Nanomechanical constraints acting on the catalytic site of cellular RNA polymerases

Biochemical Society Transactions

Volumn 38, Issue 2, 2010, Pages 428-432

  Weinzierl, Robert O J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Bridge helix; Constrained catalytic site; High throughput structure function analysis; RNA polymerase; RNA polymerase IV (RNAP IV); RNA polymerase V (RNAP V); Trigger loop

Indexed keywords

NUCLEOTIDE; RNA POLYMERASE; RNA POLYMERASE IV; RNA POLYMERASE V; UNCLASSIFIED DRUG; DNA DIRECTED RNA POLYMERASE; NANOMATERIAL;

CATALYSIS; CONFORMATIONAL TRANSITION; HIGH THROUGHPUT SCREENING; METHANOCOCCUS JANNASCHII; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; RNA SEQUENCE; ROBOTICS; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; BIOMECHANICS; CELL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; METHANOCOCCUS; MOLECULAR GENETICS; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ARCHAEA; BACTERIA (MICROORGANISMS); EUKARYOTA; METHANOCALDOCOCCUS JANNASCHII;

AMINO ACID SEQUENCE; BIOMECHANICS; CATALYTIC DOMAIN; CELLS; DNA-DIRECTED RNA POLYMERASES; HUMANS; METHANOCOCCACEAE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; NANOSTRUCTURES; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77953280325     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0380428     Document Type: Review

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