-
1
-
-
0029999787
-
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
-
Alonso A.C., Grundke-Iqbal I., Iqbal K. Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nat. Med. 1996, 2:783-787.
-
(1996)
Nat. Med.
, vol.2
, pp. 783-787
-
-
Alonso, A.C.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
2
-
-
1642289188
-
Role of tau protein in both physiological and pathological conditions
-
Avila J., Lucas J.J., Perez M., Hernandez F. Role of tau protein in both physiological and pathological conditions. Physiol. Rev. 2004, 84:361-384.
-
(2004)
Physiol. Rev.
, vol.84
, pp. 361-384
-
-
Avila, J.1
Lucas, J.J.2
Perez, M.3
Hernandez, F.4
-
3
-
-
22844445324
-
Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro
-
Barghorn S., Biernat J., Mandelkow E. Purification of recombinant tau protein and preparation of Alzheimer-paired helical filaments in vitro. Methods Mol. Biol. 2005, 299:35-51.
-
(2005)
Methods Mol. Biol.
, vol.299
, pp. 35-51
-
-
Barghorn, S.1
Biernat, J.2
Mandelkow, E.3
-
5
-
-
10944241542
-
Tau alteration and neuronal degeneration in tauopathies: mechanisms and models
-
Brandt R., Hundelt M., Shahani N. Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. Biochim. Biophys. Acta 2005, 1739:331-354.
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 331-354
-
-
Brandt, R.1
Hundelt, M.2
Shahani, N.3
-
6
-
-
0028380369
-
Superhelical density of goat mitochondrial DNA: fluorescent studies
-
Chatterjee B., Rao G.R.K. Superhelical density of goat mitochondrial DNA: fluorescent studies. Indian J. Biochem. Biophys. 1994, 31:77-79.
-
(1994)
Indian J. Biochem. Biophys.
, vol.31
, pp. 77-79
-
-
Chatterjee, B.1
Rao, G.R.K.2
-
7
-
-
49149109927
-
Is tau aggregation toxic or protective?
-
Congdon E.E., Duff K.E. Is tau aggregation toxic or protective?. J. Alzheimers Dis. 2008, 14:453-457.
-
(2008)
J. Alzheimers Dis.
, vol.14
, pp. 453-457
-
-
Congdon, E.E.1
Duff, K.E.2
-
9
-
-
0019224686
-
Effects of DNA on microtubule assembly
-
Corces V.G., Manso R., De La Torre J., Avila J., Nasr A., Wiche G. Effects of DNA on microtubule assembly. Eur. J. Biochem. 1980, 105:7-16.
-
(1980)
Eur. J. Biochem.
, vol.105
, pp. 7-16
-
-
Corces, V.G.1
Manso, R.2
De La Torre, J.3
Avila, J.4
Nasr, A.5
Wiche, G.6
-
10
-
-
0033544963
-
The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation
-
Davis P.K., Johnson G.V. The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation. J. Biol. Chem. 1999, 274:35686-35692.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35686-35692
-
-
Davis, P.K.1
Johnson, G.V.2
-
11
-
-
49149131122
-
Tau pathology and neurodegeneration: an obvious but misunderstood link
-
Delacourte A. Tau pathology and neurodegeneration: an obvious but misunderstood link. J. Alzheimers Dis. 2008, 14:437-440.
-
(2008)
J. Alzheimers Dis.
, vol.14
, pp. 437-440
-
-
Delacourte, A.1
-
12
-
-
0027058857
-
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau
-
Drechsel D.N., Hyman A.A., Cobb M.H., Kirschner M.W. Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol. Biol. Cell. 1992, 3:1141-1154.
-
(1992)
Mol. Biol. Cell.
, vol.3
, pp. 1141-1154
-
-
Drechsel, D.N.1
Hyman, A.A.2
Cobb, M.H.3
Kirschner, M.W.4
-
13
-
-
0037111833
-
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease
-
Fath T., Eidenmüller J., Brandt R. Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease. J. Neurosci. 2002, 22:9733-9741.
-
(2002)
J. Neurosci.
, vol.22
, pp. 9733-9741
-
-
Fath, T.1
Eidenmüller, J.2
Brandt, R.3
-
14
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert M., Spillantini M.G., Jakes R., Rutherford D., Crowther R.A. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 1989, 3:519-526.
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
15
-
-
0344653664
-
Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease
-
Gómez-Isla T., Hollister R., West H., Mui S., Growdon J.H., Petersen R.C., Parisi J.E., Hyman B.T. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 1997, 41:17-24.
-
(1997)
Ann. Neurol.
, vol.41
, pp. 17-24
-
-
Gómez-Isla, T.1
Hollister, R.2
West, H.3
Mui, S.4
Growdon, J.H.5
Petersen, R.C.6
Parisi, J.E.7
Hyman, B.T.8
-
16
-
-
33747862732
-
Extracellular tau is toxic to neuronal cells
-
Gómez-Ramos A., Díaz-Hernández M., Cuadros R., Hernández F., Avila J. Extracellular tau is toxic to neuronal cells. FEBS Lett. 2006, 580:4842-4850.
-
(2006)
FEBS Lett.
, vol.580
, pp. 4842-4850
-
-
Gómez-Ramos, A.1
Díaz-Hernández, M.2
Cuadros, R.3
Hernández, F.4
Avila, J.5
-
17
-
-
0019315381
-
Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein-nucleic acid interactions
-
González R.G., Haxo R.S., Schleich T. Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein-nucleic acid interactions. Biochemistry 1980, 19:4299-4303.
-
(1980)
Biochemistry
, vol.19
, pp. 4299-4303
-
-
González, R.G.1
Haxo, R.S.2
Schleich, T.3
-
18
-
-
0017874455
-
Dehydrated circular DNA: circular dichroism of molecules in ethanolic solutions
-
Gray D.M., Taylor T.N., Lang D. Dehydrated circular DNA: circular dichroism of molecules in ethanolic solutions. Biopolymers 1978, 17:145-157.
-
(1978)
Biopolymers
, vol.17
, pp. 145-157
-
-
Gray, D.M.1
Taylor, T.N.2
Lang, D.3
-
19
-
-
0029161154
-
Localization and in situ phosphorylation state of nuclear tau
-
Greenwood J.A., Johnson G.V. Localization and in situ phosphorylation state of nuclear tau. Exp. Cell. Res. 1995, 220:332-337.
-
(1995)
Exp. Cell. Res.
, vol.220
, pp. 332-337
-
-
Greenwood, J.A.1
Johnson, G.V.2
-
20
-
-
0033554182
-
Regulation of expression, phosphorylation and biological activity of tau during differentiation in SY5Y cells
-
Haque N., Tanaka T., Iqbal K., Grundke-Iqbal I. Regulation of expression, phosphorylation and biological activity of tau during differentiation in SY5Y cells. Brain Res. 1999, 838:69-77.
-
(1999)
Brain Res.
, vol.838
, pp. 69-77
-
-
Haque, N.1
Tanaka, T.2
Iqbal, K.3
Grundke-Iqbal, I.4
-
21
-
-
0028301455
-
Altered microtubule organization in small-calibre axons of mice lacking tau protein
-
Harada A., Oguchi K., Okabe S., Kuno J., Terada S., Ohshima T., Sato-Yoshitake R., Takei Y., Noda T., Hirokawa N. Altered microtubule organization in small-calibre axons of mice lacking tau protein. Nature 1994, 369:488-491.
-
(1994)
Nature
, vol.369
, pp. 488-491
-
-
Harada, A.1
Oguchi, K.2
Okabe, S.3
Kuno, J.4
Terada, S.5
Ohshima, T.6
Sato-Yoshitake, R.7
Takei, Y.8
Noda, T.9
Hirokawa, N.10
-
22
-
-
0012505469
-
Tau could protect DNA double helix structure
-
Hua Q., He R.Q. Tau could protect DNA double helix structure. Biochim. Biophys. Acta 2003, 1645:205-211.
-
(2003)
Biochim. Biophys. Acta
, vol.1645
, pp. 205-211
-
-
Hua, Q.1
He, R.Q.2
-
23
-
-
0037299017
-
Microtubule associated protein tau binds to double-stranded but not single-stranded DNA
-
Hua Q., He R.Q., Haque N., Qu M.H., del Carmen Alonso A., Grundke-Iqbal I., Iqbal K. Microtubule associated protein tau binds to double-stranded but not single-stranded DNA. Cell. Mol. Life Sci. 2003, 60:413-421.
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 413-421
-
-
Hua, Q.1
He, R.Q.2
Haque, N.3
Qu, M.H.4
del Carmen Alonso, A.5
Grundke-Iqbal, I.6
Iqbal, K.7
-
24
-
-
0033969771
-
Muscle weakness, hyperactivity and impairment in fear conditioning in tau-deficient mice
-
Ikegami S., Harada A., Hirokawa N. Muscle weakness, hyperactivity and impairment in fear conditioning in tau-deficient mice. Neurosci. Lett. 2000, 279:129-132.
-
(2000)
Neurosci. Lett.
, vol.279
, pp. 129-132
-
-
Ikegami, S.1
Harada, A.2
Hirokawa, N.3
-
25
-
-
67349142329
-
Mechanisms of tau-induced neurodegeneration
-
Iqbal K., Liu F., Gong C.X., Alonso Adel C., Grundke-Iqbal I. Mechanisms of tau-induced neurodegeneration. Acta Neuropathol. 2009, 118:53-69.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 53-69
-
-
Iqbal, K.1
Liu, F.2
Gong, C.X.3
Alonso Adel, C.4
Grundke-Iqbal, I.5
-
26
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson G.R., Wiedau-Pazos M., Sang T.K., Wagle N., Brown C.A., Massachi S., Geschwind D.H. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 2002, 34:509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
27
-
-
14244251724
-
Tau protein binds single-stranded DNA sequence specifically-the proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures
-
Krylova S.M., Musheev M., Nutiu R., Li Y., Lee G., Krylov S.N. Tau protein binds single-stranded DNA sequence specifically-the proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures. FEBS Lett. 2005, 579:1371-1375.
-
(2005)
FEBS Lett.
, vol.579
, pp. 1371-1375
-
-
Krylova, S.M.1
Musheev, M.2
Nutiu, R.3
Li, Y.4
Lee, G.5
Krylov, S.N.6
-
28
-
-
17044439021
-
Alzheimer's disease: abeta, tau and synaptic dysfunction
-
LaFerla F.M., Oddo S. Alzheimer's disease: abeta, tau and synaptic dysfunction. Trends Mol. Med. 2005, 11:170-176.
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 170-176
-
-
LaFerla, F.M.1
Oddo, S.2
-
29
-
-
0025096279
-
Identification of nuclear tau isoforms in human neuroblastoma cells
-
Loomis P.A., Howard T.H., Castleberry R.P., Binder L.I. Identification of nuclear tau isoforms in human neuroblastoma cells. Proc. Natl. Acad. Sci. U.S.A. 1990, 87:8422-8426.
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 8422-8426
-
-
Loomis, P.A.1
Howard, T.H.2
Castleberry, R.P.3
Binder, L.I.4
-
30
-
-
0027453202
-
Functional studies of Alzheimer's disease tau protein
-
Lu Q., Wood J.G. Functional studies of Alzheimer's disease tau protein. J. Neurosci. 1993, 13:508-515.
-
(1993)
J. Neurosci.
, vol.13
, pp. 508-515
-
-
Lu, Q.1
Wood, J.G.2
-
31
-
-
0033540064
-
Alzheimer's disease. The tangled tale of tau
-
Mandelkow E. Alzheimer's disease. The tangled tale of tau. Nature 1999, 402:588-589.
-
(1999)
Nature
, vol.402
, pp. 588-589
-
-
Mandelkow, E.1
-
32
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow E.M., Stamer K., Vogel R., Thies E., Mandelkow E. Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol. Aging 2003, 24:1079-1085.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 1079-1085
-
-
Mandelkow, E.M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
33
-
-
0028897910
-
Nuclear tau immunoreactivity in presenile dementia with motor neuron disease: a case report
-
Papasozomenos S.C. Nuclear tau immunoreactivity in presenile dementia with motor neuron disease: a case report. Clin. Neuropathol. 1995, 14:100-104.
-
(1995)
Clin. Neuropathol.
, vol.14
, pp. 100-104
-
-
Papasozomenos, S.C.1
-
34
-
-
11244331892
-
Neuronal tau induces DNA conformational changes observed by atomic force microscopy
-
Qu M.H., Li H., Tian R., Nie C.L., Liu Y., Han B.S., He R.Q. Neuronal tau induces DNA conformational changes observed by atomic force microscopy. Neuroreport 2004, 15:2723-2727.
-
(2004)
Neuroreport
, vol.15
, pp. 2723-2727
-
-
Qu, M.H.1
Li, H.2
Tian, R.3
Nie, C.L.4
Liu, Y.5
Han, B.S.6
He, R.Q.7
-
35
-
-
84969001783
-
The attraction of proteins for small molecules and ions
-
Scatchard G. The attraction of proteins for small molecules and ions. Ann. N. Y. Acad. Sci. U.S.A. 1949, 51:660-672.
-
(1949)
Ann. N. Y. Acad. Sci. U.S.A.
, vol.51
, pp. 660-672
-
-
Scatchard, G.1
-
36
-
-
33644916708
-
Nuclear pore complex proteins in Alzheimer disease
-
Sheffield L.G., Miskiewicz H.B., Tannenbaum L.B., Mirra S.S. Nuclear pore complex proteins in Alzheimer disease. J. Neuropathol. Exp. Neurol. 2006, 65:45-54.
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, pp. 45-54
-
-
Sheffield, L.G.1
Miskiewicz, H.B.2
Tannenbaum, L.B.3
Mirra, S.S.4
-
37
-
-
33745184916
-
Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization
-
Sjöberg M.K., Shestakova E., Mansuroglu Z., Maccioni R.B., Bonnefoy E. Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization. J. Cell. Sci. 2006, 119:2025-2034.
-
(2006)
J. Cell. Sci.
, vol.119
, pp. 2025-2034
-
-
Sjöberg, M.K.1
Shestakova, E.2
Mansuroglu, Z.3
Maccioni, R.B.4
Bonnefoy, E.5
-
38
-
-
0031576359
-
Characterization of tau proteins in human neuroblastoma SH-SY5Y cell line
-
Uberti D., Rizzini C., Spano P.F., Memo M. Characterization of tau proteins in human neuroblastoma SH-SY5Y cell line. Neurosci. Lett. 1997, 235:149-153.
-
(1997)
Neurosci. Lett.
, vol.235
, pp. 149-153
-
-
Uberti, D.1
Rizzini, C.2
Spano, P.F.3
Memo, M.4
-
39
-
-
43249124363
-
Microtubule-associated protein tau in development, degeneration and protection of neurons
-
Wang J.Z., Liu F. Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog. Neurobiol. 2008, 85:148-175.
-
(2008)
Prog. Neurobiol.
, vol.85
, pp. 148-175
-
-
Wang, J.Z.1
Liu, F.2
-
40
-
-
49749097123
-
Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation
-
Wei Y., Qu M.H., Wang X.S., Chen L., Wang D.L., Liu Y., Hua Q., He R.Q. Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation. PLoS ONE 2008, 3:e2600.
-
(2008)
PLoS ONE
, vol.3
-
-
Wei, Y.1
Qu, M.H.2
Wang, X.S.3
Chen, L.4
Wang, D.L.5
Liu, Y.6
Hua, Q.7
He, R.Q.8
-
41
-
-
0008538685
-
A protein factor essential for microtubule assembly
-
Weingarten M.D., Lockwood A.H., Hwo S.Y., Kirschner M.W. A protein factor essential for microtubule assembly. Proc. Natl. Acad. Sci. U.S.A. 1975, 72:1858-1862.
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 1858-1862
-
-
Weingarten, M.D.1
Lockwood, A.H.2
Hwo, S.Y.3
Kirschner, M.W.4
-
42
-
-
33748372746
-
Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau
-
Williams D.R. Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau. Intern. Med. J. 2006, 36:652-660.
-
(2006)
Intern. Med. J.
, vol.36
, pp. 652-660
-
-
Williams, D.R.1
-
43
-
-
0035958642
-
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles
-
Wittmann C.W., Wszolek M.F., Shulman J.M., Salvaterra P.M., Lewis J., Hutton M., Feany M.B. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 2001, 293:711-714.
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
44
-
-
32644467781
-
Oxidative stress induces nuclear translocation of C-terminus of alpha-synuclein in dopaminergic cells
-
Xu S., Zhou M., Yu S., Cai Y., Zhang A., Uéda K., Chan P. Oxidative stress induces nuclear translocation of C-terminus of alpha-synuclein in dopaminergic cells. Biochem. Biophys. Res. Commun. 2006, 342:330-335.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.342
, pp. 330-335
-
-
Xu, S.1
Zhou, M.2
Yu, S.3
Cai, Y.4
Zhang, A.5
Uéda, K.6
Chan, P.7
|