Metals in air pollution particles decrease whole-blood coagulation time

Inhalation Toxicology

Volumn 22, Issue 8, 2010, Pages 621-626

  Sangani, Rahul G ^a   Soukup, Joleen M ^a   Ghio, Andrew J ^a,b,c  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Air pollution; Iron; Metals; Particulate matter; Zinc

Indexed keywords

CITRIC ACID; COPPER; DEFEROXAMINE; EDETIC ACID; FERRIOXAMINE; IRON; METAL; NICKEL; SULFATE; VANADIUM; ZINC; AIR POLLUTANT; CHELATING AGENT; FERRIC ION; PARTICULATE MATTER; ZINC DERIVATIVE;

AIR POLLUTION; AMBIENT AIR; ARTICLE; BLOOD CLOTTING TIME; HUMAN; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; ADULT; AIR POLLUTANT; ATOMIC ABSORPTION SPECTROMETRY; BLOOD CLOTTING; DRUG EFFECTS; FEMALE; MALE; OSMOLARITY; SOLUBILITY; TOXICITY; YOUNG ADULT;

ADULT; AIR POLLUTANTS; BLOOD COAGULATION; CHELATING AGENTS; DEFEROXAMINE; FEMALE; FERRIC COMPOUNDS; HUMANS; MALE; METALS; OSMOLAR CONCENTRATION; PARTICULATE MATTER; SOLUBILITY; SPECTROPHOTOMETRY, ATOMIC; SULFATES; WHOLE BLOOD COAGULATION TIME; YOUNG ADULT; ZINC COMPOUNDS;

EID: 77953594907     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958371003599037     Document Type: Article

References (36)

1. Baccarelli A, Martinelli I, Zanobetti A, Grillo P, Hou L.F, Bertazzi PA, Mannucci PM, Schwartz J. 2008. Exposure to particulate air pollution and risk of deep vein thrombosis. Arch Intern Med 168:920-927.
2. Ball JC, Straccia AM, Young WC, Aust AE. 2000. The formation of reactive oxygen species catalyzed by neutral, aqueous extracts of NIST ambient particulate matter and diesel engine particles. J Air Waste Manage Assoc 50:1897-1903.
3. Cheney K, Gumbiner C, Benson B, Tenenbein M. 1995. Survival after a severe iron poisoning treated with intermittent infusions of deferoxamine. J Toxicol Clin Toxicol 33:61-66.
4. Day SM, Duquaine D, Mundada LV, Menon RG, Khan BV, Rajagopalan S, Fay WP. 2003. Chronic iron administration increases vascular oxidative stress and accelerates arterial thrombosis. Circulation 107: 2601-2606.
5. D'Ippoliti D, Forastiere F, Ancona C, Agabiti. N, Fusco D, Michelozzi P, Perucci CA. 2003. Air pollution and myocardial infarction in Rome: A case-crossover analysis. Epidemiology 14:528-535.
6. Eldor A, Rachmilewitz EA. 2002. The hypercoagulable state in thalassemia. Blood 99:36-43.
7. Gardner SY, Lehmann JR, Costa DL. 2000. Oil fly ash-induced elevation of plasma fibrinogen levels in rats. Toxicol Sci 56:175-180.
8. Ghio AJ, Stonehuerner J, McGee JK, Kinsey JS. 1999. Sulfate content correlates with iron concentrations in ambient air pollution particles. Inhal Toxicol 11:293-307.
9. Gilmour PS, Nyska A, Schladweiler MC, McGee JK, Wallenborn JG, Richards JH, Kodavanti UP. 2006. Cardiovascular and blood coagulative effects of pulmonary zinc exposure. Toxicol Appl Pharmacol 211:41-52.
10. Haidari M. Javadi E, Sanati A, Hajilooi M, Ghanbili J. 2001. Association of increased ferritin with premature coronary stenosis in men. Clin Chem 47:1666-1672.
11. Jacob DJ, Gottlieb EW, Prather MJ. 1989. Chemistry of a polluted cloudy boundary layer. J Geophys Res 94:12975-13002.
12. Loiseau C, Randriamahazaka HN, Nigretto JM. 1997. Influence of Zn2+ on the kinetic events that contribute to the 500-kDa dextran-sulfate-dependent activation of factor XII (Hageman factor). Eur J Biochem 246: 204-210.
13. Munger JW, Jacob DJ, Waldman JM, Hoffmann MR. 1983. Fogwater chemistry in an urban atmosphere. J Geophys Res 88:5109-5121.
14. Kiechl S, Willeit J, Egger G, Poewe W, Oberhollenzer F. 1997. Body iron stores and the risk of carotid atherosclerosis: Prospective results from the Bruneck study. Circulation 96:3300-3307.
15. Maeda H, Kishi T, Ikeda S. 1983. The precipitation of human fibrinogen by zinc chloride. Bull Chem Soc Jpn 56:1351-1356.
16. Mutlu GM, Green D, Bellmeyer A, Baker CM, Burgess Z, Rajamannan N, Christman JW, Foiles N, Kamp DW, Ghio AJ, Chandel NS, Dean DA, Sznajder JI, Budinger GR. 2007. Ambient particulate matter accelerates coagulation via an IL-6-dependent pathway. J Clin Invest 117:2952-2961.
17. Nemmar A, Hoet PHM, Dinsdale D, Vermylen J, Hoylaerts MF, Nemery B. 2003a. Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 107:1202-1208.
18. Nemmar A, Nemery B, Hoet PHM, Vermylen J, Hoylaerts MF. 2003b. Pulmonary inflammation and thrombogenicity caused by diesel particles in hamsters. Am J Respir Crit Care Med 168:1366-1372.
19. Penglis F, Michal F. 1969. The induction of blood platelet aggregation by divalent cations. Experientia 25:745-746.
20. Peters A, Dockery DW, Muller JE, Mittleman MA. 2001. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 103:2810-2815.
21. Peters A, von Klot S, Heier M, Trentinaglia I, Hörmann A, Wichmann HE, Löwel H. 2004. Cooperative Health Research in the Region of Augsburg Study Group. Exposure to traffic and the onset of myocardial infarction. N Engl J Med 351:1721-1730.
22. Praticó D, Pasin M, Barry O.P, Ghiselli A, Sabatino G, Iuliano L, FitzGerald GA, Violi F. 1999. Iron-dependent human platelet activation and hydroxyl radical formation: Involvement of protein kinase C. Circulation 99:3118-3124.
23. Pritchard RJ, Ghio AJ, Lehmann JR, Winsett DW, Tepper JS, Park P, Gilmour MI, Dreher KL, Costa DL. 1996. Oxidant generation and lung injury after particulate air pollution exposure increase with the concentrations of associated metals. Inhal Toxicol 8:457-477.
24. Ross MA, Long WF, Williamson FB. 1992. Inhibition by heparin of Fe(II)-catalysed free-radical peroxidation of linolenic acid. Biochem J 286:717-720.
25. Seftel HC. 1965. Reactions to intravenous iron dextran. Br Med J 1:657.
26. Sempos CT. 2002. Do body iron stores increase the risk of developing coronary heart disease? Am J Clin Nutr 76:501-503.
27. Sharma RP Flora SJ, Drown DB, Oberg SG. 1987. Persistence of vanadium compounds in lungs after intratracheal instillation in rats. Toxicol Ind Health 3:321-329.
28. Steven FS, Griffin MM, Brown BS, Hulley TP. 1982. Aggregation of fibrinogen molecules by metal ions. Int J Biol Macromol 4:367-369.
29. Tunali T, Sener G, Yarat A, Emekli N. 2005. Melatonin reduces oxidative damage to skin and normalizes blood coagulation in a rat model of thermal injury. Life Sci 76:1259-1265.
30. Waldman JM, Munger JW, Jacob DJ, Flagan RC, Morgan JJ, Hoffmann MR. 1982. Chemical composition of acid fog. Science 218:677-680.
31. Wallenborn JG, McGee JK, Schladweiler MC, Ledbetter AD, Kodavanti UP. 2007. Systemic translocation of particulate matter-associated met als following a single intratracheal instillation in rats. Toxicol Sci 98: 231-239.
32. Wallenborn JG, Kovalcik KD, McGee JK, Landis MS, Kodavanti UP. 2009. Systemic translocation of (70)zinc: Kinetics following intratracheal instillation in rats. Toxicol Appl Pharmacol 234:25-32.
33. Wellenius GA, Schwartz J, Mittleman MA. 2005. Air pollution and hospital admissions for ischemic and hemorrhagic stroke among Medicare beneficiaries. Stroke 36:2549-2553.
34. World Health Organization. 2002. World Health Report. Geneva, Switzerland: World Health Organization.
35. Xu L, Wang X. 2005. An optimized murine model of ferric-chloride induced arterial thrombosis for thrombosis research. Thromb Res 115:95-100.
36. Zheng P-S, Reis M, Sparling C, Lee DY, La Pierre DP, Wong CK, Deng Z, Kahai S, Wen J, Yang BB. 2006. Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1. J Biol Chem 281:8175-8182.