메뉴 건너뛰기




Volumn 216, Issue 5, 2010, Pages 625-630

Distinct functionalities of bone morphogenetic protein antagonists during fracture healing in mice

Author keywords

Antagonists; Bone; Bone morphogenetic proteins; Fracture; Rodent

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN AND ACTIVIN MEMBRANE BOUND INHIBITOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CHORDIN; DIFFERENTIAL SCREENING SELECTED GENE ABERRANT IN NEUROBLASTOMA; NOGGIN; OSTEOGENIC PROTEIN 1; PROTEIN CERBERUS; PROTEIN GREM1; PROTEIN INHIBITOR; PROTEIN RELATED TO DAN AND CERBERUS; SCLEROSTIN; SMAD6 PROTEIN; SMAD7 PROTEIN; UNCLASSIFIED DRUG;

EID: 77953155768     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2010.01214.x     Document Type: Article
Times cited : (30)

References (33)
  • 1
    • 33744772589 scopus 로고    scopus 로고
    • Function of BMPs and BMP antagonists in adult bone
    • Abe E. Function of BMPs and BMP antagonists in adult bone. Ann N Y Acad Sci 2006, 1068:41-53.
    • (2006) Ann N Y Acad Sci , vol.1068 , pp. 41-53
    • Abe, E.1
  • 2
    • 0035101614 scopus 로고    scopus 로고
    • The bone morphogenetic proteins antagonist noggin inhibits membranous ossification
    • Aspenberg P, Jeppsson C, Economides AN. The bone morphogenetic proteins antagonist noggin inhibits membranous ossification. J Bone Miner Res 2001, 16:497-500.
    • (2001) J Bone Miner Res , vol.16 , pp. 497-500
    • Aspenberg, P.1    Jeppsson, C.2    Economides, A.N.3
  • 3
    • 0036399170 scopus 로고    scopus 로고
    • Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators
    • Balesman W, Van Hul W. Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators. Dev Biol 2002, 250:231-250.
    • (2002) Dev Biol , vol.250 , pp. 231-250
    • Balesman, W.1    Van Hul, W.2
  • 4
    • 34948907257 scopus 로고    scopus 로고
    • Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries
    • Chang K, Weiss D, Suo J. Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries. Circulation 2007, 116:1258-1266.
    • (2007) Circulation , vol.116 , pp. 1258-1266
    • Chang, K.1    Weiss, D.2    Suo, J.3
  • 5
    • 36549010603 scopus 로고    scopus 로고
    • Noggin is required for normal lobe patterning and ductal budding in the mouse prostate
    • Cook C, Vezina CM, Allgeier SH. Noggin is required for normal lobe patterning and ductal budding in the mouse prostate. Dev Biol 2007, 312:217-230.
    • (2007) Dev Biol , vol.312 , pp. 217-230
    • Cook, C.1    Vezina, C.M.2    Allgeier, S.H.3
  • 6
    • 85045483986 scopus 로고    scopus 로고
    • Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review
    • iii-iv
    • Garrison KR, Donell S, Ryder J. Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review. Health Technol Assess 2007, 11:1-150. iii-iv
    • (2007) Health Technol Assess , vol.11 , pp. 1-150
    • Garrison, K.R.1    Donell, S.2    Ryder, J.3
  • 7
    • 33846004405 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their antagonists
    • Gazzerro E, Canalis E. Bone morphogenetic proteins and their antagonists. Rev Endocr Metab Disord 2006, 7:51-65.
    • (2006) Rev Endocr Metab Disord , vol.7 , pp. 51-65
    • Gazzerro, E.1    Canalis, E.2
  • 8
    • 34248371651 scopus 로고    scopus 로고
    • Potential drug targets within bone morphogenetic protein signaling pathways
    • Gazzerro E, Minetti C. Potential drug targets within bone morphogenetic protein signaling pathways. Curr Opin Pharmacol 2007, 7:325-333.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 325-333
    • Gazzerro, E.1    Minetti, C.2
  • 9
    • 0035141917 scopus 로고    scopus 로고
    • Bambi is coexpressed with Bmp-4 during mouse embryogenesis
    • Grotewold L, Plum M, Dildrop R. Bambi is coexpressed with Bmp-4 during mouse embryogenesis. Mech Dev 2001, 100:327-330.
    • (2001) Mech Dev , vol.100 , pp. 327-330
    • Grotewold, L.1    Plum, M.2    Dildrop, R.3
  • 10
    • 43149098504 scopus 로고    scopus 로고
    • Characterizing the BMP pathway in a wild type mouse model of distraction osteogenesis
    • Haque T, Hamade F, Alam N. Characterizing the BMP pathway in a wild type mouse model of distraction osteogenesis. Bone 2008, 42:1144-1153.
    • (2008) Bone , vol.42 , pp. 1144-1153
    • Haque, T.1    Hamade, F.2    Alam, N.3
  • 11
    • 43449133564 scopus 로고    scopus 로고
    • Expression and regulation of the decoy bone morphogenetic protein receptor BAMBI in the developing avian face
    • Higashihori N, Song Y, Richman JM. Expression and regulation of the decoy bone morphogenetic protein receptor BAMBI in the developing avian face. Dev Dyn 2008, 237:1500-1508.
    • (2008) Dev Dyn , vol.237 , pp. 1500-1508
    • Higashihori, N.1    Song, Y.2    Richman, J.M.3
  • 12
    • 0027558772 scopus 로고
    • A standardized experimental fracture in the mouse tibia
    • Hiltunen A, Vuorio E, Aro HT. A standardized experimental fracture in the mouse tibia. J Orthop Res 1993, 11:305-312.
    • (1993) J Orthop Res , vol.11 , pp. 305-312
    • Hiltunen, A.1    Vuorio, E.2    Aro, H.T.3
  • 13
    • 33745713060 scopus 로고    scopus 로고
    • Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial
    • Jones AL, Bucholz RW, Bosse MJ. Recombinant human BMP-2 and allograft compared with autogenous bone graft for reconstruction of diaphyseal tibial fractures with cortical defects. A randomized, controlled trial. J Bone Joint Surg Am 2006, 88:1431-1441.
    • (2006) J Bone Joint Surg Am , vol.88 , pp. 1431-1441
    • Jones, A.L.1    Bucholz, R.W.2    Bosse, M.J.3
  • 14
    • 42149091190 scopus 로고    scopus 로고
    • The BMP signaling and its Smads in mandibular distraction osteogenesis
    • Khanal A, Yoshioka I, Tominaga K. The BMP signaling and its Smads in mandibular distraction osteogenesis. Oral Dis 2008, 14:347-355.
    • (2008) Oral Dis , vol.14 , pp. 347-355
    • Khanal, A.1    Yoshioka, I.2    Tominaga, K.3
  • 15
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: new members, new receptors and new genetic tests of function in different organisms
    • Kingsley DM. The TGF-beta superfamily: new members, new receptors and new genetic tests of function in different organisms. Genes Dev 1994, 8:133-146.
    • (1994) Genes Dev , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 16
    • 0042834336 scopus 로고    scopus 로고
    • BMP signaling components are expressed in human fracture callus
    • Kloen P, Di Paola M, Borens O. BMP signaling components are expressed in human fracture callus. Bone 2003, 33:362-371.
    • (2003) Bone , vol.33 , pp. 362-371
    • Kloen, P.1    Di Paola, M.2    Borens, O.3
  • 17
    • 45749094563 scopus 로고    scopus 로고
    • Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells
    • Kwong FN, Richardson SM, Evans CH. Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells. Arthritis Res Ther 2008, 10:R65.
    • (2008) Arthritis Res Ther , vol.10
    • Kwong, F.N.1    Richardson, S.M.2    Evans, C.H.3
  • 18
    • 41549140416 scopus 로고    scopus 로고
    • An improved murine femur fracture device for bone healing studies
    • Marturano JE, Cleveland BC, Byrne MA. An improved murine femur fracture device for bone healing studies. J Biomech 2008, 41:1222-1228.
    • (2008) J Biomech , vol.41 , pp. 1222-1228
    • Marturano, J.E.1    Cleveland, B.C.2    Byrne, M.A.3
  • 19
    • 0032523777 scopus 로고    scopus 로고
    • Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
    • McMahon JA, Takada S, Zimmerman LB. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev 1998, 12:1438-1452.
    • (1998) Genes Dev , vol.12 , pp. 1438-1452
    • McMahon, J.A.1    Takada, S.2    Zimmerman, L.B.3
  • 20
    • 0034659784 scopus 로고    scopus 로고
    • M-1/M-2 macrophages and the Th1/Th2 paradigm
    • Mills CD, Kincaid K, Alt JM. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol 2000, 164:6166-6173.
    • (2000) J Immunol , vol.164 , pp. 6166-6173
    • Mills, C.D.1    Kincaid, K.2    Alt, J.M.3
  • 21
    • 50249186349 scopus 로고    scopus 로고
    • BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment
    • Mine N, Anderson RM, Klingensmith J. BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment. Development 2008, 135:2425-2434.
    • (2008) Development , vol.135 , pp. 2425-2434
    • Mine, N.1    Anderson, R.M.2    Klingensmith, J.3
  • 22
    • 0142147985 scopus 로고    scopus 로고
    • Temporal and spatial expression profiles of BMP receptors and noggin during BMP-2 induced ectopic bone formation
    • Nakamura N, Wakitani S, Nakayama J. Temporal and spatial expression profiles of BMP receptors and noggin during BMP-2 induced ectopic bone formation. J Bone Miner Res 2003, 18:1854-1862.
    • (2003) J Bone Miner Res , vol.18 , pp. 1854-1862
    • Nakamura, N.1    Wakitani, S.2    Nakayama, J.3
  • 23
    • 33746134510 scopus 로고    scopus 로고
    • Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures
    • Niikura T, Hak DJ, Reddi AH. Global gene profiling reveals a downregulation of BMP gene expression in experimental atrophic nonunions compared to standard healing fractures. J Orthop Res 2006, 24:1463-1471.
    • (2006) J Orthop Res , vol.24 , pp. 1463-1471
    • Niikura, T.1    Hak, D.J.2    Reddi, A.H.3
  • 24
    • 0033619255 scopus 로고    scopus 로고
    • Silencing of TGF-beta signaling by the pseudoreceptor BAMBI
    • Onichtchouk D, Chen YG, Dosch R. Silencing of TGF-beta signaling by the pseudoreceptor BAMBI. Nature 1999, 401:480-485.
    • (1999) Nature , vol.401 , pp. 480-485
    • Onichtchouk, D.1    Chen, Y.G.2    Dosch, R.3
  • 25
    • 33744727364 scopus 로고    scopus 로고
    • BMP and BMP inhibitors in bone
    • Rosen V. BMP and BMP inhibitors in bone. Ann NY Acad Sci 2006, 1068:19-25.
    • (2006) Ann NY Acad Sci , vol.1068 , pp. 19-25
    • Rosen, V.1
  • 26
    • 33847402760 scopus 로고    scopus 로고
    • Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor
    • Stabile H, Mitola S, Moroni E. Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor. Blood 2007, 109:1834-1840.
    • (2007) Blood , vol.109 , pp. 1834-1840
    • Stabile, H.1    Mitola, S.2    Moroni, E.3
  • 27
    • 33947305450 scopus 로고    scopus 로고
    • Molecular aspects of fracture healing: which are the important molecules?
    • Tsiridis E, Upadhyay N, Giannoudis P. Molecular aspects of fracture healing: which are the important molecules? Injury 2007, 38(S1):S11-S25.
    • (2007) Injury , vol.38 , Issue.1 S
    • Tsiridis, E.1    Upadhyay, N.2    Giannoudis, P.3
  • 28
    • 33751506452 scopus 로고    scopus 로고
    • BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
    • Tsuji K, Bandyopadhyay A, Harfe BD. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 2006, 38:1424-1428.
    • (2006) Nat Genet , vol.38 , pp. 1424-1428
    • Tsuji, K.1    Bandyopadhyay, A.2    Harfe, B.D.3
  • 29
    • 40149086548 scopus 로고    scopus 로고
    • BMP4 is dispensable for skeletogenesis and fracture-healing in the limb
    • Tsuji K, Cox K, Bandyopadhyay A. BMP4 is dispensable for skeletogenesis and fracture-healing in the limb. J Bone Joint Surg Am 2008, 90(Suppl 1):14-18.
    • (2008) J Bone Joint Surg Am , vol.90 , Issue.1 SUPPL. , pp. 14-18
    • Tsuji, K.1    Cox, K.2    Bandyopadhyay, A.3
  • 30
    • 35748948100 scopus 로고    scopus 로고
    • Bone morphogenic protein and its application in trauma cases: a current concept update
    • Vaibhav B, Nilesh P, Vikram S. Bone morphogenic protein and its application in trauma cases: a current concept update. Injury 2007, 38:1227-1235.
    • (2007) Injury , vol.38 , pp. 1227-1235
    • Vaibhav, B.1    Nilesh, P.2    Vikram, S.3
  • 31
    • 34548842204 scopus 로고    scopus 로고
    • Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation
    • Wan DC, Pomerantz JH, Brunet LJ. Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. J Biol Chem 2007, 282:26450-26459.
    • (2007) J Biol Chem , vol.282 , pp. 26450-26459
    • Wan, D.C.1    Pomerantz, J.H.2    Brunet, L.J.3
  • 32
    • 33645956528 scopus 로고    scopus 로고
    • Bone morphogenetic proteins 5 and 6 stimulate osteoclast generation
    • Wutzl A, Brozek W, Lernbass I. Bone morphogenetic proteins 5 and 6 stimulate osteoclast generation. J Biomed Mater Res (A) 2006, 77:75-83.
    • (2006) J Biomed Mater Res (A) , vol.77 , pp. 75-83
    • Wutzl, A.1    Brozek, W.2    Lernbass, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.