Mutation at Ser392 specifically sensitizes mutant p53H175 to mdm2-mediated degradation

Cell Cycle

Volumn 9, Issue 7, 2010, Pages 1390-1398

  Gillotin, Sébastien ^a   Yap, Damian ^a,b   Lu, Xin ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Mdm2; Mutant p53; p300; Proteasome degradation

Indexed keywords

POLYUBIQUITIN; PROTEIN MDM2; PROTEIN P300; PROTEIN P53; SERINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; GENE MUTATION; HALF LIFE TIME; HUMAN; HUMAN CELL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; UBIQUITINATION;

EID: 77953591790     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.7.11253     Document Type: Article

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