Development of an in vitro model for radiation-induced effects on oral keratinocytes

International Journal of Oral and Maxillofacial Surgery

Volumn 39, Issue 4, 2010, Pages 364-370

  Tobita, T ^a   Izumi, K ^b,c   Feinberg, S E ^c  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

in vitro assay system; organotypic culture; pro inflammatory cytokine; radiation induced oral mucositis

Indexed keywords

FORMALDEHYDE; INTERLEUKIN 1ALPHA; INTERLEUKIN 8;

ARTICLE; BASAL CELL; CELL CULTURE; CELL DAMAGE; CELL PROLIFERATION; CELL VIABILITY; CELLS AND CELL COMPONENTS; CLINICAL ARTICLE; COLONY FORMING UNIT; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EX VIVO STUDY; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KERATINOCYTE; MALE; MONOLAYER CULTURE; MOUTH INFLAMMATION; RADIATION DOSE;

BIOCOMPATIBLE MATERIALS; CELL ADHESION; CELL COUNT; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; COLLAGEN; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1ALPHA; INTERLEUKIN-8; KERATINOCYTES; KI-67 ANTIGEN; MALE; MOUTH MUCOSA; RADIATION DOSAGE; STOMATITIS; TETRAZOLIUM SALTS; THIAZOLES; TISSUE SCAFFOLDS;

EID: 77953135537     PISSN: 09015027     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijom.2009.12.020     Document Type: Article

References (24)

1. Abbott A. Cell culture: biology's new dimension. Nature 424 (2003) 870-872
2. Antin J.H., and Ferrara J.L. Cytokine dysregulation and acute graft-versus-host disease. Blood 80 (1992) 2964-2968
3. Barker J.N., Mitra R.S., Griffiths C.E., Dixit V.M., and Nickoloff B.J. Keratinocytes as initiators of inflammation. Lancet 337 (1991) 211-214
4. Bettinger C., and Zimmermann H.W. New investigations on hematoxylin, hematein, and hematein-aluminium complexes. Histochemistry 96 (1991) 215-228
5. Cory A.H., Owen T.C., Barltrop J.A., and Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 3 (1991) 207-212
6. Dorr W., Emmendorfer H., Haide E., and Kummermehr J. Proliferation equivalent of 'accelerated repopulation' in mouse oral mucosa. Int J Radiat Biol 66 (1994) 157-167
7. Doucet O., Robert C., and Zastrow L. Use of a serum-free reconstituted epidermis as a skin pharmacological model. Toxicol In Vitro 10 (1996) 305-313
8. Gerdes J., Schwab U., Lemke H., and Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31 (1983) 13-20
9. Hoye A.T., Davoren J.E., Wipf P., Fink M.P., and Kagan V.E. Targeting mitochondria. Acc Chem Res 41 (2008) 87-97
10. Izumi K., Song J., and Feinberg S.E. Development of a tissue engineered human oral mucosa: from the bench to the bed side. Cells Tissues Organs 176 (2004) 134-152
11. Logan R.M., Stringer A.M., Bowen J.M., Yeoh A.S.-J., Gibson R.J., Sonis S.T., and Keefe D.M.K. The role of pro-inflammatory cytokines in cancer treatment-induced alimentary tract mucositis: pathobiology, animal models and cytotoxic drugs. Cancer Treatment Rev 33 (2007) 448-460
12. McKenzie R.C., and Sauder D.N. The role of keratinocyte cytokines in inflammation and immunity. J Invest Dermatol 95 (1990) 105S-107S
13. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65 (1983) 55-63
14. Nelson D., and Gay R.J. Effects of UV irradiation on a living skin equivalent. Photochem Photobiol 57 (1993) 830-837
15. Ponec M. Skin constructs for replacement of skin tissues for in vitro testing. Adv Drug Deliv Rev 54 Suppl. 1 (2002) S19-S30
16. Slonina D., Hoinkis C., and Dorr W. Effect of keratinocyte growth factor on radiation survival and colony size of human epidermal keratinocytes in vitro. Radiat Res 156 (2001) 761-766
17. Smith A.A. Specific staining of tissue components with metal-hematoxylin complexes. Micron 33 (2002) 95-103
18. Sonis S.T. The pathobiology of mucositis. Nat Rev Cancer 4 (2004) 277-284
19. Sonis S.T. Pathobiology of oral mucositis: novel insights and opportunities. J Support Oncol 9 Suppl. 4 (2007) 3-11
20. Stiff P. Mucositis associated with stem cell transplantation: current status and innovative approaches to management. Bone Marrow Transplant 27 Suppl. 2 (2001) S3-S11
21. Xu Q., Izumi K., Tobita T., Nakanishi Y., and Feinberg S.E. Constitutive release of cytokines by human oral keratinocytes in an organotypic culture. J Oral Maxillofac Surg 67 (2009) 1256-1264
22. Xun C.Q., Thompson J.S., Jennings C.D., Brown S.A., and Widmer M.B. Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice. Blood 83 (1994) 2360-2367
23. Yeoh A., Gibson R., Yeoh E., Bowen J., Stringer A., Giam K., Logan R., and Keefe D. Radiation therapy-induced mucositis: relationships between fractionated radiation, NF-κB, COX-1, and COX-2. Cancer Treatment Rev 32 (2006) 645-651
24. Zaghloul M.S., Dorie M.J., and Kallman R.F. Interleukin-1 modulatory effect on the action of chemotherapeutic drugs and localized irradiation of the lip, duodenum, and tumor. Int J Radiat Oncol Biol Phys 26 (1993) 417-425