Alcohol extract of Pterogyne nitens leaves fails to reduce severity of streptozotocin-induced diabetes in rats

Journal of Medicinal Plants Research

Volumn 4, Issue 9, 2010, Pages 802-808

  de Souza, Aline ^a   Vendramini, Regina C ^a   Brunetti, Iguatemy L ^a   Regasini, Luis O ^a   Siqueira Silva, Dulce H ^a   Bolzani, Vanderlan Silva ^a   Pepato, Maria T ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Alkaline phosphatase; Antidiabetic plant; Biochemical markers; Hepato biliary toxicity marker

Indexed keywords

ALCOHOL; ANTIDIABETIC AGENT; GLYCEROL; INSULIN; PLANT EXTRACT; PTEROGYNE NITENS EXTRACT; UNCLASSIFIED DRUG; UREA;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; GLUCOSURIA; MALE; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; PROTEIN URINE LEVEL; PROTEINURIA; PTEROGYNE NITENS; RAT; STREPTOZOCIN DIABETES;

GLYCERINE; PTEROGYNE NITENS; RATTUS;

EID: 77953405032     PISSN: 19960875     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Allen Jr LV, Popovich NG, Ansel HC (2007). Formas farmacêuticas e sistemas de liberação de fármacos. 8 ed, Artmed, Porto Alegre pp. 372.
2. Arkkila PET, Koskinen PJ, Kantola IM, Ronnemaa T, Seppanen E, Viikari JS (2001). Diabetes complications associated with liver enzyme activities in people with type 1 diabetes mellitus. Diabetes Res. Clin. Pract. 52: 113-118.
3. Bailey CJ, Day C (2004). Metformin: its botanical background. Pract. Diab. Int. 21: 115-117.
4. Benigni R, Capra C, Cattorini PE (1964). Plante medicinali, chimica farmacologia e terapia. Inverni Della Beta, Milão, pp. 626-632.
5. Bergemeyer HU (1985). Methods of Enzymatic Analysis. Volume 9, VHC, Florida, pp. 449-453.
6. Bolleter WT, Bushman CJ, Tidwell PW (1961). Spectrophotometric determination of ammonia as indophenol. Anal. Chem. 33: 592-594.
7. Bradford MM (1976). A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72: 248-254.
8. Brunetti IL, Vendramini RC, Januário AH, Franga SC, Pepato MT (2006). Effects and toxicity of Eugenia punicifolia extracts in streptozotocin-diabetic rats. Pharm. Biol. 44: 35-43.
9. Crivos M, Martinez MR, Pochettino MI, Remorini C, Si A, Teves A (2007). Pathways as ''signatures in landscape'': towards an ethnography of mobility among the Mbya-Guarani (Northeastern Argentina). J. Ethnobiol. Ethnomed. 3: 1-12.
10. Dubowski KM (1962). An o-toluidine method for body fluid glucose determination. Clin. Chem. 8: 215-235.
11. Felig P, Bergaman M (1995). The endocrine pancreas: diabetes mellitus. In Felig P, Baxter JD, Frohman LA (eds) Endocrinolgy and Metabolism, McGraw-Hill, New York pp. 1107-1250.
12. Grover JK, Vats V, Rathi SS (2000). Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J. Ethnopharmacol. 73: 461-470.
13. Hall M (2003). Carbohydrates. In Anderson SC, Cockayne S (eds) Clinical Chemistry - concepts & applications, McGraw-Hill, New York pp. 153-178.
14. Hamden K, Allouch N, Damak M, Elfeki A (2009). Hypoglycemic and antioxidant effects of phenolic extracts and purified hydroxytyrosol from olive mill waste in vitro and in rats. Chem. Biol. Interact. 180: 421-432.
15. 14C-glucose uptake in rat soleus muscle. Chem. Biol. Interact. 149: 89-96.
16. Lorenzi H (1998). Árvores Brasileiras: Manual de Identificação e Cultivo de Plantas Arbóreas do Brasil. Plantarum, Nova Odessa.
17. Mori DM, Baviera AM, Ramalho LTO, Vendramini RC, Brunetti IL, Pepato MT (2003). Temporal response pattern of biochemical analytes in experimental diabetes. Biotechnol. Appl. Bichem. 18: 183-191.
18. Oliveira DM, Freitas HS, Souza MFF, Argari DP, Ribeiro MI, Carvalho PO, Bastos DHM (2008). Yerba Maté (Ilex paraguariensis) aqueous extract decrease intestinal SGLT1 gene expression but does not affect other biochemical parameters in alloxan-diabetic Wistar rats. J. Agric. Food. Chem. 56: 10527- 10532.
19. Pepato MT, Baviera AM, Vendramini RC, Brunetti IL (2004). Evaluation of toxicity after one-months treatment with Bauhinia forficata decoction in streptozotocin-diabetc rats. BMC Complement Altern. Med. 4: 1-7.
20. Pepato MT, Baviera AM, Vendramini RC, Perez MPMS, Kettelhut IC, Brunetti IL (2003). Cissus sicyoides (princess vine) in the long-term treatment of streptozotocin-diabetic rats. Biotechnol. Appl. Biochem. 37: 15-20.
21. Pepato MT, Folgado VBB, Kettelhut IC, Brunetti IL (2001). Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes. Braz. J. Med. Biol. Res. 34: 389-395.
22. Pepato MT, Keller EH, Baviera AM, Kettelhut IC, Vendramini RC, Brunetti IL (2002). Anti-diabetic activity of Bauhinia forficata decotion on streptozotocin-diabetic rats. J. Ethnopharmacol. 81: 191-197.
23. Pepato MT, Mori DM, Baviera AM, Harami JB, Vendramini RC, Brunetti IL (2005). Fruit of the jambolan tree (Eugenia jambolana Lam.) and experimetnal diabetes. J. Ethnopharmacol. 96: 43-48.
24. Pepato MT, Oliveira JR, Kettelhut IC, Migliorini RH (1993). Assessment of the antidiabetic activity of Myrcia uniflora extracts in streptozotocin diabetic rats. Diab. Res. 22: 49-57.
25. Pizzolatti MG, Cunha Jr A, Szpoganicz B, Souza E, Braz-Filho R, Schripsema J (2003). Flavonoids glycosides from leaves and flowers of Bauhinia forficata (Leguminosae). Química Nova 26: 466-469.
26. Prince PS, Menon VP, Pari L (1998). Hypoglycaemic activity of Syzigium cumini seeds: effect on lipid peroxidation in alloxan diabetic rats. J. Ethnopharmacol. 61: 1-7.
27. Rauter AP, Martins A, Lopes R, Ferreira J, Serralheiro LM, Araújo ME, Borges C, Justino J, Silva FV, Goulart M, Thomas-Oates J, Rodrigues J, Edwards E, Noronha JP (2009). Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera. J. Ethnopharmacol. 122: 384-393.
28. Regasini LO, Castro-Gamboa I. Silva DHS, Furlan M, Barreiro EJ, Ferreira PMP, Pessoa C, Lotufo LVC, Moraes MO, Young MCM, Bolzani VS (2009). Cytotoxic guanidine alkaloids from Pterogyne nitens. J. Nat. Prod. 72: 473-476.
29. Regasini LO, Vellosa JCR, Silva DHS, Furlan M, Oliveira OMM, Khalil NM, Brunetti IL, Young M.M, Barreiro EJ, Bolzani VS (2008). Flavonols from Pterogyne nitens and their evaluation as myeloperoxidase inhibotors. Phytochemistry 69:1739-1744.
30. Reuter G (1963). Arginin als Vorstufe von Galegin in Galega officinalis. Arch. Pharm. 296: 516-522.
31. Setacci C, Donato G, Setacci F, Chisci E (2009). Diabetic patients: epidemiology and global impact. Cardiovas. Sur. (Torino) 50: 263-273.
32. Souza A, Vendramini RC, Brunetti IL, Regasini LO, Bolzani VS, Silva SHS, Pepato MT (2009). Continuous treatment with alcohol extract from Pterogyne nitens leaves does not alter typical variables of experimental diabetes. Braz. J. Pharmacol. 19: 412-417.
33. Souza E, Zanatta L, Seifriz I, Creczynski-Pasa TB, Pizzolatti MG, Szpoganicz B, Silva FRMB (2004). Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(α)-dirhamnoside from Bauhinia forficata leaves. J. Nat. Prod. 67: 829-832.
34. The Expert Committee on the Diagnosis and Classification of Diabetes mellitus (2003). Report of the Expert Committee on the Diagnosis and Classification of Diabetes mellitus. Diab. Care 26: S5-S20.
35. Viana GSB, Medeiros AC, Lacerda AMR, Leal LKAM, Vale TG, Matos JA (2004). Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides. BMC Pharmacology 4: 9. About 7 p.
36. Viberti G, Wiseman MJ, Pinto JR, Messent J (1994). Diabetic nephropathy. In Kahn CR, Weir GC (eds) Joslin' Diabetes mellitus, Lea and Febiger - Waverly Company, Malvern pp. 691-637.