Inhibitory effect of lactoferrin on hypertrophic differentiation of ATDC5 mouse chondroprogenitor cells

BioMetals

Volumn 23, Issue 3, 2010, Pages 477-484

  Takayama, Yoshiharu ^a   Mizumachi, Koko ^a  

^a NATIONAL INSTITUTE OF LIVESTOCK AND GRASSLAND SCIENCE   (Japan)

Author keywords

Aggrecan; Alkaline phosphatase; Hypertrophic differentiation; N cadherin; Smad2 3; Sox9

Indexed keywords

AGGRECAN; ALKALINE PHOSPHATASE; IRON BINDING PROTEIN; LACTOFERRIN; NERVE CELL ADHESION MOLECULE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFERRIN; BIOLOGICAL MARKER; CADHERIN; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE; SOX9 PROTEIN, MOUSE;

ANIMAL CELL; CARTILAGE CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CHONDROGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; EMBRYO; EMBRYONAL CARCINOMA; ENZYME ACTIVITY; IN VITRO STUDY; INHIBITION KINETICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STEM CELL; UPREGULATION; ANIMAL; BOVINAE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PHENOTYPE; PHOSPHORYLATION; TUMOR CELL LINE;

ANIMALS; BIOLOGICAL MARKERS; CADHERINS; CATTLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CHONDROCYTES; GENE EXPRESSION REGULATION; LACTOFERRIN; MICE; PHENOTYPE; PHOSPHORYLATION; SMAD2 PROTEIN; SMAD3 PROTEIN; SOX9 TRANSCRIPTION FACTOR; STEM CELLS;

BOVINAE;

EID: 77953286175     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10534-010-9291-7     Document Type: Conference Paper

References (32)

1. H Akiyama 2008 Control of chondrogenesis by the transcription factor Sox9 Mod Rheumatol 18 213 219 10.1007/s10165-008-0048-x 1:CAS:528: DC%2BD1cXmslyjsLk%3D 18351289
2. H Akiyama MC Chaboissie JF Martin A Schedl B de Crombrugghe 2002 The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6 Genes Dev 16 2813 2828 10.1101/gad.1017802 1:CAS:528:DC%2BD38Xos1Sisr0%3D 12414734 (Pubitemid 35253149)
3. FM Altaf TM Hering NH Kazmi JU Yoo B Johnstone 2006 Ascorbate-enhanced chondrogenesis of ATDC5 cells Eur Cell Mater 12 64 70 1:CAS:528: DC%2BD28Xht1Onsb7M 17096313
4. A Blais A Malet T Mikogami C Martin-Rouas D Tomé 2009 Oral bovine lactoferrin improves bone status of ovariectomized mice Am J Physiol Endocrinol Metab 296 E1281 E1288 10.1152/ajpendo.90938.2008 1:CAS:528:DC%2BD1MXnsVClt7k%3D 19336659
5. JH Brock 2002 The physiology of lactoferrin Biochem Cell Biol 80 1 6 10.1139/o01-212 1:CAS:528:DC%2BD38XitlCnsLo%3D 11908632 (Pubitemid 34194221)
6. K Burridge K Wennerberg 2004 Rho and Rac take center stage Cell 116 167 179 10.1016/S0092-8674(04)00003-0 1:CAS:528:DC%2BD2cXhtValsrs%3D 14744429 (Pubitemid 38167310)
7. R Cancedda P Castagnola FD Cancedda B Dozin R Quarto 2000 Developmental control of chondrogenesis and osteogenesis Int J Dev Biol 44 707 714 1:STN:280:DC%2BD3crgvV2ksg%3D%3D 11061435
8. J Cornish KE Callon D Naot KP Palmano T Banovic U Bava M Watson JM Lin PC Tong Q Chen VA Chan HE Reid N Fazzalari HM Baker EN Baker NW Haggarty AB Grey IR Reid 2004 Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo Endocrinology 145 4366 4374 10.1210/en.2003-1307 1:CAS:528:DC%2BD2cXnt1CitLc%3D 15166119 (Pubitemid 39120586)
9. T Furumatsu M Tsuda K Yoshida N Taniguchi T Ito M Hashimoto T Ito H Asahara 2005 Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment J Biol Chem 280 8343 8350 10.1074/jbc.M413913200 1:CAS:528:DC%2BD2MXhs1yhsrg%3D 15623506 (Pubitemid 40349737)
10. MB Goldring K Tsuchimochi K Ijiri 2006 The control of chondrogenesis J Cell Biochem 97 33 44 10.1002/jcb.20652 1:CAS:528:DC%2BD28XivV2lsw%3D%3D 16215986 (Pubitemid 43050970)
11. HY Guo L Jiang SA Ibrahim L Zhang H Zhang M Zhang FZ Ren 2009 Orally administered lactoferrin preserves bone mass and micro architecture in ovariectomized rats J Nutr 139 958 964 10.3945/jn.108.100586 1:CAS:528:DC%2BD1MXhtlCltr3K 19321577
12. W Huang UI Chung HM Kronenberg B de Crombrugghe 2001 The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones Proc Natl Acad Sci USA 98 160 165 10.1073/pnas.011393998 1:CAS:528:DC%2BD3MXkslKqsA%3D%3D 11120880 (Pubitemid 32095880)
13. T Ikeda H Kawaguchi S Kamekura N Ogata Y Mori K Nakamura S Ikegawa UI Chung 2005 Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation J Bone Miner Metab 23 337 340 10.1007/s00774-005- 0610-y 16133682 (Pubitemid 41223795)
14. C Kiani L Chen YJ Wu AJ Yee BB Yang 2002 Structure and function of aggrecan Cell Res 12 19 32 10.1038/sj.cr.7290106 11942407
15. V Lefebvre W Huang VR Harley PN Goodfellow B de Crombrugghe 1997 SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1 (II) collagen gene Mol Cell Biol 17 2336 2346 1:CAS:528:DyaK2sXhvFOhsLg%3D 9121483
16. D Legrand A Pierce E Elass M Carpentier C Mariller J Mazurier 2008 Lactoferrin structure and functions Adv Exp Med Biol 606 163 194 10.1007/978-0-387-74087-4-6 18183929
17. TF Li RJ O'Keefe D Chen 2005 TGF-beta signaling in chondrocytes Front Biosci 10 681 688 10.2741/1563 1:CAS:528:DC%2BD2MXis1SntL0%3D 15569609
18. TF Li M Darowish MJ Zuscik D Chen EM Schwarz RN Rosier H Drissi RJ O'Keefe 2006 Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation J Bone Miner Res 21 4 16 10.1359/JBMR.050911 16355269 (Pubitemid 43023222)
19. F Lorget J Clough M Oliveira MC Daury A Sabokbar E Offord 2002 Lactoferrin reduces in vitro osteoclast differentiation and resorbing activity Biochem Biophys Res Commun 296 261 266 10.1016/S0006-291X(02)00849-5 1:CAS:528:DC%2BD38XlvF2gsLo%3D 12163011
20. SA Oberlender RS Tuan 1994 Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis Development 120 177 187 1:CAS:528:DyaK2cXjtF2ktrc%3D 8119125
21. DK Panda D Miao V Lefebvre GN Hendy D Goltzman 2001 The transcription factor SOX9 regulates cell cycle and differentiation genes in chondrocytic CFK2 cells J Biol Chem 276 41229 41236 10.1074/jbc.M104231200 1:CAS:528: DC%2BD3MXosVKgtro%3D 11514554
22. S Provot E Schipani 2005 Molecular mechanisms of endochondral bone development Biochem Biophys Res Commun 328 658 665 10.1016/j.bbrc.2004.11.068 1:CAS:528:DC%2BD2MXhtVKhsbg%3D 15694399 (Pubitemid 40208303)
23. C Shukunami C Shigeno T Atsumi K Ishizeki F Suzuki Y Hiraki 1996 Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor J Cell Biol 133 457 468 10.1083/jcb.133.2.457 1:CAS:528:DyaK28XitlymsLg%3D 8609176 (Pubitemid 26131617)
24. SS Söderberg G Karlsson S Karlsson 2009 Complex and context dependent regulation of hematopoiesis by TGF-beta superfamily signaling Ann N Y Acad Sci 1176 55 69 10.1111/j.1749-6632.2009.04569.x 19796233
25. Y Takayama K Mizumachi 2001 Effects of lactoferrin on collagen gel contractile activity and myosin light chain phosphorylation in human fibroblasts FEBS Lett 508 111 116 10.1016/S0014-5793(01)03041-1 1:CAS:528: DC%2BD3MXot1OmtL4%3D 11707279 (Pubitemid 33055678)
26. Y Takayama K Mizumachi 2008 Effect of bovine lactoferrin on extracellular matrix calcification by human osteoblast-like cells Biosci Biotechnol Biochem 72 226 230 10.1271/bbb.70465 1:CAS:528:DC%2BD1cXhvF2ktrw%3D 18175916 (Pubitemid 351158970)
27. G Wang A Woods S Sabari L Pagnotta LA Stanton F Beier 2004 RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation J Biol Chem 279 13205 13214 10.1074/jbc.M311427200 1:CAS:528:DC%2BD2cXitl2ns78%3D 14726536 (Pubitemid 38445899)
28. A Woods G Wang F Beier 2005 RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis J Biol Chem 280 11626 11634 10.1074/jbc.M409158200 1:CAS:528:DC%2BD2MXisVyjt7s%3D 15665004 (Pubitemid 40418476)
29. A Woods G Wang F Beier 2007 Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions J Cell Physiol 213 1 8 10.1002/jcp.21110 1:CAS:528:DC%2BD2sXhtVehtLrK 17492773 (Pubitemid 47378786)
30. M Yagi N Suzuki T Takayama M Arisue T Kodama Y Yoda K Otsuka K Ito 2009 Effects of lactoferrin on the differentiation of pluripotent mesenchymal cells Cell Biol Int 33 283 289 10.1016/j.cellbi.2008.11.013 1:CAS:528: DC%2BD1MXivVWmu7s%3D 19103298
31. T Yamashiro XP Wang Z Li S Oya T Aberg T Fukunaga H Kamioka NA Speck T Takano-Yamamoto I Thesleff 2004 Possible roles of Runx1 and Sox9 in incipient intramembranous ossification J Bone Miner Res 19 1671 1677 10.1359/JBMR.040801 1:CAS:528:DC%2BD2cXovFWmtrk%3D 15355562 (Pubitemid 41094330)
32. X Yang L Chen X Xu C Li C Huang CX Deng 2001 TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage J Cell Biol 153 35 46 10.1083/jcb.153.1.35 1:CAS:528:DC%2BD3MXisVyhtLw%3D 11285272 (Pubitemid 34280192)