The effect of Gongronema latifolium extracts on serum lipid profile and oxidative stress in hepatocytes of diabetic rats

Journal of Biosciences

Volumn 28, Issue 1, 2003, Pages 1-5

  Ugochukwu, N H ^a   Babady, N E ^a   Cobourne, M ^a   Gasset, S R ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

Diabetes; Gongronema latifolium; Lipid profile; Oxidative stress

Indexed keywords

ALCOHOL; CATALASE; GLUTATHIONE PEROXIDASE; GONGRONEMA LATIFOLIUM EXTRACT; MALONALDEHYDE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

DIABETES;

ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ASCLEPIADACEAE; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; GONGRONEMA LATIFOLIUM; LIPID BLOOD LEVEL; LIPID METABOLISM; LIPID PEROXIDATION; LIVER CELL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALIA; APOCYNACEAE; GONGRONEMA; GONGRONEMA LATIFOLIUM;

EID: 0037331798     PISSN: 02505991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02970124     Document Type: Conference Paper

References (25)

1. Aebi H 1984 Catalase in vitro; Methods Enzymol. 105 121-126
2. Akhtar M S and Ali M R 1984 Study of antidiabetic effect of a compound medicinal plant prescription in normal and diabetic rabbits; J. Pakistan. Med. Assoc. 34 239-244
3. Aydin A, Orhan H, Sayal A, Ozata M, Sahin G and Isimer A 2001 Oxidative stress and nitric oxide related parameters in type II diabetes mellitus: effect of glycemic control; Clin. Biochem. 34 65-70
4. Betteridge D J 1994 Diabetic dyslipidemia; Am. J. Med. (Suppl. 6A) 96 25S-31S
5. Bierman E L 1992 Atherogenesis in diabetes; Arterioscler. Thromb. 12 647-656
6. Ceriello A, Quatraro A and Giugliano D 1992 New insights on non-enzymatic glycosylation may lead to therapeutic approaches for the prevention of the diabetic complications; Diabet. Med. 9 297-299
7. Cho S-Y, Park J-Y, Park E M, Choi M S, Lee M-Y, Jeon S M, Jang M-K, Kim M J and Park Y-B 2002 Alternation of hepatic antioxidant enzyme activities and lipid profile in streptozotocin-induced diabetic rats by supplementation of dandelion water extract; Clin. Chim. Acta 317 109-117
8. Hartnett E M, Stratton R D, Browne R W, Rosner B A, Lanham R J and Armstrong D 2000 Serum Markers of oxidative stress and severity of diabetic retinopathy; Diabet. Care 23 234-240
9. Hodgson E K and Fridovich I 1975 The interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide: inactivation of the enzyme; Biochemistry 14 5294-5299
10. Izawa S, Inoue Y and Kimura A 1996 Importance of catalase in the adaptive response to hydrogen peroxide: analysis of acatalasaemic Saccharomyces cerevisiae; Biochem. J. (Pt 1) 320 61-67
11. Kesavulu M M, Giri R, Kameswara R B and Apparao C 2000 Lipid peroxidation and antioxidant enzyme levels in type 2 diabetic with microvascular complications; Diabet. Metabol. 26 387-392
12. Levy U, Zaltzber H, Ben-Amotz A, Kanter Y and Aviram M 1999 β-Carotene affects antioxidant status in non-insulin dependent diabetes mellitus; Pathophysiology 6 157-161
13. Morebise O, Fafunso M A, Makinde J M, Olajide O A and Awe E O 2002 Anti-inflammatory property of the leaves of Gongronema latifolium; Phytother. Res. 16 S75-S77
14. Okafor J C 1981 Woody plants of nutritional importance in traditional systems of the Nigerian humid tropics, Ph D thesis, University of Ibadan, Ibadan
15. Okafor J C 1987 Identification and conservation of plants used in traditional medicines (Lead lecture presented at the International Workshop on Evaluation of Traditional Medicine, University of Nigeria, Nsukka)
16. Okafor J C 1989 Tropical plants in health-care delivery (Guest lecture delivered to Pharmacognosy Society of Nigeria at the University of Nigeria, Nsukka)
17. Orchard T J 1990 Dyslipoproteinemia and diabetes; Endocrinol. Metab. Clin. North Am. 19 361-379
18. Paglia D and Valentine W 1967 Studies on the quantitative and qualitative characterization of erythtrocyte glutathione peroxidase; J. Lab. Clin. Med. 70 158-169
19. Scoppola A, Montecchi F R, Mezinger G and Lala A 2001 Urinary mevalonate excretion rate in type 2 diabetes: role of metabolic control; Atherosclerosis 156 357-361
20. Searle A J and Willson R L 1980 Glutathione peroxidase: effect of superoxide, hydroxyl and bromine free radicals on enzyme activity; Int. J. Radiant. Biol. 37 213-217
21. Sozmen E Y, Sozmen B, Delen Y and Onat T 2001 Catalase/superoxide dismutase (SOD) and catalase/paraoxonase (PON) ratios may implicate poor glycemic control; Arch. Med. Res. 32 283-287
22. Sunderman F W Jr, Marzouk A, Hopfer S M, Zaharia O and Reid M C 1985 Increased lipid peroxidation in tissues of nickel chloride-treated rats; Ann. Clin. Lab. Sci. 15 229-236
23. Uchimura K, Nagasaka A, Hayashi R, Makino M, Nagata M, Kakizawa H, Kobayashi T, Fujiwara K, Kato T, Iwase K, Shinohara R, Kato K and Itoh M 1999 Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus; J. Diabet. Complications 13 264-270
24. Ukeda H, Maeda S, Ishii T and Sawamura M 1997 Spectrophotometric assay for superoxide dismutase based on tetrazolium salt 3′-{1-(phenylamino)-carbonyl-3,4-tetrazolium}-bis (4-methoxy-6-nitro) benzenesulfonic acid hydrate reduction by xanthine-xanthine oxidase; Anal. Biochem. 251 206-209
25. Wolff S P, Jiang Z Y and Shunt J V 1991 Protein glycation and oxidative stress in diabetes mellitus and aging; Free Rad. Biol. Med. 10 339-352