Plasmodium falciparum isolates from Angola show the StctVMNT haplotype in the pfcrt gene

Malaria Journal

Volumn 9, Issue 1, 2010, Pages

  Gama, Bianca E ^a,b   Pereira Carvalho, Guilhermina A L ^a,b,c   Lutucuta Kosi, Florbela J I ^a,b,c   Almeida De Oliveira, Natália K ^a,b   Fortes, Filomeno ^c   Rosenthal, Philip J ^d   Daniel Ribeiro, Cláudio T ^a,b   De Fátima Ferreira Da Cruz, Maria ^a,b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^c National Institute for Health Research   (Angola)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; ANTIMALARIAL AGENT; CARRIER PROTEIN; CHLOROQUINE; MDR1 PROTEIN, PLASMODIUM FALCIPARUM; MULTIDRUG RESISTANCE PROTEIN; PFCRT PROTEIN, PLASMODIUM FALCIPARUM; PROTOZOAL PROTEIN;

AMINO ACID SEQUENCE; ANGOLA; ARTICLE; BLOOD SAMPLING; CODON; DNA SEQUENCE; FUNGAL GENE; FUNGUS ISOLATION; HAPLOTYPE; NONHUMAN; PFCRT GENE; PFMDR1 GENE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE; ADULT; CLASSIFICATION; DRUG EFFECT; DRUG RESISTANCE; FEMALE; GENE FREQUENCY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALARIA FALCIPARUM; MALE; METABOLISM; MUTATION; PREVALENCE;

ADULT; ANGOLA; ANTIMALARIALS; CHLOROQUINE; DRUG RESISTANCE; FEMALE; GENE FREQUENCY; HAPLOTYPES; HUMANS; MALARIA, FALCIPARUM; MALE; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; PROTOZOAN PROTEINS; SEQUENCE ANALYSIS, DNA; YOUNG ADULT;

EID: 77953638714     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-9-174     Document Type: Article

References (35)

1. World malaria report 2008. WHO, http://malaria.who.int/wmr2008/ malaria2008.pdf
2. What does it take to control malaria? B Walter M Walter, Ann Trop Med Parasitol 2007 101 657 672 10.1179/136485907X229013 18028727
3. Drug resistance in malaria. PB Bloland, http://www.who.int/csr/resources/ publications/drugresist/malaria.pdf
4. Roll Back Malaria campaign still has a long way to go. I Haivas, BMJ 2003 326 951 10.1136/bmj.326.7396.951/c 12727754
5. History, dynamics and public health importance of malaria parasite resistance. AO Talisuna P Bloland U D'Alessandro, Clin Microbiol Rev 2004 17 235 254 10.1128/CMR.17.1.235-254.2004 14726463
6. Mutations in the P. falciparum digestive vacuole transmembrane protein pfcrt and evidence for their role in chloroquine resistance. DA Fidock T Nomura AK Talley RA Cooper SM Dzekunov MT Ferdig LM Ursos AB Sidhu B Naude KW Deitsch XZ Su JC Wootton PD Roepe TE Wellems, Molecular Cell 2000 6 861 871 10.1016/S1097-2765(05)00077-8 11090624
7. pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective. RA Cooper CL Hartwig MT Ferdig, Acta Trop 2005 94 170 180 15866507
8. Monitoring the antimalarial drug resistance: making the most of the tools at hand. CV Plowe, J Exp Biol 2003 206 3745 3752 10.1242/jeb.00658 14506209
9. Contribution of the pfmdr1 gene to antimalarial drug-resistance. MT Duraisingh AF Cowman, Acta Trop 2005 94 181 190 15876420
10. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. JC Wootton X Feng MT Ferdig RA Cooper J Mu DI Baruch AJ Magill XZ Su, Nature 2002 418 320 333 10.1038/nature00813 12124623
11. Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America. RK Mehlotra H Fujioka PD Roepe O Janneh LM Ursos V Jacobs-Lorena DT McNamara MJ Bockarie JW Kazura DE Kyle DA Fidock PA Zimmerman, Proc Natl Acad Sci USA 2001 98 12689 12694 10.1073/pnas.221440898 11675500
12. Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT. S Dittrich M Alifrangis JM Stohrer V Thongpaseuth V Vanisaveth R Phetsouvanh S Phompida IF Khalil T Jelinek, Trop Med Int Health 2005 10 1267 1270
13. Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines. N Chen DW Wilson C Pasay D Bell LB Martin D Kyle Q Cheng, Antimicrob Agents Chemother 2005 49 2102 2105 10.1128/AAC.49.5.2102-2105.2005 15855538
14. Short report: polymorphisms in the chloroquine resistance transporter gene in Plasmodium falciparum isolates from Lombok, Indonesia. MC Huaman K Yoshinaga A Suryanatha N Suarsana H Kanbara, Am J Trop Med Hyg 2004 71 40 42 15238686
15. Quinoline resistance associated polymorphisms in the pfcrt, pfmdr1 and pfmrp genes of Plasmodium falciparum in Iran. J Ursing S Zakeri JP Gil A Björkman, Acta Trop 2006 97 352 356 10.1016/j.actatropica.2006.01.002 16490179
16. TYR no gene pfmdr1 em clones de uma amostra de Plasmodium falciparum da África Ocidental, resistente à cloroquina. L Pinheiro S Franco IS Adagu R Rosa VE Do Rosrio DC Warhurst, Acta Med Portug 2003 16 229 233
17. Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola. P Figueiredo C Benchimol D Lopes L Bernardino VE do Rosario L Varandas F Nogueira, Malar J 2008 7 236 10.1186/1475-2875-7-236 19014684
18. Republic of Angola, Ministry of, Health, National Program for Malaria Control, Plano estratégico nacional para o controlo da malária em Angola (2008-2012). Luanda 2007
19. Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area. BE Gama NK de Oliveira MG Zalis JM de Souza F Santos CT Daniel-Ribeiro F Ferreira-da-Cruz M de, Malar J 2009 8 156 10.1186/1475-2875-8-156 19602248
20. ChromaPipe: a pipeline for analysis, quality control and management for a DNA sequencing facility. TD Otto EA Vasconcellos LHF Gomes AS Moreira WM Degrave L Mendonça-Lima M Alves-Ferreira, Genet Mol Res 2008 7 861 871 10.4238/vol7-3X-Meeting04 18949705
21. Malaria diagnosis: standardization of a polymerase chain reaction for the detection of Plasmodium falciparum parasites in individuals with low-grade parasitemia. MG Zalis MF Ferreira-da-Cruz HC Balthazar-Guedes DM Banic W Alecrim JM Souza P Druilhe CT Daniel-Ribeiro, Parasitol Res 1996 82 612 616 10.1007/s004360050173 8875568
22. Real-time PCR assay for rapid detection and analysis of PfCRT haplotypes of chloroquine-resistant Plasmodium falciparum isolates from India. J Keen GA Farcas K Zhong S Yohanna MW Dunne KC Kain, J Clin Microbiol 2007 45 2889 2893 10.1128/JCM.02291-06 17609321
23. Pfcrt haplotypes and in vivo chloroquine response in Sundergarh district, Orissa, India. SS Pati S Mishra S Mohanty DN Mohapatra PK Sahu N Priyadarshi S Kumar SK Sharma PK Tyagi CE Chitnis BS Das, Trans R Soc Trop Med Hyg 2007 101 650 654 10.1016/j.trstmh.2007.01.008 17428514
24. The dynamics of drug resistance in Plasmodium falciparum. WH Wernsdorfer D Payne, Pharmacol Ther 1991 1 95 121 10.1016/0163-7258(91)90074-V
25. pfcrt Polymorphism and the spread of chloroquine resistance in Plasmodium falciparum populations across the Amazon Basin. PP Vieira MU Ferreira MG Alecrim WD Alecrim LH da Silva MM Sihuincha DA Joy J Mu XZ Su MG Zalis, J Infect Dis 2004 190 417 424 10.1086/422006 15216481
26. Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum. RK Mehlotra G Mattera MJ Bockarie JD Maguire JK Baird YD Sharma M Alifrangis G Dorsey PJ Rosenthal DJ Fryauff JW Kazura M Stoneking PA Zimmerman, Antimicrob Agents Chemother 2008 52 2212 2122 10.1128/AAC.00089-08 18411325
27. Pfcrt and pfmdr1 alleles associated with chloroquine resistance in Plasmodium falciparum from Guyana, South America. W Best Plummer LM Pinto Pereira CV Carrington, Mem Inst Oswaldo Cruz 2004 99 389 392 15322628
28. Polymorphism of the Plasmodium falciparum multidrug resistance and chloroquine resistance transporter genes and in vitro susceptibility to aminoquinolines in isolates from the Peruvian Amazon. MC Huaman N Roncal S Nakazawa TT Long L Gerena C Garcia L Solari AJ Magill H Kanbara, Am J Trop Med Hyg 2004 70 461 466 15155976
29. Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. M Alifrangis MB Dalgaard JP Lusingu LS Vestergaard T Staalsoe AT Jensen A Enevold AM Rønn IF Khalil DC Warhurst MM Lemnge TG Theander IC Bygbjerg, J Infect Dis 2006 193 1738 1741 10.1086/504269 16703518
30. Wide variation in microsatellite sequences within each Pfcrt mutant haplotype. S Vinayak P Mittra YD Sharma, Mol Biochem Parasitol 2006 147 101 108 10.1016/j.molbiopara.2006.01.013 16516311
31. Prevalence of pfcrt point mutations and level of chloroquine resistance in Plasmodium falciparum isolates from Africa. C Severini M Menegon AR Sannella MG Paglia P Narciso A Matteelli M Gulletta P Caramello F Canta MV Xayavong IN Moura NJ Pieniazek D Taramelli G Majori, Infect Genet Evol 2006 6 2602 2608 10.1016/j.meegid.2005.07.002 (Pubitemid 43785812)
32. Association of pfcrt but not pfmdr1 alleles with chloroquine resistance in Iranian isolates of Plasmodium falciparum. S Zakeri M Afsharpad T Kazemzadeh K Mehdizadeh A Shabani ND Djadid, Am J Trop Med Hyg 2008 78 633 640 18385361
33. In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda. SL Nsobya M Kiggundu S Nanyunja M Joloba B Greenhouse PJ Rosenthal, Antimicrob Agents Chemother 2010 54 1200 1206 10.1128/AAC.01412-09 20065051
34. Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine. DC Warhurst, Malar J 2003 2 31 10.1186/1475-2875-2-31 14599295
35. Resistance-mediating Plasmodium falciparum pfcrt and pfmdr1 alleles after treatment with artesunate-amodiaquine in Uganda. SL Nsobya C Dokomajilar M Joloba G Dorsey PJ Rosenthal, Antimicrob Agents Chemother 2007 51 3023 3025 10.1128/AAC.00012-07 17562798