Expressions of TP and HIF-1α in gastric carcinoma tissues and their correlations with prognosis

Chinese Journal of Cancer Prevention and Treatment

Volumn 16, Issue 17, 2009, Pages 1315-1319

  Zhou, Li Hao ^a   Li, Lin Hu ^b   Li, Ge ^b  

^a Liu'an People's Hospital   (China)

^b YANBIAN UNIVERSITY   (China)

Author keywords

Hypoxia inducible factor 1 ; Immunohistochemistry; Prognosis; Stomach neoplasms pathology; Thymidine phosphorylase

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; THYMIDINE PHOSPHORYLASE;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER PATIENT; CANCER SIZE; CANCER STAGING; CANCER TISSUE; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PROGNOSIS; PROTEIN EXPRESSION; STOMACH CARCINOMA; SURVIVAL RATE;

EID: 77953460145     PISSN: 16735269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Jang J S, Lee W S, Lee J S, et al. The expression of thymidine phosphorylase in cancer-infiltrating inflammatory cells in stomach cancer [J]. J Korean Med Sci, 2007, 22(Suppl): 109-114.
2. Kandil M A, El-Wahed M M, El-Tahmody M, et al. Predictive value of thymidine Phosphorylase in gastric carcinoma [J]. Egypt Natl Canc Inst, 2004, 16(3): 159-167.
3. Hua D, Huang Z H, Mao Y, et al. Thymidyiate synthase and thymidine Phosphorylase gene expression as predictive parameters for the efficacy of 5-fluorouraci-based adjuvant chemotherapy for gastric cancer [J]. World J Gastroenterol, 2007, 13(37): 5030-5034. (Pubitemid 47496839)
4. Griffiths L, Dachs G U, Bicknell R, et al. The angiogenic factor, platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo [J]. Cancer Res, 1997, 57(4): 570-572. (Pubitemid 27085632)
5. Kabuubi P, Loncaster J A, Davidson S E, et al. No relationship between thymidine Phosphorylase (TP, PD-ECGF) expression and hypoxia in carcinoma of the cervix [J]. Br J Cancer, 2006, 94(1): 115-120. (Pubitemid 43088550)
6. Tan E Y, Campo L, Han C, et al. Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer [J]. Breast Cancer Res, 2007, 9(6): 89.
7. Ikeda R. Molecular basis for the inhibition of anticancer agents-induced apoptosis by thymidine phosphorylase [J]. Yakugaku Zasshi, 2007, 127(7): 1097-1102. (Pubitemid 47035641)
8. van Triest B, Pinedo H M, Blaauwgeers J L, et al. Prognostic role of thymidyiate synthase, thymridine phosphorylase/platelet derived endothelial cell growth factor, and proliferation markers, in colorectal cancer [J]. Clin Cancer Res, 2000, 6(3): 1063-1072.
9. Saito H, Tsujitani S, Oka S, et al. The expression of thymidine Phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma [J]. Br J Cancer, 1999, 81(3): 484-489. (Pubitemid 29458803)
10. Zhong H, de Marzoa M, Laughner E, et al. Overexpression of hypoxia-inducible factor 1 alpha in common human cancers and their metastases [J]. Cancer Res, 1999, 59(22): 5830-5835.
11. Urano N, Fujiwara Y, Doki Y, et al. Overexpression of hypoxia inducible factor-1 alpha in gastric adenocarcinoma [J]. Gastric Cancer, 2006, 9(1): 44-49.
12. Brown N S, Streeter E H, Jones A. Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma [J]. Br J Cancer, 2005, 92(9): 1696-1701. (Pubitemid 40756481)