Chronic delta hepatitis: An overview

Hepatitis B Annual

Volumn 5, Issue 1, 2008, Pages 81-94

  Yurdaydin, Cihan ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Delta hepatitis; Epidemiology; Hepatitis D virus; Natural history; Treatment; Virology.

Indexed keywords

ADEFOVIR; ALPHA INTERFERON; ANTIVIRUS AGENT; CLEVUDINE; FAMCICLOVIR; INTERFERON; LAMIVUDINE; NUCLEOSIDE ANALOG; PEGINTERFERON; PEGINTERFERON ALPHA; PRENYLATION INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL THERAPY; CHEMOTHERAPY; CHRONIC HEPATITIS; CLINICAL FEATURE; CLINICAL TRIAL; DELTA AGENT HEPATITIS; DISEASE COURSE; DRUG MEGADOSE; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS DELTA VIRUS; HUMAN; INFECTION RATE; MIGRATION; MIXED INFECTION; MONOTHERAPY; NONHUMAN; PATHOPHYSIOLOGY; PATIENT COMPLIANCE; REVERSE TRANSCRIPTION; REVIEW; RNA REPLICATION; SEQUENCE ANALYSIS; SUPERINFECTION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; VIRUS CARRIER; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS TRANSMISSION;

EID: 77953390120     PISSN: 09729747     EISSN: 19983573     Source Type: Journal    
DOI: 10.4103/0972-9747.58807     Document Type: Review

References (50)

1. Rizzetto M, Canese MG, Arico S, Crivelli O, Trepo C, Bonino F, et al. Immunofl uorescence detection of new antigen-antibody system (delta/anti-delta) associated to hepatitis B virus in liver and in serum of HBsAg carriers. Gut 1977;18:997-1003.
2. Smedile A, Rizetto M, Gerin JL. Advances in hepatitis D virus biology and disease. Prog Liver Dis 1994;12:157-175
3. Koytak ES, Yurdaydin C, Glenn JS. Hepatitis D. Curr Treat Options Gastroenterol 2007;10:456-463
4. Farci P. Delta hepatitis: An update. J Hepatol 2003;39:S212-9.
5. Radjef N, Gordien E, Ivaniushina V, Gault E, Anais P, Drugan T, et al. Molecular phylogenetic analyses indicate a wide and ancient radiation of African hepatitis delta virus, suggesting a delta virus genus of at least seven major clades. J Virol 2004;78:2537-2544
6. Shakil AO, Hadziyannis S, Hoofnagle JH, Di Bisceglie AM, Gerin JL, Casey JL. Geographic distribution and genetic variability of hepatitis delta virus genotype I. Virology 1997;234:160-167
7. Wu JC, Choo KB, Chen CM, Chen TZ, Huo TI, Lee SD. Genotyping of hepatitis D with restriction-fragment length polymorphism and relation to outcome of hepatitis D. Lancet 1995;346:939-941
8. Sakugawa H, Nakasone H, Nakayoshi T, Kawakami Y, Miyazato S, Kinjo F, et al. Hepatitis delta virus genotype IIb predominates in an endemic area, Okinawa, Japan. J Med Virol 1999;58:366-372
9. Watanabe H, Nagayama K, Enomoto N, Chinzei R, Yamashiro T, Izumi N, et al. Chronic hepatitis delta virus infection with genotype IIb variant is correlated with progressive liver disease. J Gen Virol 2003; 84:3275-3289
10. Casey JL, Niro GA, Engle RE, Vega A, Gomez H, McCarthy M, et al. Hepatitis B virus (HBV)/hepatitis D virus (HDV) coinfection in outbreaks of acute hepatitis in the Peruvian Amazon Basin: The roles of genotype III and HBV genotype F. J Infect Dis 1996;174:920-926
11. Hoofnagle JH. Type D hepatitis. JAMA 1989;261:1321-1325
12. Sagnelli E, Stroffolini T, Ascione A, Chiaramonte M, Craxì A, Giusti G, et al. Decrease in HDV endemicity in Italy. J Hepatol 1997;26:20-24
13. Gaeta GB, Stroffolini T, Chiaramonte M, Ascione T, Stornaiuolo G, Lobello S, et al. A vanishing disease? An Italian Multicenter Study. Hepatology 2000;32:824-827
14. Hadziyannis SJ, Dourakis SP, Papaioannou C, Alexopoulou A, Hadziyannis ES, Gioustozi A. Changing epidemiology and spreading modalities of hepatitis delta virus infection in Greece. Prog Clin Biol Res 1993;382:259-266
15. Huo TI, Wu JC, Lin RY, Sheng WY, Chang FY, Lee SD. Decreasing hepatitis D virus infection in Taiwan: An analysis of contributory factors. J Gastroenterol Hepatol 1997;12:747-751
16. Erhardt A, Knuth R, Sagir A, Kirschberg O, Heintges T, Haussinger D. Socio-epidemiological data on hepatitis delta in a German university clinic-increase in patients from Eastern Europe and the former Soviet Union. Z Gastroenterol 2003;41:523-526
17. Wedemeyer H, Heidrich B, Manns MP. Hepatitis D virus infection-not a vanishing disease in Europe. Hepatology 2007;45:1331-1332
18. Gaeta GB, Stroffolini T, Smedile A, Niro G, Mele A. Hepatitis delta in Europe: Vanishing or refreshing? Hepatology 2007;46:1312-1313
19. Deǧertekin H, Yalçin K, Yakut M, Yurdaydin C. Seropositivity for delta hepatitis in patients with chronic hepatitis B and liver cirrhosis in Turkey: A meta-analysis. Liver Int 2008;28:494-498
20. Yurdaydin C. Delta hepatitis in Turkey: Decreasing but not vanishing and still of concern. Turk J Gastroenterol 2006;17:74-75
21. Guilhot S, Huang SS, Xia YP, La Monica N, Lai MM, Chisari FV. Expression of hepatitis delta virus large and small antigens in transgenic mice. J Virol 1994;68:1052-1058
22. Nisini R, Paroli M, Accapezzato D, Bonino F, Rosina F, Santantonio T, Sallusto F, et al. Human CD4+ T-cell response to hepatitis delta virus: ?dentifi cation of multiple epitopes and characterization of T-helper cytokine profi les. J Virol 1997;71:2241-2251
23. Aslan N, Yurdaydin C, Wiegand J, Greten T, Ciner A, Meyer MF, et al. Cytotoxic CD4+ T cells in viral hepatitis. J Viral Hepat 2006;13:505-514
24. Fattovich G, Giustina G, Christensen E, Pantalena M, Zagni I, Realdi G, et al. Influence of hepatitis delta virus infection on morbidity and mortality in compensated cirrhosis type B. The European Concerted Action on Viral Hepatitis (Eurohep). Gut 2000;46:420-426
25. Rosina F, Conoscitore P, Cuppone R, Rocca G, Giuliani A, Cozzolongo R, et al. Changing pattern of chronic hepatitis D in Southern Europe. Gastroenterology 1999;117:161-166
26. Samuel D, Muller R, Alexander G, Fassati L, Ducot B, Benhamou JP, et al. Liver transplantation in European patients with the hepatitis B surface antigen. N Engl J Med 1993; 329:1842-1847
27. Smedile A, Casey JL, Cote PJ, Durazzo M, Lavezzo B, Purcell RH, et al. Hepatitis D viremia following orthotopic liver transplantation involves a typical HDV virion with a hepatitis B surface antigen envelope. Hepatology 1998;27:1723-1729
28. Farci P, Mandas A, Coiana A, Lai ME, Desmet V, Van Eyken P, et al. Treatment of chronic hepatitis D with interferon alfa-2a. N Engl J Med 1994;330:88-94.
29. Madejon A, Cotonat T, Bartolome J, Castillo I, Carreno V. Treatment of chronic hepatitis D virus infection with low and high doses of interferon-alpha 2a: Utility of polymerase chain reaction in monitoring antiviral response. Hepatology 1994;19:1331-1336
30. Gaudin JL, Faure P, Godinot H, Gerard F, Trepo C. The French experience of treatment of chronic type D hepatitis with a 12-month course of interferon alpha-2B: Results of a randomized controlled trial. Liver 1995;15:45-52.
31. Farci P, Roskams T, Chessa L, Peddis G, Mazzoleni AP, Scioscia R, et al. Long-term benefi t of interferon alpha therapy of chronic hepatitis D: Regression of advanced hepatic fi brosis. Gastroenterology 2004;126:1740-1749
32. Lau DT, Kleiner DE, Park Y, Di Bisceglie AM, Hoofnagle JH. Resolution of chronic delta hepatitis after 12 years of interferon alfa therapy. Gastroenterology 1999;117:1229-1233
33. Di Marco V, Giacchino R, Timitilli A, Bortolotti F, Crivellaro C, Calzia R, et al. Long-term interferon-alfa treatment of children with chronic hepatitis delta: A multicentre study. J Viral Hepat 1996;3:123-128
34. Yurdaydin C, Bozkaya H, Karaaslan H, Onder FO, Erkan OE, Yalcin K, et al. A pilot study of two years of interferon in patients with chronic delta hepatitis. J Viral Hepat 2007;14:812-816
35. Gunsar F, Akarca US, Ersoz G, Kobak AC, Karasu Z, Yuce G, et al. Two-year interferon therapy with or without ribavirin in chronic delta hepatitis. Antivir Ther 2005;10:721-726
36. Niro GA, Ciancio A, Gaeta GB, Smedile A, Marrone A, Olivero A, et al. Pegylated interferon alpha-2b as monotherapy or in combination with ribavirin in chronic hepatitis delta. Hepatology 2006;44:713-720
37. Erhardt A, Gerlich W, Starke C, Wend U, Donner A, Sagir A, et al. Treatment of chronic hepatitis delta with pegylated interferon-alpha2b. Liver Int 2006;26:805-810
38. Castelnau C, Le Gal F, Ripault MP, Gordien E, Martinot-Peignoux M, Boyer N, et al. Efficacy of peginterferon alpha-2b in chronic hepatitis delta: Relevance of quantitative RT-PCR for follow-up. Hepatology 2006;44:728-735
39. Wedemeyer H, Yurdaydin C, Dalekos G, Erhardt A, Cakaloglu Y, Degertekin H, et al. 72 week data of the HIDIT-1 trial: Multicenter randomized study comparing peginterferon α-2a plus adefovir vs. peginterferon α-2a plus placebo vs. adefovir in chronic delta hepatitis. J Hepatology 2007;46:S4
40. Yurdaydin C, Bozkaya H, Onder FO, Sentürk H, Karaaslan H, Akdoǧan M, et al. Treatment of chronic delta hepatitis with lamivudine vs. lamivudine + interferon vs. interferon. J Viral Hepat 2008:15:314-321
41. Lau DT, Doo E, Park Y, Kleiner DE, Schmid P, Kuhns MC, et al. Lamivudine for chronic delta hepatitis. Hepatology 1999;30:546-549
42. Niro GA, Ciancio A, Tillman HL, Lagget M, Olivero A, Perri F, et al. Lamivudine therapy in chronic delta hepatitis: A multicentre randomized-controlled pilot study. Aliment Pharmacol Ther 2005;22:227-232
43. Yurdaydin C, Bozkaya H, Gürel S, Tillmann HL, Aslan N, Okçu-Heper A, et al. Famciclovir treatment of chronic delta hepatitis. J Hepatol 2002;37:266-271
44. Peek SF, Cota PJ, Jacob JR, Toshkov IA, Hornbuckle WE, Baldwin BH, et al. Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-β, L-arabinofuranosyluracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax). Hepatology 2001;33:254-266
45. Casey J, Cote PJ, Toshkov IA, Chu CK, Gerin JL, Hornbuckle WE, et al. Clevudine inhibits hepatitis delta virus viremia: A pilot study of chronically infected woodchucks. Antimicrob Agents Chemother 2005;49:4396-4399
46. Glenn JS, Watson JA, Havel CM, White JM. Identification of a prenylation site in delta virus large antigen. Science 1992;256:1331-1333
47. Glenn JS, Marsters JC Jr, Greenberg HB. Use of a prenylation inhibitor as a novel antiviral agent. J Virol 1998;72:9303-9306
48. Bordier BB, Marion PL, Ohashi K, Kay MA, Greenberg HB, Casey JL, et al. A prenylation inhibitor prevents production of infectious hepatitis delta virus particles. J Virol 2002;76:10465-10472
49. Bordier BB, Ohkanda J, Liu P, Lee SY, Salazar FH, Marion PL, et al. In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus. J Clin Invest 2003;112:407-414
50. Rowinsky EK, Windle JJ, Von Hoff DD. Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development. J Clin Oncol 1999;17:3631-3652