메뉴 건너뛰기




Volumn 35, Issue 4, 2010, Pages 559-563

Changes in extracellular kynurenic acid concentrations in rat prefrontal cortex after D-kynurenine infusion: An in vivo microdialysis study

Author keywords

Brain microdialysis; Column switching high performance liquid chromatography; D amino acid oxidase; D kynurenine; Kynurenic acid

Indexed keywords

3 METHYLPYRAZOLE 5 CARBOXYLIC ACID; AMINO ACID OXIDASE; BUNGAROTOXIN RECEPTOR; ENZYME INHIBITOR; KYNURENIC ACID; KYNURENINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG;

EID: 77953316471     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-0099-1     Document Type: Article
Times cited : (21)

References (41)
  • 1
    • 65549130117 scopus 로고
    • Tryptophane metabolism. X. The effect of feeding l(-)-, dl-, and d(+)-tryptophane, d(-)-and dl-β-3-indolelactic acid, β-3-indolepyruvic acid, and l(-)-kynurenine upon the storage of liver glycogen and the urinary output of kynurenic acid, kynurenine, and total acetone bodies
    • Borchers R, Berg CP, Whitman NE (1942) Tryptophane metabolism. X. The effect of feeding l(-)-, dl-, and d(+)-tryptophane, d(-)-and dl-β-3-indolelactic acid, β-3-indolepyruvic acid, and l(-)-kynurenine upon the storage of liver glycogen and the urinary output of kynurenic acid, kynurenine, and total acetone bodies. J Biol Chem 145:657-666
    • (1942) J Biol Chem , vol.145 , pp. 657-666
    • Borchers, R.1    Berg, C.P.2    Whitman, N.E.3
  • 2
    • 0015077064 scopus 로고
    • Quantitative aspects of tryptophan metabolism in humans and other species: A review
    • Leklem JE (1971) Quantitative aspects of tryptophan metabolism in humans and other species: a review. Amer J Clin Nutr 24:659-672
    • (1971) Amer J Clin Nutr , vol.24 , pp. 659-672
    • Leklem, J.E.1
  • 3
    • 1042277927 scopus 로고
    • The metabolism of D-and L-tryptophan and D-and L-kynurenine by liver and kidney preparations
    • Mason M, Berg CP (1952) The metabolism of D-and L-tryptophan and D-and L-kynurenine by liver and kidney preparations. J Biol Chem 195:515-524
    • (1952) J Biol Chem , vol.195 , pp. 515-524
    • Mason, M.1    Berg, C.P.2
  • 4
    • 33845586903 scopus 로고
    • Metabolism of D-tryptophan in the normal human subject
    • Langner RR, Berg CP (1955) Metabolism of D-tryptophan in the normal human subject. J Biol Chem 214:699-707
    • (1955) J Biol Chem , vol.214 , pp. 699-707
    • Langner, R.R.1    Berg, C.P.2
  • 5
    • 0014089302 scopus 로고
    • Enzymic formation of D-kynurenine from D-tryptophan
    • Higuchi K, Hayaishi O (1967) Enzymic formation of D-kynurenine from D-tryptophan. Arch Biochem Biophys 120:397-403
    • (1967) Arch Biochem Biophys , vol.120 , pp. 397-403
    • Higuchi, K.1    Hayaishi, O.2
  • 6
    • 0015046249 scopus 로고
    • Production of D-kynurenine and other metabolites from D-tryptophan by the intact rabbit and by rabbit tissue
    • Loh HH, Berg CP (1971) Production of D-kynurenine and other metabolites from D-tryptophan by the intact rabbit and by rabbit tissue. J Nutr 101:465-475
    • (1971) J Nutr , vol.101 , pp. 465-475
    • Loh, H.H.1    Berg, C.P.2
  • 7
    • 0033056044 scopus 로고    scopus 로고
    • Tryptophan metabolism and brain function: Focus on kynurenine and other indole metabolites
    • Moroni F (1999) Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites. Eur J Pharmacol 375:87-100
    • (1999) Eur J Pharmacol , vol.375 , pp. 87-100
    • Moroni, F.1
  • 8
    • 22144432194 scopus 로고    scopus 로고
    • Role of kynurenines in the central and peripheral nervous systems
    • Nemeth H, Toldi J, Vecsei L (2005) Role of kynurenines in the central and peripheral nervous systems. Curr Neurovascul Res 2:249-260
    • (2005) Curr Neurovascul Res , vol.2 , pp. 249-260
    • Nemeth, H.1    Toldi, J.2    Vecsei, L.3
  • 9
    • 33748288040 scopus 로고    scopus 로고
    • Tryptophan metabolism in the central nervous system: Medical implications
    • Ruddick JP, Evans AK, Nutt DJ et al (2006) Tryptophan metabolism in the central nervous system: medical implications. Expert Rev Mol Med 8:1-27
    • (2006) Expert Rev Mol Med , vol.8 , pp. 1-27
    • Ruddick, J.P.1    Evans, A.K.2    Nutt, D.J.3
  • 10
    • 23844439286 scopus 로고    scopus 로고
    • α7 Nicotinic receptor agonists as potential therapeutic drugs for schizophrenia
    • Hashimoto K, Koike K, Shimizu E et al (2005) α7 Nicotinic receptor agonists as potential therapeutic drugs for schizophrenia. Curr Med Chem Cent Nerv Syst Ag 5:171-184
    • (2005) Curr Med Chem Cent Nerv Syst Ag , vol.5 , pp. 171-184
    • Hashimoto, K.1    Koike, K.2    Shimizu, E.3
  • 11
    • 0025482465 scopus 로고
    • Cerebral synthesis and release of kynurenic acid: An endogenous antagonist of excitatory amino acid receptors
    • Swartz KJ, During MJ, Freese A et al (1990) Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors. J Neurosci 10:2965-2973
    • (1990) J Neurosci , vol.10 , pp. 2965-2973
    • Swartz, K.J.1    During, M.J.2    Freese, A.3
  • 12
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits a7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: Physiopathological implications
    • Hilmas C, Pereira EFR, Alkondon M et al (2001) The brain metabolite kynurenic acid inhibits a7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: physiopathological implications. J Neurosci 21:7463-7473
    • (2001) J Neurosci , vol.21 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.R.2    Alkondon, M.3
  • 13
    • 0035477818 scopus 로고    scopus 로고
    • Increased cortical kynurenate content in schizophrenia
    • Schwarcz R, Rassoulpour A, Wu HQ et al (2001) Increased cortical kynurenate content in schizophrenia. Biol Psychiatr 50:521-530
    • (2001) Biol Psychiatr , vol.50 , pp. 521-530
    • Schwarcz, R.1    Rassoulpour, A.2    Wu, H.Q.3
  • 14
    • 0035798252 scopus 로고    scopus 로고
    • Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia
    • Erhardt S, Blennow K, Nordin C et al (2001) Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neurosci Lett 313:96-98
    • (2001) Neurosci Lett , vol.313 , pp. 96-98
    • Erhardt, S.1    Blennow, K.2    Nordin, C.3
  • 15
    • 28244440276 scopus 로고    scopus 로고
    • Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia
    • Nilsson LK, Linderholm KR, Engberg G et al (2005) Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia. Schizophr Res 80:315-322
    • (2005) Schizophr Res , vol.80 , pp. 315-322
    • Nilsson, L.K.1    Linderholm, K.R.2    Engberg, G.3
  • 16
    • 34548494387 scopus 로고    scopus 로고
    • The kynurenic acid hypothesis of schizophrenia
    • Erhardt S, Schwieler L, Nilsson L et al (2007) The kynurenic acid hypothesis of schizophrenia. Physiol Behav 92:203-209
    • (2007) Physiol Behav , vol.92 , pp. 203-209
    • Erhardt, S.1    Schwieler, L.2    Nilsson, L.3
  • 17
    • 0025771636 scopus 로고
    • Measurement of rat brain kynurenine aminotransferase at physiological kynurenine concentrations
    • Okuno E, Schmidt W, Parks DA et al (1991) Measurement of rat brain kynurenine aminotransferase at physiological kynurenine concentrations. J Neurochem 57:533-540
    • (1991) J Neurochem , vol.57 , pp. 533-540
    • Okuno, E.1    Schmidt, W.2    Parks, D.A.3
  • 18
    • 0030696296 scopus 로고    scopus 로고
    • Characterization of rat brain kynurenine aminotransferases I and II
    • Guidetti P, Okuno E, Schwarcz R (1997) Characterization of rat brain kynurenine aminotransferases I and II. J Neurosci Res 50:457-465
    • (1997) J Neurosci Res , vol.50 , pp. 457-465
    • Guidetti, P.1    Okuno, E.2    Schwarcz, R.3
  • 19
    • 9644287902 scopus 로고    scopus 로고
    • Crystal structure of human kynurenine aminotransferase I
    • DOI 10.1074/jbc.M409291200
    • Rossi F, Han Q, Li J et al (2004) Crystal structure of human kynurenine aminotransferase I. J Biol Chem 279:50214-50220 (Pubitemid 39577835)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.48 , pp. 50214-50220
    • Rossi, F.1    Han, Q.2    Li, J.3    Li, J.4    Rizzi, M.5
  • 20
    • 41249085863 scopus 로고    scopus 로고
    • Crystal structure of human kynurenine aminotransferase II
    • Han Q, Robinson H, Li J (2008) Crystal structure of human kynurenine aminotransferase II. J Biol Chem 283:3567-3573
    • (2008) J Biol Chem , vol.283 , pp. 3567-3573
    • Han, Q.1    Robinson, H.2    Li, J.3
  • 21
    • 41249087474 scopus 로고    scopus 로고
    • Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia
    • Rossi F, Garavaglia S, Montalbano V et al (2007) Crystal structure of human kynurenine aminotransferase II, a drug target for the treatment of schizophrenia. J Biol Chem 283:3559-3566
    • (2007) J Biol Chem , vol.283 , pp. 3559-3566
    • Rossi, F.1    Garavaglia, S.2    Montalbano, V.3
  • 22
    • 62649121884 scopus 로고    scopus 로고
    • On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo
    • Amori L, Guidetti P, Pellicciari R et al (2009) On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. J Neurochem 109:316-325
    • (2009) J Neurochem , vol.109 , pp. 316-325
    • Amori, L.1    Guidetti, P.2    Pellicciari, R.3
  • 23
    • 34250156019 scopus 로고    scopus 로고
    • Mitochondrial aspartate aminotransferase: A third kynurenate-producing enzyme in the mammalian brain
    • Guidetti P, Amori L, Sapko MT et al (2007) Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain. J Neurochem 102:103-111
    • (2007) J Neurochem , vol.102 , pp. 103-111
    • Guidetti, P.1    Amori, L.2    Sapko, M.T.3
  • 24
    • 65549116075 scopus 로고    scopus 로고
    • Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: A comparative study between enantiomers
    • Fukushima T, Sone Y, Mitsuhashi S et al (2009) Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: a comparative study between enantiomers. Chirality 21:468-472
    • (2009) Chirality , vol.21 , pp. 468-472
    • Fukushima, T.1    Sone, Y.2    Mitsuhashi, S.3
  • 25
    • 0033679728 scopus 로고    scopus 로고
    • D-Amino acid oxidase: New findings
    • Pilone MS (2000) D-Amino acid oxidase: new findings. Cell Mol Life Sci 57:1732-1747
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1732-1747
    • Pilone, M.S.1
  • 26
    • 34648828681 scopus 로고    scopus 로고
    • D-Amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia
    • Corvin A, Donohoe G, McGhee K et al (2007) D-Amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia. Neurosci Lett 426:97-100
    • (2007) Neurosci Lett , vol.426 , pp. 97-100
    • Corvin, A.1    Donohoe, G.2    McGhee, K.3
  • 27
    • 70349241521 scopus 로고    scopus 로고
    • Potential pathophysiological role of D-amino acid oxidase in schizophrenia: Immunohistochemical and in situ hybridization study of the expression in human and rat brain
    • Ono K, Shishido Y, Park HK et al (2009) Potential pathophysiological role of D-amino acid oxidase in schizophrenia: immunohistochemical and in situ hybridization study of the expression in human and rat brain. J Neural Transm 116:1335-1347
    • (2009) J Neural Transm , vol.116 , pp. 1335-1347
    • Ono, K.1    Shishido, Y.2    Park, H.K.3
  • 28
    • 70349776074 scopus 로고    scopus 로고
    • Commentary: Genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: Progress and challenges
    • Williams M (2009) Commentary: genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: progress and challenges. Biochem Pharmacol 78:1360-1365
    • (2009) Biochem Pharmacol , vol.78 , pp. 1360-1365
    • Williams, M.1
  • 29
    • 38149040091 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological profile of AS057278, a selective D-amino acid oxidase inhibitor with potential anti-psychotic properties
    • Adage T, Trillat AC, Quattropani A et al (2008) In vitro and in vivo pharmacological profile of AS057278, a selective D-amino acid oxidase inhibitor with potential anti-psychotic properties. Eur Neuropsychopharmacol 18:200-214
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 200-214
    • Adage, T.1    Trillat, A.C.2    Quattropani, A.3
  • 30
    • 11844253187 scopus 로고    scopus 로고
    • Simultaneous determination of D-and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection
    • Fukushima T, Kawai J, Imai K et al (2004) Simultaneous determination of D-and L-serine in rat brain microdialysis sample using a column-switching HPLC with fluorimetric detection. Biomed Chromatogr 18:813-819
    • (2004) Biomed Chromatogr , vol.18 , pp. 813-819
    • Fukushima, T.1    Kawai, J.2    Imai, K.3
  • 31
    • 77952771606 scopus 로고    scopus 로고
    • Determination of kynurenic acid levels in rat brain microdialysis samples and changes in kynurenic acid levels induced by N-acetylaspartic acid
    • doi: 10.1002/bmc.1336
    • Tomiya M, Fukushima T, Ogaya T et al (2009) Determination of kynurenic acid levels in rat brain microdialysis samples and changes in kynurenic acid levels induced by N-acetylaspartic acid. Biomed Chromatogr. doi: 10.1002/bmc.1336
    • (2009) Biomed Chromatogr
    • Tomiya, M.1    Fukushima, T.2    Ogaya, T.3
  • 32
    • 33644753798 scopus 로고    scopus 로고
    • Improved method for the determination of kynurenic acid in rat plasma by column-switching HPLC with post-column fluorescence detection
    • Mitsuhashi S, Fukushima T, Kawai J et al (2006) Improved method for the determination of kynurenic acid in rat plasma by column-switching HPLC with post-column fluorescence detection. Anal Chim Acta 562:36-43
    • (2006) Anal Chim Acta , vol.562 , pp. 36-43
    • Mitsuhashi, S.1    Fukushima, T.2    Kawai, J.3
  • 33
    • 33845501438 scopus 로고    scopus 로고
    • Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids
    • Fukushima T, Mitsuhashi S, Tomiya M et al (2007) Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids. Clin Chim Acta 377:174-178
    • (2007) Clin Chim Acta , vol.377 , pp. 174-178
    • Fukushima, T.1    Mitsuhashi, S.2    Tomiya, M.3
  • 34
    • 34248334640 scopus 로고    scopus 로고
    • Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection
    • Fukushima T, Mitsuhashi S, Tomiya M et al (2007) Determination of rat brain kynurenic acid by column-switching HPLC with fluorescence detection. Biomed Chromatogr 21:514-519
    • (2007) Biomed Chromatogr , vol.21 , pp. 514-519
    • Fukushima, T.1    Mitsuhashi, S.2    Tomiya, M.3
  • 35
    • 0026497479 scopus 로고
    • The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations
    • Miller JM, MacGarvey U, Beal MF (1992) The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations. Neurosci Lett 146:115-118
    • (1992) Neurosci Lett , vol.146 , pp. 115-118
    • Miller, J.M.1    MacGarvey, U.2    Beal, M.F.3
  • 36
    • 75049085333 scopus 로고    scopus 로고
    • The astrocytederived a7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex
    • doi: 10.1007/s12031-009-9235-2
    • Wu HQ, Pereira EFR, Bruno JP et al (2009) The astrocytederived a7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex. J Mol Neurosci. doi: 10.1007/s12031-009-9235-2
    • (2009) J Mol Neurosci
    • Wu, H.Q.1    Pereira, E.F.R.2    Bruno, J.P.3
  • 37
    • 33847262628 scopus 로고    scopus 로고
    • Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma
    • Mitsuhashi S, Fukushima T, Arai K et al (2007) Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma. Anal Chim Acta 587:60-66
    • (2007) Anal Chim Acta , vol.587 , pp. 60-66
    • Mitsuhashi, S.1    Fukushima, T.2    Arai, K.3
  • 38
    • 50549157208 scopus 로고
    • A new pathway of D-tryptophan metabolism: Enzymic formation of kynurenic acid via D-kynurenine
    • Tashiro M, Tsukada K, Kobayashi S et al (1961) A new pathway of D-tryptophan metabolism: enzymic formation of kynurenic acid via D-kynurenine. Biochem Biophys Res Commun 6:155-160
    • (1961) Biochem Biophys Res Commun , vol.6 , pp. 155-160
    • Tashiro, M.1    Tsukada, K.2    Kobayashi, S.3
  • 39
    • 0028988978 scopus 로고
    • D-Serine, an endogenous synaptic modulator: Localization to astrocytes and glutamate-stimulated release
    • Schell MJ, Molliver ME, Snyder SH (1995) D-Serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. Proc Natl Acad Sci USA 92:3948-3952
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3948-3952
    • Schell, M.J.1    Molliver, M.E.2    Snyder, S.H.3
  • 40
    • 34548689595 scopus 로고    scopus 로고
    • D-Amino acid oxidase and serine racemase in human brain: Normal distribution and altered expression in schizophrenia
    • Verrall L, Walker M, Rawlings N et al (2007) D-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia. Eur J Neurosci 26:1657-1669
    • (2007) Eur J Neurosci , vol.26 , pp. 1657-1669
    • Verrall, L.1    Walker, M.2    Rawlings, N.3
  • 41
    • 43049108742 scopus 로고    scopus 로고
    • Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia
    • Madeira C, Freitas ME, Vargas-Lopes C et al (2008) Increased brain D-amino acid oxidase (DAAO) activity in schizophrenia. Schizophr Res 101:76-83
    • (2008) Schizophr Res , vol.101 , pp. 76-83
    • Madeira, C.1    Freitas, M.E.2    Vargas-Lopes, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.