An intuitive safety factor for cardiac propagation

Biophysical Journal

Volumn 98, Issue 12, 2010, Pages

  Boyle, Patrick M ^a   Vigmond, Edward J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77953576235     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2010.03.018     Document Type: Article

References (13)

1. Delgado, C., B. Steinhaus, ..., J. Jalife. 1990. Directional differences in excitability and margin of safety for propagation in sheep ventricular epicardial muscle. Circ. Res. 67:97-110. (Pubitemid 20223731)
2. Leon, L. J., and F. A. Roberge. 1991. Directional characteristics of action potential propagation in cardiac muscle. A model study. Circ. Res. 69:378-395.
3. Shaw, R. M., and Y. Rudy. 1997. Ionic mechanisms of propagation, in cardiac tissue. Roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling. Circ. Res. 81:727-741.
4. Romero, L., B. Trénor, ..., J. M. Ferrero, Jr. 2009. The relative role of refractoriness and source-sink relationship in reentry generation, during simulated acute ischemia. Ann. Biomed. Eng. 37:1560-1571.
5. Aslanidi, O. V., P. Stewart, ..., H. Zhang. 2009. Optimal velocity and safety of discontinuous conduction through, the heterogeneous Purkinje-ventricular junction. Biophys. J. 97:20-39.
6. .DiFrancesco, D., and D. Noble. 1985. A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philos. Trans. R. Soc. Lond. B Biol. Sci. 307:353-398.
7. Wang, Y., and Y. Rudy. 2000. Action potential propagation, in inhomogeneous cardiac tissue: safety factor considerations and ionic mechanism. Am. J. Physiol. Heart Circ. Physiol. 278:H.1019-H1029. (Pubitemid 30235475)
8. Vigmond, E. J., R., Weber dos Santos, ..., G. Plank. 2008. Solvers for the cardiac bidomain equations. Prog. Biophys. Mol. Biol. 96:3-18.
9. Skouibine, K. B., N. A. Trayanova, and P. K. Moore. 1999. Anode/ cathode make and break phenomena in a model, of defibrillation, IEEE Trans. Biomed. Eng. 46:769-777.
10. Tranum-Jensen, J., A. A. Wilde, ..., M. J. Janse. 1991. Morphology of electrophysiologically identified junctions between Purkinje fibers and ventricular muscle in rabbit and pig hearts. Circ. Res. 69:429-437.
11. Vassalle, M., and C. O. Lee. 1984. The relationship among intracellular sodium activity, calcium, and strophanthidin inotropy in canine cardiac Purkinje fibers. J. Gen. Physiol. 83:287-307. (Pubitemid 14151409)
12. Oosthoek, P. W., S. Virágh, ..., A. F. Moorman. 1993. Immunohistochemical delineation of the conduction system. II; The atrioventricular node and Purkinje fibers. Circ. Res. 73:482-491.
13. ten Tusscher, K. H. W. J., and A. V. Panfilov. 2006. Alternans and spiral breakup in a human ventricular tissue model, Am. J. Physiol. Heart Circ. Physiol. 291:H1088-H1100.