Neurovirulence and latency of drug-resistant clinical herpes simplex viruses in animal models

Journal of Medical Virology

Volumn 82, Issue 6, 2010, Pages 1000-1006

  Dambrosi, Sarah ^a   Martin, Mélanie ^a   Yim, Kevin ^b   Miles, Brian ^b   Canas, Julio ^b   Sergerie, Yan ^a   Boivin, Guy ^a  

^a LAVAL UNIVERSITY   (Canada)

^b Virion Systems Inc   (United States)

Author keywords

Acyclovir; Foscarnet; Herpes simplex virus; Latency; Resistance; Virulence

Indexed keywords

ACICLOVIR; DNA POLYMERASE; FOSCARNET; THYMIDINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG SENSITIVITY; FEMALE; GENE MUTATION; GENITAL TRACT INFECTION; HERPES SIMPLEX VIRUS; HISTOPATHOLOGY; HUMAN; IC 50; MOUSE; NONHUMAN; RAT; SURVIVAL RATE; VIRULENCE; VIRUS ENCEPHALITIS; VIRUS LOAD; VIRUS REPLICATION; WILD TYPE;

ANIMALS; CERCOPITHECUS AETHIOPS; DNA-DIRECTED DNA POLYMERASE; DRUG RESISTANCE, VIRAL; ENCEPHALITIS, HERPES SIMPLEX; EXODEOXYRIBONUCLEASES; FEMALE; GANGLIA, SPINAL; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; MUTATION, MISSENSE; SEQUENCE DELETION; SIGMODONTINAE; SIMPLEXVIRUS; SURVIVAL ANALYSIS; THYMIDINE KINASE; VERO CELLS; VIRAL PROTEINS; VIRULENCE; VIRUS LATENCY; VIRUS REPLICATION;

ANIMALIA; MUS; SIGMODON; SIMPLEXVIRUS;

EID: 77953528473     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21773     Document Type: Article

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