-
1
-
-
0030993566
-
Delivery of loperamide across the blood-brain barrier with polysorbate 80-Coated polybutylcyanoacrylate nanoparticles
-
DOI 10.1023/A:1012098005098
-
Alyautdin RN, Petrov VE, Langer K, Berthold A, Kharkevich DA, Kreuter J (1997) Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Pharm Res 14:325. (Pubitemid 27160944)
-
(1997)
Pharmaceutical Research
, vol.14
, Issue.3
, pp. 325-328
-
-
Alyautdin, R.N.1
Petrov, V.E.2
Langer, K.3
Berthold, A.4
Kharkevich, D.A.5
Kreuter, J.6
-
3
-
-
0032846316
-
Involvement of multiple transporters in the oral absorption of nucleoside analogues
-
Balimane PV, Sinko PJ (1999) Involvement of multiple transporters in the oral absorption of nucleoside analogues. Adv Drug Deliv Rev 39:183.
-
(1999)
Adv Drug Deliv Rev
, vol.39
, pp. 183
-
-
Balimane, P.V.1
Sinko, P.J.2
-
4
-
-
0002056886
-
Preparation and use of liposomes as models of biological membranes
-
Bangham AD, Hill HW, Miller NGA (1974) Preparation and use of liposomes as models of biological membranes. Methods Membr Biol 1:1.
-
(1974)
Methods Membr Biol
, vol.1
, pp. 1
-
-
Bangham, A.D.1
Hill, H.W.2
Miller, N.G.A.3
-
5
-
-
0029871091
-
The blood-brain barrier principles for targeting peptides and drugs to the central nervous system
-
Begley DJ (1996) The blood-brain barrier principles for targeting peptides and drugs to the central nervous system. J Pharm Pharmacol 48:136.
-
(1996)
J Pharm Pharmacol
, vol.48
, pp. 136
-
-
Begley, D.J.1
-
6
-
-
59849122948
-
Formulation of glycerolipidic prodrugs into pegylated liposomes for brain delivery
-
Bourgeois J, Lalanne M, Pierson LA, Marsaud V, Nicolas V, Tsapis N, Ball R, Stanimirovic D, Couvreur P, Andrieux K (2009) Formulation of glycerolipidic prodrugs into pegylated liposomes for brain delivery. J Drug Del Sci Tech 19:61.
-
(2009)
J Drug del Sci Tech
, vol.19
, pp. 61
-
-
Bourgeois, J.1
Lalanne, M.2
Pierson, L.A.3
Marsaud, V.4
Nicolas, V.5
Tsapis, N.6
Ball, R.7
Stanimirovic, D.8
Couvreur, P.9
Andrieux, K.10
-
7
-
-
0033755390
-
Near infrared with principal component analysis as a novel analytical approach for nanoparticle technology
-
Brigger I, Chaminade P, Desmaele D, Peracchia MT, d'Angelo J, Gurny R, Renoir M, Couvreur P (2000) Near infrared with principal component analysis as a novel analytical approach for nanoparticle technology. Pharm Res 17:1124.
-
(2000)
Pharm Res
, vol.17
, pp. 1124
-
-
Brigger, I.1
Chaminade, P.2
Desmaele, D.3
Peracchia, M.T.4
D'Angelo, J.5
Gurny, R.6
Renoir, M.7
Couvreur, P.8
-
8
-
-
0036896915
-
Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting
-
DOI 10.1124/jpet.102.039669
-
Brigger I, Morizet J, Aubert G, Chacun H, Terrier-Lacombe MJ, Couvreur P, Vassal G (2002) Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting. J Pharmacol Exp Ther 303:928. (Pubitemid 35424373)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.303
, Issue.3
, pp. 928-936
-
-
Brigger, I.1
Morizet, J.2
Aubert, G.3
Chacun, H.4
Terrier-Lacombe, M.-J.5
Couvreur, P.6
Vassal, G.7
-
9
-
-
0034812929
-
Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery
-
Calvo P, Gouritin B, Chacun H, Desmaele D, D'Angelo J, Noel JP, Georgin D, Fattal E, Andreux JP, Couvreur P (2001) Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharm Res 18:1157.
-
(2001)
Pharm Res
, vol.18
, pp. 1157
-
-
Calvo, P.1
Gouritin, B.2
Chacun, H.3
Desmaele, D.4
D'Angelo, J.5
Noel, J.P.6
Georgin, D.7
Fattal, E.8
Andreux, J.P.9
Couvreur, P.10
-
10
-
-
0018643931
-
Adsorption of anti-neoplastic drugs to polyalkylcyanoacrylate nanoparticles and their release in calf serum
-
Couvreur P, Kante B, Roland M, Speiser P (1979) Adsorption of anti-neoplastic drugs to polyalkylcyanoacrylate nanoparticles and their release in calf serum. J Pharm Sci 68:1521.
-
(1979)
J Pharm Sci
, vol.68
, pp. 1521
-
-
Couvreur, P.1
Kante, B.2
Roland, M.3
Speiser, P.4
-
11
-
-
21344451667
-
Colloidal carriers and blood-brain barrier (BBB) translocation: A way to deliver drugs to the brain?
-
Garcia-Garcia E, Andrieux K, Gil S, Couvreur P (2005a) Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain? Int J Pharm 298:274.
-
(2005)
Int J Pharm
, vol.298
, pp. 274
-
-
Garcia-Garcia, E.1
Andrieux, K.2
Gil, S.3
Couvreur, P.4
-
12
-
-
20744435120
-
A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles
-
Garcia-Garcia E, Gil S, Andrieux K, Desmaele D, Nicolas V, Taran F, Georgin D, Andreux JP, Roux F, Couvreur P (2005b) A relevant in vitro rat model for the evaluation of blood-brain barrier translocation of nanoparticles. Cell Mol Life Sci 62:1400.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 1400
-
-
Garcia-Garcia, E.1
Gil, S.2
Andrieux, K.3
Desmaele, D.4
Nicolas, V.5
Taran, F.6
Georgin, D.7
Andreux, J.P.8
Roux, F.9
Couvreur, P.10
-
13
-
-
21344445273
-
A methodology to study intracellular distribution of nanoparticles in brain endothelial cells
-
Garcia-Garcia E, Andrieux K, Gil S, Kim HR, Le Doan T, Desmaële D, d'Angelo J, Taran F, Georgin D, Couvreur P (2005c) A methodology to study intracellular distribution of nanoparticles in brain endothelial cells. Int J Pharm 298:310.
-
(2005)
Int J Pharm
, vol.298
, pp. 310
-
-
Garcia-Garcia, E.1
Andrieux, K.2
Gil, S.3
Kim, H.R.4
Le Doan, T.5
Desmaële, D.6
D'Angelo, J.7
Taran, F.8
Georgin, D.9
Couvreur, P.10
-
14
-
-
33846809312
-
Encapsulation of dexamethasone into biodegradable polymeric nanoparticles
-
Gòmez-Gaete C, Tsapis N, Besnard M, Bochot A, Fattal E (2007) Encapsulation of dexamethasone into biodegradable polymeric nanoparticles. Int J Pharm 331:153.
-
(2007)
Int J Pharm
, vol.331
, pp. 153
-
-
Gòmez-Gaete, C.1
Tsapis, N.2
Besnard, M.3
Bochot, A.4
Fattal, E.5
-
15
-
-
13844299532
-
In vitro models for the blood-brain barrier
-
Garberg P, Ball M, Borg N, Cecchelli R, Fenart L, Hurst RD, Lindmark T, Mabondzo A, Nilsson JE, Raub TJ, Stanimirovic D, Terasaki T, Oberg JO, Osterberg T (2005) In vitro models for the blood-brain barrier. Toxicol In Vitro 19:299.
-
(2005)
Toxicol in Vitro
, vol.19
, pp. 299
-
-
Garberg, P.1
Ball, M.2
Borg, N.3
Cecchelli, R.4
Fenart, L.5
Hurst, R.D.6
Lindmark, T.7
Mabondzo, A.8
Nilsson, J.E.9
Raub, T.J.10
Stanimirovic, D.11
Terasaki, T.12
Oberg, J.O.13
Osterberg, T.14
-
16
-
-
0032712180
-
Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles
-
Gulyaev AE, Gelperina SE, Skidan IN, Antropov AS, Kivman GY, Kreuter J (1999) Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles. Pharm Res 16:1564.
-
(1999)
Pharm Res
, vol.16
, pp. 1564
-
-
Gulyaev, A.E.1
Gelperina, S.E.2
Skidan, I.N.3
Antropov, A.S.4
Kivman, G.Y.5
Kreuter, J.6
-
17
-
-
34447525116
-
Analysis of plasma protein adsorption onto PEGylated nanoparticles by complementary methods: Two-dimensional electrophoresis, capillary electrophoresis and Protein Labchip system
-
Kim HR, Andrieux K, Delomenie C, Chacun H, Appel M, Desmaële D, Taran F, Georgin D, Couvreur P, Taverna M (2007a) Analysis of plasma protein adsorption onto PEGylated nanoparticles by complementary methods: Two-dimensional electrophoresis, capillary electrophoresis and Protein Labchip system. Electrophoresis 28:2252.
-
(2007)
Electrophoresis
, vol.28
, pp. 2252
-
-
Kim, H.R.1
Andrieux, K.2
Delomenie, C.3
Chacun, H.4
Appel, M.5
Desmaële, D.6
Taran, F.7
Georgin, D.8
Couvreur, P.9
Taverna, M.10
-
18
-
-
33846985303
-
Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells
-
Kim HR, Gil S, Andrieux K, Nicolas V, Appel M, Chacun H, Desmaële D, Taran F, Georgin D, Couvreur P (2007b) Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells. Cell Mol Life Sci 64:356.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 356
-
-
Kim, H.R.1
Gil, S.2
Andrieux, K.3
Nicolas, V.4
Appel, M.5
Chacun, H.6
Desmaële, D.7
Taran, F.8
Georgin, D.9
Couvreur, P.10
-
19
-
-
33947630376
-
Translocation of poly(ethylene glycol-co-hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells: Role of apolipoproteins on receptor-mediated endocytosis
-
Kim HR, Andrieux K, Gil S, Taverna M, Chacun H, Desmaële D, Taran F, Georgin D, Couvreur P (2007c) Translocation of poly(ethylene glycol-co-hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells: role of apolipoproteins on receptor-mediated endocytosis. Biomacromolecules 12:793.
-
(2007)
Biomacromolecules
, vol.12
, pp. 793
-
-
Kim, H.R.1
Andrieux, K.2
Gil, S.3
Taverna, M.4
Chacun, H.5
Desmaële, D.6
Taran, F.7
Georgin, D.8
Couvreur, P.9
-
20
-
-
0028911362
-
Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)
-
Kreuter J, Alyautdin RN, Kharkevich DA, Ivanov AA (1995) Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles). Brain Res 674:171.
-
(1995)
Brain Res
, vol.674
, pp. 171
-
-
Kreuter, J.1
Alyautdin, R.N.2
Kharkevich, D.A.3
Ivanov, A.A.4
-
21
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
Kreuter J (2001) Nanoparticulate systems for brain delivery of drugs. Adv Drug Deliv Rev 47:65.
-
(2001)
Adv Drug Deliv Rev
, vol.47
, pp. 65
-
-
Kreuter, J.1
-
22
-
-
33947715791
-
Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV
-
Lalanne M, Paci A, Andrieux K, Dereuddre-Bosquet N, Clayette P, Deroussent A, Re M, Vassal G, Couvreur P, Desmaële D (2007a) Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV. Bioorg Med Chem Lett 17: 2237.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 2237
-
-
Lalanne, M.1
Paci, A.2
Andrieux, K.3
Dereuddre-Bosquet, N.4
Clayette, P.5
Deroussent, A.6
Re, M.7
Vassal, G.8
Couvreur, P.9
Desmaële, D.10
-
23
-
-
34648825413
-
Liposomal formulation of a glycerolipidic prodrug for lymphatic delivery of didanosine via oral route
-
Lalanne M, Andrieux K, Paci A, Besnard M, Re M, Bourgaux C, Ollivon M, Desmaële D, Couvreur P (2007b) Liposomal formulation of a glycerolipidic prodrug for lymphatic delivery of didanosine via oral route. Int J Pharm 344:62.
-
(2007)
Int J Pharm
, vol.344
, pp. 62
-
-
Lalanne, M.1
Andrieux, K.2
Paci, A.3
Besnard, M.4
Re, M.5
Bourgaux, C.6
Ollivon, M.7
Desmaële, D.8
Couvreur, P.9
-
24
-
-
0033796167
-
Rationale and applications of lipids as prodrug carriers
-
Lambert DM (2000) Rationale and applications of lipids as prodrug carriers. Eur J Pharm Sci 11:S15.
-
(2000)
Eur J Pharm Sci
, vol.11
-
-
Lambert, D.M.1
-
25
-
-
0036216605
-
HIV-1 and the brain: Connections between HIV-1-associated dementia, neuropathology and neuroimmunology
-
Lawrence DM, Major EO (2002) HIV-1 and the brain: connections between HIV-1-associated dementia, neuropathology and neuroimmunology. Microbes Infect 4:301.
-
(2002)
Microbes Infect
, vol.4
, pp. 301
-
-
Lawrence, D.M.1
Major, E.O.2
-
26
-
-
0021356699
-
Degradation of poly(isobutyl cyanoacrylate) nanoparticles
-
Lenaerts V, Couvreur P, Christiaens-Leyh D, Joiris E, Roland M, Rollman B, Speiser P (1984) Degradation of poly(isobutyl cyanoacrylate) nanoparticles. Biomaterials 5:65.
-
(1984)
Biomaterials
, vol.5
, pp. 65
-
-
Lenaerts, V.1
Couvreur, P.2
Christiaens-Leyh, D.3
Joiris, E.4
Roland, M.5
Rollman, B.6
Speiser, P.7
-
27
-
-
0030726926
-
Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood-brain barrier
-
Muruganandam A, Herx LM, Monette R, Durkin JP, Stanimirovic DB (1997) Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood-brain barrier. Faseb J 11:1187.
-
(1997)
Faseb J
, vol.11
, pp. 1187
-
-
Muruganandam, A.1
Herx, L.M.2
Monette, R.3
Durkin, J.P.4
Stanimirovic, D.B.5
-
29
-
-
57349101927
-
Synthesis of highly functionalized poly(alkyl cyanoacrylate) nanoparticles by means of click chemistry
-
Nicolas J, Bensaid F, Desmaële D, Grogna M, Detrembleur C, Andrieux K, Couvreur P (2008b) Synthesis of highly functionalized poly(alkyl cyanoacrylate) nanoparticles by means of click chemistry. Macromolecules 41:8418.
-
(2008)
Macromolecules
, vol.41
, pp. 8418
-
-
Nicolas, J.1
Bensaid, F.2
Desmaële, D.3
Grogna, M.4
Detrembleur, C.5
Andrieux, K.6
Couvreur, P.7
-
30
-
-
0032588348
-
Stealth PEGylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting
-
Peracchia MT, Fattal E, Desmaele D, Besnard M, Noel JP, Gomis JM, Appel M, d'Angelo J, Couvreur P (1999a) Stealth PEGylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting. J Contr Rel 60:121.
-
(1999)
J Contr Rel
, vol.60
, pp. 121
-
-
Peracchia, M.T.1
Fattal, E.2
Desmaele, D.3
Besnard, M.4
Noel, J.P.5
Gomis, J.M.6
Appel, M.7
D'Angelo, J.8
Couvreur, P.9
-
31
-
-
0033168385
-
Visualization of in vitro protein-rejecting properties of PEGylated stealth polycyanoacrylate nanoparticles
-
Peracchia MT, Harnisch S, Pinto-Alphandary H, Gulik A, Dedieu JC, Desmaele D, d'Angelo J, Muller RH, Couvreur P (1999b) Visualization of in vitro protein-rejecting properties of PEGylated stealth polycyanoacrylate nanoparticles. Biomaterials 20:1269.
-
(1999)
Biomaterials
, vol.20
, pp. 1269
-
-
Peracchia, M.T.1
Harnisch, S.2
Pinto-Alphandary, H.3
Gulik, A.4
Dedieu, J.C.5
Desmaele, D.6
D'Angelo, J.7
Muller, R.H.8
Couvreur, P.9
-
32
-
-
0036001389
-
Transfer of Lipophilic Markers from PLGA and Polystyrene Nanoparticles to Caco-2 Monolayers Mimics Particle Uptake
-
Pietzonka P, Rothen-Rutishauser B, Langguth P, Wunderli-Allenspach H, Walter E, Merkle HP (2002) Transfer of Lipophilic Markers from PLGA and Polystyrene Nanoparticles to Caco-2 Monolayers Mimics Particle Uptake. Pharm Res 19:595.
-
(2002)
Pharm Res
, vol.19
, pp. 595
-
-
Pietzonka, P.1
Rothen-Rutishauser, B.2
Langguth, P.3
Wunderli-Allenspach, H.4
Walter, E.5
Merkle, H.P.6
-
33
-
-
0029877991
-
N-docosahexaenoyl, 3 hydroxytyramine: A dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite
-
Shashoua VE, Hesse GW (1996) N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite. Life Sci 58:1347.
-
(1996)
Life Sci
, vol.58
, pp. 1347
-
-
Shashoua, V.E.1
Hesse, G.W.2
-
34
-
-
34648825412
-
Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules
-
Stella B, Arpicco S, Rocco F, Marsaud V, Renoir JM, Cattel L, Couvreur P (2007) Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules. Int J Pharm 344:71.
-
(2007)
Int J Pharm
, vol.344
, pp. 71
-
-
Stella, B.1
Arpicco, S.2
Rocco, F.3
Marsaud, V.4
Renoir, J.M.5
Cattel, L.6
Couvreur, P.7
-
35
-
-
0032821288
-
Concepts for the design of anti-HIV nucleoside prodrugs for treating cephalic HIV infection
-
Wiebe LI, Knaus EE (1999) Concepts for the design of anti-HIV nucleoside prodrugs for treating cephalic HIV infection. Adv Drug Deliv Rev 39:63.
-
(1999)
Adv Drug Deliv Rev
, vol.39
, pp. 63
-
-
Wiebe, L.I.1
Knaus, E.E.2
-
36
-
-
0032820953
-
Improved uptake and retention of lipophilic prodrug to improve treatment of HIV
-
Yatvin MB, Li W, Meredith MJ, Shenoy MA (1999) Improved uptake and retention of lipophilic prodrug to improve treatment of HIV. Adv Drug Deliv Rev 39:165.
-
(1999)
Adv Drug Deliv Rev
, vol.39
, pp. 165
-
-
Yatvin, M.B.1
Li, W.2
Meredith, M.J.3
Shenoy, M.A.4
|