Design and evaluation of controlled release chitosan-calcium alginate microcapsules of anti tubercular drugs for oral use

International Journal of ChemTech Research

Volumn 2, Issue 1, 2010, Pages 88-98

  Sabitha, P ^a   Vijaya Ratna, J ^b   Ravindra Reddy, K ^a  

^a P Rami Reddy Memorial College of Pharmacy   (India)

^b ANDHRA UNIVERSITY   (India)

Author keywords

Bioavailability; Chitosan; Controlled release; Microcapsules; Sodium alginate

Indexed keywords

CALCIUM ALGINATE; CHITOSAN DERIVATIVE; ISONIAZID; PYRAZINAMIDE; RIFAMPICIN;

ACIDITY; ALKALINITY; ARTICLE; BIODEGRADABILITY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DETERMINATION; DRUG FORMULATION; DRUG PURITY; DRUG SCREENING; GELATION; IN VITRO STUDY; LUNG TUBERCULOSIS; MICROCAPSULE; MUCOADHESION; PH; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE;

EID: 77953452459     PISSN: None     EISSN: 09744290     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Burman W.J; Cohn D.L; Rietmeijer, C.A; Judson F.N; Sbarbaro J.A; Reves R., Noncompliance with directly observed therapy for tuberculosis. Epidemiology and effect on the outcome of treatment, Chest ,1997, 111, 1168-1173.
2. Pandey R; Zahoor A; Sharma S ; Khuller G.K, Nanoparticle encapsulated antitubercular drugs as a potential oral drug delivery system against murine tuberculosis, Tuberculosis (Edinb) ,2003, 83, 373-378.
3. Ain, Q.U; Sharma, S; Khuller, G.K; Garg, S.K, Alginate-based oral drug delivery system for tuberculosis: pharmacokinetic and therapeutic effects, J Antimicrob Chemother ,2003, 51, 931-938.
4. Labana, S; Pandey, R, Sharma, S; Khuller, G.K, Chemotherapeutic activity against murine tuberculosis of once weekly administered drugs (INH and RIF) encapsulated in liposomes, Int J Antimicrob Agents,.2002, 20, 301-304.
5. Bala, I; Harihaan, S; Ravi Kumar, M.N.V, PLGA nanoparticles in drug delivery: the state of the art, Crit Rev Ther Drug Carrier Syst,2004, 21, 387-422.
6. Shah, S.P and Misra, A, Development of liposomal amphotericin B dry powder inhaler formulation, Drug Deliv ,2004, 11, 247-253.
7. Hurley,L and Andersen, B.R. Biodegradable implants from poly-(alpha-hydroxy acid) polymers for isoniazid delivery, Int J Tuberc Lung Dis ,1999, 3, 1015-1024.
8. Jacobs, C and Muller, R.H. Production and characterization of a budesonide nanosuspension for pulmonary administration, Pharm Res .2002, 19,189-194.
9. Quenelle, D. C; Winchester, G. A; Staas, J. K. Treatment of tuberculosis using a combination of sustained-release rifampin-loaded microspheres and oral dosing with isoniazi,. Antimicrobial Agents and Chemotherapy, 2001, 45, 1637-44.
10. Ain, Q; Sharma, S; Khuller, G. K. Role of poly (DL-lactide-co-glycolide) in development of sustained oral delivery systems for antitubercular drug(s), International Journal of Pharmaceutics , 2002, 239, 37-46.
11. Ain, Q; Sharma, S; Khuller, G. K. Chemotherapeutic potential of orally administered poly (lactide-co-glycolide) microparticles containing isoniazide, rifampicin and pyrazinamide against experimental tuberculosis, Antimicrobial Agents and Chemotherapy .2003, 4, 3005-7.
12. Tonnesen, H. H; Karlsen, J. Alginate in drug delivery systems. Drug Development and Industrial Pharmacy, 2002, 28, 621-30.
13. Hejazi, R; Amiji, M. Chitosan-based gastrointestinal delivery systems. Journal of Controlled Release, 2003, 89, 151-65.
14. Charles, S. L; Chioo, Joseph, R; Robinson. Remington. The sciences and practice of pharmacy. Sustained release drug delivery systems; Mark publishing company, Pennsylvania, 1995, pp-1660-1675
15. Leon Lachmann, Herbert A .Lieberman, Joseph L. Kanig. The theory and practice of industrial pharmacy, Sustained release dosage form, Varghese publishing House (Bombay), 1987.
16. Gombotz, W.R; Wee, S.F. Protein release from alginate matrices, Adv. Drug Deliv. Rev, 1998, 31,267-285
17. Murata, Y; Maeda, T; Miyamoto, E; Kawashima, S. Preparation of chitosan-reinforced alginate gel beads - effects of chitosan on gel matrix erosion, Int J Pharm. 1993, 96, 139 - 145.
18. Takahashi, T; Takayama, K; Machida, Y; Nagai, T. Characteristics of polyion complexes of chitosan with sodium alginate and sodium polyacrylate, Int J Pharm,.1990, 61, 35 - 41.
19. Artursson, P; Lindmark, T; Davis, S.S; Illum, L. Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2), Pharm Re. 1994, 11, 1358 - 1361.
20. Illum, L; Farraj, N.F; Davis, S.S. Chitosan as a novel nasal delivery system for peptide drugs, Pharm Res, 1994, 11,1186-1189.
21. Lueben, H; Lehr, C.M; Rentel, C.O. Bioadhesive polymers for the per oral delivery of peptide drugs, J Control Releas, 1994, 29, 329 - 338.
22. González-Rodríguez, M.L; Holgado, M.A; Sánchez- Lafuente, C; Rabasco , A.M; Fini, A .Alginate/chitosan particulate systems for sodium diclofenac release, International Journal of Pharmaceutics ,2002, 232,225-234.
23. Volland Wolff, M; Kissel, T. The influence of terminal gamma sterilization of captropril containing poly [D, L-lactide-co-glycolide] microcapsules, J. Control. Release,1994, 31,293-305.
24. Bhumkar DR. Studies on Effect of Variabilities by response Surface Methodology for Naproxane microspheres, Indian Drugs, 2003, 40 (8), 455-461.
25. Debjit Bhowmik, B; Jayakar. Formulation and evaluation of hydroxy propyl cellulose microspheres of Metformin Hcl, The Pharma Review,2008, 6(36), 140-142.
26. Gohel MC. Preparation and formulation optimization of sugar cross linking gelatin microspheres of diclofenac sodium, Indian J. Pharm. Sci, 2005, 67, 575-581.
27. Chowdary, K.P.R; Sambasiva Rao, K.R.S; Koteswara Rao, N. Design of EVA microcapsules of glipizide for controlled release: Influence of solvents use, Int. J. Chem. Sci.2006, 4(1), 23-30.
28. Parul Trivedi, A.M.L; Verma, N; Garud. Preparation and characterization of aceclofenac microspheres, Asian journal of pharmaceutical, 2008, 2(2), 110-115
29. Anil K. Anal, Willem, F; Stevens. Chitosan-alginate multilayer beads for controlled release of ampicillin,.International Journal of Pharmaceutics,2005, 290, 45-54
30. Parodi,B; Russo, E; Caviglioli, G; Cafaggi, S; Bignardi, G. Development and characterization of a buccoadhesive dosage form of oxycodone hydrochloride, Drug Dev Ind Pharm, 1996, 22,445-450.
31. Lehr, C.M; Bowstra, J.A; Tkker, J.J; Jnginer, H.E. Intestinal transit of bioadhesive microspheres in an in situ loop in the rat, J. Control Release,1990, 13, 51-62.
32. Rao, B.S and Murthy, K.V.R,Development of dissolution medium for the rifampicin sustained release formulation, Indian. J. pharm. Sci, 2001, 63(3), 258-260.
33. Higuchi T, Mechanism of sustained action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices, J. Pharm. Sci, 1963, 51, 1145-1149.
34. Peppas N.A, Analysis of Fickian and Non-Fickian drug release from polymers,Pharm. Acta. Helv, 1985, 60,110-111.
35. Ravi Kumar, M. N. V, Nano and microparticles as controlled drug delivery devices. Journal of Pharmacy and Pharmaceutical Sciences .2000, 3, 234-58.
36. Gaserod, O; Smidsrod, O; Skjak-Braek, G, Microcapsules of alginate/chitosan - I: A quantitative study of the interaction between alginate and chitosan biomaterials,1998, 19, 1815-1825.
37. Drevin, G.R and Vincent, 1.Granulometric determination of sedimentary rock particle roundness http://www.cmis.csiro.au/ismm2002/proceedings/pdf/28- drevin.pdf
38. Lim, L.Y; Wan, L.S.C; Thai, P.Y, Chitosan microspheres prepared by emulsification and ionotropic gelation, Drug Dev.Ind. Pharm.1997, 23, 981-985.
39. Sezer, A.D and Akbuga, J. Controlled release of piroxicam from chitosan beads,Int.J. Pharm,1995, 121, 113-116.
40. Anal, A.K; Bhopatkar, D; Tokura, S; Tamura, H; Stevens, W.F, Chitosan-alginate multilayer beads for gastric passage and controlled intestinal release of protein, Drug Dev. Ind.Pharm.2003, 29, 713-724
41. Sriamornsak, P and Kennedy, R. A, Swelling and diffusion studies of calcium polysaccharide gels intended for film coating, International Journal of Pharmaceutics. 2008, 358(1-2), 205-213.
42. Huang, Y; Leobandung, W; Foss, A; Peppas, N.A, Molecular aspects of muco- and bioadhesion: tethered structures and site-specific surfaces, J. Control. Release ,2000, 65, 63-71.
43. Ostberg, T; Lund, E.M; Graffner, C, Calcium alginate matrices for oral multiple unit administration. IV. Release characteristics in different media, Int J Pharm , 1994,112, 241 - 248.
44. Murata, Y; Maeda, T; Miyamoto, E; Kawashima, S, Preparation of chitosan-reinforced alginate gel beads - effects of chitosan on gel matrix erosion, Int J Pharm. 1993, 96, 139 - 145.