Adenovirus-mediated stromal cell-derived factor-1 alpha gene transfer improves cardiac structure and function after experimental myocardial infarction through angiogenic and antifibrotic actions

Molecular Biology Reports

Volumn 37, Issue 4, 2010, Pages 1957-1969

  Tang, Junming ^a,b,c   Wang, Jianing ^a,c   Song, Hongxian ^a,c   Huang, Yongzhang ^a,c   Yang, Jianye ^a,c   Kong, Xia ^a,c   Guo, Linyun ^a,c   Zheng, Fei ^a,c   Zhang, Lei ^a,c  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

^c Key Lab of Human Embryonic Stem Cell of Hubei Province   (China)

Author keywords

Angiogenesis; Myocardial infarction; Remodeling; SDF 1 ; Stem cell; TIMP

Indexed keywords

ADENOVIRUS VECTOR; BASIC FIBROBLAST GROWTH FACTOR; BETA GALACTOSIDASE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; MESSENGER RNA; PHOSPHATE BUFFERED SALINE; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1ALPHA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL HOMING; CONTROLLED STUDY; DRUG MECHANISM; DRUG TISSUE LEVEL; GENE EXPRESSION; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART LEFT VENTRICLE WALL; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; MALE; NONHUMAN; RAT; STEM CELL; SYSTOLIC BLOOD PRESSURE; VIRAL GENE DELIVERY SYSTEM; ADENOVIRUS; ANIMAL; CELL MOTION; CELL SURVIVAL; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; HEART FUNCTION TEST; HEART MUSCLE; HEMODYNAMICS; HUMAN; LEUKOCYTE COUNT; METABOLISM; MONONUCLEAR CELL; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

ADENOVIRIDAE; RATTUS;

ADENOVIRIDAE; ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; CELL SURVIVAL; CHEMOKINE CXCL12; ENDOMYOCARDIAL FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HEART FUNCTION TESTS; HEMODYNAMICS; HUMANS; LEUKOCYTE COUNT; LEUKOCYTES, MONONUCLEAR; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS;

EID: 77953141744     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9642-z     Document Type: Article

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