Chronic inhibition of nitric-oxide synthase induces hypertension and erectile dysfunction in the rat that is not reversed by sildenafil

BJU International

Volumn 106, Issue 1, 2010, Pages 78-83

  Gur, Serap ^a   Kadowitz, Philip J ^a   Gurkan, Levent ^a   Chandra, Surabhi ^a   Dewitt, Sharon Y ^a   Harbin, Andrew ^a   Sikka, Suresh C ^a   Agrawal, Krishna C ^a   Hellstrom, Wayne J G ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Erectile dysfunction; Hypertension; L NAME; Rat; Sildenafil

Indexed keywords

CYCLIC GMP; DRINKING WATER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; SILDENAFIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAVERNOUS NERVE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DRUG EFFECT; ELECTROSTIMULATION; ENDOTHELIUM; ENZYME DEFICIENCY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERECTILE DYSFUNCTION; FEEDING; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MEAN ARTERIAL PRESSURE; MUSCLE ISOMETRIC CONTRACTION; NERVE; NONHUMAN; PENIS ERECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RISK FACTOR; SMOOTH MUSCLE; TREATMENT OUTCOME; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERECTILE DYSFUNCTION; HYPERTENSION; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PENILE ERECTION; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES; PURINES; RATS; RATS, SPRAGUE-DAWLEY; SULFONES; UP-REGULATION;

EID: 77953211239     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2009.09104.x     Document Type: Article

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