Diagnosis and treatment of cerebral vasculitis

Therapeutic Advances in Neurological Disorders

Volumn 3, Issue 1, 2010, Pages 29-42

  Berlit, Peter ^a  

^a ALFRIED KRUPP KRANKENHAUS   (Germany)

Author keywords

angiitis; angiography; antibodies; giant cell arteritis; immunosuppressants; steroids; stroke; Vasculitis

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA INTERFERON; AZATHIOPRINE; C REACTIVE PROTEIN; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; ETANERCEPT; FLUORODEOXYGLUCOSE F 18; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INFLIXIMAB; LAMIVUDINE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NEUTROPHIL CYTOPLASMIC ANTIBODY; PLACEBO; PREDNISOLONE; PREDNISONE; RIBAVIRIN; RITUXIMAB; STEROID;

ANGIOGRAPHY; AORTA ARCH SYNDROME; BEHCET DISEASE; BLOOD VESSEL WALL; BRAIN DISEASE; BRAIN VASCULITIS; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID ANALYSIS; CHURG STRAUSS SYNDROME; CLINICAL TRIAL; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; DISEASE CLASSIFICATION; DRUG DOSE REDUCTION; DRUG MEGADOSE; ERYTHROCYTE SEDIMENTATION RATE; GIANT CELL ARTERITIS; HEADACHE; HEPATITIS B; HEPATITIS C; HUMAN; INFLAMMATION; LABORATORY TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYARTERITIS NODOSA; POSITRON EMISSION TOMOGRAPHY; PRIMARY ANGIITIS OF THE CENTRAL NERVOUS SYSTEM; PRIORITY JOURNAL; RARE DISEASE; REVIEW; STROKE; SYMPTOM; SYSTEMIC VASCULITIS; TEMPORAL ARTERITIS; WEGENER GRANULOMATOSIS;

EID: 77953370047     PISSN: 17562856     EISSN: None     Source Type: Journal    
DOI: 10.1177/1756285609347123     Document Type: Review

References (72)

1. Akman-Demir, G., Serdaroglu, P. and Tasci, B. ( 1999) Clinical patterns of neurological involvement in Behcet's disease: evaluation of 200 patients. The Neuro-Behcet Study Group. Brain 122: 2171-2182.
2. Alhalabi, M. and Moore, P.M. ( 1994) Serial angiography in isolated angiitis of the central nervous system. Neurology 44: 1221-1226.
3. Andrassy, K., Erb, A., Koderisch, J., Waldherr, R. and Ritz, E. ( 1991) Wegener's granulomatosis with renal involvement: patient survival and correlations between initial renal function, renal histology, therapy and renal outcome. Clin Nephrol 35: 139-147.
4. Andrews, J. and Mason, J.C. ( 2007) Takayasu's arteritis - recent advances in imaging offer promise. Rheumatology 46: 6-15.
5. Arend, W.P., Michel, B.A., Bloch, D.A., Hunder, G.G., Calabrese, L.H. and Edworthy, S.M. ( 1990) The American College of Rheumatology criteria for the classification of Takayasu arteritis. Arthritis Rheum 33: 1129-1134.
6. Barnes, C.G. ( 2006) Treatment of Behçet's syndrome. Rheumatology 45: 245-247.
7. Berlit, P. ( 2004a) Diagnosis and differential diagnosis of cerebral vasculitis. Nervenarzt 75: 105-112.
8. Berlit, P. ( 2004b) Cerebral vasculitis. Nervenarzt 75: 817-828.
9. Berlit, P., Stueper, B., Fink, I., Rebmann, V., Hoyer, P., Kreuzfelder, E. et al. (2005) Behcet's disease is associated with increased concentrations of antibodies against phosphatidylserine and ribosomal phosphoproteins. VASA J Vasc Dis 34: 176-180.
10. Berlit, P. ( 2007) Neuropsychiatric disease in collagen vascular diseases and vasculitis. J Neurol 254: 1187-89.
11. Berlit, P. ( 2009a) Primary angiitis of the CNS - an enigma that needs world-wide efforts to be solved. Eur J Neurol 16: 10-11.
12. Berlit, P. ( 2009b) The differential diagnosis of isolated angiitis of the CNS and bacterial endocarditis - similarities and differences. J Neurol 256: 792-795.
13. Bley, T.A., Uhl, M., Carew, J., Markl, M., Schmidt, D., Peter, H.H. et al. (2007) Diagnostic value of high-resolution MR imaging in giant cell arteritis. AJNR Am J Neuroradiol 28: 1722-1727.
14. Both, M., Ahmadi-Simab, K., Reuter, M., Dourvo, S.O., Fritzer, E., Ullrich, S. et al. (2008) MRI and FDG-PET in the assessment of inflammatory aortic arch syndrome in complicated courses of giant cell arteritis. Ann Rheum Dis 67: 1030-1033.
15. Bosch, X., Guilabert, A., Espinosa, G. and Mirapeix, E. ( 2007) Treatment of antineutrophil cytoplasmic antibody-associated vasculitis: a systematic review. JAMA 298: 655-669.
16. Cacoub, P., Maisonobe, T., Thibault, V., Gatel, A., Servan, J., Musset, L. et al. (2001) Systemic vasculitis in patients with hepatitis C. J Rheumatol 28: 109-118.
17. Calabrese, L.H., Dodic, K.D.W., Schwedt, T.J. and Singhal, A.B. ( 2007) Narrative review: reversible cerebral vasoconstriction syndromes. Ann Intern Med 146: 34-44.
18. Calabrese, L.H. and Mallek, J.A. ( 1987) Primary angiitis of the CNS: report of 8 new cases, review of the literature, and proposal for diagnostic criteria. Medicine 67: 20-37.
19. Chao, C.C., Hsieh, S.T., Shun, C.T. and Hsieh, S.C. ( 2007) Skin denervation and cutaneous vasculitis in eosinophilia-associated neuropathy. Arch Neurol 64: 959-965.
20. Chatelain, D., Duhaut, P., Schmidt, J., Loire, R., Bosshard, S., Guernou, M. et al. (2009) on behalf of the Groupe de Recherche sur l'Artérite à Cellules Géantes (GRACG). Pathological features of temporal arteries in patients with giant cell arteritis presenting with permanent visual loss. Ann Rheum Dis 68: 84-88.
21. Davies, L., Spies, J.M., Pollard, J.D. and McLeod, J.G. ( 1996) Vasculitis confined to peripheral nerves. Brain 119: 1441-1448.
22. Fauci, A.S., Haynes, B.F., Katz, P. and Wolff, S.M. ( 1983) Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med 98: 76-85.
23. Faurschou, M., Sorensen, I.J., Mellemkjaer, L., Rasmussen Loft, A.G., Thomsen, B.S., Tvede, N. et al. (2008) Malignancies in Wegener's granulomatosis: incidence and relation to cyclophosphamide therapy in a cohort of 293 patients. J Rheumatol 35: 100-105.
24. Gibson, A., Stamp, L.K., Chapman, P.T. and O'Donnell, J.L. ( 2006) The epidemiology of Wegener's granulomatosis and microscopic polyangiitis in a Southern Hemisphere region. Rheumatology 45: 624-628.
25. Grau, R.G. ( 2008) Churg-Strauss syndrome: 2005-2008 update. Curr Rheumatol Rep 10: 453-458.
26. Guillevin, L., Cordier, J.F., Lhote, F., Cohen, P., Jarrousse, B., Royer, I. et al. (1997) A prospective, multicenter, randomized trial comparing steroids and pulse cyclophosphamide versus steroids and oral cyclophosphamide in the treatment of generalized Wegener's granulomatosis. Arthritis Rheum 40: 2187-2198.
27. Hatemi, G., Silman, A., Bang, D., Bodaghi, B., Chamberlain, A.M., Gul, A. et al. (2008) EULAR recommendations for the management of Behçet disease. Ann Rheum Dis 67: 1656-1662.
28. Hayreh, S.S., Zimmerman, B. and Kardon, R.H. ( 2002) Visual improvement with corticosteroid therapy in giant cell arteritis. Report of a large study and review of literature. Acta Ophthalmol Scand 80: 355-367.
29. Hoffman, G.S., Cid, M.C., Hellmann, D.B., Guillevin, L., Stone, J.H., Schousboe, J. et al. (2002) A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritis. Arthritis Rheum 46: 1309-1318.
30. Hoffman, G.S., Cid, M.C., Rendt-Zagar, K.E., Merkel, P.A., Weyand, C.M., Stone, J.H. et al. (2007) for the Infliximab-GCA Study Group. Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis: a randomized trial. Ann Intern Med 146: 621-630.
31. Holder, S.M., Joy, M.S. and Falk, R.J. ( 2002) Cutaneous and systemic manifestations of drug-induced vasculitis. Ann Pharmacother 36: 130-147.
32. Hunder, G.G., Bloch, D.A., Michel, B.A., Stevens, M.B., Arend, W.P., Calabrese, L.H. et al. (1990) The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis. Arthritis Rheum 33: 1122-1128.
33. Jennette, J.C. and Falk, R.F. ( 2007) Nosology of primary vasculitis. Curr Opin Rheumatol 19: 10-16.
34. Jover, J.A., Hernandez-Garcia, C., Morado, I.C., Vargas, E., Banares, A. and Fernandez-Gutierrez, B. ( 2001) Combined treatment of giant-cell arteritis with methotrexate and prednisone. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 16: 106-114.
35. Keogh, K.A. and Specks, U. ( 2003) Churg-Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists. Am J Med 115: 284-290.
36. Keogh, K.A., Ytterberg, S.R., Fervenza, F.C., Carlson, K.A., Schroeder, D.R. and Specks, U. ( 2006) Rituximab for refractory Wegener's granulomatosis: Report of a prospective, open-label pilot trial. Am J Respir Crit Care Med 173: 180-187.
37. Khellaf, M., Hamidou, M., Pagnoux, C., Michel, M., Brisseau, J.M., Chevallier, X. et al. (2007) Vasculitis restricted to the lower limbs: a clinical and histopathological study. Ann Rheum Dis 66: 554-556.
38. Kumar, A. and Costa, D.D. ( 2007) Insidious posterior circulation stroke with rapid deterioration due to vertebral giant cell arteritis. Age Ageing 36: 695-697.
39. Knight, A., Askling, J., Granath, F., Sparen, P. and Ekbom, A. ( 2004) Urinary bladder cancer in Wegener's granulomatosis: risks and relation to cyclophosphamide. Ann Rheum Dis 63: 1307-1311.
40. Krämer, M., Heienbrok, W. and Berlit, P. ( 2008) Moyamoya disease in Europeans. Stroke 39: 3193-3200.
41. Lane, S.E., Watts, R.A., Shepstone, L. and Scott, D.G.I. ( 2005) Primary systemic vasculitis: clinical features and mortality. QJM 98: 97-111.
42. MacLaren, K., Gillespie, J., Shrestha, S., Neary, D. and Ballardie, F.W. ( 2005) Primary angiitis of the central nervous system: emerging variants. QJM 98: 643-654.
43. Makkuni, D., Bharadwaj, A., Wolfe, K., Payne, S., Hutchings, A. and Dasgupta, B. ( 2008) Is intimal hyperplasia a marker of neuro-ophthalmic complications of giant cell arteritis? Rheumatology 47: 488-490.
44. Martínez-Taboada, V.M., Rodríguez-Valverde, V., Carreno, L., López-Longo, J., Figueroa, M., Belzunegui, J. et al. (2008) A double-blind placebo controlled trial of etanercept in patients with giant cell arteritis and corticosteroid side effects. Ann Rheum Dis 67: 625-630.
45. Mirsattari, S.M., McGinn, G.J. and Halliday, W.C. ( 2004) Neuro-Behcet disease with predominant involvement of the brainstem. Neurology 63: 382-384.
46. Miyata, T., Sato, O., Koyama, H., Shigematsu, H. and Tada, Y. ( 2003) Long-term survival after surgical treatment of patients with Takayasu's arteritis. Circulation 108: 1474-1480.
47. Mohammad, A.J., Jacobsson, L.T.H., Mahr, A.D., Sturfelt, G. and Segelmark, M. ( 2007) Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden. Rheumatology 46: 1329-1337.
48. Molloy, E.S., Langford, C.A., Clark, T.M., Gota, C.E. and Hoffman, G.S. ( 2008) Anti-tumour necrosis factor therapy in patients with refractory Takayasu arteritis: long-term follow-up. Ann Rheumat Dis 67: 1567-1569.
49. Moore, P.M. ( 1989) Diagnosis and management of isolated angiitis of the central nervous system. Neurology 39: 167-173.
50. Mukhtyar, C., Flossmann, O., Hellmich, B., Bacon, P., Cid, M., Cohen-Tervaert, J.W. et al. (2008) and on behalf of the European Vasculitis Study Group (EUVAS). Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League Against Rheumatism systemic vasculitis task force. Ann Rheum Dis 67: 1004-1010.
51. Nesher, G., Berkun, Y., Mates, M., Baras, M., Rubinow, A. and Sonnenblick, M. ( 2004) Low-dose aspirin and prevention of cranial ischemic complications in giant cell arteritis. Arthritis Rheum 50: 1332-1337.
52. Nishino, H., Rubino, F.A., de Remee, R.A., Swanson, J.W. and Parisi, J.E. ( 1993) Neurological involvement in Wegener's granulomatosis: an analysis of 324 consecutive patients at the Mayo Clinic. Ann Neurol 33: 4-9.
53. Pipitone, N. and Salvarani, C. ( 2008) Role of imaging in vasculitis and connective tissue diseases. Best Pract Res Clin Rheumatol 22: 1075-1091.
54. Pomper, M.G., Miller, T.J., Stone, J.H., Tidmore, W.C. and Hellmann, D.B. ( 1999) CNS vasculitis in autoimmune disease: MR imaging findings and correlation with angiography. Am J Neuroradiol 20: 75-85.
55. Reinhold-Keller, E., Herlyn, K., Wagner-Bastmeyer, R., Gutfleisch, J., Peter, H.H., Raspe, H.H. et al. (2002) No difference in the incidences of vasculitides between north and south Germany: first results of the German vasculitis register. Rheumatology 41: 540-549.
56. Sable-Fourtassou, R., Cohen, P., Mahr, A., Pagnoux, C., Mouthon, L., Jayne, D. et al. (2005) Antineutrophil cytoplasmic antibodies and the Churg-Strauss syndrome. Ann Intern Med 143: 632-638.
57. Salvarani, C., Brown Jr, R.D., Calamia, K.T., Christianson, T.J.H., Huston, J., Meschia, J.F. et al. (2007) Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol 62: 442-451.
58. Salvarani, C., Brown Jr, R.D., Calamia, K.T., Christianson, T.J.H., Huston, J., Meschia, J.F. et al. (2008) Primary CNS vasculitis with spinal cord involvement. Neurology 70: 2394-2400.
59. Salvarani, C., Della Bella, C., Cimino, L., Macchioni, P., Formisano, D., Bajocchi, G. et al. (2009) Risk factors for severe cranial ischaemic events in an Italian population-based cohort of patients with giant cell arteritis. Rheumatology 48: 250-253.
60. Salvarani, C., Giannini, C., Miller, D.V. and Hunder, G. ( 2006) Giant cell arteritis: Involvement of intracranial arteries. Arthritis Rheum 55: 985-989.
61. Sanna, G., Piga, M., Terryberry, J.W., Peltz, M.T., Giagheddu, S., Satta, L. et al. (2000) Central nervous system involvement in systemic lupus erythematosus: cerebral imaging and serological profile in patients with and without overt neuropsychiatric manifestations. Lupus 9: 573-583.
62. Schmidley, J.W.( 2000) Central Nervous System Angiitis, Butterworth-Heinemann : Boston.
63. Sehgal, M., Swanson, J.W., de Remee, R.A. and Colby, T.V. ( 1995) Neurologic manifestations of Churg-Strauss syndrome. Mayo Clin Proc 70: 337-341.
64. Selga, D., Mohammad, A., Sturfelt, G. and Segelmark, M. ( 2006) Polyarteritis nodosa when applying the Chapel Hill nomenclature - a descriptive study on ten patients. Rheumatology 45: 1276-1281.
65. Sfikakis, P.P., Markomichelakis, N., Alpsoy, E., Assaad-Khalil, S., Bodaghi, B., Gul, A. et al. (2007) Anti-TNF therapy in the management of Behçet's disease-review and basis for recommendations. Rheumatology 46: 736-741.
66. Staunton, H., Stafford, F., Leader, M. and O'Riordain, D. ( 2000) Deterioration of giant cell arteritis with corticosteroid therapy. Arch Neurol 57: 581-584.
67. Stegeman, C.A., Cohen Tervaert, J.W., de Jong, P.E. and Kallenberg, C.G. ( 1996) Trimethoprimsulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis. N Engl J Med 335: 16-20.
68. Tabarki, B., Mahdhaoui, A., Selmi, H., Yacoub, M. and Essoussi, A.S. ( 2001) Kawasaki disease with predominant central nervous system involvement. Pediatr Neurol 25: 239-241.
69. Watts, R., Lane, S., Hanslik, T., Hauser, T., Hellmich, B., Koldingsnes, W. et al. (2007) Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies. Ann Rheum Dis 66: 222-227.
70. Weyand, C.M. and Goronzy, J.J. ( 1999) Arterial wall injury in giant cell arteritis. Arthritis Rheum 42: 844-853.
71. Yamada, I., Nakagawa, T., Himeno, Y., Kobayashi, Y., Numano, F. and Shibuya, H. ( 2000) Takayasu arteritis: diagnosis with breath-hold contrast-enhanced three-dimensional MR angiography. J Magn Reson Imaging 11: 481-487.
72. Yazici, H., Pazarli, H. and Barnes, C.G. ( 1990) A controlled trial of azathioprine in Behcet's syndrome. N Engl J Med 322: 281-285.