메뉴 건너뛰기




Volumn 16, Issue 7, 2010, Pages 317-320

Genetic alterations in malignant melanoma

Author keywords

BRAF; CDKN2A; melanoma; mutations; PTEN; RAS

Indexed keywords

ALPHA INTERFERON; BETA CATENIN; CORTICOTROPIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DACARBAZINE; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 2; INTERMEDIN; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOPHENOL MONOOXYGENASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAS PROTEIN; TEMOZOLOMIDE; TYROSINASE RELATED PROTEIN 1; WNT PROTEIN;

EID: 77953233478     PISSN: 17562317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mpdhp.2010.03.001     Document Type: Article
Times cited : (3)

References (25)
  • 1
    • 33847220364 scopus 로고    scopus 로고
    • Melanoma biology and new targeted therapy
    • Gray-Schopfer V., Wellbrock C., and Marais R. Melanoma biology and new targeted therapy. Nature 445 (2007) 851-857
    • (2007) Nature , vol.445 , pp. 851-857
    • Gray-Schopfer, V.1    Wellbrock, C.2    Marais, R.3
  • 2
    • 34047199547 scopus 로고    scopus 로고
    • Malignant melanoma in the 21st century, part 2: staging, prognosis, and treatment
    • Markovic S.N., Erickson L.A., Rao R.D., et al. Malignant melanoma in the 21st century, part 2: staging, prognosis, and treatment. Mayo Clin Proc 82 (2007) 490-513
    • (2007) Mayo Clin Proc , vol.82 , pp. 490-513
    • Markovic, S.N.1    Erickson, L.A.2    Rao, R.D.3
  • 4
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • Tsao H., Atkins M.B., and Sober A.J. Management of cutaneous melanoma. N Engl J Med 351 (2004) 998-1012
    • (2004) N Engl J Med , vol.351 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 5
    • 74449093973 scopus 로고    scopus 로고
    • A comprehensive catalogue of somatic mutations from a human cancer genome
    • Pleasance E.D., Cheetham R.K., Stephens P.J., et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 463 (2010) 191-196
    • (2010) Nature , vol.463 , pp. 191-196
    • Pleasance, E.D.1    Cheetham, R.K.2    Stephens, P.J.3
  • 6
    • 65649147543 scopus 로고    scopus 로고
    • Braf (V600E) cooperates with Pten loss to induce metastatic melanoma
    • Dankort D., Curley D.P., Cartlidge R.A., et al. Braf (V600E) cooperates with Pten loss to induce metastatic melanoma. Nat Genet 41 (2009) 544-552
    • (2009) Nat Genet , vol.41 , pp. 544-552
    • Dankort, D.1    Curley, D.P.2    Cartlidge, R.A.3
  • 7
  • 8
    • 40849094167 scopus 로고    scopus 로고
    • Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site
    • Platz A., Egyhazi S., Ringborg U., and Hansson J. Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site. Mol Oncol 1 (2008) 395-405
    • (2008) Mol Oncol , vol.1 , pp. 395-405
    • Platz, A.1    Egyhazi, S.2    Ringborg, U.3    Hansson, J.4
  • 9
    • 0348223934 scopus 로고    scopus 로고
    • NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression
    • Omholt K., Platz A., Kanter L., Ringborg U., and Hansson J. NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression. Clin Cancer Res 9 (2003) 6483-6488
    • (2003) Clin Cancer Res , vol.9 , pp. 6483-6488
    • Omholt, K.1    Platz, A.2    Kanter, L.3    Ringborg, U.4    Hansson, J.5
  • 10
    • 41049114747 scopus 로고    scopus 로고
    • How to make a melanoma: what do we know of the primary clonal events?
    • Bennet D. How to make a melanoma: what do we know of the primary clonal events?. Pigment Cell Melanoma Res 21 (2008) 27-38
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 27-38
    • Bennet, D.1
  • 11
    • 0034491067 scopus 로고    scopus 로고
    • Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features
    • Bastian B.C., LeBoit P.E., and Pinkel D. Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features. Am J Pathol 157 (2000) 967-972
    • (2000) Am J Pathol , vol.157 , pp. 967-972
    • Bastian, B.C.1    LeBoit, P.E.2    Pinkel, D.3
  • 12
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H., Bignell G.R., Cox C., et al. Mutations of the BRAF gene in human cancer. Nature 417 (2002) 949-954
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 13
    • 23244447037 scopus 로고    scopus 로고
    • BRAFE600-associated senescence-like cell cycle arrest of human naevi
    • Michaloglou C., Vredeveld L.C., Soengas M.S., et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 436 (2005) 720-724
    • (2005) Nature , vol.436 , pp. 720-724
    • Michaloglou, C.1    Vredeveld, L.C.2    Soengas, M.S.3
  • 14
    • 70349193673 scopus 로고    scopus 로고
    • Development of a novel chemical class of BRAF inhibitors offers new hope for melanoma treatment
    • Smalley K.S., and Flaherty K.T. Development of a novel chemical class of BRAF inhibitors offers new hope for melanoma treatment. Future Oncol 5 (2009) 775-778
    • (2009) Future Oncol , vol.5 , pp. 775-778
    • Smalley, K.S.1    Flaherty, K.T.2
  • 15
    • 59449085455 scopus 로고    scopus 로고
    • Imatinib targeting of KIT-mutant oncoprotein in melanoma
    • Jiang X., Zhou J., Yuen N.K., et al. Imatinib targeting of KIT-mutant oncoprotein in melanoma. Clin Cancer Res 14 (2008) 7726-7732
    • (2008) Clin Cancer Res , vol.14 , pp. 7726-7732
    • Jiang, X.1    Zhou, J.2    Yuen, N.K.3
  • 16
    • 0032523833 scopus 로고    scopus 로고
    • Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization
    • Bastian B.C., LeBoit P.E., Hamm H., Brocker E.B., and Pinkel D. Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization. Cancer Res 58 (1998) 2170-2175
    • (1998) Cancer Res , vol.58 , pp. 2170-2175
    • Bastian, B.C.1    LeBoit, P.E.2    Hamm, H.3    Brocker, E.B.4    Pinkel, D.5
  • 18
    • 33847282821 scopus 로고    scopus 로고
    • Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents
    • Goldstein A.M., Chan M., Harland M., et al. Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents. J Med Genet 44 (2007) 99-106
    • (2007) J Med Genet , vol.44 , pp. 99-106
    • Goldstein, A.M.1    Chan, M.2    Harland, M.3
  • 19
    • 67049168909 scopus 로고    scopus 로고
    • The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
    • Yu H., McDaid R., Lee J., et al. The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes. Am J Pathol 174 (2009) 2367-2377
    • (2009) Am J Pathol , vol.174 , pp. 2367-2377
    • Yu, H.1    McDaid, R.2    Lee, J.3
  • 20
    • 33747332544 scopus 로고    scopus 로고
    • Malignant melanoma: genetics and therapeutics in the genomic era
    • Chin L., Garraway L.A., and Fisher D.E. Malignant melanoma: genetics and therapeutics in the genomic era. Genes Dev 20 (2006) 2149-2182
    • (2006) Genes Dev , vol.20 , pp. 2149-2182
    • Chin, L.1    Garraway, L.A.2    Fisher, D.E.3
  • 21
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 14 (2000) 1837-1851
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 22
    • 0034527864 scopus 로고    scopus 로고
    • Melanocyte development and malignant melanoma
    • Goding C.R. Melanocyte development and malignant melanoma. Forum (Genova) 10 (2000) 176-187
    • (2000) Forum (Genova) , vol.10 , pp. 176-187
    • Goding, C.R.1
  • 23
    • 0032937232 scopus 로고    scopus 로고
    • Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma
    • Rimm D.L., Caca K., Hu G., Harrison F.B., and Fearon E.R. Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. Am J Pathol 154 (1999) 325-329
    • (1999) Am J Pathol , vol.154 , pp. 325-329
    • Rimm, D.L.1    Caca, K.2    Hu, G.3    Harrison, F.B.4    Fearon, E.R.5
  • 24
    • 0034837773 scopus 로고    scopus 로고
    • MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations
    • Box N.F., Duffy D.L., Chen W., et al. MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations. Am J Hum Genet 69 (2001) 765-773
    • (2001) Am J Hum Genet , vol.69 , pp. 765-773
    • Box, N.F.1    Duffy, D.L.2    Chen, W.3
  • 25
    • 75549084094 scopus 로고    scopus 로고
    • Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma
    • Duffy D.L., Zhao Z.Z., Sturm R.A., Hayward N.K., Martin N.G., and Montgomery G.W. Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma. J Invest Dermatol 130 (2010) 520-528
    • (2010) J Invest Dermatol , vol.130 , pp. 520-528
    • Duffy, D.L.1    Zhao, Z.Z.2    Sturm, R.A.3    Hayward, N.K.4    Martin, N.G.5    Montgomery, G.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.