KV4.2 channels tagged in the S1-S2 loop for alpha-bungarotoxin binding provide a new tool for studies of channel expression and localization

Channels

Volumn 4, Issue 2, 2010, Pages 115-123

  Moise, Leonard ^a,b,c   Liu, Jing ^a   Pryazhnikov, Evgeny ^d   Khiroug, Leonard ^d   Jeromin, Andreas ^e   Hawrot, Edward ^a  

^a BROWN UNIVERSITY   (United States)

^b EpiVax Inc   (United States)

^c UNIVERSITY OF RHODE ISLAND   (United States)

^d UNIVERSITY OF HELSINKI   (Finland)

^e Banyan Biomarkers   (United States)

Author keywords

Alpha bungarotoxin; Ion channel; KV4.2; Mutagenesis; S1 S2 loop; Trafficking

Indexed keywords

ALPHA BUNGAROTOXIN; CALSENILIN; SHAL POTASSIUM CHANNEL; AMPA RECEPTOR; BUNGAROTOXIN; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; HYBRID PROTEIN; KV CHANNEL INTERACTING PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL MEMBRANE; CONFORMATION; HIPPOCAMPUS; IN VIVO STUDY; NERVE CELL; NONHUMAN; WILD TYPE; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; EMBRYOLOGY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; HUMAN; KINETICS; MEMBRANE POTENTIAL; METABOLISM; PATCH CLAMP TECHNIQUE; PROTEIN CONFORMATION; PROTEIN TRANSPORT; RADIOASSAY; RAT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; BUNGAROTOXINS; CELL LINE; HIPPOCAMPUS; HUMANS; KINETICS; KV CHANNEL-INTERACTING PROTEINS; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; PROTEIN TRANSPORT; RADIOLIGAND ASSAY; RATS; RECEPTORS, AMPA; RECOMBINANT FUSION PROTEINS; SHAL POTASSIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 77953575222     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.4.2.10878     Document Type: Article

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