Characterization of the Roco protein family in Dictyostelium discoideum

Eukaryotic Cell

Volumn 9, Issue 5, 2010, Pages 751-761

  van Egmond, Wouter N ^a   van Haastert, Peter J M ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; PROTOZOAL PROTEIN;

ANTIBODY SPECIFICITY; ARTICLE; CYTOLOGY; DICTYOSTELIUM; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MULTIGENE FAMILY; MUTATION; PHENOTYPE; PHYLOGENY; PROMOTER REGION; PROTEIN TRANSPORT;

DICTYOSTELIUM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; MULTIGENE FAMILY; MUTATION; ORGAN SPECIFICITY; PHENOTYPE; PHYLOGENY; PROMOTER REGIONS, GENETIC; PROTEIN TRANSPORT; PROTOZOAN PROTEINS;

ACRASIDA; DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; POLYSPHONDYLIUM PALLIDUM;

EID: 77953527357     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00366-09     Document Type: Article

References (28)

1. Abe, T., J. Langenick, and J. G. Williams. 2003. Rapid generation of genedisruption constructs by in vitro transposition and identification of a Dictyostelium protein kinase that regulates its rate of growth and development. Nucleic Acids Res. 31: e107.
2. Abysalh, J. C., L. L. Kuchnicki, and D. A. Larochelle. 2003. The identifica-tion of pats1, a novel gene locus required for cytokinesis in Dictyostelium discoideum. Mol. Biol. Cell 14: 14-25.
3. Berg, D., K. Schweitzer, P. Leitner, A. Zimprich, P. Lichtner, P. Belcredi, T.Brussel, C. Schulte, S. Maass, and T. Nagele. 2005. Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease. Brain 128: 3000-3011.
4. Blanton, R. L., D. Fuller, N. Iranfar, M. J. Grimson, and W. F. Loomis. 2000.The cellulose synthase gene of Dictyostelium. Proc. Natl. Acad. Sci. U. S. A. 97: 2391-2396.
5. Bosgraaf, L., and P. J. van Haastert. 2003. Roc, a Ras/GTPase domain incomplex proteins. Biochim. Biophys. Acta 1643: 5-10.
6. Bosgraaf, L., A. Waijer, R. Engel, A. J. Visser, D. Wessels, D. Soll, and P. J.van Haastert. 2005. RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium. J. Cell Sci. 118: 1899-1910.
7. Bosgraaf, L., H. Russcher, J. L. Smith, D. Wessels, D. R. Soll, and P. J. vanHaastert. 2002. A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. EMBO J. 21: 4560-4570.
8. Dharmawardhane, S., A. B. Cubitt, A. M. Clark, and R. A. Firtel. 1994.Regulatory role of the G alpha 1 subunit in controlling cellular morphogenesis in Dictyostelium. Development 120: 3549-3561.
9. Goldberg, J. M., L. Bosgraaf, P. J. van Haastert, and J. L. Smith. 2002.Identification of four candidate cGMP targets in Dictyostelium. Proc. Natl. Acad. Sci. U. S. A. 99: 6749-6754.
10. Ho, C. C., H. J. Rideout, E. Ribe, C. M. Troy, and W. T. Dauer. 2009. TheParkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration. J. Neurosci. 29: 1011-1016.
11. Levraud, J. P., M. Adam, M. F. Luciani, C. de Chastellier, R. L. Blanton, andP. Golstein. 2003. Dictyostelium cell death: Early emergence and demise of highly polarized paddle cells. J. Cell Biol. 160: 1105-1114.
12. Marín, I. 2006. The Parkinson disease gene LRRK2: Evolutionary and struc-tural insights. Mol. Biol. Evol. 23: 2423-2433.
13. Marín, I. 2008. Ancient origin of the Parkinson disease gene LRRK2. J. Mol.Evol. 67: 41-50.
14. Marin, I., W. N. van Egmond, and P. J. van Haastert. 2008. The Rocoprotein family: A functional perspective. FASEB J. 22: 3103-3110.
15. Mata, I. F., W. J. Wedemeyer, M. J. Farrer, J. P. Taylor, and K. A. Gallo.2006. LRRK2 in Parkinson's disease: Protein domains and functional in-sights. Trends Neurosci. 29: 286-293.
16. Ohnishi, T., A. Takahashi, K. Okaichi, K. Ohnishi, H. Matsumoto, S. Takahashi, H. Yamanaka, T. Nakano, and S. Nagaoka. 1997. Cell growth and morphology of Dictyostelium discoideum in space environment. Biol. Sci. Space 11: 29-34.
17. Paisán-Ruíz, C., S. Jain, E. W. Evans, W. P. Gilks, J. Simón, M. van der Brug, A. López de Munain, S. Aparicio, A. M. Gil, N. Khan, J. Johnson, J. R. Martinez, D. Nicholl, I. M. Carrera, A. S. Pena, R. de Silva, A. Lees, J. F. Martí-Massó, J. Pérez-Tur, N. W. Wood, and A. B. Singleton. 2004. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 44: 595-600.
18. Pilcher, K. E., P. Gaudet, P. Fey, A. S. Kowal, and R. L. Chisholm. 2007. A general purpose method for extracting RNA from Dictyostelium cells. Nat. Protoc. 2: 1329-1332.
19. Rietdorf, J., F. Siegert, S. Dharmawardhane, R. A. Firtel, and C. J. Weijer. 1997. Analysis of cell movement and signalling during ring formation in an activated G alpha1 mutant of Dictyostelium discoideum that is defective in prestalk zone formation. Dev. Biol. 181: 79-90.
20. Schaap, P., T. Winckler, M. Nelson, E. Alvarez-Curto, B. Elgie, H. Hagiwara, J. Cavender, A. Milano-Curto, D. E. Rozen, T. Dingermann, R. Mutzel, and S. L. Baldauf. 2006. Molecular phylogeny and evolution of morphology in the social amoebas. Science 314: 661-663.
21. Sutoh, K. 1993. A transformation vector for dictyostelium discoideum with a new selectable marker bsr. Plasmid 30: 150-154.
22. Taylor, J. P., I. F. Mata, and M. J. Farrer. 2006. LRRK2: A common pathwayfor parkinsonism, pathogenesis and prevention? Trends Mol. Med. 12: 76-82.
23. van Egmond, W. N., A. Kortholt, K. Plak, L. Bosgraaf, S. Bosgraaf, I. Keizer-Gunnink, and P. J. van Haastert. 2008. Intramolecular activation mechanism of the Dictyostelium LRRK2homolog Roco protein GbpC. J. Biol. Chem. 283: 30412-30420.
24. Veltman, D. M., G. Akar, L. Bosgraaf, and P. J. van Haastert. 2009. A new set of small, extrachromosomal expression vectors for Dictyostelium discoideum. Plasmid 61: 110-118.
25. Veltman, D. M., I. Keizer-Gunnink, and P. J. van Haastert. 2008. Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum. J. Cell Biol. 180: 747-753.
26. West, A. B., D. J. Moore, C. Choi, S. A. Andrabi, X. Li, D. Dikeman, S. Biskup, Z. Zhang, K. L. Lim, V. L. Dawson, and T. M. Dawson. 2007. Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. Hum. Mol. Genet. 16: 223-232.
27. West, A. B., D. J. Moore, S. Biskup, A. Bugayenko, W. W. Smith, C. A. Ross, V. L. Dawson, and T. M. Dawson. 2005. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc. Natl. Acad. Sci. U. S. A. 102: 16842-16847.
28. Zimprich, A., S. Biskup, P. Leitner, P. Lichtner, M. Farrer, S. Lincoln, J. Kachergus, M. Hulihan, R. J. Uitti, D. B. Calne, A. J. Stoessl, R. F. Pfeiffer, N. Patenge, I. C. Carbajal, P. Vieregge, F. Asmus, B. Müller-Myhsok, D. W. Dickson, T. Meitinger, T. M. Strom, Z. K. Wszolek, and T. Gasser. 2004. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44: 601-607.