Proteomic profiling of naturally protected extraocular muscles from the dystrophin-deficient mdx mouse

Biochemical and Biophysical Research Communications

Volumn 396, Issue 4, 2010, Pages 1024-1029

  Lewis, Caroline ^a   Ohlendieck, Kay ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Extraocular muscle; Heat shock protein; MDX; Muscle proteomics; Muscular dystrophy; Utrophin

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; APOLIPOPROTEIN A1 BINDING PROTEIN; BETA DYSTROGLYCAN; BINDING PROTEIN; CALCIUM ION; DESMIN; DYSTROPHIN; GELSOLIN; GEPHYRIN; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN; PERILIPIN 3; TRANSALDOLASE; UNCLASSIFIED DRUG; UTROPHIN;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EXTRAOCULAR MUSCLE; MALE; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; UPREGULATION; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; DYSTROPHIN; MICE; MICE, INBRED MDX; MOLECULAR SEQUENCE DATA; MUSCULAR DYSTROPHY, DUCHENNE; OCULOMOTOR MUSCLES; PROTEINS; PROTEOMICS;

EID: 77953292369     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.05.052     Document Type: Article

References (31)

1. Ahn A.H., and Kunkel L.M. The structural and functional diversity of dystrophin. Nat. Genet. 3 (1993) 283-291
2. Lewis C., Carberry S., and Ohlendieck K. Proteomic profiling of x-linked muscular dystrophy. J. Muscle Res. Cell Motil. 30 (2009) 267-269
3. O'Brien K.F., and Kunkel L.M. Dystrophin and muscular dystrophy: past, present, and future. Mol. Genet. Metab. 74 (2001) 75-88
4. Cohn C.D., and Campbell K.P. Molecular basis of muscular dystrophies. Muscle Nerve 23 (2000) 1456-1471
5. Dowling P., Culligan K., and Ohlendieck K. Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy. Naturwissenschaften 89 (2002) 75-78
6. Porter J.D., Merriam A.P., Khanna S., Andrade F.H., Richmonds C.R., Leahy P., Cheng G., Karathanasis P., Zhou X., Kusner L.L., Adams M.E., Willem M., Mayer U., and Kaminski H.J. Constitutive properties, not molecular adaptations, mediate extraocular muscle sparing in dystrophic mdx mice. FASEB J. 17 (2003) 893-895
7. Dowling P., Lohan J., and Ohlendieck K. Comparative analysis of Dp427-deficient mdx tissues shows that the milder dystrophic phenotype of extraocular and toe muscle fibres is associated with a persistent expression of beta-dystroglycan. Eur. J. Cell Biol. 82 (2003) 222-230
8. Porter J.D., Merriam A.P., Leahy P., Gong B., and Khanna S. Dissection of temporal gene expression signatures of affected and spared muscle groups in dystrophin-deficient (mdx) mice. Hum. Mol. Genet. 12 (2003) 1813-1821
9. Smythe G.M. Dystrophic pathology in the intrinsic and extrinsic laryngeal muscles in the mdx mouse. J. Otolaryngol. Head Neck Surg. 38 (2009) 323-336
10. Marques M.J., Pertille A., Carvalho C.L., and Neto H.S. Acetylcholine receptor organization at the dystrophic extraocular muscle neuromuscular junction. Anat. Rec. 290 (2007) 846-854
11. Marques M.J., Ferretti R., Vomero V.U., Minatel E., and Neto H.S. Intrinsic laryngeal muscles are spared from myonecrosis in the mdx mouse model of Duchenne muscular dystrophy. Muscle Nerve 35 (2007) 349-353
12. Cleary M., Williams G.J., and Metcalfe R.A. The pattern of extra-ocular muscle involvement in ocular myasthenia. Strabismus 16 (2008) 11-18
13. Stahl J.S., Averbuch-Heller L., Remler B.F., and Leigh R.J. Clinical evidence of extraocular muscle fiber-type specificity of botulinum toxin. Neurology 51 (1998) 1093-1099
14. Wakeman B., Babu D., Tarleton J., and Macdonald I.M. Extraocular muscle hypertrophy in myotonia congenita. J. AAPOS 12 (2008) 294-296
15. Khurana T.S., Prendergast R.A., Alameddine H.S., Tome F.M., Fardeau M., Arahata K., Sugita H., and Kunkel L.M. Absence of extraocular muscle pathology in Duchenne's muscular dystrophy: role for calcium homeostasis in extraocular muscle sparing. J. Exp. Med. 182 (1995) 467-475
16. Porter J.D., and Baker R.S. Muscles of a different 'color': the unusual properties of the extraocular muscles may predispose or protect them in neurogenic and myogenic disease. Neurology 46 (1996) 30-37
17. Andrade F.H., Porter J.D., and Kaminiski H.J. Eye muscle sparing by the muscular dystrophies: lessons to be learned?. Microsc. Res. Tech. 48 (2000) 192-203
18. Fischer M.D., Budak M.T., Bakay M., Gorospe J.R., Kjellgren D., Pedrosa-Domellof F., Hoffman E.P., and Khurana T.S. Definition of the unique human extraocular muscle allotype by expression profiling. Physiol. Genomics 22 (2005) 283-291
19. 2+ ATPases (SERCA-1 and -2) in human extraocular muscles. Invest. Ophthalmol. Vis. Sci. 44 (2003) 5057-5062
20. Stirn K.B., Smerdu V., and Erzen I. Histochemical and immunohistochemical profile of human and rat ocular medial rectus muscles. Graefes Arch. Clin. Exp. Ophthalmol. 247 (2009) 1505-1515
21. Rossi A.C., Mammucari C., Argentini C., Reggiani C., and Schiaffino S. Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles. J. Physiol. 588 (2010) 353-364
22. Sambasivan R., Gayraud-Morel B., Dumas G., Cimper C., Paisant S., Kelly R.G., and Tajbakhsh S. Distinct regulatory cascades govern extraocular and pharyngeal arch muscle progenitor cell fates. Dev. Cell 16 (2009) 810-821
23. Martinez-Conde S., and Macknik S.L. Fixational eye movements across vertebrates: comparative dynamics, physiology, and perception. J. Vis. 8 (2008) 28.1-28.16
24. Porter J.D. Extraocular muscle: cellular adaptations for a diverse functional repertoire. Ann. N. Y. Acad. Sci. 956 (2002) 7-16
25. Durbeej M., and Campbell K.P. Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models. Curr. Opin. Genet. Dev. 12 (2002) 349-361
26. Viswanathan S., Unlu M., and Minden J.S. Two-dimensional difference gel electrophoresis. Nat. Protoc. 1 (2006) 1351-1358
27. Doran P., Martin G., Dowling P., Jockusch H., and Ohlendieck K. Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP. Proteomics 6 (2006) 4610-4621
28. C. Lewis, H. Jockusch, K. Ohlendieck, Proteomic profiling of the dystrophin-deficient MDX heart reveals drastically altered levels of key metabolic and contractile proteins, J. Biomed. Biotechnol., in press.
29. Karp N.A., and Lilley K.S. Maximising sensitivity for detecting changes in protein expression: experimental design using minimal CyDyes. Proteomics 5 (2005) 3105-3115
30. Pertille A., de Carvalho C.L., Matsumura C.Y., Neto H.S., and Marques M.J. Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy. Int. J. Exp. Pathol. 91 (2010) 63-71
31. 2+-ATPase and calsequestrin are overexpressed in spared intrinsic laryngeal muscles of dystrophin-deficient mdx mice. Muscle Nerve 39 (2009) 609-615