Role of poly [DL-lactide-co-glycolide] in development of a sustained oral delivery system for antitubercular drug(s)

International Journal of Pharmaceutics

Volumn 239, Issue 1-2, 2002, Pages 37-46

  Ain, Q ^a   Sharma, S ^a   Garg, S K ^a   Khuller, G K ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Antitubercular drugs; Oral drug delivery; PLG

Indexed keywords

ISONIAZID; POLYGLACTIN; PYRAZINAMIDE; RIFAMPICIN; TUBERCULOSTATIC AGENT;

ACIDITY; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG ELIMINATION; DRUG FORMULATION; FEMALE; IN VITRO STUDY; INTESTINE FLUID; MALE; NONHUMAN; PRIORITY JOURNAL; STOMACH JUICE; SUSTAINED DRUG RELEASE; TIME; TUBERCULOSIS;

ADMINISTRATION, ORAL; ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; ANTITUBERCULAR AGENTS; AREA UNDER CURVE; BIOCOMPATIBLE MATERIALS; CAPSULES; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; FEMALE; HALF-LIFE; ISONIAZID; LACTIC ACID; MALE; MICE; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; PYRAZINAMIDE; RIFAMPIN; SOLUBILITY;

EID: 0037018964     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00034-0     Document Type: Article

References (16)

1. Tuberculosis today
2. Intestinal absorption of PLAGA microspheres in the rat
3. Therapeutic efficacy of poly (DL-lactide-co-glcolide) encapsulated antitubercular drugs against Mycobacterium tuberculosis infection induced in mice
4. Chemotherapy of Mycobacterium tuberculosis infection in mice with a combination of isoniazid and rifampicin entrapped in poly (DL-lactideo-co-glycolide) microparticles
5. Large porous particles for pulmonary drug delivery
6. Sustained release of isoniazid in vivo from a biodegradable polymer implant
7. Methods of estimation of pyrazinamide and pyrazonioic acid in body fluids
8. Biodegradable microspheres in drug delivery
9. Chitosan/calcium alginate microcapsules for intestinal delivery of nitrofurantoin
10. Maintenance of therapeutically active levels of INH for prolonged periods in rabbits after a single implant of biodegradable polymer
11. Release of fluorcscent marker prodan from poly (DL-lactide-acid) nanoparticles coated with albumin or polyvinyl alcohol in model digestive fluids
12. Biologically erodable microspheres as potential oral drug delivery systems
13. One month release injectable microspheres of leuprorelin acetate using biodegradable polymers
14. Poly (palmitoyl-L-hydroxyproline ester) microspheres as potential oral controlled drug delivery systems
15. Therapeutic efficacy of liposome entrapped rifampicin against Mycobacterium avium complex infections induced in mice
16. Fluorimetric determination of isonicotinic acid hydrazide in serum