A transgenic mouse for imaging caspase-dependent apoptosis within the skin

Journal of Investigative Dermatology

Volumn 130, Issue 7, 2010, Pages 1797-1806

  Khanna, Divya ^a   Hamilton, Christin A ^a   Bhojani, Mahaveer S ^a   Lee, Kuei C ^a   Dlugosz, Andrej ^b   Ross, Brian D ^a   Rehemtulla, Alnawaz ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CASPASE 3; ESTROGEN RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; MEASUREMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN; TUMOR XENOGRAFT;

EID: 77953614259     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.55     Document Type: Article

References (29)

1. Afford S, Randhawa S (2000) Apoptosis. Mol Pathol 53:55-63
2. Bhojani MS, Rossu BD, Rehemtulla A (2003) TNFSF10 and anti-tumor responses. Cancer Biol Ther 2:S71-8
3. Botchkareva NV, Ahluwalia G, Shander D (2006) Apoptosis in the hair follicle. J Invest Dermatol 126:258-264
4. Brash DE (1996) Cellular proofreading. Nat Med 2:525-526
5. Cerroni L, Kerl H (1994) Aberrant bcl-2 protein expression provides a possible mechanism of neoplastic cell growth in cutaneous basal-cell carcinoma. J Cutan Pathol 21:398-403
6. Chinnaiyan AM, Prasad U, Shankar S et al. (2000) Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci USA 97:1754-1759
7. Denecker G, Hoste E, Gilbert B et al. (2007) Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol 9:666-674
8. Fanidi A, Harrington EA, Evan GI (1992) Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 359:554-556
9. Hengartner MO (2000) The biochemistry of apoptosis. Nature 407:770-776
10. Kanter-Lewensohn L, Hedblad MA, Wejde J et al. (1997) Immunohistochem-ical markers for distinguishing Spitz nevi from malignant melanomas. Mod Pathol 10:917-920
11. Kaufmann SH, Gores GJ (2000) Apoptosis in cancer: cause and cure. Bioessays 22:1007-1017
12. Kroemer G (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3:614-620
13. Laxman B, Hall DE, Bhojani MS et al. (2002) Noninvasive real-time imaging of apoptosis. Proc Natl Acad Sci USA 99:16551-16555
14. Li G, Tron V, Ho V (1998) Induction of squamous cell carcinoma in p53-deficient mice after ultraviolet irradiation. J Invest Dermatol 110:72-75
15. Lippens S, Hoste E, Vandenabeele P et al. (2009) Cell death in the skin. Apoptosis 14:549-569
16. Loro L, Vintermyr OK, Johannessen AC (2005) Apoptosis in normal and diseased oral tissues. Oral Dis 11:274-287
17. Morales-Ducret CR, van de Rijn M, LeBrun DP et al. (1995) bcl-2 expression in primary malignancies of the skin. Arch Dermatol 131:909-912
18. Nicholson DW, Thornberry NA (2003) Apoptosis. Life and death decisions. Science 299:214-215
19. Norris DA, Middleton MH, Whang K et al. (1997) Human keratinocytes maintain reversible anti-apoptotic defenses in vivo and in vitro. Apoptosis 2:136-148
20. Pincelli C, Haake AR, Benassi L et al. (1997) Autocrine nerve growth factor protects human keratinocytes from apoptosis through its high affinity receptor (TRK): a role for BCL-2. J Invest Dermatol 109:757-764
21. Raj D, Brash DE, Grossman D (2006) Keratinocyte apoptosis in epidermal development and disease. J Invest Dermatol 126:243-257
22. Ramirez A, Bravo A, Jorcano JL et al. (1994) Sequences 5 of the bovine keratin 5 gene direct tissue-and cell-type-specific expression of a lacZ gene in the adult and during development. Differentiation 58:53-64
23. Rodriguez-Villanueva J, Colome MI, Brisbay S et al. (1995) The expression and localization of bcl-2 protein in normal skin and in non-melanoma skin cancers. Pathol Res Pract 191:391-398
24. Shi Y (2002) Apoptosome: the cellular engine for the activation of caspase-9. Structure 10:285-288
25. Strasser A, O'Connor L, Dixit VM (2000) Apoptosis signaling. Annu Rev Biochem 69:217-245
26. Tung CH, Zeng Q, Shah K et al. (2004) In vivo imaging of b-galactosidaseactivity using far red fluorescent switch. Cancer Res 64:1579-1583
27. Yaar M, Eller MS, DiBenedetto P et al. (1994) The trk family of receptors mediates nerve growth factor and neurotrophin-3 effects in melanocytes. J Clin Invest 94:1550-1562
28. Zhai S, Yaar M, Doyle SM et al. (1996) Nerve growth factor rescues pigment cells from ultraviolet-induced apoptosis by upregulating BCL-2 levels. Exp Cell Res 224:335-343
29. Ziegler A, Jonason AS, Leffell DJ et al. (1994) Sunburn and p53 in the onset of skin cancer. Nature 372:773-776