Induced tolerance to glutamate neurotoxicity through down-regulation of NR2 subunits of N-methyl-D-aspartate receptors in cultured rat striatal neurons

Journal of Neuroscience Research

Volumn 88, Issue 10, 2010, Pages 2177-2187

  Kambe, Yuki ^a,b   Nakamichi, Noritaka ^a   Takarada, Takeshi ^a   Fukumori, Ryo ^a   Yoneda, Yukio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Down regulation; Neurotoxicity; NMDA receptor; Striatum; Tolerance

Indexed keywords

CALCIUM; CALPASTATIN; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2C; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT; CYSTEINE PROTEINASE INHIBITOR; GLYCOPROTEIN; MESSENGER RNA; N METHYLASPARTIC ACID; NR1 NMDA RECEPTOR;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; EMBRYO; HIPPOCAMPUS; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; DRUG EFFECTS; INTRACELLULAR SPACE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL; PHYSIOLOGY; TIME;

ANIMALS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CORPUS STRIATUM; CYSTEINE PROTEINASE INHIBITORS; GLUTAMIC ACID; GLYCOPROTEINS; HIPPOCAMPUS; INTRACELLULAR SPACE; MEMBRANE POTENTIAL, MITOCHONDRIAL; N-METHYLASPARTATE; NEURONS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; TIME FACTORS;

EID: 77953639157     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22388     Document Type: Article

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