Apoptotic regulation by MCL-1 through heterodimerization

Journal of Biological Chemistry

Volumn 285, Issue 25, 2010, Pages 19615-19624

  Liu, Qian ^a   Moldoveanu, Tudor ^a,b   Sprules, Tara ^a   Matta Camacho, Edna ^a   Mansur Azzam, Nura ^a   Gehring, Kalle ^a  

^a MCGILL UNIVERSITY   (Canada)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC; BCL-2 FAMILY; CALPAINS; DRUG DISCOVERY; HETERODIMERIZATION; HUMAN CANCER; HUMAN TUMORS; IN-CELL; IN-VITRO; LIGAND BINDING; LIMITED PROTEOLYSIS; MYELOID CELLS; N-TERMINALS; NMR SPECTROSCOPY; NMR TITRATION; PROTEIN PRODUCTION; PROTEIN-PROTEIN INTERACTIONS; SOLUTION STRUCTURES; STRUCTURAL CHARACTERIZATION; TITRATION CALORIMETRY;

CELL DEATH; COMPLEXATION; LIGANDS; MAMMALS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; TITRATION;

SIZE EXCLUSION CHROMATOGRAPHY;

BH3 PROTEIN; CALPAIN; PROTEIN BCL 2; PROTEIN BID; PROTEIN MCL 1;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CALORIMETRY; CONTROLLED STUDY; DIMERIZATION; DRUG RESEARCH; GEL PERMEATION CHROMATOGRAPHY; HEMATOPOIESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; MAMMAL; MITOCHONDRION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; APOPTOSIS; CALORIMETRY; CALPAIN; DIMERIZATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PROTEIN INTERACTION MAPPING; PROTO-ONCOGENE PROTEINS C-BCL-2; SEQUENCE HOMOLOGY, AMINO ACID;

MAMMALIA;

EID: 77953483909     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.105452     Document Type: Article

References (49)

1. Chipuk, J. E., Moldoveanu, T., Llambi, F., Parsons, M. J., and Green, D. R. (2010) Mol. Cell 37, 299-310
2. Warr, M. R., Acoca, S., Liu, Z., Germain, M., Watson, M., Blanchette, M., Wing, S. S., and Shore, G. C. (2005) FEBS Lett. 579, 5603-5608
3. Zhong, Q., Gao, W., Du, F., and Wang, X. (2005) Cell 121, 1085-1095
4. Han, J., Goldstein, L. A., Gastman, B. R., Rabinovitz, A., and Rabinowich, H. (2005) J. Biol. Chem. 280, 16383-16392
5. Weng, C., Li, Y., Xu, D., Shi, Y., and Tang, H. (2005) J. Biol. Chem. 280, 10491-10500
6. Kobayashi, S., Lee, S. H., Meng, X. W., Mott, J. L., Bronk, S. F., Werneburg, N. W., Craig, R. W., Kaufmann, S. H., and Gores, G. J. (2007) J. Biol. Chem. 282, 18407-18417
7. Ding, Q., Huo, L., Yang, J. Y., Xia, W., Wei, Y., Liao, Y., Chang, C. J., Yang, Y., Lai, C. C., Lee, D. F., Yen, C. J., Chen, Y. J., Hsu, J. M., Kuo, H. P., Lin, C. Y., Tsai, F. J., Li, L. Y., Tsai, C. H., and Hung, M. C. (2008) Cancer Res. 68, 6109-6117
8. Derenne, S., Monia, B., Dean, N. M., Taylor, J. K., Rapp, M. J., Harousseau, J. L., Bataille, R., and Amiot, M. (2002) Blood 100, 194-199
9. Alvi, A. J., Austen, B., Weston, V. J., Fegan, C., MacCallum, D., Gianella-Borradori, A., Lane, D. P., Hubank, M., Powell, J. E., Wei, W., Taylor, A. M., Moss, P. A., and Stankovic, T. (2005) Blood 105, 4484-4491
10. Cavarretta, I. T., Neuwirt, H., Untergasser, G., Moser, P. L., Zaki, M. H., Steiner, H., Rumpold, H., Fuchs, D., Hobisch, A., Nemeth, J. A., and Culig, Z. (2007) Oncogene 26, 2822-2832
11. Sieghart, W., Losert, D., Strommer, S., Cejka, D., Schmid, K., Rasoul-Rockenschaub, S., Bodingbauer, M., Crevenna, R., Monia, B. P., Peck-Radosavljevic, M., and Wacheck, V. (2006) J. Hepatol. 44, 151-157
12. Fesik, S. W. (2005) Nat. Rev. Cancer 5, 876-885
13. Li, H., Zhu, H., Xu, C. J., and Yuan, J. (1998) Cell 94, 491-501
14. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998) Cell 94, 481-490
15. Wei, M. C., Lindsten, T., Mootha, V. K., Weiler, S., Gross, A., Ashiya, M., Thompson, C. B., and Korsmeyer, S. J. (2000) Genes Dev. 14, 2060-2071
16. Clohessy, J. G., Zhuang, J., de Boer, J., Gil-Gómez, G., and Brady, H. J. (2006) J. Biol. Chem. 281, 5750-5759
17. Moldoveanu, T., Liu, Q., Tocilj, A., Watson, M., Shore, G., and Gehring, K. (2006) Mol. Cell 24, 677-688
18. Denisov, A. Y., Chen, G., Sprules, T., Moldoveanu, T., Beauparlant, P., and Gehring, K. (2006) Biochemistry 45, 2250-2256
19. Moldoveanu, T., Hosfield, C. M., Lim, D., Elce, J. S., Jia, Z., and Davies, P. L. (2002) Cell 108, 649-660
20. Goping, I. S., Gross, A., Lavoie, J. N., Nguyen, M., Jemmerson, R., Roth, K., Korsmeyer, S. J., and Shore, G. C. (1998) J. Cell Biol. 143, 207-215
21. Cavanagh, J. (1996) Protein NMR Spectroscopy: Principles and Practice, Academic Press, San Diego
22. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
23. Johnson, B. A., and Blevins, R. A. (1994) J. Biomol. NMR 4, 603-614
24. Clore, G. M., and Gronenborn, A.M.(1994) Methods Enzymol. 239, 349-363
25. Peng, J. W., and Wagner, G. (1994) Methods Enzymol. 239, 563-596
26. Ottiger, M., Delaglio, F., and Bax, A. (1998) J. Magn. Reson. 131, 373-378
27. Cornilescu, G., Delaglio, F., and Bax, A. (1999) J. Biomol. NMR 13, 289-302
28. Güntert, P. (2004) Methods Mol. Biol. 278, 353-378
29. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
30. Laskowski, R. A., Rullmannn, J. A., MacArthur, M. W., Kaptein, R., and Thornton, J. M. (1996) J. Biomol. NMR 8, 477-486
31. Delano, W. L. (2002) The PyMOL Molecular Graphics System, DeLano Scientific, San Carlos, CA
32. Day, C. L., Chen, L., Richardson, S. J., Harrison, P. J., Huang, D. C., and Hinds, M. G. (2005) J. Biol. Chem. 280, 4738-4744
33. Czabotar, P. E., Lee, E. F., van Delft, M. F., Day, C. L., Smith, B. J., Huang, D. C., Fairlie, W. D., Hinds, M. G., and Colman, P. M. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 6217-6222
34. Day, C. L., Smits, C., Fan, F. C., Lee, E. F., Fairlie, W. D., and Hinds, M. G. (2008) J. Mol. Biol. 380, 958-971
35. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815
36. Mandic, A., Viktorsson, K., Strandberg, L., Heiden, T., Hansson, J., Linder, S., and Shoshan, M. C. (2002) Mol. Cell Biol. 22, 3003-3013
37. Chou, J. J., Li, H., Salvesen, G. S., Yuan, J., and Wagner, G. (1999) Cell 96, 615-624
38. Meiler, J., Prompers, J. J., Peti, W., Griesinger, C., and Brüschweiler, R. (2001) J. Am. Chem. Soc. 123, 6098-6107
39. Craig, R. W. (2002) Leukemia 16, 444-454
40. Willis, S. N., Chen, L., Dewson, G., Wei, A., Naik, E., Fletcher, J. I., Adams, J. M., and Huang, D. C. (2005) Genes Dev. 19, 1294-1305
41. Brunelle, J. K., Shroff, E. H., Perlman, H., Strasser, A., Moraes, C. T., Flavell, R. A., Danial, N. N., Keith, B., Thompson, C. B., and Chandel, N. S. (2007) Mol. Cell. Biol. 27, 1222-1235
42. Oltersdorf, T., Elmore, S. W., Shoemaker, A. R., Armstrong, R. C., Augeri, D. J., Belli, B. A., Bruncko, M., Deckwerth, T. L., Dinges, J., Hajduk, P. J., Joseph, M. K., Kitada, S., Korsmeyer, S. J., Kunzer, A. R., Letai, A., Li, C., Mitten, M. J., Nettesheim, D. G., Ng, S., Nimmer, P. M., O'Connor, J. M., Oleksijew, A., Petros, A. M., Reed, J. C., Shen, W., Tahir, S. K., Thompson, C. B., Tomaselli, K. J., Wang, B., Wendt, M. D., Zhang, H., Fesik, S. W., and Rosenberg, S. H. (2005) Nature 435, 677-681
43. Konopleva, M., Contractor, R., Tsao, T., Samudio, I., Ruvolo, P. P., Kitada, S., Deng, X., Zhai, D., Shi, Y. X., Sneed, T., Verhaegen, M., Soengas, M., Ruvolo, V. R., McQueen, T., Schober, W. D., Watt, J. C., Jiffar, T., Ling, X., Marini, F. C., Harris, D., Dietrich, M., Estrov, Z., McCubrey, J., May, W. S., Reed, J. C., and Andreeff, M. (2006) Cancer Cell 10, 375-388
44. Chauhan, D., Velankar, M., Brahmandam, M., Hideshima, T., Podar, K., Richardson, P., Schlossman, R., Ghobrial, I., Raje, N., Munshi, N., and Anderson, K. C. (2007) Oncogene 26, 2374-2380
45. Trudel, S., Stewart, A. K., Li, Z., Shu, Y., Liang, S. B., Trieu, Y., Reece, D., Paterson, J., Wang, D., and Wen, X. Y. (2007) Clin. Cancer Res. 13, 621-629
46. Chen, L., Willis, S. N., Wei, A., Smith, B. J., Fletcher, J. I., Hinds, M. G., Colman, P. M., Day, C. L., Adams, J. M., and Huang, D. C. (2005) Mol. Cell 17, 393-403
47. Certo, M., Del Gaizo Moore, V., Nishino, M., Wei, G., Korsmeyer, S., Armstrong, S. A., and Letai, A. (2006) Cancer Cell 9, 351-365
48. Germain, M., and Duronio, V. (2007) J. Biol. Chem. 282, 32233-32242
49. Yao, Y., Bobkov, A. A., Plesniak, L. A., and Marassi, F. M. (2009) Biochemistry 48, 8704-8711