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Volumn 16, Issue 3, 2010, Pages 510-517

Thrombin generation and fibrinolysis in anti-factor IX treated blood and plasma spiked with factor VIII inhibitor bypassing activity or recombinant factor VIIa

Author keywords

APCC; Aptamer; Factor IXa inhibition; Fibrinolysis; RFVIIa; Thrombin generation

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; ALTEPLASE; APTAMER; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 9; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TISSUE PLASMINOGEN ACTIVATOR;

EID: 77953565614     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2009.02164.x     Document Type: Article
Times cited : (24)

References (39)
  • 1
    • 10244270631 scopus 로고    scopus 로고
    • The use of recombinant factor VIIa in the treatment of bleeding disorders
    • Roberts HR, Monroe DM, White GC. The use of recombinant factor VIIa in the treatment of bleeding disorders. Blood 2004, 104:3858-64.
    • (2004) Blood , vol.104 , pp. 3858-3864
    • Roberts, H.R.1    Monroe, D.M.2    White, G.C.3
  • 2
    • 0027302704 scopus 로고
    • The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor
    • ten Cate H, Bauer KA, Levi M. The activation of factor X and prothrombin by recombinant factor VIIa in vivo is mediated by tissue factor. J Clin Invest 1993, 92:1207-12.
    • (1993) J Clin Invest , vol.92 , pp. 1207-1212
    • ten Cate, H.1    Bauer, K.A.2    Levi, M.3
  • 3
    • 0032837605 scopus 로고    scopus 로고
    • Factor Xa and prothrombin: mechanism of action of FEIBA
    • Turecek PL, Varadi K, Gritsch H. Factor Xa and prothrombin: mechanism of action of FEIBA. Vox Sang 1999, 77(Suppl. 1):72-9.
    • (1999) Vox Sang , vol.77 , Issue.SUPPL. 1 , pp. 72-79
    • Turecek, P.L.1    Varadi, K.2    Gritsch, H.3
  • 4
    • 10744231994 scopus 로고    scopus 로고
    • Factor VIII inhibitor-bypassing agents act by inducing thrombin generation and can be monitored by a thrombin generation assay
    • Turecek PL, Varadi K, Keil B. Factor VIII inhibitor-bypassing agents act by inducing thrombin generation and can be monitored by a thrombin generation assay. Pathophysiol Haemost Thromb 2003, 33:16-22.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , pp. 16-22
    • Turecek, P.L.1    Varadi, K.2    Keil, B.3
  • 5
    • 13244262642 scopus 로고    scopus 로고
    • Comparative thrombotic event incidence after infusion of recombinant factor VIIa versus factor VIII inhibitor bypass activity
    • Aledort LM. Comparative thrombotic event incidence after infusion of recombinant factor VIIa versus factor VIII inhibitor bypass activity. J Thromb Haemost 2004, 2:1700-8.
    • (2004) J Thromb Haemost , vol.2 , pp. 1700-1708
    • Aledort, L.M.1
  • 6
    • 17144437423 scopus 로고    scopus 로고
    • Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors
    • Key NS, Aledort LM, Beardsley D. Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors. Thromb Haemost 1998, 80:912-8.
    • (1998) Thromb Haemost , vol.80 , pp. 912-918
    • Key, N.S.1    Aledort, L.M.2    Beardsley, D.3
  • 7
    • 0030837755 scopus 로고    scopus 로고
    • Multicenter retrospective study on the utilization of FEIBA in France in patients with factor VIII and factor IX inhibitors. French FEIBA Study Group. Factor Eight Bypassing Activity
    • Negrier C, Goudemand J, Sultan Y, Bertrand M, Rothschild C, Lauroua P. Multicenter retrospective study on the utilization of FEIBA in France in patients with factor VIII and factor IX inhibitors. French FEIBA Study Group. Factor Eight Bypassing Activity. Thromb Haemost 1997, 77:1113-9.
    • (1997) Thromb Haemost , vol.77 , pp. 1113-1119
    • Negrier, C.1    Goudemand, J.2    Sultan, Y.3    Bertrand, M.4    Rothschild, C.5    Lauroua, P.6
  • 8
    • 20144389671 scopus 로고    scopus 로고
    • Dose effect and efficacy of rFVIIa in the treatment of haemophilia patients with inhibitors: analysis from the Hemophilia and Thrombosis Research Society Registry
    • Parameswaran R, Shapiro AD, Gill JC, Kessler CM. Dose effect and efficacy of rFVIIa in the treatment of haemophilia patients with inhibitors: analysis from the Hemophilia and Thrombosis Research Society Registry. Haemophilia 2005, 11:100-6.
    • (2005) Haemophilia , vol.11 , pp. 100-106
    • Parameswaran, R.1    Shapiro, A.D.2    Gill, J.C.3    Kessler, C.M.4
  • 9
    • 33846185403 scopus 로고    scopus 로고
    • A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor: the FEIBA NovoSeven Comparative (FENOC) Study
    • Astermark J, Donfield SM, DiMichele DM. A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor: the FEIBA NovoSeven Comparative (FENOC) Study. Blood 2007, 109:546-51.
    • (2007) Blood , vol.109 , pp. 546-551
    • Astermark, J.1    Donfield, S.M.2    DiMichele, D.M.3
  • 10
    • 36348983304 scopus 로고    scopus 로고
    • Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A
    • Hvas AM, Sorensen HT, Norengaard L, Christiansen K, Ingerslev J, Sorensen B. Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A. J Thromb Haemost 2007, 5:2408-14.
    • (2007) J Thromb Haemost , vol.5 , pp. 2408-2414
    • Hvas, A.M.1    Sorensen, H.T.2    Norengaard, L.3    Christiansen, K.4    Ingerslev, J.5    Sorensen, B.6
  • 11
    • 0036090268 scopus 로고    scopus 로고
    • Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A
    • Lisman T, Mosnier LO, Lambert T. Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A. Blood 2002, 99:175-9.
    • (2002) Blood , vol.99 , pp. 175-179
    • Lisman, T.1    Mosnier, L.O.2    Lambert, T.3
  • 13
    • 66149185433 scopus 로고    scopus 로고
    • In-vitro evaluation of anti-factor IXa aptamer on thrombin generation, clotting time, and viscoelastometry
    • Tanaka KA, Szlam F, Rusconi CP, Levy JH. In-vitro evaluation of anti-factor IXa aptamer on thrombin generation, clotting time, and viscoelastometry. Thromb Haemost 2009, 101:827-33.
    • (2009) Thromb Haemost , vol.101 , pp. 827-833
    • Tanaka, K.A.1    Szlam, F.2    Rusconi, C.P.3    Levy, J.H.4
  • 14
    • 0037026484 scopus 로고    scopus 로고
    • RNA aptamers as reversible antagonists of coagulation factor IXa
    • Rusconi CP, Scardino E, Layzer J. RNA aptamers as reversible antagonists of coagulation factor IXa. Nature 2002, 419:90-4.
    • (2002) Nature , vol.419 , pp. 90-94
    • Rusconi, C.P.1    Scardino, E.2    Layzer, J.3
  • 15
    • 33845388596 scopus 로고    scopus 로고
    • First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity
    • Dyke CK, Steinhubl SR, Kleiman NS. First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. Circulation 2006, 114:2490-7.
    • (2006) Circulation , vol.114 , pp. 2490-2497
    • Dyke, C.K.1    Steinhubl, S.R.2    Kleiman, N.S.3
  • 16
    • 67649439010 scopus 로고    scopus 로고
    • Finding the optimal concentration range for fibrinogen replacement after severe haemodilution: an in vitro model
    • Bolliger D, Szlam F, Molinaro RJ, Rahe-Meyer N, Levy JH, Tanaka KA. Finding the optimal concentration range for fibrinogen replacement after severe haemodilution: an in vitro model. Br J Anaesth 2009, 102:793-9.
    • (2009) Br J Anaesth , vol.102 , pp. 793-799
    • Bolliger, D.1    Szlam, F.2    Molinaro, R.J.3    Rahe-Meyer, N.4    Levy, J.H.5    Tanaka, K.A.6
  • 18
    • 0242401773 scopus 로고    scopus 로고
    • Calibrated automated thrombin generation measurement in clotting plasma
    • Hemker HC, Giesen P, Al Dieri R. Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 2003, 33:4-15.
    • (2003) Pathophysiol Haemost Thromb , vol.33 , pp. 4-15
    • Hemker, H.C.1    Giesen, P.2    Al Dieri, R.3
  • 19
    • 34248512983 scopus 로고    scopus 로고
    • Severe factor X deficiency in a pair of siblings: clinical presentation, phenotypic and genotypic features, prenatal diagnosis and treatment
    • Ingerslev J, Herlin T, Sorensen B, Clausen N, Chu KC, High KA. Severe factor X deficiency in a pair of siblings: clinical presentation, phenotypic and genotypic features, prenatal diagnosis and treatment. Haemophilia 2007, 13:334-6.
    • (2007) Haemophilia , vol.13 , pp. 334-336
    • Ingerslev, J.1    Herlin, T.2    Sorensen, B.3    Clausen, N.4    Chu, K.C.5    High, K.A.6
  • 20
    • 47649108091 scopus 로고    scopus 로고
    • Thrombelastographic monitoring of recombinant factor VIIa in acquired haemophilia
    • Dehmel H, Werwitzke S, Trummer A, Ganser A, Tiede A. Thrombelastographic monitoring of recombinant factor VIIa in acquired haemophilia. Haemophilia 2008, 14:736-42.
    • (2008) Haemophilia , vol.14 , pp. 736-742
    • Dehmel, H.1    Werwitzke, S.2    Trummer, A.3    Ganser, A.4    Tiede, A.5
  • 21
    • 47649108640 scopus 로고    scopus 로고
    • Effects of factor VIII inhibitor bypassing activity (FEIBA), recombinant factor VIIa or both on thrombin generation in normal and haemophilia A plasma
    • Livnat T, Martinowitz U, Zivelin A, Seligsohn U. Effects of factor VIII inhibitor bypassing activity (FEIBA), recombinant factor VIIa or both on thrombin generation in normal and haemophilia A plasma. Haemophilia 2008, 14:782-6.
    • (2008) Haemophilia , vol.14 , pp. 782-786
    • Livnat, T.1    Martinowitz, U.2    Zivelin, A.3    Seligsohn, U.4
  • 22
    • 0035251820 scopus 로고    scopus 로고
    • Effect of activated prothrombin complex concentrate or recombinant factor VIIa on the bleeding time and thrombus formation during anticoagulation with a direct thrombin inhibitor
    • Elg M, Carlsson S, Gustafsson D. Effect of activated prothrombin complex concentrate or recombinant factor VIIa on the bleeding time and thrombus formation during anticoagulation with a direct thrombin inhibitor. Thromb Res 2001, 101:145-57.
    • (2001) Thromb Res , vol.101 , pp. 145-157
    • Elg, M.1    Carlsson, S.2    Gustafsson, D.3
  • 23
    • 39749191349 scopus 로고    scopus 로고
    • Antithrombin affects hemostatic response to recombinant activated factor VII in factor VIII deficient plasma
    • Szlam F, Taketomi T, Sheppard CA, Kempton CL, Levy JH, Tanaka KA. Antithrombin affects hemostatic response to recombinant activated factor VII in factor VIII deficient plasma. Anesth Analg 2008, 106:719-24.
    • (2008) Anesth Analg , vol.106 , pp. 719-724
    • Szlam, F.1    Taketomi, T.2    Sheppard, C.A.3    Kempton, C.L.4    Levy, J.H.5    Tanaka, K.A.6
  • 24
    • 0034048938 scopus 로고    scopus 로고
    • Coagulation-associated enhancement of fibrinolytic activity via a neutralization of PAI-1 activity
    • Urano T, Ihara H, Suzuki Y, Takada Y, Takada A. Coagulation-associated enhancement of fibrinolytic activity via a neutralization of PAI-1 activity. Semin Thromb Hemost 2000, 26:39-42.
    • (2000) Semin Thromb Hemost , vol.26 , pp. 39-42
    • Urano, T.1    Ihara, H.2    Suzuki, Y.3    Takada, Y.4    Takada, A.5
  • 25
    • 0031878755 scopus 로고    scopus 로고
    • Human thrombin and calcium bound factor Xa significantly shorten tPA-induced fibrin clot lysis time via neutralization of plasminogen activator inhibitor type 1 activity
    • Urano T, Nagai N, Matsuura M, Ihara H, Takada Y, Takada A. Human thrombin and calcium bound factor Xa significantly shorten tPA-induced fibrin clot lysis time via neutralization of plasminogen activator inhibitor type 1 activity. Thromb Haemost 1998, 80:161-6.
    • (1998) Thromb Haemost , vol.80 , pp. 161-166
    • Urano, T.1    Nagai, N.2    Matsuura, M.3    Ihara, H.4    Takada, Y.5    Takada, A.6
  • 26
    • 0018864494 scopus 로고
    • Cross-linking of alpha 2-plasmin inhibitor to fibrin by fibrin-stabilizing factor
    • Sakata Y, Aoki N. Cross-linking of alpha 2-plasmin inhibitor to fibrin by fibrin-stabilizing factor. J Clin Invest 1980, 65:290-7.
    • (1980) J Clin Invest , vol.65 , pp. 290-297
    • Sakata, Y.1    Aoki, N.2
  • 27
    • 0032538447 scopus 로고    scopus 로고
    • Human procarboxypeptidase U, or thrombin-activable fibrinolysis inhibitor, is a substrate for transglutaminases. Evidence for transglutaminase-catalyzed cross-linking to fibrin
    • Valnickova Z, Enghild JJ. Human procarboxypeptidase U, or thrombin-activable fibrinolysis inhibitor, is a substrate for transglutaminases. Evidence for transglutaminase-catalyzed cross-linking to fibrin. J Biol Chem 1998, 273:27220-4.
    • (1998) J Biol Chem , vol.273 , pp. 27220-27224
    • Valnickova, Z.1    Enghild, J.J.2
  • 28
    • 0036660207 scopus 로고    scopus 로고
    • Thrombin functions during tissue factor-induced blood coagulation
    • Brummel KE, Paradis SG, Butenas S, Mann KG. Thrombin functions during tissue factor-induced blood coagulation. Blood 2002, 100:148-52.
    • (2002) Blood , vol.100 , pp. 148-152
    • Brummel, K.E.1    Paradis, S.G.2    Butenas, S.3    Mann, K.G.4
  • 29
    • 0027515051 scopus 로고
    • Competition between plasminogen and tissue plasminogen activator for cellular binding sites
    • Felez J, Chanquia CJ, Fabregas P, Plow EF, Miles LA. Competition between plasminogen and tissue plasminogen activator for cellular binding sites. Blood 1993, 82:2433-41.
    • (1993) Blood , vol.82 , pp. 2433-2441
    • Felez, J.1    Chanquia, C.J.2    Fabregas, P.3    Plow, E.F.4    Miles, L.A.5
  • 30
    • 33750222459 scopus 로고    scopus 로고
    • Regulation of fibrinolysis by thrombin activatable fibrinolysis inhibitor, an unstable carboxypeptidase B that unites the pathways of coagulation and fibrinolysis
    • Mosnier LO, Bouma BN. Regulation of fibrinolysis by thrombin activatable fibrinolysis inhibitor, an unstable carboxypeptidase B that unites the pathways of coagulation and fibrinolysis. Arterioscler Thromb Vasc Biol 2006, 26:2445-53.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2445-2453
    • Mosnier, L.O.1    Bouma, B.N.2
  • 31
    • 0030742896 scopus 로고    scopus 로고
    • Thrombin, thrombomodulin and TAFI in the molecular link between coagulation and fibrinolysis
    • Nesheim M, Wang W, Boffa M, Nagashima M, Morser J, Bajzar L. Thrombin, thrombomodulin and TAFI in the molecular link between coagulation and fibrinolysis. Thromb Haemost 1997, 78:386-91.
    • (1997) Thromb Haemost , vol.78 , pp. 386-391
    • Nesheim, M.1    Wang, W.2    Boffa, M.3    Nagashima, M.4    Morser, J.5    Bajzar, L.6
  • 32
    • 33847054740 scopus 로고    scopus 로고
    • A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia
    • Allen GA, Persson E, Campbell RA, Ezban M, Hedner U, Wolberg AS. A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia. Arterioscler Thromb Vasc Biol 2007, 27:683-9.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 683-689
    • Allen, G.A.1    Persson, E.2    Campbell, R.A.3    Ezban, M.4    Hedner, U.5    Wolberg, A.S.6
  • 33
    • 0842311466 scopus 로고    scopus 로고
    • Enhanced in vitro procoagulant and antifibrinolytic potential of superactive variants of recombinant factor VIIa in severe hemophilia A
    • Lisman T, de Groot PG, Lambert T, Rojkjaer R, Persson E. Enhanced in vitro procoagulant and antifibrinolytic potential of superactive variants of recombinant factor VIIa in severe hemophilia A. J Thromb Haemost 2003, 1:2175-8.
    • (2003) J Thromb Haemost , vol.1 , pp. 2175-2178
    • Lisman, T.1    de Groot, P.G.2    Lambert, T.3    Rojkjaer, R.4    Persson, E.5
  • 34
    • 33947494621 scopus 로고    scopus 로고
    • Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A
    • Sorensen B, Persson E, Ingerslev J. Factor VIIa analogue (V158D/E296V/M298Q-FVIIa) normalises clot formation in whole blood from patients with severe haemophilia A. Br J Haematol 2007, 137:158-65.
    • (2007) Br J Haematol , vol.137 , pp. 158-165
    • Sorensen, B.1    Persson, E.2    Ingerslev, J.3
  • 36
    • 34147136729 scopus 로고    scopus 로고
    • TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots
    • Mutch NJ, Thomas L, Moore NR, Lisiak KM, Booth NA. TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots. J Thromb Haemost 2007, 5:812-7.
    • (2007) J Thromb Haemost , vol.5 , pp. 812-817
    • Mutch, N.J.1    Thomas, L.2    Moore, N.R.3    Lisiak, K.M.4    Booth, N.A.5
  • 37
    • 65349153112 scopus 로고    scopus 로고
    • The role of tissue factor and factor VIIa in hemostasis
    • Mackman N. The role of tissue factor and factor VIIa in hemostasis. Anesth Analg 2009, 108:1447-52.
    • (2009) Anesth Analg , vol.108 , pp. 1447-1452
    • Mackman, N.1
  • 38
    • 65349153111 scopus 로고    scopus 로고
    • Blood coagulation: hemostasis and thrombin regulation
    • Tanaka KA, Key NS, Levy JH. Blood coagulation: hemostasis and thrombin regulation. Anesth Analg 2009, 108:1433-46.
    • (2009) Anesth Analg , vol.108 , pp. 1433-1446
    • Tanaka, K.A.1    Key, N.S.2    Levy, J.H.3
  • 39
    • 0036304070 scopus 로고    scopus 로고
    • Possible synergy between recombinant factor VIIa and prothrombin complex concentrate in hemophilia therapy
    • Key NS, Christie B, Henderson N, Nelsestuen GL. Possible synergy between recombinant factor VIIa and prothrombin complex concentrate in hemophilia therapy. Thromb Haemost 2002, 88:60-5.
    • (2002) Thromb Haemost , vol.88 , pp. 60-65
    • Key, N.S.1    Christie, B.2    Henderson, N.3    Nelsestuen, G.L.4


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