메뉴 건너뛰기




Volumn 17, Issue 2, 2010, Pages 317-328

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; LUCIFERASE; MESSENGER RNA;

EID: 77953586698     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1677/ERC-09-0016     Document Type: Article
Times cited : (34)

References (52)
  • 5
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
    • Chu IM, Hengst L & Slingerland JM 2008 The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nature Reviews. Cancer 8 253-267.
    • (2008) Nature Reviews. Cancer , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 12
    • 3242710214 scopus 로고    scopus 로고
    • A single-nucleotide polymorphism in the human p27kip1 gene (-838CO>A) affects basal promoter activity and the risk of myocardial infarction
    • Gonzalez P, Diez-Juan A, Coto E, Alvarez V, Reguero JR, Batalla A & Andres V 2004 A single-nucleotide polymorphism in the human p27kip1 gene (-838CO>A) affects basal promoter activity and the risk of myocardial infarction. BMC Biology 2 5.
    • (2004) BMC Biology , vol.2 , pp. 5
    • Gonzalez, P.1    Diez-Juan, A.2    Coto, E.3    Alvarez, V.4    Reguero, J.R.5    Batalla, A.6    Andres, V.7
  • 13
    • 0026600358 scopus 로고
    • TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas
    • Greco A, Pierotti MA, Bongarzone I, Pagliardini S, Lanzi C & Della Porta G 1992 TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas. Oncogene 7 237-242.
    • (1992) Oncogene , vol.7 , pp. 237-242
    • Greco, A.1    Pierotti, M.A.2    Bongarzone, I.3    Pagliardini, S.4    Lanzi, C.5    Della Porta, G.6
  • 14
    • 0029670477 scopus 로고    scopus 로고
    • Translational control of p27Kip1 accumulation during the cell cycle
    • Hengst L & Reed SI 1996 Translational control of p27Kip1 accumulation during the cell cycle. Science 271 1861-1864. (Pubitemid 3040861)
    • (1996) Science , vol.271 , Issue.5257 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 15
    • 0034736585 scopus 로고    scopus 로고
    • Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control
    • Hilger-Eversheim K, Moser M, Schorle H & Buettner R 2000 Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control. Gene 260 1-12.
    • (2000) Gene , vol.260 , pp. 1-12
    • Hilger-Eversheim, K.1    Moser, M.2    Schorle, H.3    Buettner, R.4
  • 18
  • 22
    • 33645307434 scopus 로고    scopus 로고
    • Pathogenetic mechanisms in thyroid follicular-cell neoplasia
    • Kondo T, Ezzat S & Asa SL 2006 Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nature Reviews. Cancer 6 292-306.
    • (2006) Nature Reviews. Cancer , vol.6 , pp. 292-306
    • Kondo, T.1    Ezzat, S.2    Asa, S.L.3
  • 23
    • 35348875998 scopus 로고    scopus 로고
    • p27: Tumor suppressor and oncogene...?
    • Kossatz U & Malek NP 2007 p27: tumor suppressor and oncogene...? Cell Research 17 832-833.
    • (2007) Cell Research , vol.17 , pp. 832-833
    • Kossatz, U.1    Malek, N.P.2
  • 24
    • 38549158538 scopus 로고    scopus 로고
    • F-SNP: Computationally predicted functional SNPs for disease association studies
    • Lee PH & Shatkay H 2008 F-SNP: computationally predicted functional SNPs for disease association studies. Nucleic Acids Research 36 D820-D824.
    • (2008) Nucleic Acids Research , vol.36
    • Lee, P.H.1    Shatkay, H.2
  • 25
    • 3042631181 scopus 로고    scopus 로고
    • Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinoma
    • DOI 10.1158/1078-0432.CCR-04-0089
    • Li G, Sturgis EM, Wang LE, Chamberlain RM, Spitz MR, El-Naggar AK, Hong WK & Wei Q 2004 Association between the V109G polymorphism of the p27 gene and the risk and progression of oral squamous cell carcinoma. Clinical Cancer Research 10 3996-4002. (Pubitemid 38812473)
    • (2004) Clinical Cancer Research , vol.10 , Issue.12 I , pp. 3996-4002
    • Li, G.1    Sturgis, E.M.2    Wang, L.-E.3    Chamberlain, R.M.4    Spitz, M.R.5    El-Naggar, A.K.6    Hong, W.K.7    Wei, Q.8
  • 26
    • 34547235748 scopus 로고    scopus 로고
    • Mutational analysis of p27 (CDKN1B) and p18 (CDKN2C) in sporadic pancreatic endocrine tumors argues against tumor-suppressor function
    • Lindberg D, Akerstrom G & Westin G 2007 Mutational analysis of p27 (CDKN1B) and p18 (CDKN2C) in sporadic pancreatic endocrine tumors argues against tumor-suppressor function. Neoplasia 9 533-535.
    • (2007) Neoplasia , vol.9 , pp. 533-535
    • Lindberg, D.1    Akerstrom, G.2    Westin, G.3
  • 27
    • 22244468048 scopus 로고    scopus 로고
    • Regulation of expression by promoters versus internal ribosome entry site in the 50′-untranslated sequence of the human cyclin-dependent kinase inhibitor p27kip1
    • Liu Z, Dong Z, Han B, Yang Y, Liu Y & Zhang JT 2005 Regulation of expression by promoters versus internal ribosome entry site in the 50′-untranslated sequence of the human cyclin-dependent kinase inhibitor p27kip1. Nucleic Acids Research 33 3763-3771.
    • (2005) Nucleic Acids Research , vol.33 , pp. 3763-3771
    • Liu, Z.1    Dong, Z.2    Han, B.3    Yang, Y.4    Liu, Y.5    Zhang, J.T.6
  • 28
    • 49249127826 scopus 로고    scopus 로고
    • Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers
    • Liu Z, Hou P, Ji M, Guan H, Studeman K, Jensen K, Vasko V, El-Naggar AK & Xing M 2008 Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers. Journal of Clinical Endocrinology and Metabolism 93 3106-3116.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 3106-3116
    • Liu, Z.1    Hou, P.2    Ji, M.3    Guan, H.4    Studeman, K.5    Jensen, K.6    Vasko, V.7    El-Naggar, A.K.8    Xing, M.9
  • 29
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ & Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 30
    • 0033864096 scopus 로고    scopus 로고
    • A U-rich element in the 50′ untranslated region is necessary for the translation of p27 mRNA
    • Millard SS, Vidal A, Markus M & Koff A 2000 A U-rich element in the 50′ untranslated region is necessary for the translation of p27 mRNA. Molecular and Cellular Biology 20 5947-5959.
    • (2000) Molecular and Cellular Biology , vol.20 , pp. 5947-5959
    • Millard, S.S.1    Vidal, A.2    Markus, M.3    Koff, A.4
  • 31
    • 3442890875 scopus 로고    scopus 로고
    • Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia
    • Min YH, Cheong JW, Kim JY, Eom JI, Lee ST, Hahn JS, Ko YW & Lee MH 2004 Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia. Cancer Research 64 5225-5231.
    • (2004) Cancer Research , vol.64 , pp. 5225-5231
    • Min, Y.H.1    Cheong, J.W.2    Kim, J.Y.3    Eom, J.I.4    Lee, S.T.5    Hahn, J.S.6    Ko, Y.W.7    Lee, M.H.8
  • 32
    • 0030756064 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human p27Kip1 gene promoter
    • Minami S, Ohtani-Fujita N, Igata E, Tamaki T & Sakai T 1997 Molecular cloning and characterization of the human p27Kip1 gene promoter. FEBS Letters 411 1-6.
    • (1997) FEBS Letters , vol.411 , pp. 1-6
    • Minami, S.1    Ohtani-Fujita, N.2    Igata, E.3    Tamaki, T.4    Sakai, T.5
  • 35
    • 34247501138 scopus 로고    scopus 로고
    • P27 V109G polymorphism is associated with lymph node metastases but not with increased risk of breast cancer
    • Naidu R, Har YC & Taib NA 2007 P27 V109G polymorphism is associated with lymph node metastases but not with increased risk of breast cancer. Journal of Experimental & Clinical Cancer Research 26 133-140. (Pubitemid 46650054)
    • (2007) Journal of Experimental and Clinical Cancer Research , vol.26 , Issue.1 , pp. 133-140
    • Naidu, R.1    Har, Y.C.2    Taib, N.A.M.3
  • 36
    • 0035986363 scopus 로고    scopus 로고
    • RET/PTC rearrangement in thyroid tumors
    • Nikiforov YE 2002 RET/PTC rearrangement in thyroid tumors. Endocrine Pathology 13 3-16.
    • (2002) Endocrine Pathology , vol.13 , pp. 3-16
    • Nikiforov, Y.E.1
  • 38
    • 0034129775 scopus 로고    scopus 로고
    • Medullary carcinoma of the thyroid
    • Randolph GW & Maniar D 2000 Medullary carcinoma of the thyroid. Cancer Control 7 253-261.
    • (2000) Cancer Control , vol.7 , pp. 253-261
    • Randolph, G.W.1    Maniar, D.2
  • 41
    • 21844431711 scopus 로고    scopus 로고
    • The regulation of S phase initiation by p27Kip1 in NIH3T3 cells
    • Sa G, Guo Y & Stacey DW 2005 The regulation of S phase initiation by p27Kip1 in NIH3T3 cells. Cell Cycle 4 618-627.
    • (2005) Cell Cycle , vol.4 , pp. 618-627
    • Sa, G.1    Guo, Y.2    Stacey, D.W.3
  • 43
  • 44
    • 0034092911 scopus 로고    scopus 로고
    • Regulation of the cdk inhibitor p27 and its deregulation in cancer
    • Slingerland J & Pagano M 2000 Regulation of the cdk inhibitor p27 and its deregulation in cancer. Journal of Cellular Physiology 183 10-17.
    • (2000) Journal of Cellular Physiology , vol.183 , pp. 10-17
    • Slingerland, J.1    Pagano, M.2
  • 47
    • 26944464295 scopus 로고    scopus 로고
    • Molecular analysis of the p27/kip1 gene in breast cancer
    • Tigli H, Buyru N & Dalay N 2005 Molecular analysis of the p27/kip1 gene in breast cancer. Molecular Diagnosis 9 17-21.
    • (2005) Molecular Diagnosis , vol.9 , pp. 17-21
    • Tigli, H.1    Buyru, N.2    Dalay, N.3
  • 48
    • 0042532260 scopus 로고    scopus 로고
    • Understanding p27(kip1) deregulation in cancer: Down-regulation or mislocalization
    • Viglietto G, Motti ML & Fusco A 2002 Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization. Cell Cycle 1 394-400.
    • (2002) Cell Cycle , vol.1 , pp. 394-400
    • Viglietto, G.1    Motti, M.L.2    Fusco, A.3
  • 50
    • 35348879174 scopus 로고    scopus 로고
    • Genetic variants in cell cycle control pathway confer susceptibility to lung cancer
    • Wang W, Spitz MR, Yang H, Lu C, Stewart DJ & Wu X 2007a Genetic variants in cell cycle control pathway confer susceptibility to lung cancer. Clinical Cancer Research 13 5974-5981.
    • (2007) Clinical Cancer Research , vol.13 , pp. 5974-5981
    • Wang, W.1    Spitz, M.R.2    Yang, H.3    Lu, C.4    Stewart, D.J.5    Wu, X.6
  • 52
    • 0031012251 scopus 로고    scopus 로고
    • AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression
    • Zeng YX, Somasundaram K & el-Deiry WS 1997 AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression. Nature Genetics 15 78-82.
    • (1997) Nature Genetics , vol.15 , pp. 78-82
    • Zeng, Y.X.1    Somasundaram, K.2    El-Deiry, W.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.