메뉴 건너뛰기




Volumn 2, Issue 1, 2008, Pages 11-20

Human papillomavirus association with head and neck cancers: Understanding virus biology and using it in the development of cancer diagnostics

Author keywords

Biomarkers; E6; E7; Head and neck cancer; HPV; Human papillomavirus

Indexed keywords

PROTEIN E6; PROTEIN E7;

EID: 77953460750     PISSN: 17530059     EISSN: 17530067     Source Type: Journal    
DOI: 10.1517/17530059.2.1.11     Document Type: Review
Times cited : (9)

References (90)
  • 1
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • Zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2002;2(5):342-350 (Pubitemid 37328947)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.5 , pp. 342-350
    • Zur Hausen, H.1
  • 2
    • 0028937867 scopus 로고
    • Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells
    • Jeon S, Allen-Hoffmann BL, Lambert PF. Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells. J Virol 1995;69(5):2989-2997
    • (1995) J Virol , vol.69 , Issue.5 , pp. 2989-2997
    • Jeon, S.1    Allen-Hoffmann, B.L.2    Lambert, P.F.3
  • 3
    • 0021986880 scopus 로고
    • Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
    • DOI 10.1038/314111a0
    • Schwarz E, Freese UK, Gissmann L, et al. Structure and transcription of human papillomavirus sequences in cervical carcinoma cells. Nature 1985;314(6006):111-114 (Pubitemid 15142033)
    • (1985) Nature , vol.314 , Issue.6006 , pp. 111-114
    • Schwarz, E.1    Freese, U.F.2    Gissmann, L.3
  • 4
    • 0021821058 scopus 로고
    • Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines
    • Yee C, Krishnan-Hewlett I, Baker CC, Schlegel R, Howley PM. Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol 1985;119(3):361-366 (Pubitemid 15051884)
    • (1985) American Journal of Pathology , vol.119 , Issue.3 , pp. 361-366
    • Yee, C.1    Krishnan-Hewlett, I.2    Baker, C.C.3
  • 7
    • 34248350674 scopus 로고    scopus 로고
    • Case-control study of human papillomavirus and oropharyngeal cancer
    • This case-control study demonstrates that high-risk sexual behaviour, exposure to HPV and HPV infection increase the risk for HNSCC
    • D'souza G, Kreimer AR, Viscidi R, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 2007;356(19):1944-56 •• This case-control study demonstrates that high-risk sexual behaviour, exposure to HPV and HPV infection increase the risk for HNSCC.
    • (2007) N Engl J Med , vol.356 , Issue.19 , pp. 1944-1956
    • D'Souza, G.1    Kreimer, A.R.2    Viscidi, R.3
  • 8
    • 10044248559 scopus 로고    scopus 로고
    • Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity
    • DOI 10.1053/j.seminoncol.2004.09.011, PII S0093775404004087, Head and Neck Cancer
    • Gillison ML. Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity. Semin Oncol 2004;31(6):744-754 (Pubitemid 39602680)
    • (2004) Seminars in Oncology , vol.31 , Issue.6 , pp. 744-754
    • Gillison, M.L.1
  • 9
    • 34247379040 scopus 로고    scopus 로고
    • Human papillomavirus and prognosis of oropharyngeal squamous cell carcinoma: Implications for clinical research in head and neck cancers
    • DOI 10.1200/JCO.2006.07.1829
    • Gillison ML. Human papillomavirus and prognosis of oropharyngeal squamous cell carcinoma: implications for clinical research in head and neck cancers. J Clin Oncol 2006;24(36):5623-5625 (Pubitemid 46631299)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.36 , pp. 5623-5625
    • Gillison, M.L.1
  • 11
    • 28444485665 scopus 로고    scopus 로고
    • Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: A population-based case-control study in southern Sweden
    • DOI 10.1080/00016480510043945, PII R27331480X
    • Hansson BG, Rosenquist K, Antonsson A, et al. Strong association between infection with human papillomavirus and oral and oropharyngeal squamous cell carcinoma: a population-based case-control study in southern Sweden. Acta Otolaryngol 2005;125(12):1337-1344 (Pubitemid 41722001)
    • (2005) Acta Oto-Laryngologica , vol.125 , Issue.12 , pp. 1337-1344
    • Hansson, B.G.1    Rosenquist, K.2    Antonsson, A.3    Wennerberg, J.4    Schildt, E.-B.5    Bladstrom, A.6    Andersson, G.7
  • 13
    • 28444469433 scopus 로고    scopus 로고
    • Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern Sweden
    • Rosenquist K, Wennerberg J, Schildt EB, et al. Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern Sweden. Acta Otolaryngol 2005;125(12):1327-1336
    • (2005) Acta Otolaryngol , vol.125 , Issue.12 , pp. 1327-1336
    • Rosenquist, K.1    Wennerberg, J.2    Schildt, E.B.3
  • 17
    • 0034036090 scopus 로고    scopus 로고
    • Changing patterns of tonsillar squamous cell carcinoma in the United States
    • DOI 10.1023/A:1008918223334
    • Frisch M, Hjalgrim H, Jaeger AB, Biggar RJ. Changing patterns of tonsillar squamous cell carcinoma in the United States. Cancer Causes Control 2000;11(6):489-495 (Pubitemid 30342838)
    • (2000) Cancer Causes and Control , vol.11 , Issue.6 , pp. 489-495
    • Frisch, M.1    Hjalgrim, H.2    Jaeger, A.B.3    Biggar, R.J.4
  • 19
    • 2442428503 scopus 로고    scopus 로고
    • HPV infections and tonsillar carcinoma
    • DOI 10.1136/jcp.2003.008656
    • Syrjanen S. HPV infections and tonsillar carcinoma. J Clin Pathol 2004;57(5):449-455 (Pubitemid 38621787)
    • (2004) Journal of Clinical Pathology , vol.57 , Issue.5 , pp. 449-455
    • Syrjanen, S.1
  • 20
    • 0026794201 scopus 로고
    • Human papillomavirus (HPV) type 16 and 33 E6/E7 region transcripts in tonsillar carcinomas can originate from integrated and episomal HPV DNA
    • Snijders PJ, Meijer CJ, Van Den Brule AJ, et al. Human papillomavirus (HPV) type 16 and 33 E6/E7 region transcripts in tonsillar carcinomas can originate from integrated and episomal HPV DNA. J Gen Virol 1992;73(Pt 8):2059-2066
    • (1992) J Gen Virol , vol.73 , Issue.PART 8 , pp. 2059-2066
    • Snijders, P.J.1    Meijer, C.J.2    Van Den Brule, A.J.3
  • 22
    • 0037058306 scopus 로고    scopus 로고
    • Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer
    • DOI 10.1002/ijc.10669
    • Mellin H, Dahlgren L, Munck-Wikland E, et al. Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer. Int J Cancer 2002;102(2):152-8 • Demonstrates that HPV positivity in HNSCC is a positive prognostic factor. (Pubitemid 35168028)
    • (2002) International Journal of Cancer , vol.102 , Issue.2 , pp. 152-158
    • Mellin, H.1    Dahlgren, L.2    Munck-Wikland, E.3    Lindholm, J.4    Rabbani, H.5    Kalantari, M.6    Dalianis, T.7
  • 23
    • 8644249908 scopus 로고    scopus 로고
    • Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients
    • Demonstrates that HPV positivity in HNSCC is a positive prognostic factor
    • Dahlgren L, Dahlstrand HM, Lindquist D, et al. Human papillomavirus is more common in base of tongue than in mobile tongue cancer and is a favorable prognostic factor in base of tongue cancer patients. Int J Cancer 2004;112(6):1015-9 • Demonstrates that HPV positivity in HNSCC is a positive prognostic factor.
    • (2004) Int J Cancer , vol.112 , Issue.6 , pp. 1015-1019
    • Dahlgren, L.1    Dahlstrand, H.M.2    Lindquist, D.3
  • 25
    • 33645506107 scopus 로고    scopus 로고
    • Evidence of human papilloma virus infection and its epidemiology in esophageal squamous cell carcinoma
    • Yao PF, Li GC, Li J, et al. Evidence of human papilloma virus infection and its epidemiology in esophageal squamous cell carcinoma. World J Gastroenterol 2006;12(9):1352-1355
    • (2006) World J Gastroenterol , vol.12 , Issue.9 , pp. 1352-1355
    • Yao, P.F.1    Li, G.C.2    Li, J.3
  • 28
    • 0026692663 scopus 로고
    • Prevalence and expression of human papillomavirus in tonsillar carcinomas, indicating a possible viral etiology
    • Snijders PJ, Cromme FV, Van Den Brule AJ, et al. Prevalence and expression of human papillomavirus in tonsillar carcinomas, indicating a possible viral etiology. Int J Cancer 1992;51(6):845-850
    • (1992) Int J Cancer , vol.51 , Issue.6 , pp. 845-850
    • Snijders, P.J.1    Cromme, F.V.2    Van Den Brule, A.J.3
  • 29
    • 0037444398 scopus 로고    scopus 로고
    • Is the p53 inactivation frequency in squamous cell carcinomas of the head and neck underestimated? Analysis of p53 exons 2-11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor specimens
    • Balz V, Scheckenbach K, Gotte K, et al. Is the p53 inactivation frequency in squamous cell carcinomas of the head and neck underestimated? Analysis of p53 exons 2-11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor specimens. Cancer Res 2003;63(6):1188-1191 (Pubitemid 36348693)
    • (2003) Cancer Research , vol.63 , Issue.6 , pp. 1188-1191
    • Balz, V.1    Scheckenbach, K.2    Gotte, K.3    Bockmuhl, U.4    Petersen, I.5    Bier, H.6
  • 30
    • 33751038688 scopus 로고    scopus 로고
    • 11q13 amplification status and human papillomavirus in relation to p16 expression defines two distinct etiologies of head and neck tumours
    • DOI 10.1038/sj.bjc.6603394, PII 6603394
    • Ragin CC, Taioli E, Weissfeld JL, et al. 11q13 amplification status and human papillomavirus in relation to p16 expression defines two distinct etiologies of head and neck tumours. Br J Cancer 2006;95(10):1432-1438 (Pubitemid 44760098)
    • (2006) British Journal of Cancer , vol.95 , Issue.10 , pp. 1432-1438
    • Ragin, C.C.R.1    Taioli, E.2    Weissfeld, J.L.3    White, J.S.4    Rossie, K.M.5    Modugno, F.6    Gollin, S.M.7
  • 33
    • 85047700479 scopus 로고    scopus 로고
    • Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRB cell cycle control
    • DOI 10.1038/sj/onc/1205214
    • Wiest T, Schwarz E, Enders C, Flechtenmacher C, Bosch FX. Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control. Oncogene 2002;21(10):1510-1517 (Pubitemid 34226138)
    • (2002) Oncogene , vol.21 , Issue.10 , pp. 1510-1517
    • Wiest, T.1    Schwarz, E.2    Enders, C.3    Flechtenmacher, C.4    Bosch, F.X.5
  • 35
    • 0031974324 scopus 로고    scopus 로고
    • Detection of human papillomavirus DNA and oncoprotein overexpression are associated with distinct morphological patterns of tonsillar squamous cell carcinoma
    • Wilczynski SP, Lin BT, Xie Y, Paz IB. Detection of human papillomavirus DNA and oncoprotein overexpression are associated with distinct morphological patterns of tonsillar squamous cell carcinoma. Am J Pathol 1998;152(1):145-156 (Pubitemid 28028055)
    • (1998) American Journal of Pathology , vol.152 , Issue.1 , pp. 145-156
    • Wilczynski, S.P.1    Lin, B.T.-Y.2    Xie, Y.3    Paz, I.B.4
  • 37
    • 32944464047 scopus 로고    scopus 로고
    • Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma
    • Demonstrates distinct transcriptional patterns associated with HPV-positive HNSCC
    • Slebos RJ, Yi Y, Ely K, et al. Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma. Clin Cancer Res (2006)12(3 Pt 1):701-9 •• Demonstrates distinct transcriptional patterns associated with HPV-positive HNSCC.
    • (2006) Clin Cancer Res , vol.12 , Issue.3 PART 1 , pp. 701-709
    • Slebos, R.J.1    Yi, Y.2    Ely, K.3
  • 38
    • 0034690490 scopus 로고    scopus 로고
    • Human papilloma virus (HPV) DNA in tonsillar cancer: Clinical correlates, risk of relapse, and survival
    • DOI 10.1002/1097-0215(20000520)89:3<300::AID-IJC14>3.0.CO;2-G
    • Mellin H, Friesland S, Lewensohn R, Dalianis T, Munck-Wikland E. Human papillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival. Int J Cancer 2000;89(3):300-304 (Pubitemid 30430748)
    • (2000) International Journal of Cancer , vol.89 , Issue.3 , pp. 300-304
    • Mellin, H.1    Friesland, S.2    Lewensohn, R.3    Dalianis, T.4    Munck-Wikland, E.5
  • 40
    • 0344237142 scopus 로고    scopus 로고
    • A new link between Fanconi anemia and human papillomavirus-associated malignancies
    • Lowy DR, Gillison ML. A new link between Fanconi anemia and human papillomavirus-associated malignancies. J Natl Cancer Inst 2003;95(22):1648-1650 (Pubitemid 37509065)
    • (2003) Journal of the National Cancer Institute , vol.95 , Issue.22 , pp. 1648-1650
    • Lowy, D.R.1    Gillison, M.L.2
  • 42
    • 77953379548 scopus 로고    scopus 로고
    • The life cycle of human papillomaviruses in keratinocytes
    • DiMaio RLGaD, editor, Springer Science, New York
    • Laimins CLAL. The life cycle of human papillomaviruses in keratinocytes. In: The Papillomaviruses . DiMaio RLGaD, editor, Springer Science, New York; 2007. p. 45-67
    • (2007) The Papillomaviruses , pp. 45-67
    • Laimins, C.L.A.L.1
  • 43
    • 0025932933 scopus 로고
    • A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
    • Huibregtse JM, Scheffner M, Howley PM. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J 1991;10(13):4129-4135 (Pubitemid 21905444)
    • (1991) EMBO Journal , vol.10 , Issue.13 , pp. 4129-4135
    • Huibregtse, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 44
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • DOI 10.1016/0092-8674(93)90384-3
    • Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993;75(3):495-505 (Pubitemid 23335075)
    • (1993) Cell , vol.75 , Issue.3 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 45
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteins with p53
    • Werness BA, Levine AJ, Howley PM. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science 1990;248(4951):76-79 (Pubitemid 20139274)
    • (1990) Science , vol.248 , Issue.4951 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 46
    • 0035956258 scopus 로고    scopus 로고
    • Biological activities and molecular targets of the human papillomavirus E7 oncoprotein
    • DOI 10.1038/sj/onc/1204860
    • Munger K, Basile JR, Duensing S, et al. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene 2001;20(54):7888-7898 (Pubitemid 33135315)
    • (2001) Oncogene , vol.20 , Issue.54 REV. ISS. 7 , pp. 7888-7898
    • Munger, K.1    Basile, J.R.2    Duensing, S.3    Eichten, A.4    Gonzalez, S.L.5    Grace, M.6    Zacny, V.L.7
  • 47
    • 0022644639 scopus 로고
    • E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene
    • Schiller JT, Vass WC, Vousden KH, Lowy DR. E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene. J Virol 1986;57(1):1-6 (Pubitemid 16147910)
    • (1986) Journal of Virology , vol.57 , Issue.1 , pp. 1-6
    • Schiller, J.T.1    Vass, W.C.2    Vousden, K.H.3    Lowy, D.R.4
  • 48
    • 0033740178 scopus 로고    scopus 로고
    • Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways
    • DOI 10.1073/pnas.97.23.12513
    • Goodwin EC, Dimaio D. Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways. Proc Natl Acad Sci USA 2000;97(23):12513-12518 (Pubitemid 30840447)
    • (2000) Proceedings of the National Academy of Sciences of the United States of America , vol.97 , Issue.23 , pp. 12513-12518
    • Goodwin, E.C.1    Dimaio, D.2
  • 51
    • 0023352068 scopus 로고
    • Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells
    • Matlashewski G, Schneider J, Banks L, et al. Human papillomavirus type 16 DNA cooperates with activated ras in transforming primary cells. EMBO J 1987;6(6):1741-1746
    • (1987) EMBO J , vol.6 , Issue.6 , pp. 1741-1746
    • Matlashewski, G.1    Schneider, J.2    Banks, L.3
  • 52
    • 0024292712 scopus 로고
    • The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A
    • Phelps WC, Yee CL, Munger K, Howley PM. The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell 1988;53(4):539-547
    • (1988) Cell , vol.53 , Issue.4 , pp. 539-547
    • Phelps, W.C.1    Yee, C.L.2    Munger, K.3    Howley, P.M.4
  • 53
    • 0026489720 scopus 로고
    • Sequential combined tumorigenic effect of HPV-16 and chemical carcinogens
    • Li SL, Kim MS, Cherrick HM, Doniger J, Park NH. Sequential combined tumorigenic effect of HPV-16 and chemical carcinogens. Carcinogenesis 1992;13(11):1981-1987
    • (1992) Carcinogenesis , vol.13 , Issue.11 , pp. 1981-1987
    • Li, S.L.1    Kim, M.S.2    Cherrick, H.M.3    Doniger, J.4    Park, N.H.5
  • 54
    • 0031010967 scopus 로고    scopus 로고
    • HPV-16 oncogenes E6 and E7 are mutagenic in normal human oral keratinocytes
    • Liu X, Han S, Baluda MA, Park NH. HPV-16 oncogenes E6 and E7 are mutagenic in normal human oral keratinocytes. Oncogene 1997;14(19):2347-2353 (Pubitemid 27260727)
    • (1997) Oncogene , vol.14 , Issue.19 , pp. 2347-2353
    • Liu, X.1    Han, S.2    Baluda, M.A.3    Park, N.-H.4
  • 55
    • 0029027669 scopus 로고
    • Combined oral carcinogenicity of HPV-16 and benzo(a)pyrene: An in vitro multistep carcinogenesis model
    • Park NH, Gujuluva CN, Baek JH, et al. Combined oral carcinogenicity of HPV-16 and benzo(a)pyrene: an in vitro multistep carcinogenesis model. Oncogene 1995;10(11):2145-2153
    • (1995) Oncogene , vol.10 , Issue.11 , pp. 2145-2153
    • Park, N.H.1    Gujuluva, C.N.2    Baek, J.H.3
  • 57
    • 0030064068 scopus 로고    scopus 로고
    • Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene
    • Herber R, Liem A, Pitot H, Lambert PF. Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene. J Virol 1996;70(3):1873-1881 (Pubitemid 26062951)
    • (1996) Journal of Virology , vol.70 , Issue.3 , pp. 1873-1881
    • Herber, R.1    Liem, A.2    Pitot, H.3    Lambert, P.F.4
  • 58
    • 0033028610 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals
    • Song S, Pitot HC, Lambert PF. The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals. J Virol 1999;73(7):5887-5893 (Pubitemid 29274875)
    • (1999) Journal of Virology , vol.73 , Issue.7 , pp. 5887-5893
    • Song, S.1    Pitot, H.C.2    Lambert, P.F.3
  • 59
    • 0042440926 scopus 로고    scopus 로고
    • Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis
    • Riley RR, Duensing S, Brake T, et al. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res 2003;63(16):4862-4871 (Pubitemid 37022618)
    • (2003) Cancer Research , vol.63 , Issue.16 , pp. 4862-4871
    • Riley, R.R.1    Duensing, S.2    Brake, T.3    Munger, K.4    Lambert, P.F.5    Arbeit, J.M.6
  • 60
    • 0034652546 scopus 로고    scopus 로고
    • Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis
    • DOI 10.1006/viro.1999.0106
    • Song S, Liem A, Miller JA, Lambert PF. Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis. Virology 2000;267(2):141-150 (Pubitemid 30123597)
    • (2000) Virology , vol.267 , Issue.2 , pp. 141-150
    • Song, S.1    Liem, A.2    Miller, J.A.3    Lambert, P.F.4
  • 61
    • 33749039168 scopus 로고    scopus 로고
    • Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model
    • DOI 10.1073/pnas.0606698103
    • Strati K, Pitot HC, Lambert PF. Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model. Proc Natl Acad Sci USA 2006;103(38):14152-14157 (Pubitemid 44452995)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.38 , pp. 14152-14157
    • Strati, K.1    Pitot, H.C.2    Lambert, P.F.3
  • 62
  • 63
    • 0025194133 scopus 로고
    • 6-adenine adducts formed by 4-nitroquinoline 1-oxide blocks the 3'-5' exonuclease action of T4 DNA polymerase
    • Panigrahi GB, Walker IG. The N2-guanine adduct but not the C8-guanine or N6-adenine adducts formed by 4-nitroquinoline 1-oxide blocks the 3′-5′ exonuclease action of T4 DNA polymerase. Biochemistry 1990;29(8):2122-2126 (Pubitemid 20085440)
    • (1990) Biochemistry , vol.29 , Issue.8 , pp. 2122-2126
    • Panigrahi, G.B.1    Walker, I.G.2
  • 64
    • 0032555508 scopus 로고    scopus 로고
    • A yeast homologue of the human phosphotyrosyl phosphatase activator PTPA is implicated in protection against oxidative DNA damage induced by the model carcinogen 4-nitroquinoline 1-oxide
    • DOI 10.1074/jbc.273.34.21489
    • Ramotar D, Belanger E, Brodeur I, Masson JY, Drobetsky EA. A yeast homologue of the human phosphotyrosyl phosphatase activator PTPA is implicated in protection against oxidative DNA damage induced by the model carcinogen 4-nitroquinoline 1-oxide. J Biol Chem 1998;273(34):21489-21496 (Pubitemid 28405316)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.34 , pp. 21489-21496
    • Ramotar, D.1    Belanger, E.2    Brodeur, I.3    Masson, J.-Y.4    Drobetsky, E.A.5
  • 65
    • 1642453724 scopus 로고    scopus 로고
    • Oral Cavity and Esophageal Carcinogenesis Modeled in Carcinogen-Treated Mice
    • DOI 10.1158/1078-0432.CCR-0999-3
    • Tang XH, Knudsen B, Bemis D, Tickoo S, Gudas LJ. Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. Clin Cancer Res. 2004;10(1 Pt 1):301-313 (Pubitemid 38114193)
    • (2004) Clinical Cancer Research , vol.10 , Issue.1 , pp. 301-313
    • Tang, X.-H.1    Knudsen, B.2    Bemis, D.3    Tickoo, S.4    Gudas, L.J.5
  • 66
    • 0028943318 scopus 로고
    • Relative genotoxic activities of pesticides evaluated by a modified SOS microplate assay
    • Venkat JA, Shami S, Davis K, et al. Relative genotoxic activities of pesticides evaluated by a modified SOS microplate assay. Environ Mol Mutagen 1995;25(1):67-76
    • (1995) Environ Mol Mutagen , vol.25 , Issue.1 , pp. 67-76
    • Venkat, J.A.1    Shami, S.2    Davis, K.3
  • 67
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • DOI 10.1038/387296a0
    • Haupt Y, Maya R, Kazaz A, OREN M. Mdm2 promotes the rapid degradation of p53. Nature 1997;387(6630):296-299 (Pubitemid 27220766)
    • (1997) Nature , vol.387 , Issue.6630 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 68
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • DOI 10.1038/387299a0
    • Kubbutat MH, Jones SN, Vousden KH. Regulation of p53 stability by Mdm2. Nature 1997;387(6630):299-303 (Pubitemid 27220767)
    • (1997) Nature , vol.387 , Issue.6630 , pp. 299-303
    • Kubbutat, M.H.G.1    Jones, S.N.2    Vousden, K.H.3
  • 69
    • 0027079358 scopus 로고
    • The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein
    • Mietz JA, Unger T, Huibregtse JM, Howley PM. The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein. EMBO J 1992;11(13):5013-5020 (Pubitemid 23023445)
    • (1992) EMBO Journal , vol.11 , Issue.13 , pp. 5013-5020
    • Mietz, J.A.1    Unger, T.2    Huibregtse, J.M.3    Howley, P.M.4
  • 70
    • 33847743738 scopus 로고    scopus 로고
    • The human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities
    • DOI 10.1158/0008-5472.CAN-06-3344
    • Shai A, Brake T, Somoza C, Lambert PF. The human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities. Cancer Res 2007;67(4):1626-1635 (Pubitemid 46383388)
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1626-1635
    • Shai, A.1    Brake, T.2    Somoza, C.3    Lambert, P.F.4
  • 71
    • 24944485818 scopus 로고    scopus 로고
    • Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential
    • DOI 10.1158/0008-5472.CAN-05-1651
    • Simonson SJ, Difilippantonio MJ, Lambert PF. Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential. Cancer Res 2005;65(18):8266-8273 (Pubitemid 41330591)
    • (2005) Cancer Research , vol.65 , Issue.18 , pp. 8266-8273
    • Simonson, S.J.S.1    Difilippantonio, M.J.2    Lambert, P.F.3
  • 72
    • 27744438456 scopus 로고    scopus 로고
    • Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle
    • DOI 10.1128/JVI.79.23.14769-14780.2005
    • Collins AS, Nakahara T, Do A, Lambert PF. Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle. J Virol 2005;79(23):14769-14780 (Pubitemid 41636275)
    • (2005) Journal of Virology , vol.79 , Issue.23 , pp. 14769-14780
    • Collins, A.S.1    Nakahara, T.2    Do, A.3    Lambert, P.F.4
  • 73
    • 0026550131 scopus 로고
    • Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses
    • Heck DV, Yee CL, Howley PM, Munger K. Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proc Natl Acad Sci USA 1992;89(10):4442-4446
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.10 , pp. 4442-4446
    • Heck, D.V.1    Yee, C.L.2    Howley, P.M.3    Munger, K.4
  • 74
    • 0025815414 scopus 로고
    • Biochemical and biological differences between E7 oncoproteins of the high- And low-risk human papillomavirus types are determined by amino-terminal sequences
    • Munger K, Yee CL, Phelps WC, et al. Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences. J Virol 1991;65(7):3943-3948
    • (1991) J Virol , vol.65 , Issue.7 , pp. 3943-3948
    • Munger, K.1    Yee, C.L.2    Phelps, W.C.3
  • 75
    • 37549062918 scopus 로고    scopus 로고
    • Role of Rb-dependent and independent functions of papillomavirus E7 oncogene in head and neck cancer
    • Strati K, Lambert PF. Role of Rb-dependent and independent functions of papillomavirus E7 oncogene in head and neck cancer. Cancer Res 2008;67(24):11585-11593
    • (2008) Cancer Res , vol.67 , Issue.24 , pp. 11585-11593
    • Strati, K.1    Lambert, P.F.2
  • 76
    • 34447129574 scopus 로고    scopus 로고
    • Human papillomavirus 16 E5 oncogene contributes to two stages of skin carcinogenesis
    • DOI 10.1158/0008-5472.CAN-07-0921
    • Maufort JP, Williams SM, Pitot HC, Lambert PF. Human papillomavirus 16 E5 oncogene contributes to two stages of skin carcinogenesis. Cancer Res 2007;67(13):6106-6112 (Pubitemid 47037490)
    • (2007) Cancer Research , vol.67 , Issue.13 , pp. 6106-6112
    • Maufort, J.P.1    Genther Williams, S.M.2    Pitot, H.C.3    Lambert, P.F.4
  • 78
    • 0026586144 scopus 로고
    • The E5 gene from human papillomavirus type 16 is an oncogene which enhances growth factor-mediated signal transduction to the nucleus
    • Leechanachai P, Banks L, Moreau F, Matlashewski G. The E5 gene from human papillomavirus type 16 is an oncogene which enhances growth factor-mediated signal transduction to the nucleus. Oncogene 1992;7(1):19-25
    • (1992) Oncogene , vol.7 , Issue.1 , pp. 19-25
    • Leechanachai, P.1    Banks, L.2    Moreau, F.3    Matlashewski, G.4
  • 79
    • 0026593192 scopus 로고
    • Human papillomavirus type 16 E5 gene stimulates the transforming activity of the epidermal growth factor receptor
    • Pim D, Collins M, Banks L. Human papillomavirus type 16 E5 gene stimulates the transforming activity of the epidermal growth factor receptor. Oncogene 1992;7(1):27-32
    • (1992) Oncogene , vol.7 , Issue.1 , pp. 27-32
    • Pim, D.1    Collins, M.2    Banks, L.3
  • 80
    • 33748188459 scopus 로고    scopus 로고
    • Epidermal growth factor receptor biology in head and neck cancer
    • DOI 10.1200/JCO.2005.04.8306
    • Kalyankrishna S, Grandis JR. Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 2006;24(17):2666-2672 (Pubitemid 46622088)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.17 , pp. 2666-2672
    • Kalyankrishna, S.1    Grandis, J.R.2
  • 83
    • 22144437747 scopus 로고    scopus 로고
    • Comparison between the hybrid capture II test and a PCR-based human papillomavirus detection method for diagnosis and posttreatment follow-up of cervical intraepithelial neoplasia
    • DOI 10.1128/JCM.43.7.3260-3266.2005
    • Soderlund-Strand A, Rymark P, Andersson P, Dillner J, Dillner L. Comparison between the Hybrid Capture II test and a PCR-based human papillomavirus detection method for diagnosis and posttreatment follow-up of cervical intraepithelial neoplasia. J Clin Microbiol 2005;43(7):3260-3266 (Pubitemid 40981333)
    • (2005) Journal of Clinical Microbiology , vol.43 , Issue.7 , pp. 3260-3266
    • Soderlund-Strand, A.1    Rymark, P.2    Andersson, P.3    Dillner, J.4    Dillner, L.5
  • 84
    • 35648937953 scopus 로고    scopus 로고
    • A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen
    • Demonstrates that biomarker staining in addition to HPV DNA testing in tumor samples increases specificity over individual screening methods
    • Smeets SJ, Hesselink AT, Speel EJ, et al. A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen. Int J Cancer 2007;121(11):2465-72 •• Demonstrates that biomarker staining in addition to HPV DNA testing in tumor samples increases specificity over individual screening methods.
    • (2007) Int J Cancer , vol.121 , Issue.11 , pp. 2465-2472
    • Smeets, S.J.1    Hesselink, A.T.2    Speel, E.J.3
  • 85
    • 0031740497 scopus 로고    scopus 로고
    • Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
    • Sano T, Oyama T, Kashiwabara K, Fukuda T, Nakajima T. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 1998;153(6):1741-1748 (Pubitemid 28550662)
    • (1998) American Journal of Pathology , vol.153 , Issue.6 , pp. 1741-1748
    • Sano, T.1    Oyama, T.2    Kashiwabara, K.3    Fukuda, T.4    Nakajima, T.5
  • 86
    • 0347626104 scopus 로고    scopus 로고
    • Comparative Analysis of Cervical Cancer in Women and in a Human Papillomavirus-Transgenic Mouse Model: Identification of Minichromosome Maintenance Protein 7 as an Informative Biomarker for Human Cervical Cancer
    • Brake T, Connor JP, Petereit DG, Lambert PF. Comparative analysis of cervical cancer in women and in a human papillomavirus-transgenic mouse model: identification of minichromosome maintenance protein 7 as an informative biomarker for human cervical cancer. Cancer Res 2003;63(23):8173-8180 (Pubitemid 37549465)
    • (2003) Cancer Research , vol.63 , Issue.23 , pp. 8173-8180
    • Brake, T.1    Connor, J.P.2    Petereit, D.G.3    Lambert, P.F.4
  • 87
    • 34247179521 scopus 로고    scopus 로고
    • MCM immunocytochemistry as a first line cervical screening test in developing countries: A prospective cohort study in a regional cancer centre in India
    • DOI 10.1038/sj.bjc.6603679, PII 6603679
    • Mukherjee G, Muralidhar B, Bafna UD, Laskey RA, Coleman N. MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India. Br J Cancer 2007;96(7):1107-1111 (Pubitemid 46608320)
    • (2007) British Journal of Cancer , vol.96 , Issue.7 , pp. 1107-1111
    • Mukherjee, G.1    Muralidhar, B.2    Bafna, U.D.3    Laskey, R.A.4    Coleman, N.5
  • 89
    • 0032417029 scopus 로고    scopus 로고
    • In vivo cyclin E expression as a marker for early cervical neoplasia
    • Quade BJ, Park JJ, Crum CP, Sun D, Dutta A. In vivo cyclin E expression as a marker for early cervical neoplasia. Mod Pathol 1998;11(12):1238-1246
    • (1998) Mod Pathol , vol.11 , Issue.12 , pp. 1238-1246
    • Quade, B.J.1    Park, J.J.2    Crum, C.P.3    Sun, D.4    Dutta, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.