos. Rev Med Chile 2004; 132:619-26.
8. Stokes H, Hall R. A novel family of potentially mobile DNA elements encoding site specific gene integration functions: integrons. Mol Microbiol 1989; 3: 1669-83.
9. Collis C, Hall R. Site-specific deletion and rearrangement of insert genes catalyzed by the DNA integrase. J Bacteriol 1992; 174: 1574-85.
10. Fluit A, Schmitz FJ. Resistance integrons and superintegrons. Clin Microbiol Infec 2004; 10: 272-88.
11. Podschum R, Ullmann U. Klebsiella spp. as nosocomial pathogens: Epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 1998; 11: 589-603.
12. Gales C, Jones R, Gordon K, Sader H, Wilke W, Beach M. Activity and spectrum of antimicrobial agents tested again urinary tract infection pathogens in hospitalized patients in Latin America: report from the second year of the SENTRY antimicrobial surveillance program. J Antimicrob Chemother 1998; 45: 295-303.
13. Byarugaba D. View on antimicrobial resistance in developing countries and responsable risk factors. Int J Antimicrob Agents 2004; 24: 105-10.
14. Yang H, Chen H, Yang Q, Chen M, Wang H. High Prevalence of Plasmid-Mediated Quinolone Resistance Genes qnr and aac(6)-Ib-cr in Clinical Isolates of Enterobacteriaceae from Nine Teaching Hospitals in China. Antimicrob Agents chemother 2008; 52: 4268-73.
15. Yao F, Quian Y, Chen S, Wang P, Huang Y. Incidence of Extended-spectrum ß-lactamases and characterization of integrones in extended-spectrum ß-Lactamase-producing Klebsiella pneumoniae Isolated in Shantou, China. Acta Bioch Bioph Sin 2007; 39: 527-32.
16. Shi W, Zhou J, Quin J. Transconjugation and genotyping of the plasmid-mediated AmpC ß-lactamase and extended-spectrum ß-lactamase genes in Klebsiella pneumoniae. Chi Med J 2009; 12: 1090-6.
17. Clinical and Laboratery Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing; eigthteenth informational supplement, MI 00-S18. CLSI 2008. Wayne, PA.
18. Levesqué C, Pichel L, Larose C, Roy P. PCR mapping of integran reveals several novel combinations of resistance genes. Antimicrob Agents Chemother 1995; 39: 185-91.
19. Narváez P, Pedroza R, Alonso G, Rodríguez-Lemoine V. Caracterización de plásmidos de resistencia a antibióticos en aislados nosocomiales del Hospital Universitario de Caracas. Rev Soc Ven Microbiol 2005; 25: 29-34.
20. Sambrook I, Russell D. Molecular cloning a laboratory manual. 3a Edition. Cold Spring Harbor: New York: 2001.
21. Altschul SF, Madden TL, Schaffer AA, et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997; 25: 3389-402.
22. Essack S, Hall L, Livermore D. Klebsiella pneumoniae isolate from South Africa with moltiple TEM, SHV and AmpC piactamases. Int J Antimicrob Agents 2004; 23: 398-400.
23. Schjorring S, Struve C, Krogfelt KA. Transfer of antimicrobial resistance plasmids from Klebsiella pneumoniae to Escherichia coli in the mouse intestine. J Antimicrob Chemother 2008; 62: 1086-93.
24. Labuschange C, Weldhagen GF, Ehlers MM, Dove MG. Emergence of class 1 integron-associated GES-5 and GES-5-like extended-spectrum beta-lactamases in clinical isolates of Pseudomonas aeruginosa in South Africa. Int J antimicrob Agents 2008; 31: 527-30.
25. Boucher Y, Labbate M, Koenig JE, Stokes HW. Integrons: mobilizable platforms that promote genetic diversity in bacteria. Trends Microbiol 2007; 15: 301-309.
26. Reyes A, Bello H, Domínguez M, Mella S, Zemelman R, Gonzáles G. Prevalence and types of class 1 integrons in aminoglycoside-resistant Enterobacteriaceae from several Chilean hospitals. J Antimicrob Chemother 2003; 51: 317-21.
27. Alonso G, Malaver E, Guzmán M, Rodríguez V. Caracterización de plásmidos e integrones presentes en bacterias multirresistentes aisladas en diferentes ambientes de Venezuela. MIBE 2005; 4: 81-84.
28. Zhang H, Shi L, Li L, Guo S, Zhang X, Yamasaki S, et al. Identification and Characterization of Class 1 Integran Resistance Gene Cassettes among Salmonella Strains Isolated from Healthy Humans in China. Microbiol Immunol 2004; 48: 639-45.
29. Álvarez-Fernández M, Rodríguez-Sousa T, Brey-Fernández E, López-Meléndez C, Pifleiro L. Asociación entre integrones de clase 1 con resistencia a múltiples antimicrobianos y plásmidos conjugativos en Enterobacteriacea. RevEsp Quimioterap 2003; 16: 394-7.
30. Torres L, Benítez M, Domínguez M, Torres O, Gagliotta V, Calvo A, et al. Detección de integrones clase 1 en cepas de enterobacterias productoras de -lactamasas de espectro expandido tipo SHV y CTX-M grupo 2. VITAE Academia Biomédica digital. 2005; 25: Disponible en http://caibco.ucv.ve/. [Acceso 2 de julio de 2008].
31. Fluit Ac, Schmitz J. Class 1 integrons, gene cassettes mobility, and epidemiology. Eur J Clin Microbiol Infect Dis 1999; 18: 761-70.
32. Wu JJ, Ko WC, Tsai SH, Yan JJ. Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital. Antimicrob Agents Chemother 2007; 51: 1223-7.
33. White P, Melver C, Rawlinson W. Integrons and gene cassette in Enterobacteriaceae. Antimicrob Agents Chemother 2001; 45: 2658-61.
34. Pallecchi L, Lucchetti C, Bartoloni A, Bartalesi F, Mantella A, Gamboa H, et al. Population Structure and Resistance Genes in Antibiotic-Resistant Bacteria from a Remote Community with Minimal Antibiotic Exposure. Antimicrob Agents Chemother 2007; 51: 1179-84.
35. Lee IC, Oh JY, Cho JW, Park JC, Kim JM, Seol SY, et al. The prevalence of trimethoprim-resistance-conferring dihydrofolate reducíase genes in urinary isolates of Escherichia coli in Korea. I Antimicrob Chemother 2001; 47: 599-604.
36. France A, Kugeler KM, Freeman A, Zalewski CA, Blahna M, Lixin Z, et al. Clonal Groups and the Spread of Resistance to Trimethoprim-Sulfamethoxazole in Uropathogenic Escherichia coli. Clin Infect Dis 2005; 40: 1101-7.
37. Yu HS, Lee IC, Kang HY, Leong YS, Lee EY, Choi CH, et al. Prevalence of dfr genes associated with integrons and dissemination of dfrA17 among urinary isolates of Escherichia coli in Korea. I Antimicrob chemother 2004; 53: 445-50.
38. Iones L, Melver C, Kim M, Rawlinson W, White R. The aadB gene cassette is associated whith blaSHV genes in Klebsiella species producing extended-spectrum -lactamases. Antimicrob Agents Chemother 2005; 49: 794-7.
39. Centron D, Roy PH. Characterization of the 6'-N-aminoglycoside acetyltransferase gene aac(6')-Iq from the integran of a natural multiresistance plasmid. Antimicrob agents Chemother 1998; 42: 1506-8.
40. Fonseca EL, Mykytczuk OL, Asensi MD, Reis EM, Ferraz LR, Paula FL, et al. Clonality and Antimicrobial Resistance Gene Pretiles of Multidrug-Resistant Salmonella entérica Serovar Infantis Isolates from Four Public Hospitals in Rio de laneiro, Brazil. I Clin Microbiol 2006; 4: 2767-72.