Effects of alendronate and strontium ranelate on cancellous and cortical bone mass in glucocorticoid-treated adult rats

Calcified Tissue International

Volumn 86, Issue 6, 2010, Pages 495-501

  Sun, P ^a   Cai, D H ^a   Li, Q N ^b   Chen, H ^a   Deng, W M ^c   He, L ^a   Yang, L ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^c GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

Author keywords

Alendronate; BMD; Glucocorticoid induced osteoporosis; Histomorphometry; Rats; Strontium ranelate

Indexed keywords

ALENDRONIC ACID; GLUCOCORTICOID; METHYLPREDNISOLONE; STRONTIUM RANELATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MASS; BONE STRUCTURE; BONE TISSUE; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; DIAPHYSIS; DRUG EFFICACY; DUAL ENERGY X RAY ABSORPTIOMETRY; LUMBAR VERTEBRA; MALE; METAPHYSIS; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOPENIA; PERIOSTEUM; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT; TIBIA; WEIGHT GAIN;

ABSORPTIOMETRY, PHOTON; ALENDRONATE; ANIMALS; BONE AND BONES; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; BONE DISEASES, METABOLIC; GLUCOCORTICOIDS; MALE; METHYLPREDNISOLONE; ORGANOMETALLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; THIOPHENES;

EID: 77953230156     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9363-2     Document Type: Article

References (36)

1. H Namkung-Matthai JP Seale K Brown, et al. 1998 Comparative effects of anti- inflammatory corticosteroids in human bone-derived osteoblast-like cells Eur Respir J 12 1327 1333 10.1183/09031936.98.12061327 1:CAS:528: DyaK1MXlt1Wrug%3D%3D 9877486 (Pubitemid 29011424)
2. P Sambrook D Hughes AE Nelson, et al. 2003 Osteocyte viability with glucocorticoid therapy: relation to histomorphometry Ann Rheum Dis 62 1215 1217 10.1136/ard.2003.008839 1:STN:280:DC%2BD3srpsFGltA%3D%3D 14644862 (Pubitemid 37500630)
3. N Takahashi T Sasaki Y Tsouderos, et al. 2003 S12911-2 inhibits osteoclastic bone resorption in vitro J Bone Miner Res 18 1082 1087 10.1359/jbmr.2003.18.6.1082 1:CAS:528:DC%2BD3sXkslOhsbk%3D 12817762 (Pubitemid 37294946)
4. G Mazziotti A Angeli JP Bilezikian, et al. 2006 Glucocorticoid-induced osteoporosis: an update Trends Endocrinol Metab 7 144 149 10.1016/j.tem.2006.03. 009
5. L Dalle Carbonare ME Arlot PM Chavassieux, et al. 2001 Comparison of trabecular bone microarchitecture and remodeling in glucocorticoid-induced and postmenopausal osteoporosis J Bone Miner Res 16 97 103 10.1359/jbmr.2001.16.1.97 1:STN:280:DC%2BD3M7jtVKltg%3D%3D 11149495
6. DW Dempster 1989 Bone histomorphometry in glucocorticoid-induced osteoporosis J Bone Miner Res 4 137 141 10.1002/jbmr.5650040202 1:CAS:528:DyaL1MXktFOktLg%3D 2658477
7. D Chappard E Legrand MF Basle, et al. 1996 Altered trabecular architecture induced by corticosteroids: a bone histomorphometric study J Bone Miner Res 11 676 685 10.1002/jbmr.5650110516 1:STN:280:DyaK2s%2Fht1Krsg%3D%3D 9157783
8. TP Van Staa HG Leufkens L Abenhaim, et al. 2000 Use of oral corticosteroids and risk of fractures J Bone Miner Res 15 993 1000 10.1359/jbmr.2000.15.6.993 10841167 (Pubitemid 30350061)
9. H Masaki T Miki 2006 The biochemical markers of bone in steroid (glucocorticoid)-induced osteoporosis (GIOP) Clin Calcium 16 51 60
10. RN De Nijs 2008 Glucocorticoid-induced osteoporosis: a review on pathophysiology and treatment options Minerva Med 99 23 43 18299694
11. L Mosekilde JS Thomsen MS Mackey, et al. 2000 Treatment with risedronate or alendronate prevents hind-limb immobilization-induced loss of bone density and strength in adult female rats Bone 27 639 645 10.1016/S8756-3282(00)00375-6 1:CAS:528:DC%2BD3cXosFygt7k%3D 11062350
12. KG Saag R Emkey TJ Schnitzer, et al. 1998 Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. Glucocorticoid-Induced Osteoporosis Intervention Study Group N Engl J Med 339 292 299 10.1056/NEJM199807303390502 1:CAS:528:DyaK1cXlsVOitr4%3D 9682041 (Pubitemid 28366417)
13. E Orwoll M Ettinger S Weiss, et al. 2000 Alendronate for the treatment of osteoporosis in men N Engl J Med 134 604 610 10.1056/NEJM200008313430902 (Pubitemid 30659471)
14. J Iwamoto A Seki T Takeda, et al. 2006 Comparative effects of risedronate and calcitriol on cancellous bone in rats with glucocorticoid-induced osteopenia J Nutr Sci Vitaminol (Tokyo) 52 212 217
15. S Lam K Zouzias 2007 Strontium ranelate for the management of osteoporosis Consult Pharm 23 531 537
16. O Cebesoy E Tutar KC Kose, et al. 2007 Effect of strontium ranelate on fracture healing in rat tibia Joint Bone Spine 74 590 593 10.1016/j.jbspin.2007. 01.034 17967557 (Pubitemid 350236018)
17. SD Bain C Jerome V Shen, et al. 2009 Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants Osteoporos Int 20 1417 1428 10.1007/s00198-008-0815-8 1:CAS:528:DC%2BD1MXotlyhurg%3D 19096745
18. M Hott P Deloffre Y Tsouderos, et al. 2003 S12911-2 reduced bone loss induced by short-term immobilization in rats Bone 33 115 123 10.1016/S8756-3282(03)00115-7 1:CAS:528:DC%2BD3sXmt1Kjsb8%3D 12919706 (Pubitemid 36952693)
19. PA Hulley MM Conradie CR Langeveldt, et al. 2002 Glucocorticoid induced osteoporosis in the rat is prevented by the tyrosine phosphatase inhibitor, sodium orthovanadate Bone 31 220 229 10.1016/S8756-3282(02)00807-4 1:CAS:528:DC%2BD38XltFWgs7o%3D 12110438 (Pubitemid 34754451)
20. P Ammann I Badoud S Barraud, et al. 2007 Treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength J Bone Miner Res 22 1419 1425 10.1359/jbmr.070607 1:CAS:528:DC%2BD2sXhtVynsLjO 17547534 (Pubitemid 351339686)
21. AM Parfitt MK Drezner FH Glorieux, et al. 1987 Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee J Bone Miner Res 2 595 610 10.1002/jbmr.5650020617 1:STN:280:DyaL1czjvVemsQ%3D%3D 3455637
22. T Ogoshi H Hagino S Fukata, et al. 2008 Influence of glucocorticoid on bone in 3-, 6-, and 12-month-old rats as determined by bone mass and histomorphometry Mod Rheumatol 18 55 61 10.1007/s10165-008-0096-2
23. CS King EC Weir CW Gundberg, et al. 1996 Effects of continuous glucocorticoid infusion on bone metabolism in the rat Calcif Tissue Int 59 184 191 10.1007/s002239900107 1:CAS:528:DyaK28XltlKntbo%3D 8694896 (Pubitemid 26275368)
24. J Iwamoto A Seki T Takeda, et al. 2008 Effects of combined administration of alfacalcidol and risedronate on cancellous and cortical bone mass of the tibia in glucocorticoid-treated young rats Chin J Physiol 51 121 128 1:CAS:528:DC%2BD1cXos1yqsb0%3D 18935906
25. 2 and risedronate on trabecular bone in glucocorticoid- treated rats: a bone histomorphometry study Yonsei Med J 50 189 194 10.3349/ymj.2009.50.2.189 1:CAS:528:DC%2BD1MXmt1Wgtrk%3D 19430549
26. E Shane V Addesso PB Namerow, et al. 2004 Alendronate versus calcitriol for the prevention of bone loss after cardiac transplantation N Engl J Med 350 767 776 10.1056/NEJMoa035617 1:CAS:528:DC%2BD2cXhsVems74%3D 14973216 (Pubitemid 38209646)
27. P Roschger S Rinnerthaler JA Yates, et al. 2001 Alendronate increases degree and uniformity of mineralisation in cancellous bone and decreases the porosity in cortical bone of osteoporotic women Bone 29 185 191 10.1016/S8756-3282(01)00485-9 1:CAS:528:DC%2BD3MXlvFWkurk%3D 11502482 (Pubitemid 32737191)
28. P Fratzl P Roschger N Fratzl-Zelman, et al. 2007 Evidence that treatment with risedronate in women with post menopausal osteoporosis affects bone mineralisation and bone volume Calcif Tissue Int 81 73 80 10.1007/s00223-007- 9039-8 1:CAS:528:DC%2BD2sXosFOgsrk%3D 17612779 (Pubitemid 47240833)
29. 2 and risedronate on bone formation and resorption, osteocyte lacunar system, and porosity in the cortical bone of glucocorticoid-treated rats Calcif Tissue Int 83 121 128 10.1007/s00223-008-9146-1 1:CAS:528:DC%2BD1cXhtVyisr7L 18543014
30. E Bonnelye A Chabadel F Saltel, et al. 2008 Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro Bone 42 129 138 10.1016/j.bone.2007.08.043 1:CAS:528:DC%2BD2sXhsVOrtr3E 17945546 (Pubitemid 350297175)
31. ME Arlot Y Jiang HK Genant, et al. 2008 Histomorphometric and microCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate J Bone Miner Res 23 215 222 10.1359/jbmr.071012 1:CAS:528:DC%2BD1cXhvVOhtr8%3D 17922612 (Pubitemid 351160035)
32. PJ Marie 2006 Strontium ranelate: a physiological approach for optimizing bone formation and resorption Bone 38 Suppl 1 10 14 10.1016/j.bone.2005.07.029 (Pubitemid 43190768)
33. PJ Marie M Hott D Modrowski, et al. 1993 An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats J Bone Miner Res 8 607 615 10.1002/jbmr.5650080512 1:CAS:528:DyaK2cXksFSjsbs%3D 8511988
34. PJ Marie M Hott 1986 Short-term effects of fluoride and strontium on bone formation and resorption in the mouse Metabolism 35 547 551 10.1016/0026-0495(86)90013-2 1:CAS:528:DyaL28XhvF2qt7o%3D 3713515 (Pubitemid 16090278)
35. G Boivin P Deloffre B Perrat, et al. 1996 Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration J Bone Miner Res 11 1302 1311 10.1002/jbmr.5650110915 1:CAS:528:DyaK28Xls1ChtLc%3D 8864905
36. M Grynpas PJ Marie 1990 Effects of low doses of strontium on bone quality and quantity in rats Bone 11 313 319 10.1016/8756-3282(90)90086-E 1:CAS:528:DyaK3MXksVyjtbo%3D 2252809 (Pubitemid 20326825)