Attenuation of diabetic disorders in experimentally induced diabetic rat by methanol extract of seed of Holarrhena antidysenterica

International Journal of PharmTech Research

Volumn 1, Issue 4, 2009, Pages 1205-1211

  Ali, Kazi Monjur ^a   Bera, Tushar Kanti ^a   Mandal, Suvra ^b   Barik, Bikash Ranjan ^b   Ghosh, Debidas ^a  

^a VIDYASAGAR UNIVERSITY   (India)

^b Central Research Institute Ayurveda   (India)

Author keywords

Antidiabetic; Antihyperlipidemic; Carbohydrate metabolic enzymes; Glycogen; Holarrhena antidysenterica

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; GLIBENCLAMIDE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLYCOGEN; HEXOKINASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOLARRHENA ANTIDYSENTERICA EXTRACT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHANOL; PLANT EXTRACT; STREPTOZOCIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CHOLESTEROL BLOOD LEVEL; CONTINUOUS INFUSION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFICACY; ENZYME ACTIVITY; EXPERIMENTAL RAT; GLUCOSE BLOOD LEVEL; HOLARRHENA; HOLARRHENA ANTIDYSENTERICA; LIPID ANALYSIS; MALE; NONHUMAN; PLANT SEED; RAT; STREPTOZOCIN DIABETES;

EID: 77953461954     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Scheen J.A., Drug treatment of non-insulin dependent diabetes mellitus in the 1990s Achievements and future development, Drug, 1997, 54, 355-368.
2. Tiwari A.K. and Madhusudana R.J., Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects, Curr. Sci, 2002, 83, 30-38.
3. Bhattaram V.A. Graefe U. Kohlert C. Veit M. and Derendorf H., Pharmacokinetics and bioavailability of herbal medicinal products, Phytomed, 2002, 9, 1-36.
4. Miura T. Kubo M. Itoh Y. Iwamoto N. Kato M. Park R.S. Ukawa Y. Kita Y. and Suzuki I., Antidiabetic activity of Lyophyllum decastes in Genetically Type 2 Diabetic Mice, Biol. Pharm. Bull, 2002, 25, 1234-1237.
5. WHO., Traditional Medicine strategy 2002-2005, World Health Organization, Geneva, 2002, pp 74.
6. Kavitha D. Shilpa P.N. Devaraj S.N., Antibacterial and antidiarrhoel effects of alkaloids of Holarrhena antidysenterica Wall, Ind. J. Exp. Biol., 2004, 4, 589-594.
7. Sing K.P., Entamoeba histolytica and Holarrhena antidysenterica, Ancient Science of Life, 1986, 5, 228.
8. Wahab M.A. and Yousuf M., Ethno-medical uses of some medicinally active plants for treating diabetes in Chittagong Hill Tracts , Bangladesh, Hamdard Medicus, 2004, 47, 36-38.
9. Pankaj N.K. Alam M. Roy B.K., Antidiabetic activity of seed powder of Holarrhena antidysenterica in rabbits, J. of. Res., 2005, 17, 95-103.
10. Sokeng S.D. Lontsi D. Moundipa P.F. Jatsa H.B. Watcho P. and Kamtchouing P., Hypoglycemic effect of Anacardium occidentale L. Methanol extracts and fractions on Streptozotocin-induced diabetic rats, 2007, Res. J. of Medicine & Med. Sci., 2, 133-137.
11. Lenzen S., The mechanisms of action of alloxan-and streptozotocin-induced diabetes, Diabetologia, 2008, 51, 216-226.
12. Sellamuthu P.S. Muniappan B.P. Perumal S.M. Kandasamy M.,. Antihyperglycemic effect of Mangiferin in Streptozotocin Induced Diabetic rats, J. Health. Sci., 2009, 55, 206-214.
13. Mallick C. Chatterjee K. GuhaBiswas M. and Ghosh D., Antihyperglycemic effects of separate and composite extract of root of Musa paradisiaca and leaf of Coccinia Indica in Streptozotocin induced Diabetic male albino rat, Afr. J. Trad. CAM ., 2007, 4, 362-371.
14. Chou A.C. Wilson J.E., Carbohydrate metabolism. In: Wood WA, (ed.) Methods in Enzymol. Vol.XIII. New York, Academic Press, 1975 pp 20-21.
15. Langdon R.G., Glucose-6-phosphate dehydrogenase from erythrocytes. In: Wood WA, (ed.) Methods in Enzymol. Vol.IX. New York, Academic Press, 1966, pp 126-131.
16. Swanson M.A., Glucose-6-phosphatase from liver. In: Colowick, S.P. Kaplan N.O. eds., Methods in Enzymes. Vol.II. New York, Academic Press, 1955, pp 541-543.
17. Sadasivam S. Manickam A., Carbohydrates. In: Sadasivam S, Manickam A, eds, Methods in Biochemistry, New Age International Pvt. Ltd. 1996, pp 11-12.
18. Desai S.A. Mani U.V. Lyer U.M., Serum lipids, apolipoproteins and total antioxidant activity levels of obese, diabetic and hypertensive subjects in an industrial set up in Baroda, Gujarat, India, Int. J. Diab. Dev. Countries, 2002, 22, 91-99.
19. Allain C.C. Poon L.S., Chan C.S.G., Enzymatic determination of total serum cholesterol, Clin. Chem., 1974, 20, 470-475.
20. Friedewald W.T. Levy K.J. Frederickson D.S., Estimation of concentration of LDL in plasma without of preparative ultracentrifuge, Clin. Chem., 1972, 18, 499-502.
21. Waenic R.G. Albers J.J., A comprehensive evaluation of the heparin manganese precipitation procedure for estimating high density lipoprotein cholesterol, J. Lipid. Res., 1978, 19, 65-76. (Pubitemid 8268303)
22. Henry R.J. Chiamori M. Gonub O.J. Berkman S., Revised spectrophotometric methods for the determination of glutamate oxaloacetic transaminase, glutamic pyruvate transaminase and lactic acid dehydrogenase. Am. J. Clin. Pathol., 1960, 34, 381-398.
23. Sokal R.R. and Rohle F.J., Introduction to Analysis of Variance, WH Freeman and Company, New York, 1997, 179-206.
24. Bailey C.J. and Flatt P.R., Animal models of diabetes. In: Nattras M.[Ed], Recent advances in Diabetes II. Churchill Livingstone, Edinburg, UK, 1986, pp, 71-89.
25. Chauhan S. Nath N. and Tule V., Antidiabetic and antioxidant effects of Picrorhiza kurrooa rhizome extracts in diabetic rats, Ind. J. Cli. Biochem., 2008, 23, 238-242.
26. Mandal S. Barik B. Mallick C. De D. and Ghosh D., Therapeutic Effect of Ferulic Acid, an Etheral Fraction of Ethanolic Extract of Seed of Syzygium cumini Against Streptozotocin-Induced Diabetes in Male Rat, Methods Find. Exp. Clin. Pharmacol., 2008, 30, 121-128.
27. Mallick C. Chatterjee K. Mandal U. and Ghosh D., Antihyperglycemic, Antilipidperoxidative and Antioxidative Effects of Extracts of Musa paradisiaca and Coccinia indica in Streptozotocin-Induced Diabetic Rat, Ethiop. Pharm. J 2007 25, 9-22.
28. Chattopadhyay R.R. and Bandyopadhyay M., Effect of Azadirachta indica on serum lipid profile changes in normal and streptozotocin induced diabetic rats, Afr. J. Biomed. Res., 2005, 8, 101-104.
29. Maiti R. Das U.K. and Ghosh D., Attenuation of hyperglycaemia in STZ induced diabetic rats by aqueous extract of seed of Tamarindus indica, Biol. Pharm. Bull., 2005, 28, 1172-1176.
30. Yadav J.P. Saini S. Kalia A.N. and Dangi A.S., Hypoglycemic and hypolipidemic activity of ethanolic extract of Salvadora oleoides in normal and alloxan-induced diabetic rats, Ind. J. Pharmacol., 2008, 40, 23-27.
31. Ugochukwu N.H., Babady N.E., Cobourne M. and Gasset S.R., The effect of Gongronema latifolium extracts on serum lipid profile and oxidative stress in hepatocytes of diabetic rats., J. Biosci., 2003, 28, 1-5.
32. Akther M.H. Mathur M. and Vhide N.K., Skin and liver toxicity in experimental Lantanc camara poisoning in albino rats., Ind.J.physiol.pharmacol., 1990, 34, 13-16.