Specific ligands as pharmacological chaperones: The transport of misfolded G-protein coupled receptors to the cell surface

IUBMB Life

Volumn 62, Issue 6, 2010, Pages 453-459

  Nakamura, Motonao ^a,b   Yasuda, Daisuke ^a   Hirota, Nobuaki ^a   Shimizu, Takao ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Endoplasmic reticulum; Endoplasmic reticulum associated degradation; G protein coupled receptor; Lipid ligand; Pharmacological chaperone

Indexed keywords

AMINO ACID DERIVATIVE; CHAPERONE; G PROTEIN COUPLED RECEPTOR;

CELL MIGRATION; CELL SURFACE; ENDOPLASMIC RETICULUM; GENE MUTATION; HUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN TRANSPORT; QUALITY CONTROL; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; CHEMISTRY, PHARMACEUTICAL; HUMANS; LIGANDS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 77953558583     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.344     Document Type: Review

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