Investigations of cellular glucose transport and its regulation under the influence of insulin in human peripheral blood lymphocytes

Endokrynologia Polska

Volumn 61, Issue 2, 2010, Pages 182-187

  Pia̧tkiewicz, Paweł ^a   Czech, Anna ^a   Tatoń, Jan ^a   Górski, Andrzej ^b  

^a Brodnowski Hospital Warsaw   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Flow cytometry; Glucose transport; GLUT1; GLUT3; GLUT4; Insulin; Lymphocytes

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4; INSULIN; PHYCOERYTHRIN;

ARTICLE; BLOOD ANALYSIS; CELL LEVEL; CELL MEMBRANE; CONTROLLED STUDY; DYNAMICS; FLOW CYTOMETRY; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; INSULIN RESISTANCE; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; REGULATORY MECHANISM;

CELL MEMBRANE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 3; GLUCOSE TRANSPORTER TYPE 4; HUMANS; INSULIN; INSULIN RESISTANCE; LYMPHOCYTES; PROTEIN ISOFORMS; REFERENCE VALUES;

EID: 77953497992     PISSN: 0423104X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Moller D, Flier J. Insulin resistance: syndromes and implications. N Engl J Med 1991; 325: 938-946.
2. Le Roith D, Zick Y. Recent advances in our understanding of insulin action and insulin resistance. Diabetes Care 2001; 24: 588-597. (Pubitemid 32198431)
3. Pia̧tkiewicz P., Czech A., Tatoń J. Glucose transport in human peripheral blood lymphocytes influenced by type 2 diabetic patients. Arch Immunol Therp Exp 2007; 55: 1-8.
4. Estrada DE, Elliott E, Zinman B et al. Regulation of glucose transport and expression of GLUT3 transporters in human circulating mononuclear cells: studies in cells from insulin-dependent diabetic and nondiabetic individuals. Metabol Clin & Exptl 1994; 43: 591-598. (Pubitemid 24145466)
5. Curto M, Piccinini M, Rabbone I et al. G proteins and regulation of pyruvate dehydrogenase activity by insulin in human circulating lymphocytes. Int J Biochem & Cell Biol 1997; 29: 1207-1217. (Pubitemid 27522559)
6. Mostert M, Rabbone I, Piccinini M et al. Derangements of pyruvate dehydrogenase in circulating lymphocytes of NIDDM patients and their healthy offspring. J Endocrinol Invest 1999; 22: 519-526. (Pubitemid 29425451)
7. Daneman D, Zinman B, Elliott E et al. Insulin-stimulated glucose transport in circulating mononuclear cells from non-diabetic and IDDM subjects. Diabetes 1992; 41: 227-234.
8. Kelley J, Rosek M, Suenram C et al. Activation of human bloodmonocytes by adherence to tissue culture plastic surfaces. Exp Mol Pathol 1987; 46: 266-278. (Pubitemid 17094294)
9. Aller C, Ehlman S, Gilman-Sachs A et al. Flow cytometric analysis of glucose transport in rat brain cells. Cytometry 1997; 27: 262-268. (Pubitemid 27130205)
10. Stewart C, Stewart S. Current protocols in cytometry. Immunophe-notyping 1997; P 6.2.1-P 6.2.18.
11. Piçtkiewicz P, Szablewski L, Czech A et al. Badania transportu glukozy do limfocytów u osób zdrowych i chorych na cukrzycȩ typu 2. Medycyna Metaboliczna, 2002, Tom VI, Nr 4, 15-21.
12. Szablewski L, Pia̧tkiewicz P, Oleszczak B et al. Wpływ leczenia insulina̧ i cukrzycy typu 2 na pobieranie deoksy-D-glukozy przez limfocyty krwi obwodowej. Diabetologia Doświadczalna i Kliniczna. 2004; 4: 217-223.
13. Kaliman P, Vińals F, Testar X et al. Disruption of GLUT1 glucose carrier trafficking in L6E9 and Sol8 myoblasts by the phosphatidylinositol 3-kinase inhibitor wortmannin. Biochem J 1995; 312: 471-477. (Pubitemid 26002213)
14. Pia̧tkiewicz P, Kłosowska D, Czech A et al. Investigations of Glucotransporter 4 (GLUT4) expression in lymphocytes of healthy subjects and type 2 diabetic patients. Immunology 2004; 50: 203-206.
15. Pia̧tkiewicz P, Tatoń J, Czech A et al. Investigations of glucotransporter 4 (GLUT4) expression in lymphocytes of healthy subjects and type 2 diabetic patients. [Abstract]. Diabetologia 2004; 47 (Suppl.): 450.
16. Newsholme E, Dimitriadis G. Integration of biochemical and physiologic effects of insulin on glucose metabolism. Exp Clin Endocrinol Diabetes 2001; 109(Suppl 2): 122-134.
17. Kahn B. Glucose transport: a pivotal step in insulin action. Diabetes1996; 45: 1644-1654.
18. Gould G, Holman G. The glucose transporter family: structure, function and tissue-speci?c expression. Biochem J 1993; 295: 329-341. (Pubitemid 23315168)
19. Wilson C, Mitsumoto Y, Maher F et al. Regulation of cell surfaceGLUT1, GLUT3 and GLUT4 by insulin and IGF1 in L6 myotubes. FEBSLett 1995; 368: 19-22.
20. Korgun E, Demir R, Sedlmayr P et al. Sustained hypoglycemia affects glucose transporter expression of human blood leucocytes. Blood Cells Mol Dis 2002; 28: 152-159.
21. Estrada E, Elliott E, Zinman B et al. Regulation of glucose transport and expression of GLUT3 transporters in human circulating mononuclear cells: studies in cells from insulin-dependent diabetic and non-diabetic individuals. Metabolism 1994; 43: 591-598. (Pubitemid 24145466)
22. Zierath Z. In-vitro studies of human skeletal muscle: hormonal and metabolic regulation of glucose transport. Acta Physiol Scand 1995; 155 (Suppl. 626): 14-43.
23. Dimitriadis G, Leighton B, Parry-Billings M et al. Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle. Biochem J 1997; 321: 707-712. (Pubitemid 27084879)
24. Rizza R, Mandarino L, Gerich J. Dose-response characteristics foreffects of insulin on production and utilization of glucose in man. Am J Physiol 1981; 240: E630-E639.
25. Kraegen E, James D, Jenkins A et al. Dose-response curves for in-vivo insulin sensitivity in individual tissues in rats. Am J Physiol 1985; 248: E353-E362.
26. Rosetti L, Giaccari A. Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. J Clin Invest 1990; 85: 1785-1792.
27. Ciaraldi T, Kolterman O, Siegel J et al. Insulin-stimulated glucose transport in human adipocytes. Am J Physiol 1979; 236: E621-E625. (Pubitemid 9220481)
28. Wardzala L, Hirshman M, Pofcher E et al. Regulation of glucose utilization in adipose cells and muscle after long-term experimental hyperinsulinemia in rats. J Clin Invest 1985; 76: 460-469. (Pubitemid 15227506)
29. Maegawa H, Kobayashi M, Ishibashi O et al. effect of diet change on insulin action: difference between muscle and adipocytes. Am J Physiol 1986; 251: E616-E623.
30. Bonen A, Clark M, Henriksen E. Experimental approaches in muscle metabolism: hindlimb perfusion and isolated muscle incubations. Am J Physiol 1994; 266: E1-E16. (Pubitemid 24058314)
31. Dimitriadis G, Parry-Billings M, Bevan S et al. The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats. Eur J Clin Invest 1997; 27: 475-483. (Pubitemid 27288357)
32. Rizza R, Mandarino L, Gerich J. Mechanism and signi?cance of insulin resistance in non-insulin dependent diabetes mellitus. Diabetes 1981; 30: 990-995.