Testis dysfunction by isoproterenol is mediated by upregulating endothelin receptor A, leptin and protein kinase Ce{open} and is attenuated by an endothelin receptor antagonist CPU0213

Reproductive Toxicology

Volumn 29, Issue 4, 2010, Pages 421-426

  Cheng, Yu Si ^a   Dai, De Zai ^a   Dai, Yin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

ETA; Isoproterenol; Leptin; Male hypogonadism; PPKCe open

Indexed keywords

ACID PHOSPHATASE; CPU 0213; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; FOLLITROPIN; GAMMA GLUTAMYLTRANSFERASE; ISOPRENALINE; LACTATE DEHYDROGENASE; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; PROTEIN KINASE C EPSILON; SUCCINATE DEHYDROGENASE; TESTOSTERONE; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CPU0213; PYRAZOLE DERIVATIVE;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FEMALE; FOLLITROPIN BLOOD LEVEL; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; NONHUMAN; RAT; SEMINIFEROUS TUBULE; SPRAGUE DAWLEY RAT; TESTIS INJURY; TESTOSTERONE BLOOD LEVEL; UPREGULATION; ANIMAL; BLOOD; DRUG COMBINATION; DRUG EFFECTS; GENE EXPRESSION; GENETICS; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBCUTANEOUS DRUG ADMINISTRATION; TESTIS; TOXICITY; WESTERN BLOTTING;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BLOTTING, WESTERN; DRUG THERAPY, COMBINATION; FOLLICLE STIMULATING HORMONE; GENE EXPRESSION; INJECTIONS, SUBCUTANEOUS; ISOPROTERENOL; LEPTIN; MALE; PHOSPHORYLATION; PROTEIN KINASE C-EPSILON; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEMINIFEROUS TUBULES; TESTIS; TESTOSTERONE; UP-REGULATION;

RATTUS;

EID: 77953545295     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2010.03.001     Document Type: Article

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