Flibanserin, a drug intended for treatment of hypoactive sexual desire disorder in pre-menopausal women, affects spontaneous motor activity and brain neurochemistry in female rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 381, Issue 6, 2010, Pages 573-579

  Ferger, Boris ^a   Shimasaki, Makoto ^a   Ceci, Angelo ^a   Ittrich, Carina ^a   Allers, Kelly A ^a   Sommer, Bernd ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

8 OH DPAT; Flibanserin; HPLC; HSDD; Motor activity; Post mortem neurochemistry

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; FLIBANSERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; DOPAMINE METABOLISM; DRUG ACTIVITY; DRUG EFFICACY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOACTIVE SEXUAL DESIRE DISORDER; HYPOTHALAMUS; MOTOR ACTIVITY; NEUROCHEMISTRY; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PREMENOPAUSE; PSYCHOSEXUAL DISORDER; RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BENZIMIDAZOLES; BRAIN CHEMISTRY; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MOTOR ACTIVITY; NEUROTRANSMITTER AGENTS; RATS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN; SEXUAL DYSFUNCTIONS, PSYCHOLOGICAL;

EID: 77953216222     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0515-8     Document Type: Article

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