Nerve growth factor enhances Clara cell proliferation after lung injury

European Respiratory Journal

Volumn 36, Issue 1, 2010, Pages 105-115

  Sonar, S S ^a   Schwinge, D ^a   Kilic, A ^a   Yildirim, A O ^a   Conrad, M L ^a   Seidler, K ^a   Muller B ^a   Renz, H ^a   Nockher, W A ^a  

^a UNIVERSITY HOSPITAL MARBURG   (Germany)

Author keywords

Airway epithelium; Alveolar type II cells; Clara cells; Lung injury and repair; Naphthalene; Nerve growth factor

Indexed keywords

COLLAGEN TYPE 1; FIBRONECTIN; MESSENGER RNA; NAPHTHALENE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; TROPOMYOSIN; TROPOMYOSIN RECEPTOR KINASE A; UNCLASSIFIED DRUG; NAPHTHALENE DERIVATIVE; PROTEIN KINASE; TROPOMYOSIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL RENEWAL; CLARA CELL; CONTROLLED STUDY; FEMALE; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WOUND CLOSURE; ANIMAL; BRONCHIOLE; C57BL MOUSE; CELL CULTURE; CELL MOTION; CHEMICALLY INDUCED; METABOLISM; TOXICITY; TRANSGENIC MOUSE;

ANIMALS; BRONCHIOLES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE I; FEMALE; FIBRONECTINS; LUNG INJURY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NAPHTHALENES; NERVE GROWTH FACTOR; PROTEIN KINASES; RECEPTORS, NERVE GROWTH FACTOR;

EID: 77953237212     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00165508     Document Type: Article

References (42)

1. Knight DA, Holgate ST. The airway epithelium: structural and functional properties in health and disease. Respirology 2003; 8: 432-446.
2. Mason RJ. Biology of alveolar type II cells. Respirology 2006; 11: S12-S15.
3. Lee TS, Liu YJ, Tang GJ, et al. Wood smoke extract promotes both apoptosis and proliferation in rat alveolar epithelial type II cells: the role of oxidative stress and heme oxygenase-1. Crit Care Med 2008; 36: 2597-2606.
4. Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol 2002; 161: 173-182. (Pubitemid 34760783)
5. Reynolds SD, Giangreco A, Power JH, et al. Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am J Pathol 2000; 156: 269-278. (Pubitemid 30644460)
6. Boers JE, Ambergen AW, Thunnissen FB. Number and proliferation of clara cells in normal human airway epithelium. Am J Respir Crit Care Med 1999; 159: 1585-1591.
7. Zahm JM, Chevillard M, Puchelle E. Wound repair of human surface respiratory epithelium. Am J Respir Cell Mol Biol 1991; 5: 242-248.
8. Atkinson JJ, Adair-Kirk TL, Kelley DG, et al. Clara cell adhesion and migration to extracellular matrix. Respir Res 2008; 9: 1.
9. Buckpitt AR, Castagnoli N Jr, Nelson SD, et al. Stereoselectivity of naphthalene epoxidation by mouse, rat, and hamster pulmonary, hepatic, and renal microsomal enzymes. Drug Metab Dispos 1987; 15: 491-498.
10. Plopper CG, Suverkropp C, Morin D, et al. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene. J Pharmacol Exp Ther 1992; 261: 353-363.
11. Van Winkle LS, Buckpitt AR, Nishio SJ, et al. Cellular response in naphthalene-induced Clara cell injury and bronchiolar epithelial repair in mice. Am J Physiol 1995; 269: L800-L818.
12. Takizawa H, Beckmann JD, Shoji S, et al. Pulmonary macrophages can stimulate cell growth of bovine bronchial epithelial cells. Am J Respir Cell Mol Biol 1990; 2: 245-255.
13. Lewin GR, Barde YA. Physiology of the neurotrophins. Annu Rev Neurosci 1996; 19: 289-317.
14. Freund-Michel V, Frossard N. The nerve growth factor and its receptors in airway inflammatory diseases. Pharmacol Ther 2008; 117: 52-76. (Pubitemid 350192671)
15. Raap U, Fokkens W, Bruder M, et al. Modulation of neurotrophin and neurotrophin receptor expression in nasal mucosa after nasal allergen provocation in allergic rhinitis. Allergy 2008; 63: 468-475.
16. Path G, Braun A, Meents N, et al. Augmentation of allergic early-phase reaction by nerve growth factor. Am J Respir Crit Care Med 2002; 166: 818-826.
17. Hahn C, Islamian AP, Renz H, et al. Airway epithelial cells produce neurotrophins and promote the survival of eosinophils during allergic airway inflammation. J Allergy Clin Immunol 2006; 117: 787-794.
18. Stanzel RD, Lourenssen S, Blennerhassett MG. Inflammation causes expression of NGF in epithelial cells of the rat colon. Exp Neurol 2008; 211: 203-213.
19. Marinova TS, Markova M, Aloe L. NGF overexpression and distribution in cortical thymic epithelial cells of mice with experimentally-induced leukemia. In Vivo 2006; 20: 259-264.
20. Hayashi K, Storesund T, Schreurs O, et al. Nerve growth factor β/pro-nerve growth factor and their receptors in normal human oral mucosa. Eur J Oral Sci 2007; 115: 344-354.
21. Gigliozzi A, Alpini G, Baroni GS, et al. Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis. Gastroenterology 2004; 127: 1198-1209.
22. Muangman P, Muffley LA, Anthony JP, et al. Nerve growth factor accelerates wound healing in diabetic mice. Wound Repair Regen 2004; 12: 44-52. (Pubitemid 38249135)
23. Cellini M, Bendo E, Bravetti GO, et al. The use of nerve growth factor in surgical wound healing of the cornea. Ophthalmic Res 2006; 38: 177-181. (Pubitemid 44213976)
24. Nithya M, Suguna L, Rose C. The effect of nerve growth factor on the early responses during the process of wound healing. Biochim Biophys Acta 2003; 1620: 25-31. (Pubitemid 36197893)
25. Hoyle GW, Graham RM, Finkelstein JB, et al. Hyperinnervation of the airways in transgenic mice overexpressing nerve growth factor. Am J Respir Cell Mol Biol 1998; 18: 149-157. (Pubitemid 128355188)
26. Society for Laboratory Animal Sciences. The guidelines for the care and use of experimental animals. Biberach an der Riss, GV-SOLAS, 1988.
27. Yildirim AO, Bulau P, Zakrzewicz D, et al. Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. Am J Respir Cell Mol Biol 2006; 35: 436-443. (Pubitemid 44477644)
28. Sel S, Wegmann M, Dicke T, et al. Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme. J Allergy Clin Immunol 2008; 121: 910-916.
29. Weibel ER, Hsia CC, Ochs M. How much is there really? Why stereology is essential in lung morphometry. J Appl Physiol 2007; 102: 459-467.
30. Stevens TP, McBride JT, Peake JL, et al. Cell proliferation contributes to PNEC hyperplasia after acute airway injury. Am J Physiol 1997; 272: L486-L493.
31. Nockher WA, Renz H. Neurotrophins in allergic diseases: from neuronal growth factors to intercellular signalingmolecules. J Allergy Clin Immunol 2006; 117: 583-589.
32. Lommatzsch M, Braun A, Mannsfeldt A, et al. Abundant production of brain-derived neurotrophic factor by adult visceral epithelia. Implications for paracrine and target-derived Neurotrophic functions. Am J Pathol 1999; 155: 1183-1193.
33. Frossard N, Naline E, Olgart HC, et al. Nerve growth factor is released by IL-1b and induces hyperresponsiveness of the human isolated bronchus. Eur Respir J 2005; 26: 15-20.
34. Tortorolo L, Langer A, Polidori G, et al. Neurotrophin overexpression in lower airways of infants with respiratory syncytial virus infection. Am J Respir Crit Care Med 2005; 172: 233-237. (Pubitemid 40981199)
35. Ricci A, Graziano P, Bronzetti E, et al. Increased pulmonary neurotrophin protein expression in idiopathic interstitial pneumonias. Sarcoidosis Vasc Diffuse Lung Dis 2007; 24: 13-23. (Pubitemid 350177768)
36. Matsuda H, Koyama H, Sato H, et al. Role of nerve growth factor in cutaneous wound healing: accelerating effects in normal and healing-impaired diabetic mice. J Exp Med 1998; 187: 297-306. (Pubitemid 28080059)
37. Matsuda H, Koyama H, Sato H, et al. Role of nerve growth factor in cutaneous wound healing: accelerating effects in normal and healing-impaired diabetic mice. J Exp Med 1998; 187: 297-306.
38. Lambiase A, Manni L, Bonini S, et al. Nerve growth factor promotes corneal healing: structural, biochemical, and molecular analyses of rat and human corneas. Invest Ophthalmol Vis Sci 2000; 41: 1063-1069. (Pubitemid 30187542)
39. Holgate ST, Lackie P, Wilson S, et al. Bronchial epithelium as a key regulator of airway allergen sensitization and remodeling in asthma. Am J Respir Crit Care Med 2000; 162: S113-S117.
40. Dagnell C, Kemi C, Klominek J, et al. Effects of neurotrophins on human bronchial smooth muscle cell migration and matrix metalloproteinase-9 secretion. Transl Res 2007; 150: 303-310. (Pubitemid 47628851)
41. Freund-Michel V, Bertrand C, Frossard N. TrkA signalling pathways in human airway smooth muscle cell proliferation. Cell Signal 2006; 18: 621-627.
42. Micera A, Vigneti E, Pickholtz D, et al. Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair. Proc Natl Acad Sci USA 2001; 98: 6162-6167.