Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain

Journal of Innate Immunity

Volumn 2, Issue 3, 2010, Pages 267-279

  White, Mitchell R ^a   Boland, Patrick ^a   Tecle, Tesfaldet ^a   Gantz, Donald ^a   Sorenson, Grith ^c   Tornoe, Ida ^c   Holmskov, Uffe ^c   McDonald, Barbara ^b   Crouch, Erika C ^b   Hartshorn, Kevan L ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Influenza virus; Neutrophils; Surfactant protein D

Indexed keywords

CARBOHYDRATE; COLLECTIN; CONGLUTININ; IMMUNOGLOBULIN FC FRAGMENT; MANNOSE BINDING LECTIN; MONOCLONAL ANTIBODY; SURFACTANT PROTEIN D; VITRONECTIN;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; HEMAGGLUTINATION; HUMAN; HUMAN CELL; MUTAGENESIS; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; RESPIRATORY BURST; VIRUS ATTACHMENT;

ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; COLLECTINS; CROSS-LINKING REAGENTS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; IMMUNITY, INNATE; IMMUNOGLOBULIN FRAGMENTS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; MACROPHAGES; MUTAGENESIS, SITE-DIRECTED; NEUTROPHILS; PROTEIN ENGINEERING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; RECOMBINANT FUSION PROTEINS;

EID: 77953435887     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000272313     Document Type: Article

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