Phenotypic fingerprinting of small molecule cell cycle kinase inhibitors for drug discovery

Current Chemical Genomics

Volumn 3, Issue 1, 2009, Pages 13-21

  Low, Jonathan ^a   Chakravartty, Arunava ^a   Blosser, Wayne ^a   Dowless, Michele ^a   Chalfant, Christopher ^b   Bragger, Patty ^b   Stancato, Louis ^a,b  

^a Department of Cancer Growth and Translational Genetics ^*  (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 [[3 [4 [5 [2 (3 FLUOROANILINO) 2 OXOETHYL] 1H PYRAZOL 3 YLAMINO] 7 QUINAZOLINYLOXY]PROPYL](ETHYL)AMINO]ETHYL DIHYDROGEN PHOSPHATE; 4 [[9 CHLORO 7 (2,6 DIFLUOROPHENYL) 5H PYRIMIDO[5,4 D][2]BENZAZEPIN 2 YL]AMINO]BENZOIC ACID; 6 ACETYL 8 CYCLOPENTYL 5 METHYL 2 [5 (1 PIPERAZINYL) 2 PYRIDINYLAMINO] 8H PYRIDO[2,3 D]PYRIMIDIN 7 ONE; AG 024322; AG 12286; AURORA A KINASE; BERLEX; BI 2536; BMI 1026; BMS 265246; CYCLOPROPANECARBOXYLIC ACID [4 [4 (4 METHYL 1 PIPERAZINYL) 6 (5 METHYL 2H PYRAZOL 3 YLAMINO) 2 PYRIMIDINYLTHIO]PHENYL]AMIDE; FLAVOPIRIDOL; GSK 461364; HMN 214; N [5 (5 TERT BUTYL 2 OXAZOLYLMETHYLTHIO) 2 THIAZOLYL]ISONIPECOTAMIDE; ON 01910NA; PD 171851; PHA 680632; PHA 739358; PHOSPHOTRANSFERASE INHIBITOR; PURVALANOL A; QUINAZOLINE; R 547; ROSCOVITINE; SCH 727965; TOZASERTIB LACTATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE ARREST; COMPUTER ANALYSIS; CONTROLLED STUDY; DRUG TARGETING; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; PHENOTYPE; PRIORITY JOURNAL;

EID: 77953464785     PISSN: None     EISSN: 18753973     Source Type: Journal    
DOI: 10.2174/1875397300903010013     Document Type: Article

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