Anticholinergic effects of cis- and trans-isomers of two metabolites of propiverine

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 381, Issue 4, 2010, Pages 329-338

  Propping, Stefan ^a   Braeter, Manfred ^b   Grimm, Marc Oliver ^a   Wirth, Manfred P ^a   Ravens, Ursula ^c   Wuest, Melinda ^d  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b APOGEPHA Arzneimittel GmbH   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Carbachol; Detrusor contraction; Isomers; Metabolites; Propiverine; Smooth muscle

Indexed keywords

ATROPINE; CARBACHOL; DRUG METABOLITE; POTASSIUM CHLORIDE; PROPIVERINE;

ANIMAL TISSUE; ANTICHOLINERGIC EFFECT; ARTICLE; CALCIUM TRANSPORT; CIS ISOMER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETRUSOR MUSCLE; DRUG DETERMINATION; DRUG POTENCY; DRUG STRUCTURE; ELECTROSTIMULATION; ISOMERISM; MOUSE; NONHUMAN; PHARMACODYNAMICS; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; TRANS ISOMER;

ANIMALS; BENZILATES; CALCIUM; CARBACHOL; CHOLINERGIC ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; FEMALE; MALE; MICE; MICE, INBRED C57BL; MUSCLE CONTRACTION; POTASSIUM CHLORIDE; STEREOISOMERISM; SWINE; URINARY BLADDER;

EID: 77953230717     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0493-x     Document Type: Article

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