Upregulated endothelin system in diabetic vascular dysfunction and early retinopathy is reversed by CPU0213 and total triterpene acids from Fructus Corni

Clinical and Experimental Pharmacology and Physiology

Volumn 34, Issue 12, 2007, Pages 1228-1233

  Su, Wei ^a   Dai, De Zai ^a   Liu, Hao Ran ^a   Na, Tao ^a   Dai, Yin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aminoguanidine; Blood vessels; CPU0213; Diabetes; Endothelin pathway; Endothelin receptor antagonist; Rats; Retinopathy; Total triterpene acid; Vasculopathy

Indexed keywords

ACETYLCHOLINE; AMINOGUANIDINE; CPU 0213; ENDOTHELIN; ENDOTHELIN RECEPTOR ANTAGONIST; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; FRUIT; GENETIC TRANSCRIPTION; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RETINOPATHY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THORACIC AORTA; UPREGULATION; VASCULAR DISEASE; VASODILATATION;

ANIMALS; AORTA, THORACIC; ASPARTIC ENDOPEPTIDASES; CORNUS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ENDOTHELIN-1; GUANIDINES; MALE; METALLOENDOPEPTIDASES; NITRIC OXIDE SYNTHASE TYPE II; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RETINA; RNA, MESSENGER; THORACIC ARTERIES; TRITERPENES; UP-REGULATION; VASODILATION;

EID: 35548977983     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2007.04698.x     Document Type: Article

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