Brain renin-angiotensin system modifies the blood pressure response to intracerebroventricular cadmium in rats

Drug and Chemical Toxicology

Volumn 33, Issue 3, 2010, Pages 302-309

  Varoni, Maria V ^a   Palomba, Domenico ^a   MacCiotta, Nicolò P ^a   Antuofermo, Elisabetta ^a   Deiana, Graziella ^b   Baralla, Elena ^a   Anania, Vittorio ^a   Demontis, Maria P ^a  

^a UNIVERSITY OF SASSARI   (Italy)

^b EXPERIMENTAL ZOOPROPHYLACTIC INSTITUTE OF SARDINIA   (Italy)

Author keywords

ACE inhibitors; AT receptor antagonist; Cadmium; Intracerebroventricular (ICV); Kallikrein; Kinins; RAS

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II; CADMIUM; CADMIUM ACETATE; CAPTOPRIL; CLONIDINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; KALLIKREIN; SARALASIN; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BODY WEIGHT; CONTROLLED STUDY; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HEMODYNAMICS; HISTOPATHOLOGY; HYPERTENSION; KALLIKREIN KININ SYSTEM; KALLIKREIN URINE LEVEL; KIDNEY CORTEX; KIDNEY MASS; KIDNEY SIZE; KIDNEY TUBULE BASEMENT MEMBRANE; KIDNEY TUBULE NECROSIS; MALE; NONHUMAN; RAT; RAT STRAIN; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; WISTAR RAT; ANIMAL; BLOOD; BRAIN; CHEMICALLY INDUCED; CYTOCHEMISTRY; DRUG EFFECTS; HEART; KIDNEY; PATHOPHYSIOLOGY; PHYSIOLOGY; URINE;

ADRENERGIC ALPHA-AGONISTS; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BRAIN; CADMIUM; CAPTOPRIL; CLONIDINE; ENALAPRIL; HEART; HISTOCYTOCHEMISTRY; HYPERTENSION; KALLIKREIN-KININ SYSTEM; KALLIKREINS; KIDNEY; MALE; RATS; RATS, WISTAR; RENIN-ANGIOTENSIN SYSTEM; SARALASIN;

ANIMALIA; RATTUS;

EID: 77953261282     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480540903418496     Document Type: Article

References (51)

1. Amundsen, E., Putter, J., Friberger, P., Knos, M., Larsbraten, M., Claeson, G. (1979). Methods for the determination of glandular kallikrein by means of a cromogenic tripeptide substrate. Adv Exp Med 102A:83-95.
2. Averill, D. B., Diz, D. I. (2000). Angiotensin peptides and baroreflex control of sympathetic outflow: pathways and mechanisms of the medulla oblongata. Brain Res Bull 51:119-128.
3. Buggy, J., Fisher, A. E., Hoffman, W. E., Johnson, A. L., Phillips, M. I. (1975). Ventricular obstruction: effect of drinking induced by intracranial injection of angiotensin. Science 190:72-74.
4. Bunnemann, B., Fuxe, K., Ganten, D. (1992). The brain reninangiotensin system: localization and general significance. J Cardiovasc Pharmacol 19:S51-S62.
5. Chen, L., Liu, L., Luo, Y., Huang, S. (2008). MAPK and mTOR pathways are involved in cadmium-induced neural apoptosis. J Neurochem 105:251-261.
6. de Gasparo, M., Siragy, H. M. (1999). The AT2 receptor: fact, fancy, and fantasy. Regul Pept 81:11-24.
7. Demontis, M. P., Varoni, M. V., Volpe, A. R., Emanueli, C., Madeddu, P. (1998). Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium. Br J Pharmacol 123:129-135.
8. Dzau, V. J. (1998). Cardiac renin-angiotensin: molecular and functional aspects. Am J Med 84:22-27.
9. Dzau, V. J., Akishita, M., Yamada, H. (1998). Role of the AT2 receptor in vascular development and remodelling. In: Ulfendahl, H. R., Aurell, M. (Eds.), Renin angiotensin (pp 37-45). London: Portland Press.
10. Filipic, M., Hei, T. K. (2004). Mutagenicity of cadmium in mammalian cells: implication of oxidative DNA damage. Mutat Res 546:81-91.
11. Gusev, K., Domenighetti, A. A., Delbridge, L. M., Pedrazzini, T., Niggli, E., Egger, M. (2009). Angiotensin II-mediated adaptive and maladaptive remodelling of cardiomyocyte excitationcontraction coupling. Circ Res 105:42-50.
12. Haberl, R. L. (1994). Role of angiotensin receptor subtypes in the response of rabbit brain arterioles to angiotensin. Stroke 35:1476-1480.
13. Hogarty, D. C., Speakman, E. A., Puig, V., Phillips, M. I. (1992). The role of angiotensin, AT1 and AT2 receptors in the pressor, drinking, and vasopressin responses to central angiotensin. Brain Res 586:289-294.
14. Johnson, A. K., Gross, P. M. (1993). Sensory circumventricular organs and brain homeostatic pathways. FASEB J 7:678-686.
15. Liu, X., Bellamy, C. O. C., Bailey, M. A., Mullins, L. J., Dunbar, D. R, Kenion, C. J., et al. (2009). Angiotensin-converting enzyme is a modifier of hypertensive and organ damage. J Biol Chem 284:15564-15572.
16. Madeddu, P., Demontis, M. P., Varoni, M. V., Fattaccio, M. C., Palmieri, A., Anania, V. (1993). Verapamil prevents the acute hypertensive response to intracerebroventricular cadmium in conscious normotensive rats. Am J Hypertens 6:193-197.
17. Madeddu, P., Varoni, M. V., Demontis, M. P., Pinna Parpaglia, P., Glorioso, N., Anania, V. (1996). Urinary kallikrein: a marker of blood pressure sensitivity to salt. Kidney Int 49:1422-1427.
18. Madeddu, P., Varoni, M. V., Demontis, M. P., Chao, J., Simson, J. A., Glorioso, N., et al. (1997a). Kallikrein-kinin system and blood pressure sensitivity to salt. Hypertension 29:471-477.
19. Madeddu, P., Varoni, M. V., Palomba, D., Emanueli, C., Demontis, M. P., Glorioso, N., et al. (1997b). Cardiovascular phenotype of a mouse strain with disruption of B2-receptor gene. Circulation 96:3570-3578.
20. Madeddu, P., Vio, C. P., Straino, S., Salis, M. B., Milia, A. F., Emanueli, C. (2001). Renal phenotype of low kallikrein rats. Kidney Int 59:2233-2242.
21. Majima, M., Mizogami, S., Kuribayashi, Y., Katori, M, Oh-ishi, S. (1994). Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficent rats. Hypertension 24:111-119.
22. Martynowicz, H., Skoczynska, A., Wojakowska, A., Turczyn, B. (2004). Serum vasoactive agents in rats poisoned with cadmium. Int J Occup Med Environ Health 17:479-485.
23. Mercure, C., Prescott, G., Lacombe, M. J., Silversides, D. W., Reudelhuber, T. L. (2009). Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies. Hypertension 53:1062-1069.
24. Mizuno, K., Nakamata, M., Higashimori, K. (1988). Local generation and release of angiotensin II in peripheral vascular tissue. Hypertension 11:23-29.
25. Moretti, J. L., Burke, S. L., Evans, R. G., Lambert, G. W., Head, G. A. (2009). Enhanced responses to ganglion blockade do not reflect sympathetic nervous system contribution to angiotensin II-induced hypertension. J Hypertens 27:1838-1848.
26. Mulrow, P. J. (1993). The adrenal cortical renin-angiotensin system. In:Robertson, J. I. S., Nicholls, M. G. (Eds.), The reninangiotensin system, vol 1 (pp 44.1-44.9). London: Gower Medical Publishing.
27. Muntzenmayer, D. H., Greenm A. S. (1996). Opposing action of angiotensin II on microvascular growth and blood pressure. Hypertension 27:760-765.
28. Oite, T., Yao, J. (2009). Disturbance of glomerular hemodynamics: a risk factor determining progression of glomerular diseases? J Nephrol 22:196-202.
29. Oner, G., Senturk, U. K., Izgut-Uysal, V. N. (1996). Role of cadmium-induced lipid peroxidation in the kidney response to atrial natriuretic hormone. Nephron 72:257-262.
30. Pendergrass, K. D., Gwathmey, T. M., Michalek, R. D., Graison, J. M., Chappel, M. C. (2009). The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus. Biochem Biophys Res Commun 384:149-154.
31. Pierucci-Alves, F., Schultz, B. D. (2008). Bradykinin-stimulated cyclooxygenase activity stimulates vas deferens epithelial anion secretion in vitro in swine and humans. Biol Reprod 79:501-509.
32. Pravanec, M., Cren, V., Cunes, J., Scicli, A. G., Carretero, O. A., Simonet, L., et al. (1991). Cosegregation of blood pressure with a kallikrein gene family polymorphism. Hypertension 17:242-246.
33. Puri, V. N., Tandon, V. (1997). Effect of repeated administration of cadmium, captopril, and its combination on plasma renin activity in rats. Pharmacol Res 36:411-414.
34. Puri, V. N. (1999). Cadmium-induced hypertension. Clin Exp Hypertens 21(1-2):79-84.
35. Reid, J. A. (1977). Is there a brain renin-angiotensin system? Circ Res 41:147-153.
36. Saavedra, J. M., Chevillard, C. (1982). Angiotensin-converting enzyme is present in the subfornical organ and other circumventricular organs of the rats. Neurosci Lett 29:123-127.
37. Saavedra, J. M. (1992). Brain and pituitary angiotensin. Endocr Rev 13:329-380.
38. Schinke, M., Baltatu, O., Bohm, M., Peters, J., Rascher, W., Bricca, G., et al. (1999). Blood pressure reduction and diabetes insipidus in transgenic rats deficent in brain angiotensinogen. Proc Natl Acad Sci 96:3975-3980.
39. Soares de Moura, R., Resende, A. C., Emiliano, A. F., Tano, T., Mendes-Ribeiro, A. C., Correia, M. L., et al. (2004). The role of bradykinin, AT2, and angiotensin 1-7 receptors in the EDRF-dependent vasodilator effect of angiotensin II on the isolated mesenteric vascular bed of the rat. Br J Pharmacol 141:860-866.
40. Song, Q., Chao, J., Chao, L. (1996). High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model. Clin Exp Hypertens 18:975-993.
41. Sudano, I., Noll, G. (2009). Dual blockade versus single blockade of the renin-angiotensin system in the light of ONTARGET. J Hypertens 27:S11-S14.
42. Szczepanska-Sadowska, E., Paczwa, P., Lon, S., Ganten, D. (1998). Increased pressor function of central vasopressinergic system in hypertensive renin transgenic rats. J Hypertens 16:1505-1514.
43. Tamura, K., Umemura, S., Nyui, N., Yamakawa, T., Yamaguchi, S., Ishigami, T., et al. (1996). Tissue-specific regulation of angiotensinogen gene expression in spontaneously hypertensive rats. Hypertension 27:1216-1223.
44. Teruya, H., Muratani, H., Takishita, S., Sesoko, S., Matayoshi, R., Fukiyama, K. (1995). Brain angiotensin II contributes to the development of hypertension in Dahl-Iwai salt-sensitive rats. J Hypertens 13:883-890.
45. Toda, N., Ayaziki, K., Okamura, T. (1990). Modification by endogenous prostaglandins of angiotensin II-induced contraction in dogs and monkey cerebral and mesenteric arteries. J Pharmacol Exp Ther 252:374-379.
46. Varoni, M. V., Palomba, D., Satta, M., Satta, A., Anania, V. (2003a). Different response of intracerebroventricular cadmium administration on blood pressure in normal and low urinary kallikrein rats. Pharmacol Res 47:157-162.
47. Varoni, M. V., Palomba, D., Satta, M., Anania, V. (2003b). Low urinary kallikrein rats: different sensitivity of verapamil on hypertensive response to central acute cadmium administration. Vet Human Toxicol 45:202-206.
48. Veerasingham, S. J., Raizada, M. K. (2003). Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives. Br J Pharmacol 139:191-202.
49. Waalkes, M. P. (2003). Cadmium carcinogenesis. Mutat Res 533:107-120.
50. Wang, J., Xiong, W., Yang, Z., Davis, T., Dewey, M. J., Chao, J., et al. (1994). Human tissue kallikrein induces hypotension in transgenic mice. Hypertension 23:236-243.
51. Wirth, K. J., Linz, W., Wiemer, G., Scholkens, B. A. (1997). Kinins and cardioprotection. Pharmacol Res 35:527-530.