Klebsiella pneumoniae isolate from South Africa with multiple TEM, SHV and AmpC β-lactamases

International Journal of Antimicrobial Agents

Volumn 23, Issue 4, 2004, Pages 398-400

  Essack, Sabiha Y ^a   Hall, Lucinda M C ^b   Livermore, David M ^c  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

AmpC lactamase; Extended spectrum lactamases; K. pneumoniae

Indexed keywords

AZTREONAM; BACTERIAL ENZYME; BETA LACTAMASE; BETA LACTAMASE AMPC; BETA LACTAMASE INHIBITOR; CEFALOTIN; CEFEPIME; CEFOXITIN; CEFTAZIDIME; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; IMIPENEM; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; PROTEIN SHV; PROTEIN TEM; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; DNA HYBRIDIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE IDENTIFICATION; GENETIC CODE; ISOELECTRIC POINT; KLEBSIELLA PNEUMONIAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SOUTH AFRICA;

BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BETA-LACTAMS; HUMANS; ISOELECTRIC FOCUSING; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; SOUTH AFRICA;

EID: 1842637862     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2003.08.010     Document Type: Article

References (14)

1. Livermore D.M. β-Lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:1995;557-584.
2. CMY-1 gene and its relationship with other β-lactamases genes. Antimicrob. Agents Chemother. 40:1996;1926-1930.
3. Koh TH, Babini GS, Woodford N, Hall LMC, Sng LH, Livermore DM. Carbapenem-hydrolysing IMP-1 β-lactamase in Klebsiella pneumoniae from Singapore. Lancet 1999;353:2162.
4. Essack S.Y., Alexander D.M., Pillay B. A 'novel' plasmid-mediated, class I-type β-lactamase isolated in Klebsiella pneumoniae in Durban, South Africa. Med. Sci. Res. 22:1994;797-798.
5. 2 and pH on inhibition of TEM-1 and other β-lactamases by penicillanic acid sulfones. Antimicrob. Agents Chemother. 36:1992;1870-1876.
6. Livermore DM, Williams JD. β-Lactams: mode of action and mechanisms of bacterial resistance. In: Lorian V, editor. Antibiotics in laboratory medicine. 4th ed. 502-506 Baltimore: Williams & Wilkins; 1996.
7. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. 2nd ed. New York: Cold Spring Harbor Laboratory; 1989.
8. Kado C.I., Liu S.T. Rapid procedure for detection and isolation of large and small plasmids. J. Bacteriol. 145:1981;1365-1373.
9. Ambler R.P., Coulson A.F., Frère J -M. A standard numbering scheme for the class A β-lactamases. Biochem. J. 276:1991;269-270.
10. Knox J.R. Extended-spectrum and inhibitor-resistant TEM-type β-lactamases: mutations, specificity, and three-dimensional structure. Antimicrob. Agents Chemother. 39:1995;2593-2601.
11. Pitout J.D.D., Thomson K.S., Hanson N.D., Ehrhardt A.F., Moland E.S., Sanders C.C. β-Lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia coli and Proteus mirabilis isolates recovered in South Africa. Antimicrob. Agents Chemother. 42:1998;1350-1354.
12. Danel F., Hall L.M.C., Duke B., Gur D., Livermore D.M. OXA-17, a further extended-spectrum variant of OXA-10 β-lactamases isolated from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 43:1999;1362-1366.
13. Essack S.Y., Hall L.M., Pillay D.G., McFadyen M.L., Livermore D.M. Complexity and diversity of Klebsiella pneumoniae strains with extended-spectrum beta-lactamases isolated in 1994 and 1996 at a teaching hospital in Durban, South Africa. Antimicrob. Agents Chemother. 45:2001;88-95.
14. Shaw K.J., Rather P.N., Hare R.S., Miller G.H. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. Microbiol. Rev. 57:1993;138-163.